The network for 'mature natural killer cell chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mature natural killer cell chemotaxis

The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.

Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 1.000
CCL4 chemokine (C-C motif) ligand 4 1.000
CCL2 chemokine (C-C motif) ligand 2 1.000
CCL5 chemokine (C-C motif) ligand 5 1.000
CXCL9 chemokine (C-X-C motif) ligand 9 1.000
IL8 interleukin 8 1.000
IL1B interleukin 1, beta 0.997
CXCL10 chemokine (C-X-C motif) ligand 10 0.996
CXCL2 chemokine (C-X-C motif) ligand 2 0.996
CCL8 chemokine (C-C motif) ligand 8 0.994
IL6 interleukin 6 (interferon, beta 2) 0.987
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.986
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.985
CXCL3 chemokine (C-X-C motif) ligand 3 0.977
CCL22 chemokine (C-C motif) ligand 22 0.976
DPP4 dipeptidyl-peptidase 4 0.975
CCR7 chemokine (C-C motif) receptor 7 0.969
CXCL11 chemokine (C-X-C motif) ligand 11 0.964
ICAM1 intercellular adhesion molecule 1 0.942
IDE insulin-degrading enzyme 0.924
CCL13 chemokine (C-C motif) ligand 13 0.909
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.879
CCL19 chemokine (C-C motif) ligand 19 0.862
CCL3 chemokine (C-C motif) ligand 3 0.843
TNF tumor necrosis factor 0.835
IFNG interferon, gamma 0.824
CXCL13 chemokine (C-X-C motif) ligand 13 0.808
CD83 CD83 molecule 0.806
VCAM1 vascular cell adhesion molecule 1 0.798
TRAF1 TNF receptor-associated factor 1 0.763
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.742
CCL20 chemokine (C-C motif) ligand 20 0.734
RGS1 regulator of G-protein signaling 1 0.724
CCR1 chemokine (C-C motif) receptor 1 0.703
IL7R interleukin 7 receptor 0.687
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.659
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.634
IL10 interleukin 10 0.538
CCL7 chemokine (C-C motif) ligand 7 0.498
SELE selectin E 0.493
CCR4 chemokine (C-C motif) receptor 4 0.489
CXCL5 chemokine (C-X-C motif) ligand 5 0.486
IL2RB interleukin 2 receptor, beta 0.462
BCL2A1 BCL2-related protein A1 0.454
UBD ubiquitin D 0.375
CCL11 chemokine (C-C motif) ligand 11 0.373
IL1RN interleukin 1 receptor antagonist 0.351
BIRC3 baculoviral IAP repeat containing 3 0.334
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.325
SRGN serglycin 0.304
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.279
CH25H cholesterol 25-hydroxylase 0.270
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.207
FPR3 formyl peptide receptor 3 0.192
IL2RG interleukin 2 receptor, gamma 0.185
CD69 CD69 molecule 0.177
CD40 CD40 molecule, TNF receptor superfamily member 5 0.175
DARC Duffy blood group, chemokine receptor 0.166
IDO1 indoleamine 2,3-dioxygenase 1 0.161
LAMP3 lysosomal-associated membrane protein 3 0.158
IL10RA interleukin 10 receptor, alpha 0.149
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.129
EBI3 Epstein-Barr virus induced 3 0.127
ADAMDEC1 ADAM-like, decysin 1 0.126
CCL3L3 chemokine (C-C motif) ligand 3-like 3 0.119
PLEK pleckstrin 0.118
IRF4 interferon regulatory factor 4 0.105
STAT4 signal transducer and activator of transcription 4 0.104
SLAMF8 SLAM family member 8 0.096
SOD2 superoxide dismutase 2, mitochondrial 0.094
SLAMF7 SLAM family member 7 0.091
IL18RAP interleukin 18 receptor accessory protein 0.088
IL1R2 interleukin 1 receptor, type II 0.088
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.084
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.077
IL21R interleukin 21 receptor 0.075
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.072
IL2RA interleukin 2 receptor, alpha 0.071
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.068
ARRB1 arrestin, beta 1 0.068
CXCR3 chemokine (C-X-C motif) receptor 3 0.067
XCL1 chemokine (C motif) ligand 1 0.064
CXCR6 chemokine (C-X-C motif) receptor 6 0.062
RGS16 regulator of G-protein signaling 16 0.060
CCL21 chemokine (C-C motif) ligand 21 0.056
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.049
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.048
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.047
MSC musculin 0.047
CCR3 chemokine (C-C motif) receptor 3 0.047
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.047
XCL2 chemokine (C motif) ligand 2 0.046
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.043
IL1A interleukin 1, alpha 0.041
IL3 interleukin 3 (colony-stimulating factor, multiple) 0.040
CCRL2 chemokine (C-C motif) receptor-like 2 0.039
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.036
GNLY granulysin 0.035
IL15RA interleukin 15 receptor, alpha 0.034
CSF1 colony stimulating factor 1 (macrophage) 0.034
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ccl2 chemokine (C-C motif) ligand 2 0.999
Ccl8 chemokine (C-C motif) ligand 8 0.783
Ccl7 chemokine (C-C motif) ligand 7 0.751
Ccl9 chemokine (C-C motif) ligand 9 0.651
Ccl12 chemokine (C-C motif) ligand 12 0.571
Clec4d C-type lectin domain family 4, member d 0.405
AF251705 cDNA sequence AF251705 0.364
Cxcl2 chemokine (C-X-C motif) ligand 2 0.328
Ubd ubiquitin D 0.319
Ch25h cholesterol 25-hydroxylase 0.300
Mmp12 matrix metallopeptidase 12 0.269
Folr2 folate receptor 2 (fetal) 0.234
Il1b interleukin 1 beta 0.233
C3ar1 complement component 3a receptor 1 0.218
Fcgr1 Fc receptor, IgG, high affinity I 0.212
Ccr1 chemokine (C-C motif) receptor 1 0.192
Ccl4 chemokine (C-C motif) ligand 4 0.192
Irg1 immunoresponsive gene 1 0.190
Batf basic leucine zipper transcription factor, ATF-like 0.186
Ccl22 chemokine (C-C motif) ligand 22 0.176
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.160
Itgax integrin alpha X 0.153
Il1rn interleukin 1 receptor antagonist 0.150
Msr1 macrophage scavenger receptor 1 0.133
Cxcl1 chemokine (C-X-C motif) ligand 1 0.120
Gzma granzyme A 0.115
Saa3 serum amyloid A 3 0.113
Gzmb granzyme B 0.109
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.100
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.099
Batf2 basic leucine zipper transcription factor, ATF-like 2 0.096
Cd14 CD14 antigen 0.094
Lcn2 lipocalin 2 0.090
Clec4a2 C-type lectin domain family 4, member a2 0.087
Ccl17 chemokine (C-C motif) ligand 17 0.087
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.082
Mmp3 matrix metallopeptidase 3 0.081
Cxcl9 chemokine (C-X-C motif) ligand 9 0.075
Xcl1 chemokine (C motif) ligand 1 0.074
Ctsw cathepsin W 0.072
Ms4a6c membrane-spanning 4-domains, subfamily A, member 6C 0.072
Sh2d2a SH2 domain protein 2A 0.068
Has1 hyaluronan synthase1 0.048
C1qc complement component 1, q subcomponent, C chain 0.048
Sit1 suppression inducing transmembrane adaptor 1 0.048
Sele selectin, endothelial cell 0.046
Cd7 CD7 antigen 0.046
Selp selectin, platelet 0.046
Niacr1 niacin receptor 1 0.044
AI607873 expressed sequence AI607873 0.043
Slamf8 SLAM family member 8 0.043
Lag3 lymphocyte-activation gene 3 0.042
Mmp8 matrix metallopeptidase 8 0.041
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.039
F10 coagulation factor X 0.039
Slc10a6 solute carrier family 10 (sodium/bile acid cotransporter family), member 6 0.038
Cxcl10 chemokine (C-X-C motif) ligand 10 0.038
Gdf15 growth differentiation factor 15 0.036
Gm11428 predicted gene 11428 0.036
Ifitm6 interferon induced transmembrane protein 6 0.034
Clec7a C-type lectin domain family 7, member a 0.034
Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.034
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.033
Cd3e CD3 antigen, epsilon polypeptide 0.033
Cd8a CD8 antigen, alpha chain 0.033
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.032
Ccl11 chemokine (C-C motif) ligand 11 0.031
Gzmk granzyme K 0.031
Cd209e CD209e antigen 0.031
Pdcd1 programmed cell death 1 0.031
Mmp13 matrix metallopeptidase 13 0.030
Pkp3 plakophilin 3 0.030
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.030
Slpi secretory leukocyte peptidase inhibitor 0.029
Mx2 myxovirus (influenza virus) resistance 2 0.029
Cxcl13 chemokine (C-X-C motif) ligand 13 0.029
Ccl6 chemokine (C-C motif) ligand 6 0.028
Cma1 chymase 1, mast cell 0.027
Clec4n C-type lectin domain family 4, member n 0.027
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.027
Il1a interleukin 1 alpha 0.027
Ccl3 chemokine (C-C motif) ligand 3 0.027
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 0.026
Gzmc granzyme C 0.026
Ccl5 chemokine (C-C motif) ligand 5 0.025
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.025
Bdkrb1 bradykinin receptor, beta 1 0.025
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.025
Wfdc12 WAP four-disulfide core domain 12 0.025
4921517D21Rik RIKEN cDNA 4921517D21 gene 0.024
Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.023
Nppc natriuretic peptide type C 0.023
Socs1 suppressor of cytokine signaling 1 0.023
Pdcd1lg2 programmed cell death 1 ligand 2 0.023
Nnmt nicotinamide N-methyltransferase 0.023
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.022
Cxcl5 chemokine (C-X-C motif) ligand 5 0.022
Ccr5 chemokine (C-C motif) receptor 5 0.022
Il1r2 interleukin 1 receptor, type II 0.022
Clcn1 chloride channel 1 0.021
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism