IMP

Process View

Rattus norvegicus

12 genes annotated in rat

dendritic spine organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in rat Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "dendritic spine organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dendritic spine organization" (in gray)

Name	Description	Probability	Func Analog Organism
Gria2	glutamate receptor, ionotropic, AMPA 2	0.490
Gria1	glutamate receptor, ionotropic, AMPA 1	0.456
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.360
Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	0.260
Pfn1	profilin 1	0.223
Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.152
Sec23a	Sec23 homolog A (S. cerevisiae)	0.147
Grip1	glutamate receptor interacting protein 1	0.138
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.136
Nlgn2	neuroligin 2	0.132
Gnb2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.130
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.126
Cttn	cortactin	0.106
Lin7b	lin-7 homolog b (C. elegans)	0.088
Homer1	homer homolog 1 (Drosophila)	0.084
Cnksr2	connector enhancer of kinase suppressor of Ras 2	0.081
Prkce	protein kinase C, epsilon	0.074
Grin2a	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.064
Csrp3	cysteine and glycine-rich protein 3	0.051
Nsf	N-ethylmaleimide-sensitive factor	0.050
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.048
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.045
Wdr1	WD repeat domain 1	0.042
Prkca	protein kinase C, alpha	0.040
Dlg2	discs, large homolog 2 (Drosophila)	0.039	Rat
Efhd2	EF-hand domain family, member D2	0.039
Tspyl1	TSPY-like 1	0.032
Efnb2	ephrin B2	0.029
Sh3gl2	SH3-domain GRB2-like 2	0.029
Baiap2	BAI1-associated protein 2	0.028
Nfix	nuclear factor I/X (CCAAT-binding transcription factor)	0.028
Ate1	arginyltransferase 1	0.027
Copb1	coatomer protein complex, subunit beta 1	0.026
Map2	microtubule-associated protein 2	0.026
Prelid1	PRELI domain containing 1	0.026
Gosr1	golgi SNAP receptor complex member 1	0.026
Dlg3	discs, large homolog 3 (Drosophila)	0.025	Rat
Gabra5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	0.025
Grin1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.025
Atp6v0c	ATPase, H+ transporting, lysosomal V0 subunit C	0.024
Rab15	RAB15, member RAS oncogene family	0.024
Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.023
Vamp2	vesicle-associated membrane protein 2	0.022
Gria3	glutamate receptor, ionotrophic, AMPA 3	0.021
Rab6a	RAB6A, member RAS oncogene family	0.021
Dlg4	discs, large homolog 4 (Drosophila)	0.021
Fkbp1a	FK506 binding protein 1a	0.020
Tagln2	transgelin 2	0.020
Npdc1	neural proliferation, differentiation and control, 1	0.020
Ryr2	ryanodine receptor 2, cardiac	0.020
Litaf	lipopolysaccharide-induced TNF factor	0.020
Atf2	activating transcription factor 2	0.020
Ipp	intracisternal A particle-promoted polypeptide	0.019
Rabac1	Rab acceptor 1 (prenylated)	0.019
Sdk2	sidekick homolog 2 (chicken)	0.018
Apc	adenomatous polyposis coli	0.018
Rab4b	RAB4B, member RAS oncogene family	0.017
Serinc1	serine incorporator 1	0.017
Mink1	misshapen-like kinase 1 (zebrafish)	0.017
Clcn2	chloride channel 2	0.016
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.016
Pds5a	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.016
Calr	calreticulin	0.016
Fam45a	family with sequence similarity 45, member A	0.015
Arcn1	archain 1	0.015
Fkbp1b	FK506 binding protein 1b	0.015
Epha7	Eph receptor A7	0.014	Rat
RGD1311122	similar to RIKEN cDNA 1110003E01	0.014
Adam10	ADAM metallopeptidase domain 10	0.014
Ntm	neurotrimin	0.013
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.013
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.013
Pafah1b2	platelet-activating factor acetylhydrolase, isoform 1b, subunit 2	0.012
Mapk10	mitogen activated protein kinase 10	0.012
Slc35b1	solute carrier family 35, member B1	0.012
Top1	topoisomerase (DNA) I	0.012
Rdh2	retinol dehydrogenase 2	0.012
Nlgn1	neuroligin 1	0.012
RGD1311493	similar to CG13379-PA	0.012
Kctd3	potassium channel tetramerisation domain containing 3	0.012
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.012
Ppp2r4	protein phosphatase 2A activator, regulatory subunit 4	0.011
Gpr155	G protein-coupled receptor 155	0.011
Dctn4	dynactin 4	0.011
Pou3f3	POU class 3 homeobox 3	0.011
Madd	MAP-kinase activating death domain	0.011
Bsn	bassoon	0.011
Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	0.011
Prkcb	protein kinase C, beta	0.011
PVR	poliovirus receptor	0.011
Ehd4	EH-domain containing 4	0.011
Lrch4	leucine-rich repeats and calponin homology (CH) domain containing 4	0.011
Atp2b3	ATPase, Ca++ transporting, plasma membrane 3	0.011
Shank2	SH3 and multiple ankyrin repeat domains 2	0.011
Ntf4	neurotrophin 4	0.011
Stx6	syntaxin 6	0.011
Csnk1g3	casein kinase 1, gamma 3	0.011
Ap1s1	adaptor-related protein complex 1, sigma 1 subunit	0.010
Lrfn2	leucine rich repeat and fibronectin type III domain containing 2	0.010
Dgki	diacylglycerol kinase, iota	0.010
Pols	polymerase (DNA directed) sigma	0.010
Wdr54	WD repeat domain 54	0.010
Pcsk2	proprotein convertase subtilisin/kexin type 2	0.010