The network for 'phagocytosis recognition' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

phagocytosis recognition

The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.

Homo sapiens
Name Description Probability Func Analog Organism
SYK spleen tyrosine kinase 0.997
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.994
KLRC3 killer cell lectin-like receptor subfamily C, member 3 0.917
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.877
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.809
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.789
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.752
LCK lymphocyte-specific protein tyrosine kinase 0.733
GZMK granzyme K (granzyme 3; tryptase II) 0.696
TYROBP TYRO protein tyrosine kinase binding protein 0.654
ZCCHC17 zinc finger, CCHC domain containing 17 0.640
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.582
BRD4 bromodomain containing 4 0.562
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.561
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.493
ITK IL2-inducible T-cell kinase 0.490
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.459
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.452
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.445
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.442
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.427
PRF1 perforin 1 (pore forming protein) 0.426
CD33 CD33 molecule 0.412
PILRA paired immunoglobin-like type 2 receptor alpha 0.399
CLEC4A C-type lectin domain family 4, member A 0.379
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.370
CD163 CD163 molecule 0.337
PECAM1 platelet/endothelial cell adhesion molecule 0.281
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.273
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.266
IFNG interferon, gamma 0.246
GPR65 G protein-coupled receptor 65 0.243
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.227
GNLY granulysin 0.227
PRPF38A PRP38 pre-mRNA processing factor 38 (yeast) domain containing A 0.222
EPOR erythropoietin receptor 0.216
CCR5 chemokine (C-C motif) receptor 5 0.209
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.206
UBASH3B ubiquitin associated and SH3 domain containing B 0.167
FASLG Fas ligand (TNF superfamily, member 6) 0.149
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.144
CCR1 chemokine (C-C motif) receptor 1 0.129
KLRC4 killer cell lectin-like receptor subfamily C, member 4 0.125
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.121
CCR2 chemokine (C-C motif) receptor 2 0.117
CD84 CD84 molecule 0.109
FGL2 fibrinogen-like 2 0.109
GPR171 G protein-coupled receptor 171 0.105
CXCR6 chemokine (C-X-C motif) receptor 6 0.104
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.096
CCL4 chemokine (C-C motif) ligand 4 0.096
F13A1 coagulation factor XIII, A1 polypeptide 0.094
CD160 CD160 molecule 0.094
CD2 CD2 molecule 0.091
IGSF6 immunoglobulin superfamily, member 6 0.088
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.085
LEPROTL1 leptin receptor overlapping transcript-like 1 0.085
CYBB cytochrome b-245, beta polypeptide 0.083
CXCL9 chemokine (C-X-C motif) ligand 9 0.082
GIMAP4 GTPase, IMAP family member 4 0.071
SH3BP2 SH3-domain binding protein 2 0.070
CD53 CD53 molecule 0.066
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.065
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.063
XCL2 chemokine (C motif) ligand 2 0.063
CD93 CD93 molecule 0.062
EMR1 egf-like module containing, mucin-like, hormone receptor-like 1 0.062
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.062
NKG7 natural killer cell group 7 sequence 0.059
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.058
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.055
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.055
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 0.055
FYB FYN binding protein 0.055
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.054
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.050
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.050
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.046
IL18RAP interleukin 18 receptor accessory protein 0.046
CLEC5A C-type lectin domain family 5, member A 0.046
TLR2 toll-like receptor 2 0.046
VSIG4 V-set and immunoglobulin domain containing 4 0.046
ADORA3 adenosine A3 receptor 0.044
CD1C CD1c molecule 0.042
TFEC transcription factor EC 0.042
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.042
FPR3 formyl peptide receptor 3 0.042
MSR1 macrophage scavenger receptor 1 0.041
IL4R interleukin 4 receptor 0.041
CD96 CD96 molecule 0.041
CSF1R colony stimulating factor 1 receptor 0.040
SIGLEC7 sialic acid binding Ig-like lectin 7 0.038
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 0.038
PYHIN1 pyrin and HIN domain family, member 1 0.038
GRAP2 GRB2-related adaptor protein 2 0.038
CD226 CD226 molecule 0.037
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.036
SRSF4 serine/arginine-rich splicing factor 4 0.035
MNDA myeloid cell nuclear differentiation antigen 0.035
CD28 CD28 molecule 0.034
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
drpr draper 0.274
CG9990 CG9990 gene product from transcript CG9990-RA 0.101
Lsd-2 Lipid storage droplet-2 0.096
Npc2g Niemann-Pick type C-2g 0.091
MED4 Mediator complex subunit 4 0.063
CG3305 CG3305 gene product from transcript CG3305-RA 0.054
inaD inactivation no afterpotential D 0.049
CG11073 CG11073 gene product from transcript CG11073-RB 0.043
plexB plexin B 0.040
CG4822 CG4822 gene product from transcript CG4822-RB 0.038
CG14526 CG14526 gene product from transcript CG14526-RB 0.035
trpl trp-like 0.034
CG10743 CG10743 gene product from transcript CG10743-RB 0.030
CG6490 CG6490 gene product from transcript CG6490-RB 0.029
CG8602 CG8602 gene product from transcript CG8602-RA 0.027
CG3164 CG3164 gene product from transcript CG3164-RA 0.025
Best1 Bestrophin 1 0.024
CG18249 CG18249 gene product from transcript CG18249-RB 0.022
CG15828 CG15828 gene product from transcript CG15828-RC 0.021
CG13784 CG13784 gene product from transcript CG13784-RC 0.021
CG15917 CG15917 gene product from transcript CG15917-RA 0.020
Fim Fimbrin 0.020
CG9628 CG9628 gene product from transcript CG9628-RA 0.019
CG31778 CG31778 gene product from transcript CG31778-RA 0.019
CG5853 CG5853 gene product from transcript CG5853-RA 0.019
Glt Glutactin 0.018
nimC4 nimrod C4 0.018
CG5004 CG5004 gene product from transcript CG5004-RA 0.018
He Hemese 0.017
CG14933 CG14933 gene product from transcript CG14933-RA 0.016
CG5493 CG5493 gene product from transcript CG5493-RA 0.015
Rh6 Rhodopsin 6 0.015
GNBP3 Gram-negative bacteria binding protein 3 0.015
CG7997 CG7997 gene product from transcript CG7997-RB 0.015
CG6051 CG6051 gene product from transcript CG6051-RB 0.015
CG10026 CG10026 gene product from transcript CG10026-RA 0.014
CG13526 CG13526 gene product from transcript CG13526-RA 0.014
CG4607 CG4607 gene product from transcript CG4607-RA 0.014
kat-60L1 katanin p60-like 1 0.014
CG4306 CG4306 gene product from transcript CG4306-RA 0.013
psh persephone 0.013
tadr torn and diminished rhabdomeres 0.013
CG13636 CG13636 gene product from transcript CG13636-RB 0.012
Atet ABC transporter expressed in trachea 0.012
CG32091 CG32091 gene product from transcript CG32091-RB 0.012
wtrw CG31284 gene product from transcript CG31284-RB 0.012
alpha-Est2 alpha-Esterase-2 0.012
CG17646 CG17646 gene product from transcript CG17646-RB 0.012
Edem2 CG5682 gene product from transcript CG5682-RA 0.012
Arr2 Arrestin 2 0.011
CG14216 CG14216 gene product from transcript CG14216-RA 0.011
CG7675 CG7675 gene product from transcript CG7675-RC 0.011
Dhap-at Dihydroxyacetone phosphate acyltransferase 0.011
CG8317 CG8317 gene product from transcript CG8317-RA 0.011
CG5326 CG5326 gene product from transcript CG5326-RA 0.011
Acer Angiotensin-converting enzyme-related 0.011
CG9444 CG9444 gene product from transcript CG9444-RA 0.011
CG16926 CG16926 gene product from transcript CG16926-RA 0.011
CG11147 CG11147 gene product from transcript CG11147-RA 0.011
mthl1 methuselah-like 1 0.010
CG9801 CG9801 gene product from transcript CG9801-RC 0.010
Gli Gliotactin 0.010
prtp pretaporter 0.010
CG33970 CG33970 gene product from transcript CG33970-RA 0.010
wnd wallenda 0.010
CG7852 CG7852 gene product from transcript CG7852-RA 0.010
CG6053 CG6053 gene product from transcript CG6053-RB 0.010
Neu3 CG7649 gene product from transcript CG7649-RC 0.010
CG8654 CG8654 gene product from transcript CG8654-RA 0.010
Bmcp CG7314 gene product from transcript CG7314-RB 0.010
CG11880 CG11880 gene product from transcript CG11880-RA 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.421
Clec4d C-type lectin domain family 4, member d 0.333
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.285
Ncr1 natural cytotoxicity triggering receptor 1 0.144
Clec4a2 C-type lectin domain family 4, member a2 0.124
Clec4e C-type lectin domain family 4, member e 0.119
Msr1 macrophage scavenger receptor 1 0.107
Clec4n C-type lectin domain family 4, member n 0.094
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.075
Fpr2 formyl peptide receptor 2 0.064
Ccr1 chemokine (C-C motif) receptor 1 0.061
Klra2 killer cell lectin-like receptor, subfamily A, member 2 0.060
Plxnd1 plexin D1 0.057
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.048
Gzma granzyme A 0.046
Cr2 complement receptor 2 0.040
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.038
C3ar1 complement component 3a receptor 1 0.038
Cd209b CD209b antigen 0.036
Fcrla Fc receptor-like A 0.035
Fpr1 formyl peptide receptor 1 0.034
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.034
Ms4a6d membrane-spanning 4-domains, subfamily A, member 6D 0.034
Ms4a1 membrane-spanning 4-domains, subfamily A, member 1 0.033
Ccl6 chemokine (C-C motif) ligand 6 0.033
Klrc1 killer cell lectin-like receptor subfamily C, member 1 0.032
Il18rap interleukin 18 receptor accessory protein 0.030
Cybb cytochrome b-245, beta polypeptide 0.029
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.029
Pilrb1 paired immunoglobin-like type 2 receptor beta 1 0.029
Ccr5 chemokine (C-C motif) receptor 5 0.026
Pf4 platelet factor 4 0.026
AF251705 cDNA sequence AF251705 0.025
Cd209d CD209d antigen 0.024
Lair1 leukocyte-associated Ig-like receptor 1 0.024
Blk B lymphoid kinase 0.024
Ccl9 chemokine (C-C motif) ligand 9 0.023
Cd209a CD209a antigen 0.022
Clec7a C-type lectin domain family 7, member a 0.022
Emr4 EGF-like module containing, mucin-like, hormone receptor-like sequence 4 0.021
Mmp8 matrix metallopeptidase 8 0.021
Il1b interleukin 1 beta 0.020
Igk immunoglobulin kappa chain complex 0.019
Pilra paired immunoglobin-like type 2 receptor alpha 0.019
Mefv Mediterranean fever 0.018
Ccl24 chemokine (C-C motif) ligand 24 0.018
Chi3l3 chitinase 3-like 3 0.017
Mpeg1 macrophage expressed gene 1 0.017
Clec4b1 C-type lectin domain family 4, member b1 0.017
Cd5l CD5 antigen-like 0.016
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.016
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.016
Fcgr4 Fc receptor, IgG, low affinity IV 0.016
Aoah acyloxyacyl hydrolase 0.015
Igsf6 immunoglobulin superfamily, member 6 0.015
Tcfec transcription factor EC 0.014
Mgl2 macrophage galactose N-acetyl-galactosamine specific lectin 2 0.014
Ccr3 chemokine (C-C motif) receptor 3 0.014
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.014
Cfh complement component factor h 0.014
Tlr8 toll-like receptor 8 0.013
Mmp12 matrix metallopeptidase 12 0.013
Rgs18 regulator of G-protein signaling 18 0.013
Cpa3 carboxypeptidase A3, mast cell 0.013
Klra17 killer cell lectin-like receptor, subfamily A, member 17 0.013
Mrc1 mannose receptor, C type 1 0.013
Siglece sialic acid binding Ig-like lectin E 0.012
Cd300ld CD300 molecule-like family member d 0.012
F13a1 coagulation factor XIII, A1 subunit 0.012
Cd14 CD14 antigen 0.012
Ms4a7 membrane-spanning 4-domains, subfamily A, member 7 0.012
Cd33 CD33 antigen 0.012
Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.012
Pax5 paired box gene 5 0.012
Klrb1c killer cell lectin-like receptor subfamily B member 1C 0.012
Flt3 FMS-like tyrosine kinase 3 0.012
Klra7 killer cell lectin-like receptor, subfamily A, member 7 0.012
Trem3 triggering receptor expressed on myeloid cells 3 0.012
Klra5 killer cell lectin-like receptor, subfamily A, member 5 0.012
Sirpb1a signal-regulatory protein beta 1A 0.011
Apoe apolipoprotein E 0.011
Gda guanine deaminase 0.011
Cma1 chymase 1, mast cell 0.011
Slamf7 SLAM family member 7 0.011
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.011
Gzmk granzyme K 0.011
Csf1r colony stimulating factor 1 receptor 0.010
Gcet2 germinal center expressed transcript 2 0.010
Niacr1 niacin receptor 1 0.010
Igj immunoglobulin joining chain 0.010
Cd300a CD300A antigen 0.010
Igl immunoglobulin lambda chain complex 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.015
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.014
C1qa complement component 1, q subcomponent, A chain 0.013
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism