The network for 'regulation of synaptic plasticity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of synaptic plasticity

A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.

Name Description Probability Func Analog Organism
Prkcg protein kinase C, gamma 0.555
Gria2 glutamate receptor, ionotropic, AMPA 2 0.517
Adora2a adenosine A2a receptor 0.514
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.388
S100a10 S100 calcium binding protein A10 0.375
Hpca hippocalcin 0.349
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.291
Nfasc neurofascin 0.281
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.270
Dlg4 discs, large homolog 4 (Drosophila) 0.257
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.255
S100a8 S100 calcium binding protein A8 0.252
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.247
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.226
Aqp2 aquaporin 2 (collecting duct) 0.196
B3gat1 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) 0.193
Csf1 colony stimulating factor 1 (macrophage) 0.192
Gfap glial fibrillary acidic protein 0.190
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.186
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.176
Grm7 glutamate receptor, metabotropic 7 0.168
Lep leptin 0.167
Alb albumin 0.162
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.152
Gria1 glutamate receptor, ionotropic, AMPA 1 0.151
Gna15 guanine nucleotide binding protein, alpha 15 0.150
Onecut1 one cut homeobox 1 0.147
Pou3f3 POU class 3 homeobox 3 0.146
Ptch1 patched homolog 1 (Drosophila) 0.143
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.135
Cfp complement factor properdin 0.133
Rabac1 Rab acceptor 1 (prenylated) 0.132
Gal galanin prepropeptide 0.132
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.132
Apbb1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.130
Crhbp corticotropin releasing hormone binding protein 0.129
Mc5r melanocortin 5 receptor 0.121
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.116
Stxbp1 syntaxin binding protein 1 0.112
Bcan brevican 0.111
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.111
Dlg3 discs, large homolog 3 (Drosophila) 0.109
Sfrp4 secreted frizzled-related protein 4 0.109
Anxa2 annexin A2 0.109
Oprd1 opioid receptor, delta 1 0.108
Anxa1 annexin A1 0.105
Rgs8 regulator of G-protein signaling 8 0.100
Grpr gastrin releasing peptide receptor 0.100
Apba2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.100
Stx1a syntaxin 1A (brain) 0.098
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.097
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.095
Pacs1 phosphofurin acidic cluster sorting protein 1 0.094
Accn3 amiloride-sensitive cation channel 3 0.093
Camkv CaM kinase-like vesicle-associated 0.093
Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 0.093
S100a9 S100 calcium binding protein A9 0.092
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.089
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.088
Apba1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.087
Anxa5 annexin A5 0.086
Dio2 deiodinase, iodothyronine, type II 0.085
Pip5k1c phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.084
Nlgn3 neuroligin 3 0.084
Pdyn prodynorphin 0.083
Itgb4 integrin, beta 4 0.081
Lphn1 latrophilin 1 0.081
Mmp7 matrix metallopeptidase 7 0.081
Adra2c adrenergic, alpha-2C-, receptor 0.081
Pctk1 PCTAIRE protein kinase 1 0.081
Pde1b phosphodiesterase 1B, calmodulin-dependent 0.080
Adora1 adenosine A1 receptor 0.079
Umod uromodulin 0.079
Vip vasoactive intestinal peptide 0.079
Aqp8 aquaporin 8 0.079
Tecr trans-2,3-enoyl-CoA reductase 0.078
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.078
Tgfbr3 transforming growth factor, beta receptor III 0.078
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.078
Reg3g regenerating islet-derived 3 gamma 0.077
Pgf placental growth factor 0.076
Vegp2 von Ebners gland protein 2 0.075
Pex5l peroxisomal biogenesis factor 5-like 0.075
Agtr1a angiotensin II receptor, type 1a 0.073
Sstr5 somatostatin receptor 5 0.073
Odf4 outer dense fiber of sperm tails 4 0.072
Lrrc7 leucine rich repeat containing 7 0.072
Pnlip pancreatic lipase 0.072
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.071
Fgf14 fibroblast growth factor 14 0.071
Galr3 galanin receptor 3 0.071
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.071
Zc3h7b zinc finger CCCH-type containing 7B 0.070
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.070
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.070
Mos Moloney sarcoma oncogene 0.070
Trim3 tripartite motif-containing 3 0.070
Slc7a3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 0.069
Mmp13 matrix metallopeptidase 13 0.069
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.068
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
unc-9 Protein UNC-9 0.187
nlg-1 Protein NLG-1 0.136
unc-115 Protein UNC-115 0.108
F45E4.3 Protein F45E4.3 0.083
cam-1 Protein CAM-1 0.069
rig-6 Protein RIG-6 0.067
CELE_C10C6.6 Protein C10C6.6 0.063
egl-18 Protein EGL-18 0.063
glr-5 Protein GLR-5 0.063
unc-82 Protein UNC-82 0.063
dep-1 Protein DEP-1 0.057
pha-4 Protein PHA-4 0.055
soc-2 Protein SOC-2 0.050
unc-62 Protein UNC-62 0.049
glp-1 Protein GLP-1 0.048
ptp-4 Protein PTP-4 0.043
dpy-23 Protein DPY-23 0.042
snt-1 Protein SNT-1 0.040
pal-1 Protein PAL-1 0.040
rig-1 Protein RIG-1 0.040
unc-43 Protein UNC-43 0.039
gld-1 Protein GLD-1 0.038
madd-4 Protein MADD-4 0.037
unc-104 Protein UNC-104 0.037
unc-1 Protein UNC-1 0.036
tax-6 Protein TAX-6 0.035
C33A11.1 Protein C33A11.1 0.035
CELE_T13H5.1 Protein T13H5.1 0.035
goa-1 Protein GOA-1 0.033
pry-1 Protein PRY-1 0.033
magi-1 Protein MAGI-1 0.033
deb-1 Protein DEB-1 0.032
pdf-1 Protein PDF-1 0.032
flt-1 Protein FLT-1 0.031
add-1 Protein ADD-1 0.031
casy-1 Protein CASY-1 0.031
gar-3 Protein GAR-3 0.030
pdfr-1 Protein PDFR-1 0.030
aat-5 Protein AAT-5 0.029
mdt-8 Protein MDT-8 0.029
hlh-30 Protein HLH-30 0.028
apa-2 Protein APA-2 0.027
sup-17 Protein SUP-17 0.027
T14B1.1 Protein T14B1.1 0.027
mig-5 Protein MIG-5 0.027
D1043.1 Protein D1043.1 0.026
ist-1 Protein IST-1 0.026
egl-27 Protein EGL-27 0.025
CELE_W05H12.1 Protein W05H12.1 0.025
lst-4 Protein LST-4 0.025
pdl-1 Protein PDL-1 0.025
lag-1 Protein LAG-1 0.025
unc-17 Protein UNC-17 0.024
unc-42 Protein UNC-42 0.024
lin-17 Protein LIN-17 0.024
rskn-1 Protein RSKN-1 0.024
clh-5 Protein CLH-5 0.024
dnj-5 Protein DNJ-5 0.024
hmr-1 Protein HMR-1 0.023
ast-1 Protein AST-1 0.023
lin-3 Protein LIN-3 0.023
hlh-2 Protein HLH-2 0.023
unc-32 Protein UNC-32 0.023
ten-1 Protein TEN-1 0.023
mes-4 Protein MES-4 0.023
elt-6 Protein ELT-6 0.023
sli-1 Protein SLI-1 0.023
mes-3 Protein MES-3 0.023
age-1 Protein AGE-1 0.022
daf-3 Protein DAF-3 0.022
ZC412.3 Protein ZC412.3 0.022
trp-1 Protein TRP-1 0.022
pitp-1 Protein PITP-1 0.022
ttr-28 Protein TTR-28 0.022
hlh-14 Protein HLH-14 0.022
CELE_T27C4.1 Protein T27C4.1 0.021
nab-1 Protein NAB-1 0.021
M01A8.2 Protein M01A8.2 0.021
mek-2 Protein MEK-2 0.021
tom-1 Protein TOM-1 0.021
dbl-1 Protein DBL-1 0.021
F46C5.6 Protein F46C5.6 0.021
hrdl-1 Protein HRDL-1 0.021
axl-1 Protein AXL-1 0.021
yop-1 Protein YOP-1 0.021
F10E7.9 Protein F10E7.9 0.020
nhr-71 Protein NHR-71 0.020
F22D3.2 Protein F22D3.2 0.020
lir-1 Protein LIR-1 0.020
aak-2 Protein AAK-2 0.020
fkh-9 Protein FKH-9 0.020
C50E3.5 Protein C50E3.5 0.020
F56C9.8 Protein F56C9.8 0.020
ida-1 Protein IDA-1 0.020
CELE_ZK1073.1 Protein ZK1073.1 0.020
ldb-1 Protein LDB-1 0.020
ins-1 Protein INS-1 0.019
F30A10.3 Protein F30A10.3 0.019
hnd-1 Protein HND-1 0.019
gei-18 Protein GEI-18 0.019
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Danio rerio
Name Description Probability Func Analog Organism
gria1a glutamate receptor, ionotropic, AMPA 1a 0.785
nlgn2a neuroligin 2a 0.600
nlgn2b neuroligin 2b 0.498
dlg1 discs, large (Drosophila) homolog 1 0.497
gria2a glutamate receptor, ionotropic, AMPA 2a 0.488
dcc deleted in colorectal carcinoma 0.451
gria4a glutamate receptor, ionotropic, AMPA 4a 0.406
nf1a neurofibromin 1a 0.400
scn8aa sodium channel, voltage-gated, type VIII, alpha a 0.392
nlgn4b neuroligin 4b 0.390
trpc1 transient receptor potential cation channel, subfamily C, member 1 0.349
pcsk1nl proprotein convertase subtilisin/kexin type 1 inhibitor, like 0.323
lepr leptin receptor 0.322
ascl1a achaete-scute complex-like 1a (Drosophila) 0.309
eno2 enolase 2 0.306
sema3d semaphorin 3d 0.302
egr1 early growth response 1 0.301
grin1a glutamate receptor, ionotropic, N-methyl D-aspartate 1a 0.297
sncb synuclein, beta 0.287
nf1b neurofibromin 1b 0.286
gap43 growth associated protein 43 0.284
ptpra protein tyrosine phosphatase, receptor type, A 0.282
gria2b glutamate receptor, ionotropic, AMPA 2b 0.279
ucn3l urocortin 3, like 0.277
her4.2 hairy-related 4.2 0.275
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.269
dlg2 discs, large (Drosophila) homolog 2 0.269
neurod neurogenic differentiation 0.269
gria3b glutamate receptor, ionotrophic, AMPA 3b 0.262
gna13b guanine nucleotide binding protein (G protein), alpha 13b 0.247
epas1b endothelial PAS domain protein 1b 0.231
si:dkey-24g18.2 si:dkey-24g18.2 0.231
bactin2 bactin2 0.228
slc1a2b solute carrier family 1 (glial high affinity glutamate transporter), member 2b 0.225
zgc:162213 zgc:162213 0.221
nlgn1 neuroligin 1 0.218
cdh23 cadherin-like 23 0.208
stmn1b stathmin 1b 0.204
gnao1a guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a 0.202
nxph1 neurexophilin 1 0.196
gria3a glutamate receptor, ionotropic, AMPA 3a 0.193
lamb2 laminin, beta 2 (laminin S) 0.193
nrg1 neuregulin 1 0.181
mbp myelin basic protein 0.177
adrb2a adrenergic receptor, beta 2a 0.175
cacna1ab calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b 0.175
adcyap1b adenylate cyclase activating polypeptide 1b 0.168
drd2l dopamine receptor D2 like 0.168
gria4b glutamate receptor, ionotropic, AMPA 4b 0.162
sc:d0319 sc:d0319 0.161
gpr143 G protein-coupled receptor 143 0.161
dusp5 dual specificity phosphatase 5 0.160
stx1b syntaxin 1B 0.155
klf4a Kruppel-like transcription factor 4a 0.151
egr2b early growth response 2b 0.150
fmr1 fragile X mental retardation 1 0.145
dbx1a developing brain homeobox 1a 0.137
ap1b1 adaptor-related protein complex 1, beta 1 subunit 0.136
ppp3ca protein phosphatase 3, catalytic subunit, alpha isozyme 0.135
snap25a synaptosome-associated protein 25a 0.134
pi4kb phosphatidylinositol 4-kinase, catalytic, beta 0.134
LOC100007758 novel protein similar to vertebrate SLIT and NTRK-like family, member 3 (SLITRK3) 0.133
zgc:162964 zgc:162964 0.133
mapk3 mitogen-activated protein kinase 3 0.132
adipor1a adiponectin receptor 1a 0.131
gad1b glutamate decarboxylase 1b 0.130
LOC794630 retinol-binding protein 3-like 0.130
baiap2l1a BAI1-associated protein 2-like 1a 0.130
ptpn11a protein tyrosine phosphatase, non-receptor type 11, a 0.126
vamp2 vesicle-associated membrane protein 2 0.125
nlgn3a neuroligin 3a 0.124
elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.124
stmn4l stathmin-like 4, like 0.122
stmn2a stathmin-like 2a 0.121
pparg peroxisome proliferator activated receptor gamma 0.121
wu:fc07b10 wu:fc07b10 0.121
neurog1 neurogenin 1 0.120
ache acetylcholinesterase 0.118
sybu syntabulin (syntaxin-interacting) 0.117
ca2 carbonic anhydrase II 0.117
vps26bl vacuolar protein sorting 26 homolog B, like 0.116
slc25a25a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a 0.113
mbnl2 muscleblind-like 2 (Drosophila) 0.113
zgc:112986 zgc:112986 0.113
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.111
mef2a myocyte enhancer factor 2a 0.109
glrbb glycine receptor, beta b 0.108
islr2 immunoglobulin superfamily containing leucine-rich repeat 2 0.108
rlbp1a retinaldehyde binding protein 1a 0.108
zgc:85727 zgc:85727 0.107
mpz myelin protein zero 0.105
pink1 PTEN induced putative kinase 1 0.105
prox2 prospero homeobox 2 0.105
si:dkey-202c5.1 si:dkey-202c5.1 0.105
sema3ab semaphorin 3ab 0.104
chat choline acetyltransferase 0.103
p2rx8 purinergic receptor P2X, ligand-gated ion channel, 8 0.102
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.101
tm9sf2 transmembrane 9 superfamily member 2 0.101
elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.101
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.990
Rab11 Rab-protein 11 0.873
CaMKII Calcium/calmodulin-dependent protein kinase II 0.854
Alk CG8250 gene product from transcript CG8250-RA 0.615
brp bruchpilot 0.562
wit wishful thinking 0.437
Snap25 Synapse protein 25 0.427
Tbh Tyramine beta hydroxylase 0.381
Ank2 Ankyrin 2 0.344
dnc dunce 0.265
G-oalpha47A G protein oalpha 47A 0.239
cpx complexin 0.219
CG13253 CG13253 gene product from transcript CG13253-RB 0.186
neuroligin CG13772 gene product from transcript CG13772-RA 0.165
trio CG18214 gene product from transcript CG18214-RA 0.148
Mob2 CG11711 gene product from transcript CG11711-RC 0.132
Nrx-1 Neurexin 1 0.131
PP2A-B' CG7913 gene product from transcript CG7913-RK 0.126
fd85E forkhead domain 85E 0.126
stai stathmin 0.125
CG42629 CG42629 gene product from transcript CG42629-RB 0.125
Syx1A Syntaxin 1A 0.115
Rab3 Rab-protein 3 0.112
atl atlastin 0.112
nwk nervous wreck 0.108
TBPH CG10327 gene product from transcript CG10327-RC 0.102
unc-13 CG2999 gene product from transcript CG2999-RA 0.099
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.097
Dsk Drosulfakinin 0.095
Nmdar1 NMDA receptor 1 0.084
oa2 octopamine receptor 2 0.081
Khc-73 Kinesin-73 0.075
CG13792 CG13792 gene product from transcript CG13792-RA 0.075
CG32635 CG32635 gene product from transcript CG32635-RA 0.066
CG12187 CG12187 gene product from transcript CG12187-RA 0.066
Dab Disabled 0.065
Syb Synaptobrevin 0.061
GluRIIA Glutamate receptor IIA 0.059
Cdk5alpha Cdk5 activator-like protein 0.059
spas spastin 0.049
unc-104 CG8566 gene product from transcript CG8566-RB 0.049
CrebB-17A Cyclic-AMP response element binding protein B at 17A 0.040
mol moladietz 0.038
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.038
Sema-1a CG18405 gene product from transcript CG18405-RD 0.037
sei seizure 0.037
Gad1 Glutamic acid decarboxylase 1 0.037
Pk61C Protein kinase 61C 0.036
Rala Ras-related protein 0.036
NPFR1 neuropeptide F receptor 0.034
usp ultraspiracle 0.033
Vrp1 Verprolin 1 0.033
Pka-R1 cAMP-dependent protein kinase R1 0.033
par-1 CG8201 gene product from transcript CG8201-RA 0.031
RanBPM Ran-binding protein M 0.031
Syx6 Syntaxin 6 0.030
Su(H) Suppressor of Hairless 0.029
caz cabeza 0.029
Hsf Heat shock factor 0.029
Mad Mothers against dpp 0.028
Pp2A-29B Protein phosphatase 2A at 29B 0.027
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.026
PIP5K59B CG3682 gene product from transcript CG3682-RE 0.024
Syx7 Syntaxin 7 0.024
mtt mangetout 0.024
InR Insulin-like receptor 0.023
5-HT1A Serotonin receptor 1A 0.022
Ric Ras which interacts with Calmodulin 0.022
tomosyn CG17762 gene product from transcript CG17762-RB 0.022
Ef1alpha48D Elongation factor 1alpha48D 0.021
amon amontillado 0.021
jeb jelly belly 0.021
Cip4 CG15015 gene product from transcript CG15015-RA 0.020
RASSF8 CG5053 gene product from transcript CG5053-RA 0.020
rtGEF rho-type guanine exchange factor 0.020
NT1 Neurotrophin 1 0.020
Rheb CG1081 gene product from transcript CG1081-RA 0.019
Oamb Octopamine receptor in mushroom bodies 0.019
Nf1 Neurofibromin 1 0.019
Csp Cysteine string protein 0.018
Frq1 Frequenin 1 0.017
Rop Ras opposite 0.016
amn amnesiac 0.016
drd drop dead 0.016
mle maleless 0.015
Ddc Dopa decarboxylase 0.015
HGTX CG13475 gene product from transcript CG13475-RB 0.015
CG4699 CG4699 gene product from transcript CG4699-RJ 0.014
Ide Insulin degrading metalloproteinase 0.014
TyrR Tyramine receptor 0.014
Syx5 Syntaxin 5 0.014
slo slowpoke 0.014
Tsp68C Tetraspanin 68C 0.014
2mit CG42573 gene product from transcript CG42573-RA 0.013
CG33960 CG33960 gene product from transcript CG33960-RB 0.013
osk oskar 0.013
Lrrk Leucine-rich repeat kinase 0.013
CG43073 CG43073 gene product from transcript CG43073-RF 0.013
mura murashka 0.013
Syn Synapsin 0.013
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.999
DLG4 discs, large homolog 4 (Drosophila) 0.999
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.997
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.993
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.992
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.990
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.989
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.971
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.957
SNAP25 synaptosomal-associated protein, 25kDa 0.948
VAMP3 vesicle-associated membrane protein 3 (cellubrevin) 0.948
HIPK2 homeodomain interacting protein kinase 2 0.931
APP amyloid beta (A4) precursor protein 0.914
HDAC4 histone deacetylase 4 0.885
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.863
ITSN1 intersectin 1 (SH3 domain protein) 0.847
GSK3B glycogen synthase kinase 3 beta 0.839
FYN FYN oncogene related to SRC, FGR, YES 0.838
DNM1 dynamin 1 0.806
MAPT microtubule-associated protein tau 0.800
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.795
MAP2K1 mitogen-activated protein kinase kinase 1 0.788
PSEN1 presenilin 1 0.786
NCOA1 nuclear receptor coactivator 1 0.736
EGR3 early growth response 3 0.729
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.722
S100A1 S100 calcium binding protein A1 0.706
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.689
EGR1 early growth response 1 0.682
PRKCG protein kinase C, gamma 0.678
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.678
STX1A syntaxin 1A (brain) 0.647
VAC14 Vac14 homolog (S. cerevisiae) 0.638
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.638
TPBG trophoblast glycoprotein 0.620
STX5 syntaxin 5 0.613
RNF11 ring finger protein 11 0.562
SPRR2A small proline-rich protein 2A 0.559
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.546
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.537
OPTN optineurin 0.523
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.515
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.492
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.473
BCL2L1 BCL2-like 1 0.457
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.444
PEBP1 phosphatidylethanolamine binding protein 1 0.430
ABL2 v-abl Abelson murine leukemia viral oncogene homolog 2 0.420
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.386
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.381
DLG2 discs, large homolog 2 (Drosophila) 0.365
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.358
MKL1 megakaryoblastic leukemia (translocation) 1 0.353
EGR2 early growth response 2 0.352
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.349
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.348
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.335
RXRA retinoid X receptor, alpha 0.327
OCRL oculocerebrorenal syndrome of Lowe 0.325
SLC6A2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 0.325
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.321
KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.319
FGFR1 fibroblast growth factor receptor 1 0.310
EEA1 early endosome antigen 1 0.309
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.302
ALAS1 aminolevulinate, delta-, synthase 1 0.298
RHEB Ras homolog enriched in brain 0.295
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.294
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.284
KIAA0408 KIAA0408 0.281
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.280
KSR1 kinase suppressor of ras 1 0.280
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.275
FLNB filamin B, beta 0.274
RABIF RAB interacting factor 0.273
CRIPT cysteine-rich PDZ-binding protein 0.271
MYOCD myocardin 0.266
NCKIPSD NCK interacting protein with SH3 domain 0.266
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.265
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.265
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.264
RAP1A RAP1A, member of RAS oncogene family 0.262
ESR1 estrogen receptor 1 0.254
GRID2 glutamate receptor, ionotropic, delta 2 0.251
BAD BCL2-associated agonist of cell death 0.250
ADORA2A adenosine A2a receptor 0.249
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.241
BSN bassoon (presynaptic cytomatrix protein) 0.231
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.230
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.229
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.221
SNAP23 synaptosomal-associated protein, 23kDa 0.217
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.216
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.215
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.215
DNM2 dynamin 2 0.213
WASF2 WAS protein family, member 2 0.211
SNAI1 snail homolog 1 (Drosophila) 0.207
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.201
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Mus musculus
Name Description Probability Func Analog Organism
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 1.000
Dlg4 discs, large homolog 4 (Drosophila) 1.000
Emx1 empty spiracles homolog 1 (Drosophila) 1.000
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 1.000
Nos1 nitric oxide synthase 1, neuronal 0.999
Bdnf brain derived neurotrophic factor 0.999
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.997
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.996
Drd2 dopamine receptor D2 0.996
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) 0.994
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.992
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.989
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.981
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.979
Prkce protein kinase C, epsilon 0.975
Snap25 synaptosomal-associated protein 25 0.973
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.968
Cacng2 calcium channel, voltage-dependent, gamma subunit 2 0.951
Grm1 glutamate receptor, metabotropic 1 0.951
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.938
Cit citron 0.935
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.932
Stx1a syntaxin 1A (brain) 0.927
Neurod1 neurogenic differentiation 1 0.921
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.917
Pax6 paired box gene 6 0.912
Bsn bassoon 0.909
Prkcc protein kinase C, gamma 0.907
Dab1 disabled homolog 1 (Drosophila) 0.900
Dlg2 discs, large homolog 2 (Drosophila) 0.897
Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) 0.889
Ina internexin neuronal intermediate filament protein, alpha 0.884
Srcin1 SRC kinase signaling inhibitor 1 0.872
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.868
Mtap2 microtubule-associated protein 2 0.852
Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) 0.823
Wnt7a wingless-related MMTV integration site 7A 0.817
Homer1 homer homolog 1 (Drosophila) 0.816
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.814
Syt2 synaptotagmin II 0.804
Psen1 presenilin 1 0.802
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.800
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.794
Adrb1 adrenergic receptor, beta 1 0.783
Camk2b calcium/calmodulin-dependent protein kinase II, beta 0.771
Ctnnb1 catenin (cadherin associated protein), beta 1 0.759
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.731
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.730
Ptgs2 prostaglandin-endoperoxide synthase 2 0.728
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.725
Plcb1 phospholipase C, beta 1 0.711
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 0.710
Rims2 regulating synaptic membrane exocytosis 2 0.709
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.709
Shank2 SH3/ankyrin domain gene 2 0.675
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.671
Crhr1 corticotropin releasing hormone receptor 1 0.664
Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 0.663
Syt1 synaptotagmin I 0.660
Plcg1 phospholipase C, gamma 1 0.651
Hoxb1 homeobox B1 0.645
Adcy1 adenylate cyclase 1 0.622
Nefl neurofilament, light polypeptide 0.619
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.616
Glra1 glycine receptor, alpha 1 subunit 0.606
Kcnc4 potassium voltage gated channel, Shaw-related subfamily, member 4 0.601
Ncan neurocan 0.596
Arc activity regulated cytoskeletal-associated protein 0.590
Vamp2 vesicle-associated membrane protein 2 0.590
Syp synaptophysin 0.582
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.581
Neurl1a neuralized homolog 1A (Drosophila) 0.568
S100a9 S100 calcium binding protein A9 (calgranulin B) 0.552
Grid1 glutamate receptor, ionotropic, delta 1 0.550
Kcns2 K+ voltage-gated channel, subfamily S, 2 0.549
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.547
Shc3 src homology 2 domain-containing transforming protein C3 0.538
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.537
Drd1a dopamine receptor D1A 0.526
Gabra2 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 0.525
Nsf N-ethylmaleimide sensitive fusion protein 0.523
Ptpn5 protein tyrosine phosphatase, non-receptor type 5 0.518
Sez6l seizure related 6 homolog like 0.517
S100a13 S100 calcium binding protein A13 0.516
Mmp24 matrix metallopeptidase 24 0.507
Des desmin 0.497
Cbln1 cerebellin 1 precursor protein 0.496
Dcx doublecortin 0.489
Grin2d glutamate receptor, ionotropic, NMDA2D (epsilon 4) 0.489
Ptk2 PTK2 protein tyrosine kinase 2 0.479
Sult4a1 sulfotransferase family 4A, member 1 0.462
Mapk10 mitogen-activated protein kinase 10 0.462
Adra2c adrenergic receptor, alpha 2c 0.446
Stx1b syntaxin 1B 0.444
Nrg3 neuregulin 3 0.437
Ncam2 neural cell adhesion molecule 2 0.425
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.419
Nptx1 neuronal pentraxin 1 0.415
Neto1 neuropilin (NRP) and tolloid (TLL)-like 1 0.414
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.403
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism