The network for 'negative regulation of cd4 positive alpha beta t cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of cd4 positive alpha beta t cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.

Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 1.000
CCL4 chemokine (C-C motif) ligand 4 1.000
IL8 interleukin 8 0.999
CCL2 chemokine (C-C motif) ligand 2 0.996
CXCL9 chemokine (C-X-C motif) ligand 9 0.996
IL1B interleukin 1, beta 0.989
CXCL2 chemokine (C-X-C motif) ligand 2 0.985
CCL8 chemokine (C-C motif) ligand 8 0.983
CXCL10 chemokine (C-X-C motif) ligand 10 0.983
CCL5 chemokine (C-C motif) ligand 5 0.974
IL6 interleukin 6 (interferon, beta 2) 0.968
CXCL3 chemokine (C-X-C motif) ligand 3 0.957
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.955
DPP4 dipeptidyl-peptidase 4 0.915
CCL13 chemokine (C-C motif) ligand 13 0.903
CXCL11 chemokine (C-X-C motif) ligand 11 0.873
ICAM1 intercellular adhesion molecule 1 0.869
CCR7 chemokine (C-C motif) receptor 7 0.866
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.860
CCL22 chemokine (C-C motif) ligand 22 0.791
CXCL13 chemokine (C-X-C motif) ligand 13 0.724
CD83 CD83 molecule 0.695
IDE insulin-degrading enzyme 0.687
RGS1 regulator of G-protein signaling 1 0.592
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.559
IFNG interferon, gamma 0.547
CCL20 chemokine (C-C motif) ligand 20 0.507
GNLY granulysin 0.503
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.446
CCL7 chemokine (C-C motif) ligand 7 0.395
CXCL5 chemokine (C-X-C motif) ligand 5 0.388
IL7R interleukin 7 receptor 0.369
CCL19 chemokine (C-C motif) ligand 19 0.347
IL10 interleukin 10 0.326
CCL11 chemokine (C-C motif) ligand 11 0.301
IL2RB interleukin 2 receptor, beta 0.299
CCR1 chemokine (C-C motif) receptor 1 0.272
VCAM1 vascular cell adhesion molecule 1 0.255
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.248
BCL2A1 BCL2-related protein A1 0.248
SELE selectin E 0.225
CCL3 chemokine (C-C motif) ligand 3 0.223
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.220
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.217
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.189
CD69 CD69 molecule 0.189
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.186
FPR3 formyl peptide receptor 3 0.184
CH25H cholesterol 25-hydroxylase 0.173
TNF tumor necrosis factor 0.170
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.168
TRAF1 TNF receptor-associated factor 1 0.156
CCR4 chemokine (C-C motif) receptor 4 0.155
EBI3 Epstein-Barr virus induced 3 0.154
BIRC3 baculoviral IAP repeat containing 3 0.146
SRGN serglycin 0.127
UBD ubiquitin D 0.117
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.116
LAMP3 lysosomal-associated membrane protein 3 0.114
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.111
IL2RG interleukin 2 receptor, gamma 0.101
DARC Duffy blood group, chemokine receptor 0.101
STAT4 signal transducer and activator of transcription 4 0.100
IL18RAP interleukin 18 receptor accessory protein 0.100
CD80 CD80 molecule 0.099
ADAMDEC1 ADAM-like, decysin 1 0.092
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.092
IL32 interleukin 32 0.091
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.087
SLAMF8 SLAM family member 8 0.081
IL10RA interleukin 10 receptor, alpha 0.077
CD40 CD40 molecule, TNF receptor superfamily member 5 0.077
IDO1 indoleamine 2,3-dioxygenase 1 0.075
ZC3H12A zinc finger CCCH-type containing 12A 0.074
SLAMF7 SLAM family member 7 0.073
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.073
ARRB1 arrestin, beta 1 0.072
CCL3L3 chemokine (C-C motif) ligand 3-like 3 0.068
SOD2 superoxide dismutase 2, mitochondrial 0.066
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.062
PLAUR plasminogen activator, urokinase receptor 0.062
CCR3 chemokine (C-C motif) receptor 3 0.061
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.060
CD2 CD2 molecule 0.059
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.056
IL1RN interleukin 1 receptor antagonist 0.053
PLEK pleckstrin 0.051
IL21R interleukin 21 receptor 0.049
INHBA inhibin, beta A 0.047
ZFYVE9 zinc finger, FYVE domain containing 9 0.046
CXCR6 chemokine (C-X-C motif) receptor 6 0.045
XCL2 chemokine (C motif) ligand 2 0.044
IL2RA interleukin 2 receptor, alpha 0.041
SLAMF1 signaling lymphocytic activation molecule family member 1 0.040
C1QA complement component 1, q subcomponent, A chain 0.040
CCRL2 chemokine (C-C motif) receptor-like 2 0.035
RGS16 regulator of G-protein signaling 16 0.034
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.032
IL1A interleukin 1, alpha 0.031
CCL17 chemokine (C-C motif) ligand 17 0.031
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism