IMP
Process View
The network for 'negative regulation of action potential' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of action potential
Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.958 | |
| Lpar5 | lysophosphatidic acid receptor 5 | 0.900 | |
| Chrna3 | cholinergic receptor, nicotinic, alpha polypeptide 3 | 0.813 | |
| Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.741 | |
| Chrnb4 | cholinergic receptor, nicotinic, beta polypeptide 4 | 0.677 | |
| Kcnma1 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 0.636 | |
| Chrna9 | cholinergic receptor, nicotinic, alpha polypeptide 9 | 0.589 | |
| Myog | myogenin | 0.515 | |
| Htr5a | 5-hydroxytryptamine (serotonin) receptor 5A | 0.395 | |
| Oprm1 | opioid receptor, mu 1 | 0.388 | |
| Cacna1d | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.352 | |
| Th | tyrosine hydroxylase | 0.274 | |
| Cntn3 | contactin 3 | 0.267 | |
| Cplx1 | complexin 1 | 0.228 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.220 | |
| Chrna5 | cholinergic receptor, nicotinic, alpha polypeptide 5 | 0.212 | |
| Hcn3 | hyperpolarization-activated, cyclic nucleotide-gated K+ 3 | 0.210 | |
| Krtap12-1 | keratin associated protein 12-1 | 0.209 | |
| Scgn | secretagogin, EF-hand calcium binding protein | 0.203 | |
| Chrna10 | cholinergic receptor, nicotinic, alpha polypeptide 10 | 0.196 | |
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.172 | |
| Isl2 | insulin related protein 2 (islet 2) | 0.170 | |
| Psapl1 | prosaposin-like 1 | 0.157 | |
| Chrna6 | cholinergic receptor, nicotinic, alpha polypeptide 6 | 0.155 | |
| Gjd2 | gap junction protein, delta 2 | 0.147 | |
| Stk32b | serine/threonine kinase 32B | 0.139 | |
| Olfr140 | olfactory receptor 140 | 0.139 | |
| Slc6a5 | solute carrier family 6 (neurotransmitter transporter, glycine), member 5 | 0.138 | |
| Opn1mw | opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan) | 0.134 | |
| Srrm3 | serine/arginine repetitive matrix 3 | 0.133 | |
| Rapsn | receptor-associated protein of the synapse | 0.129 | |
| Kcnq2 | potassium voltage-gated channel, subfamily Q, member 2 | 0.120 | |
| Drd2 | dopamine receptor D2 | 0.113 | |
| Cacna1b | calcium channel, voltage-dependent, N type, alpha 1B subunit | 0.113 | |
| Musk | muscle, skeletal, receptor tyrosine kinase | 0.112 | |
| Rs1 | retinoschisis (X-linked, juvenile) 1 (human) | 0.111 | |
| Syt13 | synaptotagmin XIII | 0.110 | |
| Syt1 | synaptotagmin I | 0.106 | |
| Krt6a | keratin 6A | 0.104 | |
| Krtap5-1 | keratin associated protein 5-1 | 0.102 | |
| Pde6b | phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide | 0.098 | |
| Reg2 | regenerating islet-derived 2 | 0.096 | |
| Smyd1 | SET and MYND domain containing 1 | 0.095 | |
| Ecel1 | endothelin converting enzyme-like 1 | 0.092 | |
| Lcn8 | lipocalin 8 | 0.091 | |
| Tex19.1 | testis expressed gene 19.1 | 0.088 | |
| Rit2 | Ras-like without CAAX 2 | 0.087 | |
| Otog | otogelin | 0.086 | |
| Gprin1 | G protein-regulated inducer of neurite outgrowth 1 | 0.078 | |
| Chrna7 | cholinergic receptor, nicotinic, alpha polypeptide 7 | 0.077 | |
| Mab21l2 | mab-21-like 2 (C. elegans) | 0.075 | |
| Dcx | doublecortin | 0.075 | |
| Smad9 | MAD homolog 9 (Drosophila) | 0.074 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.074 | |
| St8sia3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 | 0.073 | |
| Opn1sw | opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) | 0.072 | |
| Pramel7 | preferentially expressed antigen in melanoma like 7 | 0.071 | |
| Rgs8 | regulator of G-protein signaling 8 | 0.070 | |
| Rgs7 | regulator of G protein signaling 7 | 0.070 | |
| Gjc2 | gap junction protein, gamma 2 | 0.068 | |
| Tssk1 | testis-specific serine kinase 1 | 0.068 | |
| Cntn2 | contactin 2 | 0.067 | |
| Drd4 | dopamine receptor D4 | 0.067 | |
| Igfbpl1 | insulin-like growth factor binding protein-like 1 | 0.064 | |
| Sfrp5 | secreted frizzled-related sequence protein 5 | 0.062 | |
| Myod1 | myogenic differentiation 1 | 0.062 | |
| Lhx3 | LIM homeobox protein 3 | 0.061 | |
| Gzmm | granzyme M (lymphocyte met-ase 1) | 0.060 | |
| Alk | anaplastic lymphoma kinase | 0.059 | |
| Thrb | thyroid hormone receptor beta | 0.059 | |
| Chrnb3 | cholinergic receptor, nicotinic, beta polypeptide 3 | 0.059 | |
| Kcns2 | K+ voltage-gated channel, subfamily S, 2 | 0.058 | |
| Has1 | hyaluronan synthase1 | 0.058 | |
| Onecut1 | one cut domain, family member 1 | 0.056 | |
| Gpr12 | G-protein coupled receptor 12 | 0.055 | |
| Sult4a1 | sulfotransferase family 4A, member 1 | 0.055 | |
| Clcn1 | chloride channel 1 | 0.054 | |
| Gckr | glucokinase regulatory protein | 0.054 | |
| Slc5a7 | solute carrier family 5 (choline transporter), member 7 | 0.053 | |
| Diras1 | DIRAS family, GTP-binding RAS-like 1 | 0.052 | |
| Gabrb3 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 | 0.051 | |
| Dpf3 | D4, zinc and double PHD fingers, family 3 | 0.049 | |
| Slc8a3 | solute carrier family 8 (sodium/calcium exchanger), member 3 | 0.048 | |
| Cct6b | chaperonin containing Tcp1, subunit 6b (zeta) | 0.048 | |
| Nell2 | NEL-like 2 (chicken) | 0.047 | |
| Crygs | crystallin, gamma S | 0.046 | |
| Gabrg2 | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | 0.046 | |
| Dbh | dopamine beta hydroxylase | 0.046 | |
| Gal | galanin | 0.045 | |
| Retnlb | resistin like beta | 0.045 | |
| Gh | growth hormone | 0.044 | |
| Ncam2 | neural cell adhesion molecule 2 | 0.044 | |
| Aanat | arylalkylamine N-acetyltransferase | 0.044 | |
| Atcay | ataxia, cerebellar, Cayman type homolog (human) | 0.044 | |
| Omp | olfactory marker protein | 0.043 | |
| Kcnk4 | potassium channel, subfamily K, member 4 | 0.043 | |
| Mybph | myosin binding protein H | 0.043 | |
| Avil | advillin | 0.043 | |
| Serpind1 | serine (or cysteine) peptidase inhibitor, clade D, member 1 | 0.042 | |
| Pdc | phosducin | 0.042 |
