The network for 'regulation of mhc class ii biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of mhc class ii biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.

Homo sapiens
Name Description Probability Func Analog Organism
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.988
CXCL10 chemokine (C-X-C motif) ligand 10 0.937
CXCL11 chemokine (C-X-C motif) ligand 11 0.887
CXCL5 chemokine (C-X-C motif) ligand 5 0.715
CXCL2 chemokine (C-X-C motif) ligand 2 0.674
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.668
IL8 interleukin 8 0.653
IL4R interleukin 4 receptor 0.406
PF4 platelet factor 4 0.377
DPP4 dipeptidyl-peptidase 4 0.321
IL2RG interleukin 2 receptor, gamma 0.212
TICAM2 toll-like receptor adaptor molecule 2 0.184
LY96 lymphocyte antigen 96 0.156
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.156
HBA2 hemoglobin, alpha 2 0.150
CCL8 chemokine (C-C motif) ligand 8 0.146
MPO myeloperoxidase 0.100
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 0.085
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.082
PF4V1 platelet factor 4 variant 1 0.076
S100A12 S100 calcium binding protein A12 0.074
CCL20 chemokine (C-C motif) ligand 20 0.056
CXCR3 chemokine (C-X-C motif) receptor 3 0.052
IDO1 indoleamine 2,3-dioxygenase 1 0.051
TFEC transcription factor EC 0.045
BPI bactericidal/permeability-increasing protein 0.042
GFI1 growth factor independent 1 transcription repressor 0.042
NFE2 nuclear factor (erythroid-derived 2), 45kDa 0.036
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.035
CCL7 chemokine (C-C motif) ligand 7 0.034
HBD hemoglobin, delta 0.032
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.031
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.030
LCN2 lipocalin 2 0.028
CXCL13 chemokine (C-X-C motif) ligand 13 0.028
APOBR apolipoprotein B receptor 0.028
PLEK pleckstrin 0.026
IFNG interferon, gamma 0.026
MOBKL2B MOB1, Mps One Binder kinase activator-like 2B (yeast) 0.025
APOL1 apolipoprotein L, 1 0.025
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.025
SKI v-ski sarcoma viral oncogene homolog (avian) 0.024
CXCL3 chemokine (C-X-C motif) ligand 3 0.023
LAMP3 lysosomal-associated membrane protein 3 0.023
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.023
HBB hemoglobin, beta 0.022
SELE selectin E 0.022
IL15RA interleukin 15 receptor, alpha 0.022
UBD ubiquitin D 0.022
CTSG cathepsin G 0.022
IL6 interleukin 6 (interferon, beta 2) 0.021
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.020
EFNA1 ephrin-A1 0.020
APOL3 apolipoprotein L, 3 0.020
RSAD2 radical S-adenosyl methionine domain containing 2 0.019
CCL2 chemokine (C-C motif) ligand 2 0.019
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.019
CLEC4G C-type lectin domain family 4, member G 0.018
IL10 interleukin 10 0.018
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.018
GBP4 guanylate binding protein 4 0.018
GPR97 G protein-coupled receptor 97 0.018
CH25H cholesterol 25-hydroxylase 0.017
VCAM1 vascular cell adhesion molecule 1 0.017
IFI27 interferon, alpha-inducible protein 27 0.017
ALAS2 aminolevulinate, delta-, synthase 2 0.016
CLC Charcot-Leyden crystal protein 0.016
RARA retinoic acid receptor, alpha 0.016
HOXA10 homeobox A10 0.016
CXCL9 chemokine (C-X-C motif) ligand 9 0.016
KLF1 Kruppel-like factor 1 (erythroid) 0.016
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.016
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.016
RNASE3 ribonuclease, RNase A family, 3 0.015
RPS27 ribosomal protein S27 0.015
DEFA4 defensin, alpha 4, corticostatin 0.015
GP5 glycoprotein V (platelet) 0.015
BIRC3 baculoviral IAP repeat containing 3 0.015
CAMP cathelicidin antimicrobial peptide 0.015
IFI44L interferon-induced protein 44-like 0.014
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.014
POU2F2 POU class 2 homeobox 2 0.014
AZU1 azurocidin 1 0.014
IL11 interleukin 11 0.014
HP haptoglobin 0.014
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.014
EP300 E1A binding protein p300 0.013
MMP7 matrix metallopeptidase 7 (matrilysin, uterine) 0.013
ALB albumin 0.013
HIPK2 homeodomain interacting protein kinase 2 0.013
NRGN neurogranin (protein kinase C substrate, RC3) 0.013
IL15 interleukin 15 0.013
VPREB1 pre-B lymphocyte 1 0.012
MMP8 matrix metallopeptidase 8 (neutrophil collagenase) 0.012
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.012
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.012
MESDC2 mesoderm development candidate 2 0.012
OASL 2'-5'-oligoadenylate synthetase-like 0.011
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.011
S100A8 S100 calcium binding protein A8 0.011
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Il10 interleukin 10 0.997
Tlr4 toll-like receptor 4 0.985
Ifng interferon gamma 0.948
Tnf tumor necrosis factor 0.930
Ccr2 chemokine (C-C motif) receptor 2 0.809
Lyz2 lysozyme 2 0.758
Mmp9 matrix metallopeptidase 9 0.727
Ccl2 chemokine (C-C motif) ligand 2 0.302
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.269
Nos2 nitric oxide synthase 2, inducible 0.265
Myd88 myeloid differentiation primary response gene 88 0.200
Spp1 secreted phosphoprotein 1 0.184
Tlr2 toll-like receptor 2 0.165
Rag1 recombination activating gene 1 0.110
Cd44 CD44 antigen 0.105
Il4 interleukin 4 0.104
Il6 interleukin 6 0.068
Btk Bruton agammaglobulinemia tyrosine kinase 0.066
Igh immunoglobulin heavy chain complex 0.045
Ccr1 chemokine (C-C motif) receptor 1 0.045
Pparg peroxisome proliferator activated receptor gamma 0.043
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.035
Pou2af1 POU domain, class 2, associating factor 1 0.023
Ccr5 chemokine (C-C motif) receptor 5 0.020
Tgfb1 transforming growth factor, beta 1 0.020
Il1r1 interleukin 1 receptor, type I 0.019
Cd40 CD40 antigen 0.018
Fas Fas (TNF receptor superfamily member 6) 0.016
Cd14 CD14 antigen 0.016
Prkdc protein kinase, DNA activated, catalytic polypeptide 0.013
Vdr vitamin D receptor 0.013
Nlrp3 NLR family, pyrin domain containing 3 0.013
Il2 interleukin 2 0.013
Tcra T-cell receptor alpha chain 0.013
Lepr leptin receptor 0.013
Ticam1 toll-like receptor adaptor molecule 1 0.013
Cd28 CD28 antigen 0.013
Ldlr low density lipoprotein receptor 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism