IMP
Process View
The network for 'positive regulation of fibrinolysis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of fibrinolysis
Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1.000 | |
| PLAUR | plasminogen activator, urokinase receptor | 1.000 | |
| KNG1 | kininogen 1 | 0.992 | |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.990 | |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.848 | |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.816 | |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.620 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.413 | |
| PLG | plasminogen | 0.395 | |
| C8A | complement component 8, alpha polypeptide | 0.338 | |
| C8B | complement component 8, beta polypeptide | 0.311 | |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 0.301 | |
| VTN | vitronectin | 0.289 | |
| CPN1 | carboxypeptidase N, polypeptide 1 | 0.238 | |
| ORM1 | orosomucoid 1 | 0.209 | |
| MASP2 | mannan-binding lectin serine peptidase 2 | 0.197 | |
| FGB | fibrinogen beta chain | 0.194 | |
| GCGR | glucagon receptor | 0.162 | |
| LPA | lipoprotein, Lp(a) | 0.149 | |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.146 | |
| SPP2 | secreted phosphoprotein 2, 24kDa | 0.145 | |
| HPX | hemopexin | 0.138 | |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit | 0.130 | |
| SAA4 | serum amyloid A4, constitutive | 0.111 | |
| SPHK1 | sphingosine kinase 1 | 0.109 | |
| TNC | tenascin C | 0.107 | |
| IL8 | interleukin 8 | 0.103 | |
| HRG | histidine-rich glycoprotein | 0.102 | |
| APOB | apolipoprotein B (including Ag(x) antigen) | 0.099 | |
| APOC3 | apolipoprotein C-III | 0.097 | |
| RDH16 | retinol dehydrogenase 16 (all-trans) | 0.095 | |
| TAT | tyrosine aminotransferase | 0.093 | |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 | 0.091 | |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.091 | |
| F2 | coagulation factor II (thrombin) | 0.091 | |
| ADH6 | alcohol dehydrogenase 6 (class V) | 0.084 | |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.081 | |
| APCS | amyloid P component, serum | 0.079 | |
| TFR2 | transferrin receptor 2 | 0.077 | |
| GCKR | glucokinase (hexokinase 4) regulator | 0.076 | |
| C8G | complement component 8, gamma polypeptide | 0.076 | |
| CRP | C-reactive protein, pentraxin-related | 0.076 | |
| AMT | aminomethyltransferase | 0.068 | |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 | 0.066 | |
| C6 | complement component 6 | 0.065 | |
| PROZ | protein Z, vitamin K-dependent plasma glycoprotein | 0.063 | |
| PRODH2 | proline dehydrogenase (oxidase) 2 | 0.059 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.054 | |
| ALDOB | aldolase B, fructose-bisphosphate | 0.053 | |
| C4BPB | complement component 4 binding protein, beta | 0.053 | |
| ITIH4 | inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) | 0.053 | |
| C9 | complement component 9 | 0.052 | |
| LIPC | lipase, hepatic | 0.052 | |
| FOSL1 | FOS-like antigen 1 | 0.052 | |
| LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.051 | |
| EMP1 | epithelial membrane protein 1 | 0.050 | |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 0.050 | |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 | 0.048 | |
| APOF | apolipoprotein F | 0.048 | |
| THBS1 | thrombospondin 1 | 0.046 | |
| CTGF | connective tissue growth factor | 0.045 | |
| AFM | afamin | 0.044 | |
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.044 | |
| INHBA | inhibin, beta A | 0.042 | |
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.041 | |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) | 0.040 | |
| COL4A1 | collagen, type IV, alpha 1 | 0.039 | |
| F10 | coagulation factor X | 0.039 | |
| AGXT | alanine-glyoxylate aminotransferase | 0.038 | |
| BHMT | betaine--homocysteine S-methyltransferase | 0.038 | |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.037 | |
| FTCD | formiminotransferase cyclodeaminase | 0.035 | |
| CPB2 | carboxypeptidase B2 (plasma) | 0.035 | |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 0.034 | |
| SLC38A3 | solute carrier family 38, member 3 | 0.033 | |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.033 | |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.033 | |
| ITIH2 | inter-alpha (globulin) inhibitor H2 | 0.032 | |
| ITIH1 | inter-alpha (globulin) inhibitor H1 | 0.032 | |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.032 | |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.032 | |
| AHSG | alpha-2-HS-glycoprotein | 0.031 | |
| OSMR | oncostatin M receptor | 0.030 | |
| PDGFC | platelet derived growth factor C | 0.030 | |
| ITIH3 | inter-alpha (globulin) inhibitor H3 | 0.030 | |
| HAO1 | hydroxyacid oxidase (glycolate oxidase) 1 | 0.028 | |
| KLKB1 | kallikrein B, plasma (Fletcher factor) 1 | 0.027 | |
| PXDN | peroxidasin homolog (Drosophila) | 0.025 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.023 | |
| FGA | fibrinogen alpha chain | 0.023 | |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 0.023 | |
| ARG1 | arginase, liver | 0.022 | |
| F11 | coagulation factor XI | 0.022 | |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 | 0.022 | |
| FGG | fibrinogen gamma chain | 0.022 | |
| SERPINA10 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | 0.022 | |
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.022 | |
| AKR1C4 | aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) | 0.021 | |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.021 | |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 | 0.021 |
