IMP

Process View

Rattus norvegicus

10 genes annotated in rat

serotonin receptor signaling pathway

The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in rat Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "serotonin receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "serotonin receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Chrne	cholinergic receptor, nicotinic, epsilon	0.436	Rat
Chrna1	cholinergic receptor, nicotinic, alpha 1 (muscle)	0.380	Rat
Slc6a7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.202
Aif1l	allograft inflammatory factor 1-like	0.185
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.145	Rat
Fgf14	fibroblast growth factor 14	0.136
Gcm1	glial cells missing homolog 1 (Drosophila)	0.136
Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7	0.134
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.125
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.121
Grik3	glutamate receptor, ionotropic, kainate 3	0.114
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.106
Mc5r	melanocortin 5 receptor	0.105
Olr416	olfactory receptor 416	0.105
Svs3a	seminal vesicle secretory protein 3A	0.098
Lim2	lens intrinsic membrane protein 2	0.095
Grik1	glutamate receptor, ionotropic, kainate 1	0.092
Slc16a8	solute carrier family 16, member 8 (monocarboxylic acid transporter 3)	0.091
Gabbr1	gamma-aminobutyric acid (GABA) B receptor 1	0.084
Cntn2	contactin 2 (axonal)	0.083
Rin1	Ras and Rab interactor 1	0.081
Syt8	synaptotagmin VIII	0.079
Sstr5	somatostatin receptor 5	0.078
Slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.078
Ar	androgen receptor	0.077
Ccbp2	chemokine binding protein 2	0.073
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.070
Avpr1b	arginine vasopressin receptor 1B	0.067
Vom2r27	vomeronasal 2 receptor, 27	0.067
Vom2r53	vomeronasal 2 receptor, 53	0.066
Zp1	zona pellucida glycoprotein 1 (sperm receptor)	0.065
Olr1500	olfactory receptor 1500	0.063
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.062
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.062
Gja3	gap junction protein, alpha 3	0.061
Myh3	myosin, heavy chain 3, skeletal muscle, embryonic	0.059
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.057
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.057
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.055
Chrnb2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.055	Rat
Plcd4	phospholipase C, delta 4	0.055
Oprl1	opiate receptor-like 1	0.051
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.050
Phkg1	phosphorylase kinase, gamma 1	0.047
Npy5r	neuropeptide Y receptor Y5	0.046
Tacr2	tachykinin receptor 2	0.046
Mmp13	matrix metallopeptidase 13	0.046
Cckar	cholecystokinin A receptor	0.045
Spt1	salivary protein 1	0.045
Ddn	dendrin	0.044
RGD1559748	similar to Palate lung and nasal carcinoma-like protein precursor (Tongue plunc-like protein)	0.042
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.041
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.041
Tore	trispanning orphan	0.039
Uncx	UNC homeobox	0.039
Smad3	SMAD family member 3	0.037
Atxn1	ataxin 1	0.036
Oprk1	opioid receptor, kappa 1	0.036
Kl	Klotho	0.036
Svs1	seminal vesicle secretory protein 1	0.036
Chrnb1	cholinergic receptor, nicotinic, beta 1 (muscle)	0.035	Rat
Il13	interleukin 13	0.035
Crisp1	cysteine-rich secretory protein 1	0.035
Krt4	keratin 4	0.035
Odf4	outer dense fiber of sperm tails 4	0.034
Cpne9	copine family member IX	0.034
Crx	cone-rod homeobox	0.034
Grm6	glutamate receptor, metabotropic 6	0.034
Omp	olfactory marker protein	0.034
Prp15	proline-rich protein 15	0.034
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.033
Vom1r93	vomeronasal 1 receptor 93	0.033
Ifnb1	interferon beta 1, fibroblast	0.032
Chrng	cholinergic receptor, nicotinic, gamma	0.032
Pth	parathyroid hormone	0.032
Il2ra	interleukin 2 receptor, alpha	0.031
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.031
Fgf7	fibroblast growth factor 7	0.031
Scn5a	sodium channel, voltage-gated, type V, alpha subunit	0.031
Pomc	proopiomelanocortin	0.030
Gabra4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.030
Rgs8	regulator of G-protein signaling 8	0.030
Grid2	glutamate receptor, ionotropic, delta 2	0.029
Ncan	neurocan	0.028
Gfra2	GDNF family receptor alpha 2	0.028
Grm2	glutamate receptor, metabotropic 2	0.028
Cyss	cystatin S	0.027
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.027
Mr1	major histocompatibility complex, class I-related	0.027
Cnga2	cyclic nucleotide gated channel alpha 2	0.027
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.027
Gabrp	gamma-aminobutyric acid (GABA-A) receptor, pi	0.026
Isl2	ISL LIM homeobox 2	0.026
Npy1r	neuropeptide Y receptor Y1	0.026
Olr1082	olfactory receptor 1082	0.026
Drd2	dopamine receptor D2	0.026
Prl	prolactin	0.026
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.026
Syt4	synaptotagmin IV	0.026
Cacnb4	calcium channel, voltage-dependent, beta 4 subunit	0.026
Naaladl1	N-acetylated alpha-linked acidic dipeptidase-like 1	0.026
Oprd1	opioid receptor, delta 1	0.026
LOC286987	hemiferrin, transferrin-like protein	0.025
Kcna6	potassium voltage gated channel, shaker related subfamily, member 6	0.025
Neurog3	neurogenin 3	0.024
Gabra3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.024
Grp	gastrin releasing peptide	0.024
Hrh3	histamine receptor H3	0.024
Cryba1	crystallin, beta A1	0.024
Ucn	urocortin	0.024
Lalba	lactalbumin, alpha	0.024
Olr287	olfactory receptor 287	0.023
Pde1b	phosphodiesterase 1B, calmodulin-dependent	0.023
Slc8a3	solute carrier family 8 (sodium/calcium exchanger), member 3	0.023
Rgs9	regulator of G-protein signaling 9	0.023
Cuzd1	CUB and zona pellucida-like domains 1	0.023
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.022
Tacr3	tachykinin receptor 3	0.022
Acr	acrosin	0.022
Lrrc7	leucine rich repeat containing 7	0.022
Ptgfr	prostaglandin F receptor	0.022
Cga	glycoprotein hormones, alpha polypeptide	0.021
Slc6a11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.021
Hapln1	hyaluronan and proteoglycan link protein 1	0.021
Pitx3	paired-like homeodomain 3	0.021
Mmp10	matrix metallopeptidase 10	0.021
Crhr2	corticotropin releasing hormone receptor 2	0.021
Olr1361	olfactory receptor 1361	0.021
Synpo	synaptopodin	0.021
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.021
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.021
Sstr4	somatostatin receptor 4	0.021
Kcnj9	potassium inwardly-rectifying channel, subfamily J, member 9	0.021
N5	DNA binding protein N5	0.021
Gabre	gamma-aminobutyric acid (GABA) A receptor, epsilon	0.021
Psg29	pregnancy-specific glycoprotein 29	0.020
Gdnf	glial cell derived neurotrophic factor	0.020
Adam2	ADAM metallopeptidase domain 2	0.020
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.020
Kcnc2	potassium voltage gated channel, Shaw-related subfamily, member 2	0.020
Adarb2	adenosine deaminase, RNA-specific, B2	0.020
Gpr12	G protein-coupled receptor 12	0.020
LOC60591	calcium-activated potassium channel beta subunit	0.020
Tpbpa	trophoblast specific protein alpha	0.020
Tbx19	T-box 19	0.020
Dpysl3	dihydropyrimidinase-like 3	0.019
Prss2	protease, serine, 2	0.019
Mmp9	matrix metallopeptidase 9	0.019
Cntn5	contactin 5	0.019
Drd5	dopamine receptor D5	0.019
Mpp2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	0.019
Olr1641	olfactory receptor 1641	0.019
Arpp21	cAMP-regulated phosphoprotein 21	0.019
Cd46	CD46 molecule, complement regulatory protein	0.018
Neu2	sialidase 2 (cytosolic sialidase)	0.018
Opn1sw	opsin 1 (cone pigments), short-wave-sensitive	0.018
Cx3cr1	chemokine (C-X3-C motif) receptor 1	0.018
Ly6b	lymphocyte antigen 6 complex, locus B	0.018
Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	0.018
Hrh2	histamine receptor H 2	0.018	Rat
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.018
Nxph1	neurexophilin 1	0.018
Col10a1	collagen, type X, alpha 1	0.018
Trhr2	thyrotropin releasing hormone receptor 2	0.018
Vip	vasoactive intestinal peptide	0.017
Chrm5	cholinergic receptor, muscarinic 5	0.017
Ctf1	cardiotrophin 1	0.017
Crhbp	corticotropin releasing hormone binding protein	0.017
RGD1565859	RGD1565859	0.017
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.017
Clcn1	chloride channel 1	0.017
Scn2b	sodium channel, voltage-gated, type II, beta	0.017
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.017
Prss1	protease, serine, 1 (trypsin 1)	0.017
Sstr3	somatostatin receptor 3	0.017
Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	0.017
Adcyap1r1	adenylate cyclase activating polypeptide 1 receptor 1	0.017
Gria4	glutamate receptor, ionotrophic, AMPA 4	0.017
Folh1	folate hydrolase 1	0.017
Edn2	endothelin 2	0.017
Hcrtr2	hypocretin (orexin) receptor 2	0.017
Mchr1	melanin-concentrating hormone receptor 1	0.017
RGD1564327	similar to integrin alpha 8	0.017
Slc1a6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.017
Chrna4	cholinergic receptor, nicotinic, alpha 4	0.016	Rat
Rph3a	rabphilin 3A	0.016
Csf3	colony stimulating factor 3 (granulocyte)	0.016
Myt1l	myelin transcription factor 1-like	0.016
Prrxl1	paired related homeobox protein-like 1	0.016
Asph	aspartate-beta-hydroxylase	0.016
Tacr1	tachykinin receptor 1	0.016
Atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.016
Accn3	amiloride-sensitive cation channel 3	0.016
Gpr83	G protein-coupled receptor 83	0.016
Strn	striatin, calmodulin binding protein	0.016
Olr1078	olfactory receptor 1078	0.016
Edn1	endothelin 1	0.016
Cryba4	crystallin, beta A4	0.015
Tpsb2	tryptase beta 2	0.015
Gzmk	granzyme K	0.015
Crp	C-reactive protein, pentraxin-related	0.015
Prkcg	protein kinase C, gamma	0.015
Aifm3	apoptosis-inducing factor, mitochondrion-associated 3	0.015
Hnmt	histamine N-methyltransferase	0.015
Gad2	glutamate decarboxylase 2	0.015
Olr1493	olfactory receptor gene Olr1493	0.015
Fgf8	fibroblast growth factor 8	0.015
Slc9a4	solute carrier family 9 (sodium/hydrogen exchanger), member 4	0.015
Pnliprp1	pancreatic lipase-related protein 1	0.015
Htr3a	5-hydroxytryptamine (serotonin) receptor 3a	0.015	Human
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.015
RGD1564664	similar to LOC387763 protein	0.014
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.014
Ptafr	platelet-activating factor receptor	0.014
Csrnp2	cysteine-serine-rich nuclear protein 2	0.014
Cxcl6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.014
Gper	G protein-coupled estrogen receptor 1	0.014
Adam3a	ADAM metallopeptidase domain 3A (cyritestin 1)	0.014
Scn8a	sodium channel, voltage gated, type VIII, alpha subunit	0.014
Apba1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.014
Mybph	myosin binding protein H	0.014
Tnp2	transition protein 2	0.014
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.014
Esr2	estrogen receptor 2 (ER beta)	0.014
Mmp3	matrix metallopeptidase 3	0.014
Hrh1	histamine receptor H 1	0.014
Pdk4	pyruvate dehydrogenase kinase, isozyme 4	0.014
Scn4a	sodium channel, voltage-gated, type IV, alpha subunit	0.014
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.014
Nkx6-1	NK6 homeobox 1	0.014
Slc22a2	solute carrier family 22 (organic cation transporter), member 2	0.014
Kctd13	potassium channel tetramerisation domain containing 13	0.014
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.013
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.013	Human Mouse Rat
Chrm1	cholinergic receptor, muscarinic 1	0.013
Grifin	galectin-related inter-fiber protein	0.013
Cckbr	cholecystokinin B receptor	0.013
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.013
Aqp4	aquaporin 4	0.013
Sstr1	somatostatin receptor 1	0.013
Mrgprf	MAS-related GPR, member F	0.013
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.013
Fcer2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.013
Uhmk1	U2AF homology motif (UHM) kinase 1	0.013
Cyp11b3	cytochrome P450, family 11, subfamily b, polypeptide 3	0.013
Cd79b	Cd79b molecule, immunoglobulin-associated beta	0.013
Pgc	progastricsin (pepsinogen C)	0.013
Grm4	glutamate receptor, metabotropic 4	0.013
ND4	NADH dehydrogenase subunit 4	0.013
Pitx2	paired-like homeodomain 2	0.013
Gabrr1	gamma-aminobutyric acid (GABA) receptor, rho 1	0.013
Gja6	gap junction protein, alpha 6	0.013
Syt6	synaptotagmin VI	0.013
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.012
Accn2	amiloride-sensitive cation channel 2, neuronal	0.012
Ibsp	integrin-binding sialoprotein	0.012
Necab1	N-terminal EF-hand calcium binding protein 1	0.012
Drd1a	dopamine receptor D1A	0.012
Nrl	neural retina leucine zipper	0.012
Npr3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	0.012
Clstn3	calsyntenin 3	0.012
Syt2	synaptotagmin II	0.012
Slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.012
Cd247	Cd247 molecule	0.012
Kcnq2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.012
Ngf	nerve growth factor (beta polypeptide)	0.012
Drd4	dopamine receptor D4	0.012
Psp	parotid secretory protein	0.012
Olr1523	olfactory receptor 1523	0.012
Kcnn1	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1	0.012
Adra1a	adrenergic, alpha-1A-, receptor	0.012	Rat
Pnmt	phenylethanolamine-N-methyltransferase	0.012
Gpr1	G protein-coupled receptor 1	0.012
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.011
Creb1	cAMP responsive element binding protein 1	0.011
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.011
Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform	0.011
Hpca	hippocalcin	0.011
Phyhip	phytanoyl-CoA 2-hydroxylase interacting protein	0.011
Mmp7	matrix metallopeptidase 7	0.011
Pcdhb12	protocadherin beta 12	0.011
Foxe3	forkhead box E3	0.011
Hrh4	histamine receptor H4	0.011
Gjb5	gap junction protein, beta 5	0.011
Avpr2	arginine vasopressin receptor 2	0.011
Ccr3	chemokine (C-C motif) receptor 3	0.011
Slc28a3	solute carrier family 28 (sodium-coupled nucleoside transporter), member 3	0.011
Pou3f2	POU class 3 homeobox 2	0.011
Mstn	myostatin	0.011
Nalcn	sodium leak channel, non-selective	0.011
Galr1	galanin receptor 1	0.011
Homer3	homer homolog 3 (Drosophila)	0.011
Oxtr	oxytocin receptor	0.011
Sec14l3	SEC14-like 3 (S. cerevisiae)	0.011
Olr226	olfactory receptor 226	0.011
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.011
Kcnj16	potassium inwardly-rectifying channel, subfamily J, member 16	0.011
Sidt1	SID1 transmembrane family, member 1	0.011
Lrrc15	leucine rich repeat containing 15	0.011
Gabra5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	0.011
Acrv1	acrosomal vesicle protein 1	0.011
Kcnh5	potassium voltage-gated channel, subfamily H (eag-related), member 5	0.011
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.011
Pip	prolactin induced protein	0.010
Hs3st2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2	0.010
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.010
Lifr	leukemia inhibitory factor receptor alpha	0.010
Cntn3	contactin 3 (plasmacytoma associated)	0.010
Syt9	synaptotagmin IX	0.010
Adora1	adenosine A1 receptor	0.010
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.010
Atp1a4	ATPase, Na+/K+ transporting, alpha 4 polypeptide	0.010
Map3k9	mitogen-activated protein kinase kinase kinase 9	0.010
Usp40	ubiquitin specific peptidase 40	0.010
Akr1c18	aldo-keto reductase family 1, member C18	0.010
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.010