IMP
Process View
The network for 'regulation of serine type endopeptidase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of serine type endopeptidase activity
Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fga | fibrinogen alpha chain | 0.651 | |
| Serpina1a | serine (or cysteine) peptidase inhibitor, clade A, member 1A | 0.306 | |
| Apoa1 | apolipoprotein A-I | 0.289 | |
| Alb | albumin | 0.261 | |
| Ttr | transthyretin | 0.114 | |
| Ambp | alpha 1 microglobulin/bikunin | 0.098 | |
| Msln | mesothelin | 0.097 | |
| Fbp1 | fructose bisphosphatase 1 | 0.083 | |
| Ahsg | alpha-2-HS-glycoprotein | 0.074 | |
| Fgg | fibrinogen gamma chain | 0.074 | |
| Fabp1 | fatty acid binding protein 1, liver | 0.054 | |
| Fgb | fibrinogen beta chain | 0.051 | |
| Krt19 | keratin 19 | 0.047 | |
| Pzp | pregnancy zone protein | 0.047 | |
| Gc | group specific component | 0.039 | |
| Reg3g | regenerating islet-derived 3 gamma | 0.036 | |
| Otc | ornithine transcarbamylase | 0.036 | |
| Kng1 | kininogen 1 | 0.033 | |
| Cfi | complement component factor i | 0.033 | |
| Aldob | aldolase B, fructose-bisphosphate | 0.032 | |
| Apob | apolipoprotein B | 0.031 | |
| Bhmt | betaine-homocysteine methyltransferase | 0.031 | |
| Sycn | syncollin | 0.028 | |
| Apoa2 | apolipoprotein A-II | 0.026 | |
| Serpinc1 | serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 | 0.025 | |
| Fgfbp1 | fibroblast growth factor binding protein 1 | 0.025 | |
| Fxyd3 | FXYD domain-containing ion transport regulator 3 | 0.025 | |
| Apof | apolipoprotein F | 0.023 | |
| Serpina1c | serine (or cysteine) peptidase inhibitor, clade A, member 1C | 0.021 | |
| Slc2a2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 0.021 | |
| Rgn | regucalcin | 0.020 | |
| Cnn1 | calponin 1 | 0.019 | |
| Tdo2 | tryptophan 2,3-dioxygenase | 0.017 | |
| Serpind1 | serine (or cysteine) peptidase inhibitor, clade D, member 1 | 0.017 | |
| Cyp2d26 | cytochrome P450, family 2, subfamily d, polypeptide 26 | 0.017 | |
| Serpina1e | serine (or cysteine) peptidase inhibitor, clade A, member 1E | 0.017 | |
| Mug1 | murinoglobulin 1 | 0.016 | |
| Hsd3b4 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 | 0.016 | |
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.016 | |
| Prss1 | protease, serine, 1 (trypsin 1) | 0.016 | |
| Hal | histidine ammonia lyase | 0.016 | |
| Aadac | arylacetamide deacetylase (esterase) | 0.016 | |
| Plg | plasminogen | 0.015 | |
| Rdh7 | retinol dehydrogenase 7 | 0.015 | |
| Apoh | apolipoprotein H | 0.015 | |
| F2 | coagulation factor II | 0.015 | |
| Elovl2 | elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 | 0.015 | |
| Nr1h4 | nuclear receptor subfamily 1, group H, member 4 | 0.014 | |
| Oit1 | oncoprotein induced transcript 1 | 0.014 | |
| Serpina3k | serine (or cysteine) peptidase inhibitor, clade A, member 3K | 0.014 | |
| Mall | mal, T-cell differentiation protein-like | 0.014 | |
| Ehf | ets homologous factor | 0.014 | |
| Sphk1 | sphingosine kinase 1 | 0.013 | |
| Hmgcs2 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 | 0.013 | |
| Pah | phenylalanine hydroxylase | 0.013 | |
| Serpina1d | serine (or cysteine) peptidase inhibitor, clade A, member 1D | 0.013 | |
| Klk1 | kallikrein 1 | 0.013 | |
| Mup19 | major urinary protein 19 | 0.012 | |
| Pigr | polymeric immunoglobulin receptor | 0.012 | |
| Hnf4a | hepatic nuclear factor 4, alpha | 0.012 | |
| Sult1b1 | sulfotransferase family 1B, member 1 | 0.011 | |
| Tspan1 | tetraspanin 1 | 0.011 | |
| Itih4 | inter alpha-trypsin inhibitor, heavy chain 4 | 0.011 | |
| Ly6d | lymphocyte antigen 6 complex, locus D | 0.011 | |
| Map3k6 | mitogen-activated protein kinase kinase kinase 6 | 0.011 | |
| Krt7 | keratin 7 | 0.010 | |
| Mup3 | major urinary protein 3 | 0.010 | |
| Frk | fyn-related kinase | 0.010 | |
| Serpina1b | serine (or cysteine) preptidase inhibitor, clade A, member 1B | 0.010 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| S100A10 | S100 calcium binding protein A10 | 0.991 | |
| ANXA2 | annexin A2 | 0.928 | |
| ANXA1 | annexin A1 | 0.771 | |
| S100A11 | S100 calcium binding protein A11 | 0.493 | |
| ANXA5 | annexin A5 | 0.481 | |
| VIM | vimentin | 0.350 | |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.349 | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.119 | |
| S100A6 | S100 calcium binding protein A6 | 0.097 | |
| TMSB10 | thymosin beta 10 | 0.071 | |
| EMP3 | epithelial membrane protein 3 | 0.060 | |
| FN1 | fibronectin 1 | 0.048 | |
| EMP1 | epithelial membrane protein 1 | 0.048 | |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.045 | |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.042 | |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.039 | |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.038 | |
| AHNAK | AHNAK nucleoprotein | 0.032 | |
| ITGB5 | integrin, beta 5 | 0.023 | |
| CAST | calpastatin | 0.023 | |
| NMT2 | N-myristoyltransferase 2 | 0.021 | |
| CD63 | CD63 molecule | 0.020 | |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.019 | |
| NPC2 | Niemann-Pick disease, type C2 | 0.017 | |
| MYOF | myoferlin | 0.016 | |
| CAV2 | caveolin 2 | 0.015 | |
| ANXA3 | annexin A3 | 0.014 | |
| ACTG1 | actin, gamma 1 | 0.013 | |
| CTSB | cathepsin B | 0.013 | |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.012 | |
| SH3BGRL | SH3 domain binding glutamic acid-rich protein like | 0.012 | |
| CLIC1 | chloride intracellular channel 1 | 0.011 | |
| MSN | moesin | 0.011 | |
| HEXB | hexosaminidase B (beta polypeptide) | 0.011 | |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.010 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Apcs | amyloid P component, serum | 0.938 | |
| Serpina3k | serine (or cysteine) peptidase inhibitor, clade A, member 3K | 0.847 | |
| Ahsg | alpha-2-HS-glycoprotein | 0.607 | |
| Spink1 | serine peptidase inhibitor, Kazal type 1 | 0.598 | |
| LOC299282 | Serine protease inhibitor | 0.459 | |
| Proc | protein C | 0.389 | |
| Apoa5 | apolipoprotein A-V | 0.368 | |
| C9 | complement component 9 | 0.307 | |
| Alb | albumin | 0.304 | |
| Apoh | apolipoprotein H (beta-2-glycoprotein I) | 0.256 | |
| Asgr1 | asialoglycoprotein receptor 1 | 0.247 | |
| Pemt | phosphatidylethanolamine N-methyltransferase | 0.232 | |
| Spp2 | secreted phosphoprotein 2 | 0.219 | |
| Rup2 | urinary protein 2 | 0.173 | |
| Cyp3a2 | cytochrome P450, family 3, subfamily a, polypeptide 2 | 0.169 | |
| Fabp1 | fatty acid binding protein 1, liver | 0.118 | |
| Dmgdh | dimethylglycine dehydrogenase | 0.114 | |
| Azgp1 | alpha-2-glycoprotein 1, zinc-binding | 0.109 | |
| Cyp2c13 | cytochrome P450, family 2, subfamily c, polypeptide 13 | 0.101 | |
| Ambp | alpha-1-microglobulin/bikunin precursor | 0.094 | |
| F2 | coagulation factor II (thrombin) | 0.089 | |
| C4bpb | complement component 4 binding protein, beta | 0.085 | |
| Serpind1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 0.078 | |
| Slco1b3 | solute carrier organic anion transporter family, member 1b3 | 0.074 | |
| Mbl1 | mannose-binding lectin (protein A) 1 | 0.071 | |
| Apom | apolipoprotein M | 0.066 | |
| Fga | fibrinogen alpha chain | 0.061 | |
| Slc10a1 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1 | 0.054 | |
| Afp | alpha-fetoprotein | 0.053 | |
| Pzp | pregnancy-zone protein | 0.051 | |
| Gc | group specific component | 0.049 | |
| Apoa4 | apolipoprotein A-IV | 0.048 | |
| Kynu | kynureninase (L-kynurenine hydrolase) | 0.046 | |
| Fabp12 | fatty acid binding protein 12 | 0.046 | |
| Hpx | hemopexin | 0.046 | |
| Hrg | histidine-rich glycoprotein | 0.044 | |
| Cyp2d2 | cytochrome P450, family 2, subfamily d, polypeptide 2 | 0.037 | |
| Aqp8 | aquaporin 8 | 0.036 | |
| Hpd | 4-hydroxyphenylpyruvate dioxygenase | 0.036 | |
| Cyp2b3 | cytochrome P450, family 2, subfamily b, polypeptide 3 | 0.035 | |
| Pon1 | paraoxonase 1 | 0.035 | |
| Gys2 | glycogen synthase 2 | 0.031 | |
| Serpina11 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 | 0.031 | |
| Cpb1 | carboxypeptidase B1 (tissue) | 0.028 | |
| Tdo2 | tryptophan 2,3-dioxygenase | 0.028 | |
| Apoa2 | apolipoprotein A-II | 0.027 | |
| Foxa2 | forkhead box A2 | 0.027 | |
| Ugt2b | UDP glycosyltransferase 2 family, polypeptide B | 0.026 | |
| Orm1 | orosomucoid 1 | 0.025 | |
| Serpina3m | serine (or cysteine) proteinase inhibitor, clade A, member 3M | 0.025 | |
| Fgg | fibrinogen gamma chain | 0.025 | |
| Serpinb5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.025 | |
| Itih3 | inter-alpha trypsin inhibitor, heavy chain 3 | 0.025 | |
| Kng2 | kininogen 2 | 0.023 | |
| A2m | alpha-2-macroglobulin | 0.022 | |
| LOC100361261 | rCG23560-like | 0.022 | |
| Abcb11 | ATP-binding cassette, subfamily B (MDR/TAP), member 11 | 0.022 | |
| Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.021 | |
| Igfbp1 | insulin-like growth factor binding protein 1 | 0.020 | |
| Cyp2c22 | cytochrome P450, family 2, subfamily c, polypeptide 22 | 0.020 | |
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.020 | |
| Otc | ornithine carbamoyltransferase | 0.020 | |
| Cyp4a10 | cytochrome P450, family 4, subfamily a, polypeptide 10 | 0.020 | |
| Lipc | lipase, hepatic | 0.020 | |
| Afm | afamin | 0.020 | |
| Fgb | fibrinogen beta chain | 0.019 | |
| Cyp2a2 | cytochrome P450, family 2, subfamily a, polypeptide 2 | 0.019 | |
| Dpys | dihydropyrimidinase | 0.019 | |
| Cpb2 | carboxypeptidase B2 (plasma) | 0.019 | |
| Dio1 | deiodinase, iodothyronine, type I | 0.018 | |
| Agxt2 | alanine-glyoxylate aminotransferase 2 | 0.018 | |
| Hsd17b6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.018 | |
| Gckr | glucokinase (hexokinase 4) regulator | 0.018 | |
| Cyp4f4 | cytochrome P450, family 4, subfamily f, polypeptide 4 | 0.017 | |
| Slco1a4 | solute carrier organic anion transporter family, member 1a4 | 0.017 | |
| Akap4 | A kinase (PRKA) anchor protein 4 | 0.016 | |
| Baat | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 0.016 | |
| Itih4 | inter alpha-trypsin inhibitor, heavy chain 4 | 0.016 | |
| Cyp2d1 | cytochrome P450, family 2, subfamily d, polypeptide 1 | 0.016 | |
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.016 | |
| Sult1c3 | sulfotransferase family, cytosolic, 1C, member 3 | 0.015 | |
| Mst1 | Macrophage stimulating 1 (hepatocyte growth factor-like) | 0.015 | |
| Hsd17b2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.015 | |
| Aldob | aldolase B, fructose-bisphosphate | 0.015 | |
| Cyp1a2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | 0.014 | |
| Klkb1 | kallikrein B, plasma 1 | 0.014 | |
| Acsm5 | acyl-CoA synthetase medium-chain family member 5 | 0.014 | |
| C8b | complement component 8, beta polypeptide | 0.014 | |
| Pah | phenylalanine hydroxylase | 0.013 | |
| Apoa1 | apolipoprotein A-I | 0.013 | |
| Acpp | acid phosphatase, prostate | 0.013 | |
| Serpina3n | serine (or cysteine) peptidase inhibitor, clade A, member 3N | 0.013 | |
| Mcpt4 | mast cell protease 4 | 0.012 | |
| Thrsp | thyroid hormone responsive | 0.012 | |
| RGD1560925 | similar to 2610034M16Rik protein | 0.012 | |
| Gfap | glial fibrillary acidic protein | 0.012 | |
| Foxa1 | forkhead box A1 | 0.012 | |
| Nr1h4 | nuclear receptor subfamily 1, group H, member 4 | 0.012 | |
| Serpinf2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 0.011 | |
| F12 | coagulation factor XII (Hageman factor) | 0.011 |