Process View
The network for 'mature natural killer cell chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
CCR5 | chemokine (C-C motif) receptor 5 | 1.000 | |
CCL4 | chemokine (C-C motif) ligand 4 | 1.000 | |
CCL2 | chemokine (C-C motif) ligand 2 | 1.000 | |
CCL5 | chemokine (C-C motif) ligand 5 | 1.000 | |
CXCL9 | chemokine (C-X-C motif) ligand 9 | 1.000 | |
IL8 | interleukin 8 | 1.000 | |
IL1B | interleukin 1, beta | 0.997 | |
CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.996 | |
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.996 | |
CCL8 | chemokine (C-C motif) ligand 8 | 0.994 | |
IL6 | interleukin 6 (interferon, beta 2) | 0.987 | |
CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.986 | |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.985 | |
CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.977 | |
CCL22 | chemokine (C-C motif) ligand 22 | 0.976 | |
DPP4 | dipeptidyl-peptidase 4 | 0.975 | |
CCR7 | chemokine (C-C motif) receptor 7 | 0.969 | |
CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.964 | |
ICAM1 | intercellular adhesion molecule 1 | 0.942 | |
IDE | insulin-degrading enzyme | 0.924 | |
CCL13 | chemokine (C-C motif) ligand 13 | 0.909 | |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.879 | |
CCL19 | chemokine (C-C motif) ligand 19 | 0.862 | |
CCL3 | chemokine (C-C motif) ligand 3 | 0.843 | |
TNF | tumor necrosis factor | 0.835 | |
IFNG | interferon, gamma | 0.824 | |
CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.808 | |
CD83 | CD83 molecule | 0.806 | |
VCAM1 | vascular cell adhesion molecule 1 | 0.798 | |
TRAF1 | TNF receptor-associated factor 1 | 0.763 | |
TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.742 | |
CCL20 | chemokine (C-C motif) ligand 20 | 0.734 | |
RGS1 | regulator of G-protein signaling 1 | 0.724 | |
CCR1 | chemokine (C-C motif) receptor 1 | 0.703 | |
IL7R | interleukin 7 receptor | 0.687 | |
MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.659 | |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.634 | |
IL10 | interleukin 10 | 0.538 | |
CCL7 | chemokine (C-C motif) ligand 7 | 0.498 | |
SELE | selectin E | 0.493 | |
CCR4 | chemokine (C-C motif) receptor 4 | 0.489 | |
CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.486 | |
IL2RB | interleukin 2 receptor, beta | 0.462 | |
BCL2A1 | BCL2-related protein A1 | 0.454 | |
UBD | ubiquitin D | 0.375 | |
CCL11 | chemokine (C-C motif) ligand 11 | 0.373 | |
IL1RN | interleukin 1 receptor antagonist | 0.351 | |
BIRC3 | baculoviral IAP repeat containing 3 | 0.334 | |
CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.325 | |
SRGN | serglycin | 0.304 | |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.279 | |
CH25H | cholesterol 25-hydroxylase | 0.270 | |
GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.207 | |
FPR3 | formyl peptide receptor 3 | 0.192 | |
IL2RG | interleukin 2 receptor, gamma | 0.185 | |
CD69 | CD69 molecule | 0.177 | |
CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.175 | |
DARC | Duffy blood group, chemokine receptor | 0.166 | |
IDO1 | indoleamine 2,3-dioxygenase 1 | 0.161 | |
LAMP3 | lysosomal-associated membrane protein 3 | 0.158 | |
IL10RA | interleukin 10 receptor, alpha | 0.149 | |
MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.129 | |
EBI3 | Epstein-Barr virus induced 3 | 0.127 | |
ADAMDEC1 | ADAM-like, decysin 1 | 0.126 | |
CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.119 | |
PLEK | pleckstrin | 0.118 | |
IRF4 | interferon regulatory factor 4 | 0.105 | |
STAT4 | signal transducer and activator of transcription 4 | 0.104 | |
SLAMF8 | SLAM family member 8 | 0.096 | |
SOD2 | superoxide dismutase 2, mitochondrial | 0.094 | |
SLAMF7 | SLAM family member 7 | 0.091 | |
IL18RAP | interleukin 18 receptor accessory protein | 0.088 | |
IL1R2 | interleukin 1 receptor, type II | 0.088 | |
AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.084 | |
TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.077 | |
IL21R | interleukin 21 receptor | 0.075 | |
IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.072 | |
IL2RA | interleukin 2 receptor, alpha | 0.071 | |
OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.068 | |
ARRB1 | arrestin, beta 1 | 0.068 | |
CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.067 | |
XCL1 | chemokine (C motif) ligand 1 | 0.064 | |
CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.062 | |
RGS16 | regulator of G-protein signaling 16 | 0.060 | |
CCL21 | chemokine (C-C motif) ligand 21 | 0.056 | |
KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.049 | |
KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.048 | |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.047 | |
MSC | musculin | 0.047 | |
CCR3 | chemokine (C-C motif) receptor 3 | 0.047 | |
LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.047 | |
XCL2 | chemokine (C motif) ligand 2 | 0.046 | |
HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.043 | |
IL1A | interleukin 1, alpha | 0.041 | |
IL3 | interleukin 3 (colony-stimulating factor, multiple) | 0.040 | |
CCRL2 | chemokine (C-C motif) receptor-like 2 | 0.039 | |
PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.036 | |
GNLY | granulysin | 0.035 | |
IL15RA | interleukin 15 receptor, alpha | 0.034 | |
CSF1 | colony stimulating factor 1 (macrophage) | 0.034 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Ccl2 | chemokine (C-C motif) ligand 2 | 0.999 | |
Ccl8 | chemokine (C-C motif) ligand 8 | 0.783 | |
Ccl7 | chemokine (C-C motif) ligand 7 | 0.751 | |
Ccl9 | chemokine (C-C motif) ligand 9 | 0.651 | |
Ccl12 | chemokine (C-C motif) ligand 12 | 0.571 | |
Clec4d | C-type lectin domain family 4, member d | 0.405 | |
AF251705 | cDNA sequence AF251705 | 0.364 | |
Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.328 | |
Ubd | ubiquitin D | 0.319 | |
Ch25h | cholesterol 25-hydroxylase | 0.300 | |
Mmp12 | matrix metallopeptidase 12 | 0.269 | |
Folr2 | folate receptor 2 (fetal) | 0.234 | |
Il1b | interleukin 1 beta | 0.233 | |
C3ar1 | complement component 3a receptor 1 | 0.218 | |
Fcgr1 | Fc receptor, IgG, high affinity I | 0.212 | |
Ccr1 | chemokine (C-C motif) receptor 1 | 0.192 | |
Ccl4 | chemokine (C-C motif) ligand 4 | 0.192 | |
Irg1 | immunoresponsive gene 1 | 0.190 | |
Batf | basic leucine zipper transcription factor, ATF-like | 0.186 | |
Ccl22 | chemokine (C-C motif) ligand 22 | 0.176 | |
Serpina3n | serine (or cysteine) peptidase inhibitor, clade A, member 3N | 0.160 | |
Itgax | integrin alpha X | 0.153 | |
Il1rn | interleukin 1 receptor antagonist | 0.150 | |
Msr1 | macrophage scavenger receptor 1 | 0.133 | |
Cxcl1 | chemokine (C-X-C motif) ligand 1 | 0.120 | |
Gzma | granzyme A | 0.115 | |
Saa3 | serum amyloid A 3 | 0.113 | |
Gzmb | granzyme B | 0.109 | |
Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.100 | |
Csf2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.099 | |
Batf2 | basic leucine zipper transcription factor, ATF-like 2 | 0.096 | |
Cd14 | CD14 antigen | 0.094 | |
Lcn2 | lipocalin 2 | 0.090 | |
Clec4a2 | C-type lectin domain family 4, member a2 | 0.087 | |
Ccl17 | chemokine (C-C motif) ligand 17 | 0.087 | |
Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.082 | |
Mmp3 | matrix metallopeptidase 3 | 0.081 | |
Cxcl9 | chemokine (C-X-C motif) ligand 9 | 0.075 | |
Xcl1 | chemokine (C motif) ligand 1 | 0.074 | |
Ctsw | cathepsin W | 0.072 | |
Ms4a6c | membrane-spanning 4-domains, subfamily A, member 6C | 0.072 | |
Sh2d2a | SH2 domain protein 2A | 0.068 | |
Has1 | hyaluronan synthase1 | 0.048 | |
C1qc | complement component 1, q subcomponent, C chain | 0.048 | |
Sit1 | suppression inducing transmembrane adaptor 1 | 0.048 | |
Sele | selectin, endothelial cell | 0.046 | |
Cd7 | CD7 antigen | 0.046 | |
Selp | selectin, platelet | 0.046 | |
Niacr1 | niacin receptor 1 | 0.044 | |
AI607873 | expressed sequence AI607873 | 0.043 | |
Slamf8 | SLAM family member 8 | 0.043 | |
Lag3 | lymphocyte-activation gene 3 | 0.042 | |
Mmp8 | matrix metallopeptidase 8 | 0.041 | |
Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.039 | |
F10 | coagulation factor X | 0.039 | |
Slc10a6 | solute carrier family 10 (sodium/bile acid cotransporter family), member 6 | 0.038 | |
Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.038 | |
Gdf15 | growth differentiation factor 15 | 0.036 | |
Gm11428 | predicted gene 11428 | 0.036 | |
Ifitm6 | interferon induced transmembrane protein 6 | 0.034 | |
Clec7a | C-type lectin domain family 7, member a | 0.034 | |
Lilrb3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.034 | |
Lilrb4 | leukocyte immunoglobulin-like receptor, subfamily B, member 4 | 0.033 | |
Cd3e | CD3 antigen, epsilon polypeptide | 0.033 | |
Cd8a | CD8 antigen, alpha chain | 0.033 | |
Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.032 | |
Ccl11 | chemokine (C-C motif) ligand 11 | 0.031 | |
Gzmk | granzyme K | 0.031 | |
Cd209e | CD209e antigen | 0.031 | |
Pdcd1 | programmed cell death 1 | 0.031 | |
Mmp13 | matrix metallopeptidase 13 | 0.030 | |
Pkp3 | plakophilin 3 | 0.030 | |
Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.030 | |
Slpi | secretory leukocyte peptidase inhibitor | 0.029 | |
Mx2 | myxovirus (influenza virus) resistance 2 | 0.029 | |
Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.029 | |
Ccl6 | chemokine (C-C motif) ligand 6 | 0.028 | |
Cma1 | chymase 1, mast cell | 0.027 | |
Clec4n | C-type lectin domain family 4, member n | 0.027 | |
Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.027 | |
Il1a | interleukin 1 alpha | 0.027 | |
Ccl3 | chemokine (C-C motif) ligand 3 | 0.027 | |
H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | 0.026 | |
Gzmc | granzyme C | 0.026 | |
Ccl5 | chemokine (C-C motif) ligand 5 | 0.025 | |
Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.025 | |
Bdkrb1 | bradykinin receptor, beta 1 | 0.025 | |
Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.025 | |
Wfdc12 | WAP four-disulfide core domain 12 | 0.025 | |
4921517D21Rik | RIKEN cDNA 4921517D21 gene | 0.024 | |
Slc11a1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.023 | |
Nppc | natriuretic peptide type C | 0.023 | |
Socs1 | suppressor of cytokine signaling 1 | 0.023 | |
Pdcd1lg2 | programmed cell death 1 ligand 2 | 0.023 | |
Nnmt | nicotinamide N-methyltransferase | 0.023 | |
Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.022 | |
Cxcl5 | chemokine (C-X-C motif) ligand 5 | 0.022 | |
Ccr5 | chemokine (C-C motif) receptor 5 | 0.022 | |
Il1r2 | interleukin 1 receptor, type II | 0.022 | |
Clcn1 | chloride channel 1 | 0.021 |