The network for 'organelle disassembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

organelle disassembly

The disaggregation of an organelle into its constituent components.

Homo sapiens
Name Description Probability Func Analog Organism
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.625
HSPA1B heat shock 70kDa protein 1B 0.584
HSPA1A heat shock 70kDa protein 1A 0.352
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.233
MCTS1 malignant T cell amplified sequence 1 0.179
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.151
DENR density-regulated protein 0.104
PABPC1 poly(A) binding protein, cytoplasmic 1 0.060
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.058
UFD1L ubiquitin fusion degradation 1 like (yeast) 0.056
BAG1 BCL2-associated athanogene 0.049
SEPT2 septin 2 0.039
BAG3 BCL2-associated athanogene 3 0.028
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.027
TNPO1 transportin 1 0.024
UBE4B ubiquitination factor E4B (UFD2 homolog, yeast) 0.021
HSPH1 heat shock 105kDa/110kDa protein 1 0.020
SIRT2 sirtuin 2 0.019
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.017
GTSE1 G-2 and S-phase expressed 1 0.013
ETF1 eukaryotic translation termination factor 1 0.013
PRNP prion protein 0.012
TCP1 t-complex 1 0.012
KCNE3 potassium voltage-gated channel, Isk-related family, member 3 0.011
NSFL1C NSFL1 (p97) cofactor (p47) 0.010
ITSN1 intersectin 1 (SH3 domain protein) 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
rpn-1 Protein RPN-1 0.171
paa-1 Protein PAA-1 0.044
daf-21 Protein DAF-21 0.036
hsp-1 Protein HSP-1 0.032
tars-1 Protein TARS-1 0.028
tbb-1 Protein TBB-1 0.028
tsr-1 Protein TSR-1 0.025
prp-8 Protein PRP-8 0.025
acs-4 Protein ACS-4 0.023
tbb-2 Protein TBB-2 0.021
mrp-4 Protein MRP-4 0.017
T22F3.3 Protein T22F3.3 0.017
eef-1A.1 Protein EEF-1A.1 0.017
mig-15 Protein MIG-15 0.016
chc-1 Protein CHC-1 0.016
F52C9.7 Protein F52C9.7 0.016
frm-2 Protein FRM-2 0.015
cst-1 Protein CST-1 0.014
hsp-4 Protein HSP-4 0.014
cgh-1 Protein CGH-1 0.014
C30C11.4 Protein C30C11.4 0.014
F33G12.5 Protein F33G12.5 0.013
sax-3 Protein SAX-3 0.013
fkb-6 Protein FKB-6 0.013
C52E12.1 Protein C52E12.1 0.013
cct-2 Protein CCT-2 0.012
sago-2 Protein SAGO-2 0.012
ash-2 Protein ASH-2 0.012
ima-3 Protein IMA-3 0.012
T03F1.1 Protein T03F1.1 0.012
D1044.6 Protein D1044.6 0.012
pam-1 Protein PAM-1 0.012
clu-1 Protein CLU-1 0.011
rpt-3 Protein RPT-3 0.011
ztf-7 Protein ZTF-7 0.011
ama-1 Protein AMA-1 0.011
mog-4 Protein MOG-4 0.011
rpn-3 Protein RPN-3 0.011
F01G4.4 Protein F01G4.4 0.011
R90.1 Protein R90.1 0.010
nra-1 Protein NRA-1 0.010
ubxn-4 Protein UBXN-4 0.010
vps-35 Protein VPS-35 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
phl pole hole 0.027
wg wingless 0.025
Dl Delta 0.021
CG9344 CG9344 gene product from transcript CG9344-RA 0.018
N Notch 0.017
Egfr Epidermal growth factor receptor 0.016
CG2862 CG2862 gene product from transcript CG2862-RA 0.016
CG11267 CG11267 gene product from transcript CG11267-RA 0.016
dpp decapentaplegic 0.015
EcR Ecdysone receptor 0.013
CG4866 CG4866 gene product from transcript CG4866-RB 0.012
CG7603 CG7603 gene product from transcript CG7603-RA 0.011
l(2)06225 lethal (2) 06225 0.011
l(1)G0230 lethal (1) G0230 0.011
fu fused 0.010
CG9922 CG9922 gene product from transcript CG9922-RA 0.010
CG8928 CG8928 gene product from transcript CG8928-RA 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.995
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.886
Hsph1 heat shock 105kDa/110kDa protein 1 0.812
Klc1 kinesin light chain 1 0.690
Hspd1 heat shock protein 1 (chaperonin) 0.686
Iqcb1 IQ calmodulin-binding motif containing 1 0.652
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.645
Clstn1 calsyntenin 1 0.558
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.537
Rpgrip1l Rpgrip1-like 0.467
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.393
Spag9 sperm associated antigen 9 0.331
Eif3j eukaryotic translation initiation factor 3, subunit J 0.272
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.264
Hspa5 heat shock protein 5 0.242
Ncoa2 nuclear receptor coactivator 2 0.208
Cacybp calcyclin binding protein 0.199
Stip1 stress-induced phosphoprotein 1 0.199
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.197
Fam98a family with sequence similarity 98, member A 0.179
Hspa4 heat shock protein 4 0.171
Kif5c kinesin family member 5C 0.151
Kpna1 karyopherin (importin) alpha 1 0.147
Nsfl1c NSFL1 (p97) cofactor (p47) 0.130
Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein 0.122
Strap serine/threonine kinase receptor associated protein 0.118
Nars asparaginyl-tRNA synthetase 0.117
Caprin1 cell cycle associated protein 1 0.117
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.116
Hspa8 heat shock protein 8 0.109
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.096
Ufd1l ubiquitin fusion degradation 1 like 0.092
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.090
Hdac6 histone deacetylase 6 0.089
Mapk8 mitogen-activated protein kinase 8 0.089
Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha 0.085
Cct6a chaperonin containing Tcp1, subunit 6a (zeta) 0.084
Tars threonyl-tRNA synthetase 0.081
Hap1 huntingtin-associated protein 1 0.080
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.080
Eif4g2 eukaryotic translation initiation factor 4, gamma 2 0.078
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.076
Eif5b eukaryotic translation initiation factor 5B 0.076
Nphp1 nephronophthisis 1 (juvenile) homolog (human) 0.071
Igbp1 immunoglobulin (CD79A) binding protein 1 0.069
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.066
Ahi1 Abelson helper integration site 1 0.065
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.063
Bzw1 basic leucine zipper and W2 domains 1 0.061
Azin1 antizyme inhibitor 1 0.059
Iars isoleucine-tRNA synthetase 0.059
Eprs glutamyl-prolyl-tRNA synthetase 0.059
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.058
Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 0.058
Ddx3x DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked 0.056
Stk30 serine/threonine kinase 30 0.055
Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 0.054
Kpna3 karyopherin (importin) alpha 3 0.052
Klc2 kinesin light chain 2 0.051
Vamp2 vesicle-associated membrane protein 2 0.049
Rars arginyl-tRNA synthetase 0.048
Morf4l2 mortality factor 4 like 2 0.048
Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.047
Psmd12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.046
Lrpprc leucine-rich PPR-motif containing 0.045
Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked 0.044
Dtnb dystrobrevin, beta 0.044
Ide insulin degrading enzyme 0.044
Homer1 homer homolog 1 (Drosophila) 0.041
Ipo7 importin 7 0.041
Cct8 chaperonin containing Tcp1, subunit 8 (theta) 0.040
Ube4b ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) 0.039
Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 0.038
Utp6 UTP6, small subunit (SSU) processome component, homolog (yeast) 0.038
Napb N-ethylmaleimide sensitive fusion protein attachment protein beta 0.037
Api5 apoptosis inhibitor 5 0.036
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.035
Rad23b RAD23b homolog (S. cerevisiae) 0.034
Nploc4 nuclear protein localization 4 homolog (S. cerevisiae) 0.032
Cse1l chromosome segregation 1-like (S. cerevisiae) 0.031
Hspa1b heat shock protein 1B 0.031
Rusc1 RUN and SH3 domain containing 1 0.031
Mark4 MAP/microtubule affinity-regulating kinase 4 0.031
Ptges3 prostaglandin E synthase 3 (cytosolic) 0.029
Pno1 partner of NOB1 homolog (S. cerevisiae) 0.029
Kif5a kinesin family member 5A 0.029
Rab1 RAB1, member RAS oncogene family 0.028
Snap25 synaptosomal-associated protein 25 0.028
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.028
Pcbp1 poly(rC) binding protein 1 0.028
G3bp2 GTPase activating protein (SH3 domain) binding protein 2 0.027
Ckb creatine kinase, brain 0.027
Arf4 ADP-ribosylation factor 4 0.027
Sept7 septin 7 0.027
P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide 0.026
Sec63 SEC63-like (S. cerevisiae) 0.026
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.025
Tuba4a tubulin, alpha 4A 0.025
Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 0.025
Nus1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 0.024
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
STI1 Sti1p 0.110
CDC48 Cdc48p 0.073
BUD4 Bud4p 0.055
SSA2 Ssa2p 0.054
CDC10 Cdc10p 0.052
CDC3 Cdc3p 0.042
YDJ1 Ydj1p 0.030
CDC37 Cdc37p 0.023
SIS1 Sis1p 0.022
CDC12 Cdc12p 0.019
CLB3 Clb3p 0.017
MYO2 Myo2p 0.015
MDJ1 Mdj1p 0.014
NUP49 Nup49p 0.014
STU2 Stu2p 0.014
SSE1 Sse1p 0.013
SSA4 Ssa4p 0.013
UFD1 Ufd1p 0.013
PIM1 Pim1p 0.013
YLR264C-A hypothetical protein 0.012
SRD1 Srd1p 0.012
CDC15 Cdc15p 0.012
CLU1 Clu1p 0.012
CDC14 Cdc14p 0.012
ARP10 Arp10p 0.012
NUD1 Nud1p 0.011
UBA1 Uba1p 0.011
LEU2 Leu2p 0.011
YLR162W hypothetical protein 0.011
ZDS1 Zds1p 0.011
KIP1 Kip1p 0.011
YHB1 Yhb1p 0.011
STE4 Ste4p 0.011
YOL038C-A hypothetical protein 0.011
ARG8 Arg8p 0.011
CUP1-1 Cup1-1p 0.010
CHA1 Cha1p 0.010
CDC16 Cdc16p 0.010
OTU1 Otu1p 0.010
SSA1 Ssa1p 0.010
CAB3 Cab3p 0.010