IMP
Process View
The network for 'regulation of plasminogen activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of plasminogen activation
Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Thbs2 | thrombospondin 2 | 0.612 | |
| Cyr61 | cysteine rich protein 61 | 0.538 | |
| Asgr2 | asialoglycoprotein receptor 2 | 0.414 | |
| Ambp | alpha 1 microglobulin/bikunin | 0.250 | |
| Serpina10 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | 0.201 | |
| Plaur | plasminogen activator, urokinase receptor | 0.201 | |
| Mat1a | methionine adenosyltransferase I, alpha | 0.200 | |
| Apoa1 | apolipoprotein A-I | 0.168 | |
| F2 | coagulation factor II | 0.154 | |
| Wisp1 | WNT1 inducible signaling pathway protein 1 | 0.141 | |
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.134 | |
| Adamts1 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 | 0.133 | |
| Maff | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) | 0.130 | |
| Atf3 | activating transcription factor 3 | 0.124 | |
| Mbl2 | mannose-binding lectin (protein C) 2 | 0.119 | |
| Cyp2d10 | cytochrome P450, family 2, subfamily d, polypeptide 10 | 0.115 | |
| Ces1c | carboxylesterase 1C | 0.112 | |
| Itih1 | inter-alpha trypsin inhibitor, heavy chain 1 | 0.111 | |
| Fbln2 | fibulin 2 | 0.109 | |
| Ctgf | connective tissue growth factor | 0.103 | |
| Cxcl1 | chemokine (C-X-C motif) ligand 1 | 0.097 | |
| Asgr1 | asialoglycoprotein receptor 1 | 0.093 | |
| Cd44 | CD44 antigen | 0.093 | |
| Itih4 | inter alpha-trypsin inhibitor, heavy chain 4 | 0.090 | |
| Osmr | oncostatin M receptor | 0.090 | |
| Msln | mesothelin | 0.084 | |
| Pzp | pregnancy zone protein | 0.083 | |
| Cpn1 | carboxypeptidase N, polypeptide 1 | 0.073 | |
| Has1 | hyaluronan synthase1 | 0.072 | |
| Nr0b2 | nuclear receptor subfamily 0, group B, member 2 | 0.069 | |
| Plg | plasminogen | 0.067 | |
| Ttc36 | tetratricopeptide repeat domain 36 | 0.067 | |
| Rhox6 | reproductive homeobox 6 | 0.064 | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.063 | |
| Dpt | dermatopontin | 0.062 | |
| 1300017J02Rik | RIKEN cDNA 1300017J02 gene | 0.060 | |
| Gdf15 | growth differentiation factor 15 | 0.060 | |
| Hc | hemolytic complement | 0.060 | |
| Ier3 | immediate early response 3 | 0.059 | |
| Serpinc1 | serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 | 0.058 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.058 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.058 | |
| Dio1 | deiodinase, iodothyronine, type I | 0.057 | |
| Fgg | fibrinogen gamma chain | 0.055 | |
| Tnc | tenascin C | 0.055 | |
| Fgb | fibrinogen beta chain | 0.054 | |
| Mfap5 | microfibrillar associated protein 5 | 0.053 | |
| Clic3 | chloride intracellular channel 3 | 0.052 | |
| Kng1 | kininogen 1 | 0.047 | |
| Hbegf | heparin-binding EGF-like growth factor | 0.046 | |
| Gc | group specific component | 0.046 | |
| Sdsl | serine dehydratase-like | 0.045 | |
| Apoc4 | apolipoprotein C-IV | 0.045 | |
| Gm6484 | predicted gene 6484 | 0.045 | |
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.044 | |
| Ager | advanced glycosylation end product-specific receptor | 0.043 | |
| Fgfr4 | fibroblast growth factor receptor 4 | 0.042 | |
| Cfi | complement component factor i | 0.042 | |
| Apom | apolipoprotein M | 0.042 | |
| Agmat | agmatine ureohydrolase (agmatinase) | 0.041 | |
| Bik | BCL2-interacting killer | 0.041 | |
| Proc | protein C | 0.040 | |
| Apoa4 | apolipoprotein A-IV | 0.040 | |
| Hpx | hemopexin | 0.039 | |
| Gjb1 | gap junction protein, beta 1 | 0.039 | |
| Foxa2 | forkhead box A2 | 0.039 | |
| Dkk3 | dickkopf homolog 3 (Xenopus laevis) | 0.039 | |
| Sertad1 | SERTA domain containing 1 | 0.038 | |
| Timp1 | tissue inhibitor of metalloproteinase 1 | 0.038 | |
| Cldn3 | claudin 3 | 0.037 | |
| F13b | coagulation factor XIII, beta subunit | 0.036 | |
| Lipc | lipase, hepatic | 0.035 | |
| Amdhd1 | amidohydrolase domain containing 1 | 0.035 | |
| H1foo | H1 histone family, member O, oocyte-specific | 0.035 | |
| Dusp1 | dual specificity phosphatase 1 | 0.035 | |
| Prodh2 | proline dehydrogenase (oxidase) 2 | 0.035 | |
| Klf6 | Kruppel-like factor 6 | 0.034 | |
| Ahsg | alpha-2-HS-glycoprotein | 0.034 | |
| Aqp8 | aquaporin 8 | 0.033 | |
| Afm | afamin | 0.033 | |
| Rdh7 | retinol dehydrogenase 7 | 0.033 | |
| Fos | FBJ osteosarcoma oncogene | 0.032 | |
| H2-M9 | histocompatibility 2, M region locus 9 | 0.032 | |
| Adm | adrenomedullin | 0.032 | |
| Rab25 | RAB25, member RAS oncogene family | 0.032 | |
| Slc22a1 | solute carrier family 22 (organic cation transporter), member 1 | 0.032 | |
| Tpm4 | tropomyosin 4 | 0.031 | |
| Serpinf2 | serine (or cysteine) peptidase inhibitor, clade F, member 2 | 0.031 | |
| Hpn | hepsin | 0.031 | |
| Pah | phenylalanine hydroxylase | 0.031 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.031 | |
| Ccdc90b | coiled-coil domain containing 90B | 0.031 | |
| Hnf1b | HNF1 homeobox B | 0.030 | |
| Akr1c6 | aldo-keto reductase family 1, member C6 | 0.030 | |
| Serpind1 | serine (or cysteine) peptidase inhibitor, clade D, member 1 | 0.030 | |
| Krt8 | keratin 8 | 0.029 | |
| Tnfrsf12a | tumor necrosis factor receptor superfamily, member 12a | 0.029 | |
| Ppic | peptidylprolyl isomerase C | 0.029 | |
| Emp1 | epithelial membrane protein 1 | 0.029 | |
| Hgfac | hepatocyte growth factor activator | 0.028 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| PLAU | plasminogen activator, urokinase | 1.000 | |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.983 | |
| PLAUR | plasminogen activator, urokinase receptor | 0.923 | |
| PLAT | plasminogen activator, tissue | 0.189 | |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.176 | |
| C1S | complement component 1, s subcomponent | 0.172 | |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.160 | |
| ORM1 | orosomucoid 1 | 0.129 | |
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.120 | |
| FN1 | fibronectin 1 | 0.101 | |
| KNG1 | kininogen 1 | 0.062 | |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.052 | |
| GAST | gastrin | 0.046 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.044 | |
| VTN | vitronectin | 0.036 | |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.035 | |
| SPHK1 | sphingosine kinase 1 | 0.030 | |
| TNC | tenascin C | 0.020 | |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.018 | |
| CYR61 | cysteine-rich, angiogenic inducer, 61 | 0.016 | |
| INHBA | inhibin, beta A | 0.015 | |
| IL8 | interleukin 8 | 0.015 | |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.015 | |
| NNMT | nicotinamide N-methyltransferase | 0.014 | |
| OSMR | oncostatin M receptor | 0.013 | |
| AEBP1 | AE binding protein 1 | 0.013 | |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.013 | |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.012 | |
| CTGF | connective tissue growth factor | 0.012 | |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.012 | |
| EMP1 | epithelial membrane protein 1 | 0.012 | |
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.011 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.011 | |
| PLG | plasminogen | 0.010 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pzp | pregnancy-zone protein | 0.136 | |
| Plau | plasminogen activator, urokinase | 0.064 | |
| Proc | protein C | 0.056 | |
| Mbl1 | mannose-binding lectin (protein A) 1 | 0.040 | |
| Serpind1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 0.039 | |
| F2 | coagulation factor II (thrombin) | 0.037 | |
| Azgp1 | alpha-2-glycoprotein 1, zinc-binding | 0.036 | |
| Fetub | fetuin B | 0.032 | |
| Serpina10 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | 0.028 | |
| PVR | poliovirus receptor | 0.026 | |
| Gc | group specific component | 0.024 | |
| Ttc36 | tetratricopeptide repeat domain 36 | 0.023 | |
| Apoh | apolipoprotein H (beta-2-glycoprotein I) | 0.023 | |
| Cct7 | chaperonin containing Tcp1, subunit 7 (eta) | 0.022 | |
| Hpn | hepsin | 0.022 | |
| Exosc7 | exosome component 7 | 0.021 | |
| Cma1 | chymase 1, mast cell | 0.020 | |
| Cxcl1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.020 | |
| Cyp8b1 | cytochrome P450, family 8, subfamily b, polypeptide 1 | 0.020 | |
| Itih4 | inter alpha-trypsin inhibitor, heavy chain 4 | 0.019 | |
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.019 | |
| Itih1 | inter-alpha trypsin inhibitor, heavy chain 1 | 0.019 | |
| Spp2 | secreted phosphoprotein 2 | 0.019 | |
| Serpina11 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 | 0.019 | |
| Aqp8 | aquaporin 8 | 0.019 | |
| Plg | plasminogen | 0.018 | |
| Cpb2 | carboxypeptidase B2 (plasma) | 0.018 | |
| Creb3l3 | cAMP responsive element binding protein 3-like 3 | 0.018 | |
| Haao | 3-hydroxyanthranilate 3,4-dioxygenase | 0.018 | |
| Gja1 | gap junction protein, alpha 1 | 0.018 | |
| Dnase1l3 | deoxyribonuclease 1-like 3 | 0.017 | |
| Gulo | gulonolactone (L-) oxidase | 0.017 | |
| Agmat | agmatine ureohydrolase (agmatinase) | 0.017 | |
| C4bpa | complement component 4 binding protein, alpha | 0.017 | |
| Serpina1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.016 | |
| F12 | coagulation factor XII (Hageman factor) | 0.016 | |
| Ihh | Indian hedgehog | 0.016 | |
| Pcsk9 | proprotein convertase subtilisin/kexin type 9 | 0.015 | |
| Pin1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.014 | |
| Trex2 | three prime repair exonuclease 2 | 0.014 | |
| Foxa2 | forkhead box A2 | 0.013 | |
| C8b | complement component 8, beta polypeptide | 0.013 | |
| Ckm | creatine kinase, muscle | 0.013 | |
| Lgals2 | lectin, galactoside-binding, soluble, 2 | 0.013 | |
| Lao1 | L-amino acid oxidase 1 | 0.012 | |
| Kng2 | kininogen 2 | 0.012 | |
| Ambp | alpha-1-microglobulin/bikunin precursor | 0.012 | |
| Lrrc26 | leucine rich repeat containing 26 | 0.012 | |
| RGD1564614 | similar to complement factor H-related protein | 0.012 | |
| Slc10a1 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1 | 0.012 | |
| F10 | coagulation factor X | 0.012 | |
| Plaur | plasminogen activator, urokinase receptor | 0.012 | |
| Tpsab1 | tryptase alpha/beta 1 | 0.011 | |
| Hdc | histidine decarboxylase | 0.011 | |
| Cideb | cell death-inducing DFFA-like effector b | 0.011 | |
| Cfi | complement factor I | 0.011 | |
| Serpinc1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.011 | |
| Ftcd | formiminotransferase cyclodeaminase | 0.011 | |
| C1qtnf4 | C1q and tumor necrosis factor related protein 4 | 0.010 | |
| Cela3b | chymotrypsin-like elastase family, member 3B | 0.010 | |
| Nfe2 | nuclear factor, erythroid derived 2 | 0.010 |