The network for 'response to ammonium ion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to ammonium ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus.

Rattus norvegicus
Name Description Probability Func Analog Organism
Drd1a dopamine receptor D1A 0.554
RT1-Ba RT1 class II, locus Ba 0.478
Mag myelin-associated glycoprotein 0.437
RT1-Db1 RT1 class II, locus Db1 0.329
Chrna1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.303
Oprk1 opioid receptor, kappa 1 0.277
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.262
Kl Klotho 0.261
Egr2 early growth response 2 0.254
Gfra2 GDNF family receptor alpha 2 0.244
Scn10a sodium channel, voltage-gated, type X, alpha subunit 0.242
Avp arginine vasopressin 0.210
Grm5 glutamate receptor, metabotropic 5 0.208
Ccbp2 chemokine binding protein 2 0.199
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.197
Hrh4 histamine receptor H4 0.196
RT1-Bb RT1 class II, locus Bb 0.193
Htr5a 5-hydroxytryptamine (serotonin) receptor 5A 0.187
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.176
Gpr12 G protein-coupled receptor 12 0.175
Sstr2 somatostatin receptor 2 0.175
Grik1 glutamate receptor, ionotropic, kainate 1 0.172
Hpca hippocalcin 0.168
Gcm1 glial cells missing homolog 1 (Drosophila) 0.166
Clstn3 calsyntenin 3 0.161
Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 0.158
Gper G protein-coupled estrogen receptor 1 0.156
Gja6 gap junction protein, alpha 6 0.156
Slc8a3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.155
Cacnb4 calcium channel, voltage-dependent, beta 4 subunit 0.152
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.152
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.149
Acr acrosin 0.148
Omp olfactory marker protein 0.148
Vom2r53 vomeronasal 2 receptor, 53 0.148
Chrnb1 cholinergic receptor, nicotinic, beta 1 (muscle) 0.146
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.145
Crhr2 corticotropin releasing hormone receptor 2 0.142
Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain 0.142
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.142
Chrna6 cholinergic receptor, nicotinic, alpha 6 0.141
Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 0.139
Nfasc neurofascin 0.139
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.138
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.137
Gad2 glutamate decarboxylase 2 0.136
Rgs8 regulator of G-protein signaling 8 0.134
Ptafr platelet-activating factor receptor 0.133
Oprl1 opiate receptor-like 1 0.132
Ctsj cathepsin J 0.130
Cpb1 carboxypeptidase B1 (tissue) 0.130
Prlhr prolactin releasing hormone receptor 0.129
Ccl4 chemokine (C-C motif) ligand 4 0.128
Mchr1 melanin-concentrating hormone receptor 1 0.126
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.126
Gabra3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.126
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.125
Svs3a seminal vesicle secretory protein 3A 0.123
Psp parotid secretory protein 0.122
Cntn3 contactin 3 (plasmacytoma associated) 0.122
Oprm1 opioid receptor, mu 1 0.121
Neurl3 neuralized homolog 3 (Drosophila) 0.121
Grm1 glutamate receptor, metabotropic 1 0.120
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.120
Slc7a12 solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 0.119
Phkg1 phosphorylase kinase, gamma 1 0.118
Sstr1 somatostatin receptor 1 0.118
Fev FEV (ETS oncogene family) 0.117
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.116
Agtr1a angiotensin II receptor, type 1a 0.115
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.114
Uncx UNC homeobox 0.113
Csf3 colony stimulating factor 3 (granulocyte) 0.112
Coro1b coronin, actin-binding protein, 1B 0.112
Slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.112
Npy5r neuropeptide Y receptor Y5 0.111
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.111
Cgm4 carcinoembryonic antigen gene family 4 0.111
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.110
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.109
Glra1 glycine receptor, alpha 1 0.108
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.108
Dcc deleted in colorectal carcinoma 0.108
Tnni1 troponin I type 1 (skeletal, slow) 0.106
Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 0.103
Junb jun B proto-oncogene 0.103
Gabra2 gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2 0.102
Impg2 interphotoreceptor matrix proteoglycan 2 0.102
Ppp2r2c protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform 0.101
Kcnq2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.100
Avpr1b arginine vasopressin receptor 1B 0.098
Cxcl2 chemokine (C-X-C motif) ligand 2 0.098
Gabra5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.097
Vip vasoactive intestinal peptide 0.097
RGD1564664 similar to LOC387763 protein 0.097
Gabrd gamma-aminobutyric acid (GABA) A receptor, delta 0.096
Grm6 glutamate receptor, metabotropic 6 0.096
Olr1493 olfactory receptor gene Olr1493 0.095
Cacng5 calcium channel, voltage-dependent, gamma subunit 5 0.094
Epor erythropoietin receptor 0.094
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.131
DLG4 discs, large homolog 4 (Drosophila) 0.060
LAT linker for activation of T cells 0.055
FYN FYN oncogene related to SRC, FGR, YES 0.045
CRHR1 corticotropin releasing hormone receptor 1 0.033
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.031
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.028
INSR insulin receptor 0.026
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.022
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.020
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.019
CRH corticotropin releasing hormone 0.018
ADORA2A adenosine A2a receptor 0.016
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.013
GRB2 growth factor receptor-bound protein 2 0.013
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.012
MYD88 myeloid differentiation primary response gene (88) 0.012
DUSP23 dual specificity phosphatase 23 0.011
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.011
IRS1 insulin receptor substrate 1 0.010
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.010
TICAM2 toll-like receptor adaptor molecule 2 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 1.000
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 1.000
Drd2 dopamine receptor D2 0.992
Nos1 nitric oxide synthase 1, neuronal 0.985
Pparg peroxisome proliferator activated receptor gamma 0.944
Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 0.918
Mef2d myocyte enhancer factor 2D 0.898
Pnpla2 patatin-like phospholipase domain containing 2 0.832
Grid1 glutamate receptor, ionotropic, delta 1 0.808
Grm1 glutamate receptor, metabotropic 1 0.743
Cckbr cholecystokinin B receptor 0.677
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.657
Drd1a dopamine receptor D1A 0.639
Prkce protein kinase C, epsilon 0.628
Homer1 homer homolog 1 (Drosophila) 0.602
Ldb3 LIM domain binding 3 0.519
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.511
Npy2r neuropeptide Y receptor Y2 0.485
Lep leptin 0.480
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.468
Shank2 SH3/ankyrin domain gene 2 0.444
Lepr leptin receptor 0.399
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.394
Prkaca protein kinase, cAMP dependent, catalytic, alpha 0.371
Insr insulin receptor 0.362
Actn2 actinin alpha 2 0.323
Ar androgen receptor 0.321
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.311
Ncor2 nuclear receptor co-repressor 2 0.288
Nxph1 neurexophilin 1 0.249
Pgr progesterone receptor 0.247
Kcnk4 potassium channel, subfamily K, member 4 0.231
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.229
Plcg1 phospholipase C, gamma 1 0.227
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 0.215
Dlg4 discs, large homolog 4 (Drosophila) 0.214
Prkcb protein kinase C, beta 0.211
Crhr1 corticotropin releasing hormone receptor 1 0.203
Npy1r neuropeptide Y receptor Y1 0.203
Adrb1 adrenergic receptor, beta 1 0.202
Gabrg2 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 0.202
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.199
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.197
Kl klotho 0.196
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.195
Plcb1 phospholipase C, beta 1 0.193
Dctn1 dynactin 1 0.191
Gabra2 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 0.189
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.185
Rit2 Ras-like without CAAX 2 0.182
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.182
Oprk1 opioid receptor, kappa 1 0.176
Gjd2 gap junction protein, delta 2 0.164
Adora2a adenosine A2a receptor 0.162
Nsf N-ethylmaleimide sensitive fusion protein 0.160
Bsn bassoon 0.155
Adcyap1 adenylate cyclase activating polypeptide 1 0.154
Ptgs2 prostaglandin-endoperoxide synthase 2 0.151
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.145
Shc3 src homology 2 domain-containing transforming protein C3 0.140
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.138
Hrh1 histamine receptor H1 0.134
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 0.128
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.128
Slc12a5 solute carrier family 12, member 5 0.125
Kcns2 K+ voltage-gated channel, subfamily S, 2 0.124
Prnp prion protein 0.119
Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 0.115
Grb10 growth factor receptor bound protein 10 0.113
Ncam2 neural cell adhesion molecule 2 0.112
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.111
Esr1 estrogen receptor 1 (alpha) 0.110
Prkcc protein kinase C, gamma 0.109
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.109
Syn2 synapsin II 0.106
Nxph2 neurexophilin 2 0.102
Emx1 empty spiracles homolog 1 (Drosophila) 0.101
Grm2 glutamate receptor, metabotropic 2 0.100
Cga glycoprotein hormones, alpha subunit 0.100
Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 0.100
Gad2 glutamic acid decarboxylase 2 0.098
Per2 period homolog 2 (Drosophila) 0.097
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.096
Htr5a 5-hydroxytryptamine (serotonin) receptor 5A 0.096
Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 0.095
St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.095
Cav1 caveolin 1, caveolae protein 0.093
H2-Aa histocompatibility 2, class II antigen A, alpha 0.093
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.093
Rs1 retinoschisis (X-linked, juvenile) 1 (human) 0.092
Syt1 synaptotagmin I 0.092
Cntn4 contactin 4 0.082
Adrb2 adrenergic receptor, beta 2 0.082
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.081
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.078
Lhx6 LIM homeobox protein 6 0.077
Slc1a6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 0.077
Glra1 glycine receptor, alpha 1 subunit 0.075
Epha6 Eph receptor A6 0.072
Gpr12 G-protein coupled receptor 12 0.072
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism