IMP
Process View
The network for 'negative regulation of chemokine mediated signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of chemokine mediated signaling pathway
Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CCR5 | chemokine (C-C motif) receptor 5 | 1.000 | |
| IL8 | interleukin 8 | 0.993 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.973 | |
| IL1B | interleukin 1, beta | 0.972 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.968 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.955 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.904 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.880 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.858 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.851 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.843 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.711 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.692 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.602 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.532 | |
| IDE | insulin-degrading enzyme | 0.522 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.313 | |
| GNLY | granulysin | 0.293 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.268 | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.263 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.238 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.220 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.216 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.190 | |
| CCL3 | chemokine (C-C motif) ligand 3 | 0.190 | |
| IFNG | interferon, gamma | 0.183 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.139 | |
| IL2RB | interleukin 2 receptor, beta | 0.132 | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.131 | |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.124 | |
| VCAM1 | vascular cell adhesion molecule 1 | 0.122 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.119 | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.117 | |
| CD83 | CD83 molecule | 0.117 | |
| CPE | carboxypeptidase E | 0.110 | |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.110 | |
| RGS1 | regulator of G-protein signaling 1 | 0.103 | |
| CCL7 | chemokine (C-C motif) ligand 7 | 0.098 | |
| IL10 | interleukin 10 | 0.091 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.075 | |
| SELE | selectin E | 0.067 | |
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.058 | |
| IL7R | interleukin 7 receptor | 0.057 | |
| BCL2A1 | BCL2-related protein A1 | 0.052 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.049 | |
| TNF | tumor necrosis factor | 0.047 | |
| UBD | ubiquitin D | 0.042 | |
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.041 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.039 | |
| DARC | Duffy blood group, chemokine receptor | 0.037 | |
| IL1RN | interleukin 1 receptor antagonist | 0.033 | |
| CD163 | CD163 molecule | 0.033 | |
| CH25H | cholesterol 25-hydroxylase | 0.032 | |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.032 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.029 | |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.029 | |
| SRGN | serglycin | 0.029 | |
| CD69 | CD69 molecule | 0.026 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.026 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.025 | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.025 | |
| IL2RG | interleukin 2 receptor, gamma | 0.023 | |
| SLAMF7 | SLAM family member 7 | 0.022 | |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.022 | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.022 | |
| STAT4 | signal transducer and activator of transcription 4 | 0.021 | |
| IL10RA | interleukin 10 receptor, alpha | 0.020 | |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.019 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.019 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.018 | |
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.018 | |
| FPR3 | formyl peptide receptor 3 | 0.018 | |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.016 | |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.016 | |
| NKG7 | natural killer cell group 7 sequence | 0.016 | |
| DPT | dermatopontin | 0.014 | |
| ARRB1 | arrestin, beta 1 | 0.014 | |
| INHBA | inhibin, beta A | 0.013 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.013 | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.013 | |
| IL32 | interleukin 32 | 0.013 | |
| IL18R1 | interleukin 18 receptor 1 | 0.012 | |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.012 | |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.012 | |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.012 | |
| IL2RA | interleukin 2 receptor, alpha | 0.011 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.011 | |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.011 | |
| XCL2 | chemokine (C motif) ligand 2 | 0.011 | |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) | 0.010 | |
| SLAMF8 | SLAM family member 8 | 0.010 |
