Process View
The network for 'i kappab kinase nf kappab signaling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.034 | |
Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.032 | |
Cdk4 | cyclin-dependent kinase 4 | 0.032 | |
Tpm3 | tropomyosin 3, gamma | 0.029 | |
Ccl4 | chemokine (C-C motif) ligand 4 | 0.029 | |
Icam1 | intercellular adhesion molecule 1 | 0.025 | |
Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.023 | |
LOC100365106 | rCG32755-like | 0.023 | |
Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.023 | |
Il6 | interleukin 6 | 0.023 | |
Cd86 | CD86 molecule | 0.020 | |
Shisa5 | shisa homolog 5 (Xenopus laevis) | 0.020 | |
Irf1 | interferon regulatory factor 1 | 0.019 | |
Slfn2 | schlafen 2 | 0.019 | |
Rad23b | RAD23 homolog B (S. cerevisiae) | 0.019 | |
Ccl2 | chemokine (C-C motif) ligand 2 | 0.018 | |
Stat6 | signal transducer and activator of transcription 6 | 0.018 | |
Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.017 | |
LOC100362108 | poly (ADP-ribose) polymerase family, member 10 | 0.017 | |
Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.016 | |
Pla2g4a | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.016 | |
Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.016 | |
LOC686326 | similar to Interferon-alpha/beta receptor beta chain precursor (IFN-alpha-REC) (Type I interferon receptor) (IFN-R) (Interferon alpha/beta receptor-2) | 0.015 | |
Apol3 | apolipoprotein L, 3 | 0.015 | |
Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.015 | |
Il1b | interleukin 1 beta | 0.015 | |
LOC100363783 | rCG53773-like | 0.015 | |
Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.015 | |
Syngr2 | synaptogyrin 2 | 0.014 | |
Kcnj8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.014 | |
Hist1h1a | histone cluster 1, H1a | 0.014 | |
Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.014 | |
Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.014 | |
Timp1 | TIMP metallopeptidase inhibitor 1 | 0.013 | |
Usf2 | upstream transcription factor 2, c-fos interacting | 0.013 | |
Tnks2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.013 | |
Mca32 | mast cell antigen 32 | 0.012 | |
Gbp2 | guanylate binding protein 2 | 0.012 | |
Stat3 | signal transducer and activator of transcription 3 | 0.012 | |
Birc3 | baculoviral IAP repeat-containing 3 | 0.012 | |
Il1a | interleukin 1 alpha | 0.012 | |
Sgta | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.012 | |
Vdac1 | voltage-dependent anion channel 1 | 0.012 | |
Svs3a | seminal vesicle secretory protein 3A | 0.012 | |
Papd5 | PAP associated domain containing 5 | 0.011 | |
Cap1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.011 | |
Zyx | zyxin | 0.011 | |
Dtx3l | deltex 3-like (Drosophila) | 0.011 | |
Il2rg | interleukin 2 receptor, gamma | 0.011 | |
Notch1 | Notch homolog 1, translocation-associated (Drosophila) | 0.011 | |
Myh9 | myosin, heavy chain 9, non-muscle | 0.011 | |
Traf6 | Tnf receptor-associated factor 6 | 0.010 | |
Tmed10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.010 | |
Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.010 | |
Sp140 | SP140 nuclear body protein | 0.010 | |
Igtp | interferon gamma induced GTPase | 0.010 | |
Serinc5 | serine incorporator 5 | 0.010 | |
Stat1 | signal transducer and activator of transcription 1 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
nfkbiaa | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a | 0.885 | |
nod1 | nucleotide-binding oligomerization domain containing 1 | 0.715 | |
tgm2b | transglutaminase 2b | 0.584 | |
klfd | Kruppel-like factor d | 0.505 | |
cav1 | caveolin 1 | 0.498 | |
tlr3 | toll-like receptor 3 | 0.390 | |
csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.381 | |
caspa | caspase a | 0.375 | |
slc15a2 | solute carrier family 15 (H+/peptide transporter), member 2 | 0.306 | |
mmp9 | matrix metalloproteinase 9 | 0.291 | |
vcanb | versican b | 0.279 | |
itm2bb | integral membrane protein 2Bb | 0.259 | |
nccrp1 | nonspecific cytotoxic cell receptor protein 1 | 0.258 | |
tph2 | tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) | 0.258 | |
ip6k2 | inositol hexaphosphate kinase 2 | 0.243 | |
hcrt | hypocretin (orexin) neuropeptide precursor | 0.228 | |
cdc42 | cell division cycle 42 | 0.226 | |
junb | jun B proto-oncogene | 0.225 | |
serpinb1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.216 | |
wasb | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b | 0.205 | |
socs3a | suppressor of cytokine signaling 3a | 0.203 | |
pbx4 | pre-B-cell leukemia transcription factor 4 | 0.201 | |
b2m | beta-2-microglobulin | 0.199 | |
adipor1b | adiponectin receptor 1b | 0.197 | |
ptenb | phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) | 0.190 | |
si:ch211-9d9.3 | si:ch211-9d9.3 | 0.189 | |
kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.183 | |
tlr9 | toll-like receptor 9 | 0.172 | |
tlr2 | toll-like receptor 2 | 0.171 | |
hbbe1.1 | hemoglobin beta embryonic-1.1 | 0.170 | |
stat1a | signal transduction and activation of transcription 1a | 0.163 | |
LOC100003514 | protein kinase C alpha type-like | 0.163 | |
tsen54 | tRNA splicing endonuclease 54 homolog (S. cerevisiae) | 0.162 | |
irf9 | interferon regulatory factor 9 | 0.160 | |
metap2 | methionyl aminopeptidase 2 | 0.158 | |
dll4 | delta-like 4 (Drosophila) | 0.158 | |
nr3c1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.157 | |
wls | wntless homolog (Drosophila) | 0.153 | |
prkcz | protein kinase C, zeta | 0.153 | |
jun | jun proto-oncogene | 0.149 | |
pdcd6ip | programmed cell death 6 interacting protein | 0.148 | |
brd2b | bromodomain containing 2b | 0.146 | |
atf3 | activating transcription factor 3 | 0.146 | |
rhag | Rhesus blood group-associated glycoprotein | 0.141 | |
acp5b | acid phosphatase 5b, tartrate resistant | 0.141 | |
adipor2 | adiponectin receptor 2 | 0.139 | |
hbaa1 | hemoglobin alpha adult-1 | 0.139 | |
gadd45ba | growth arrest and DNA-damage-inducible, beta a | 0.134 | |
adipoql | adiponectin, C1Q and collagen domain containing, like | 0.128 | |
zgc:153997 | zgc:153997 | 0.126 | |
LOC100000934 | hypothetical protein LOC100000934 | 0.125 | |
foxo3b | forkhead box O3b | 0.125 | |
wnt3 | wingless-type MMTV integration site family, member 3 | 0.123 | |
coro1a | coronin, actin binding protein, 1A | 0.122 | |
cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.120 | |
cd63 | Cd63 antigen | 0.119 | |
grna | granulin a | 0.118 | |
cbr1l | carbonyl reductase 1-like | 0.117 | |
zgc:92027 | zgc:92027 | 0.117 | |
fancd2 | Fanconi anemia, complementation group D2 | 0.116 | |
fos | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0.116 | |
il8 | interleukin 8 | 0.116 | |
tnfb | tumor necrosis factor b (TNF superfamily, member 2) | 0.115 | |
myd88 | myeloid differentiation primary response gene (88) | 0.115 | |
per3 | period homolog 3 (Drosophila) | 0.112 | |
slc4a1b | solute carrier family 4, anion exchanger, member 1b | 0.112 | |
tmed2 | transmembrane emp24 domain trafficking protein 2 | 0.111 | |
angptl1 | angiopoietin-like 1 | 0.109 | |
wasa | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a | 0.109 | |
grifin | galectin related inter-fiber protein | 0.108 | |
f2rl1.2 | coagulation factor II (thrombin) receptor-like 1.2 | 0.108 | |
btk | Bruton agammaglobulinemia tyrosine kinase | 0.108 | |
zgc:101614 | zgc:101614 | 0.107 | |
icn | ictacalcin | 0.106 | |
mmp15b | matrix metallopeptidase 15b | 0.103 | |
gng5 | guanine nucleotide binding protein (G protein), gamma 5 | 0.102 | |
ppp4ca | protein phosphatase 4 (formerly X), catalytic subunit a | 0.102 | |
si:dkeyp-22b2.3 | si:dkeyp-22b2.3 | 0.102 | |
elovl4a | elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a | 0.102 | |
si:dkey-8l13.4 | si:dkey-8l13.4 | 0.102 | |
pycard | PYD and CARD domain containing | 0.101 | |
epb41 | erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) | 0.101 | |
chuk | conserved helix-loop-helix ubiquitous kinase | 0.101 | |
gnat2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 | 0.100 | |
LOC100003330 | melanocortin-2 receptor accessory protein 2-like | 0.098 | |
tm4sf4 | transmembrane 4 L six family member 4 | 0.098 | |
trpv6 | transient receptor potential cation channel, subfamily V, member 6 | 0.097 | |
epo | erythropoietin | 0.096 | |
cps1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.095 | |
adrb2a | adrenergic receptor, beta 2a | 0.093 | |
tlr18 | toll-like receptor 18 | 0.093 | |
wnt2bb | wingless-type MMTV integration site family, member 2Bb | 0.091 | |
otc | ornithine carbamoyltransferase | 0.091 | |
per2 | period homolog 2 (Drosophila) | 0.091 | |
ube2nb | ubiquitin-conjugating enzyme E2Nb | 0.090 | |
zgc:136759 | zgc:136759 | 0.090 | |
rbm22 | RNA binding motif protein 22 | 0.089 | |
blvrb | biliverdin reductase B (flavin reductase (NADPH)) | 0.088 | |
litaf | lipopolysaccharide-induced TNF factor | 0.087 | |
mipa | major intrinsic protein of lens fiber a | 0.084 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Tl | Toll | 0.274 | |
l(2)gl | lethal (2) giant larvae | 0.253 | |
Hsp27 | Heat shock protein 27 | 0.090 | |
Tak1 | TGF-beta activated kinase 1 | 0.072 | |
Myd88 | CG2078 gene product from transcript CG2078-RA | 0.061 | |
ird5 | immune response deficient 5 | 0.058 | |
brat | brain tumor | 0.056 | |
hep | hemipterous | 0.055 | |
Akt1 | CG4006 gene product from transcript CG4006-RA | 0.053 | |
BG4 | CG12297 gene product from transcript CG12297-RA | 0.043 | |
arm | armadillo | 0.039 | |
pum | pumilio | 0.035 | |
Rac1 | CG2248 gene product from transcript CG2248-RA | 0.029 | |
imd | immune deficiency | 0.026 | |
ftz-f1 | ftz transcription factor 1 | 0.024 | |
dsh | dishevelled | 0.018 | |
inaD | inactivation no afterpotential D | 0.018 | |
Dcr-2 | Dicer-2 | 0.017 | |
18w | 18 wheeler | 0.017 | |
Pli | Pellino | 0.017 | |
spz | spatzle | 0.017 | |
p24-1 | p24-related-1 | 0.016 | |
aop | anterior open | 0.016 | |
bai | baiser | 0.015 | |
Mad | Mothers against dpp | 0.014 | |
Psn | Presenilin | 0.014 | |
dia | diaphanous | 0.014 | |
Vap-33-1 | CG5014 gene product from transcript CG5014-RB | 0.013 | |
eca | eclair | 0.013 | |
Ptp69D | Protein tyrosine phosphatase 69D | 0.013 | |
lwr | lesswright | 0.012 | |
key | kenny | 0.012 | |
Cat | Catalase | 0.011 | |
Akap200 | A kinase anchor protein 200 | 0.011 | |
egg | eggless | 0.010 | |
Rel | Relish | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 1.000 | |
TRAF6 | TNF receptor-associated factor 6 | 1.000 | |
TRAF2 | TNF receptor-associated factor 2 | 1.000 | |
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 1.000 | |
BIRC3 | baculoviral IAP repeat containing 3 | 1.000 | |
XIAP | X-linked inhibitor of apoptosis | 1.000 | |
RIPK2 | receptor-interacting serine-threonine kinase 2 | 1.000 | |
UBC | ubiquitin C | 1.000 | |
CASP8 | caspase 8, apoptosis-related cysteine peptidase | 1.000 | |
MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 1.000 | |
SQSTM1 | sequestosome 1 | 1.000 | |
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 1.000 | |
TRAF1 | TNF receptor-associated factor 1 | 1.000 | |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 1.000 | |
TRAF3 | TNF receptor-associated factor 3 | 1.000 | |
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.999 | |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.998 | |
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.998 | |
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.996 | |
TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.994 | |
CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.994 | |
MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.993 | |
FLNA | filamin A, alpha | 0.993 | |
UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.992 | |
MYD88 | myeloid differentiation primary response gene (88) | 0.992 | |
UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.990 | |
RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.990 | |
TRADD | TNFRSF1A-associated via death domain | 0.988 | |
IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.988 | |
MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.980 | |
TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.980 | |
TNIP2 | TNFAIP3 interacting protein 2 | 0.978 | |
CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.977 | |
BIRC2 | baculoviral IAP repeat containing 2 | 0.976 | |
CFLAR | CASP8 and FADD-like apoptosis regulator | 0.974 | |
S100A6 | S100 calcium binding protein A6 | 0.973 | |
SMAD3 | SMAD family member 3 | 0.973 | |
FAS | Fas (TNF receptor superfamily, member 6) | 0.971 | |
ESR1 | estrogen receptor 1 | 0.964 | |
IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.964 | |
CHUK | conserved helix-loop-helix ubiquitous kinase | 0.961 | |
CARD11 | caspase recruitment domain family, member 11 | 0.956 | |
IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.954 | |
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.951 | |
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.947 | |
FADD | Fas (TNFRSF6)-associated via death domain | 0.944 | |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.939 | |
IL1B | interleukin 1, beta | 0.933 | |
CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.924 | |
JAG1 | jagged 1 | 0.903 | |
TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.888 | |
ZNF43 | zinc finger protein 43 | 0.888 | |
TNF | tumor necrosis factor | 0.884 | |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.882 | |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.875 | |
NOTCH1 | notch 1 | 0.871 | |
DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.869 | |
RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.867 | |
CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.867 | |
CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.864 | |
MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.861 | |
IL1R1 | interleukin 1 receptor, type I | 0.850 | |
ZNF675 | zinc finger protein 675 | 0.846 | |
HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.840 | |
IRF1 | interferon regulatory factor 1 | 0.836 | |
TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.834 | |
S100B | S100 calcium binding protein B | 0.821 | |
TP53 | tumor protein p53 | 0.806 | |
CCL4 | chemokine (C-C motif) ligand 4 | 0.792 | |
PML | promyelocytic leukemia | 0.790 | |
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.765 | |
MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.751 | |
S100A9 | S100 calcium binding protein A9 | 0.738 | |
S100A8 | S100 calcium binding protein A8 | 0.726 | |
TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.715 | |
TNIP1 | TNFAIP3 interacting protein 1 | 0.712 | |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.704 | |
IL8 | interleukin 8 | 0.699 | |
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.693 | |
S100A16 | S100 calcium binding protein A16 | 0.676 | |
ANXA1 | annexin A1 | 0.673 | |
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.656 | |
S100A14 | S100 calcium binding protein A14 | 0.654 | |
SFN | stratifin | 0.648 | |
MYH9 | myosin, heavy chain 9, non-muscle | 0.645 | |
ANXA2 | annexin A2 | 0.640 | |
NLRC4 | NLR family, CARD domain containing 4 | 0.632 | |
BCL3 | B-cell CLL/lymphoma 3 | 0.615 | |
ARRB1 | arrestin, beta 1 | 0.612 | |
CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.612 | |
ZNF253 | zinc finger protein 253 | 0.612 | |
TRAF5 | TNF receptor-associated factor 5 | 0.609 | |
BCL10 | B-cell CLL/lymphoma 10 | 0.602 | |
TICAM2 | toll-like receptor adaptor molecule 2 | 0.602 | |
TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.580 | |
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.577 | |
S100A4 | S100 calcium binding protein A4 | 0.576 | |
LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.574 | |
PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.565 | |
PSEN1 | presenilin 1 | 0.559 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Tlr4 | toll-like receptor 4 | 1.000 | |
Tnf | tumor necrosis factor | 1.000 | |
Myd88 | myeloid differentiation primary response gene 88 | 1.000 | |
Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 1.000 | |
Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 1.000 | |
Traf6 | TNF receptor-associated factor 6 | 1.000 | |
Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.999 | |
Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.999 | |
Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.999 | |
Casp1 | caspase 1 | 0.999 | |
Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.999 | |
Ikbkg | inhibitor of kappaB kinase gamma | 0.999 | |
Il1r1 | interleukin 1 receptor, type I | 0.998 | |
Lyz2 | lysozyme 2 | 0.998 | |
Cd44 | CD44 antigen | 0.994 | |
Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.989 | |
Lta | lymphotoxin A | 0.985 | |
Ticam1 | toll-like receptor adaptor molecule 1 | 0.985 | |
Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.984 | |
Cd40 | CD40 antigen | 0.978 | |
Ccl2 | chemokine (C-C motif) ligand 2 | 0.973 | |
Ikbkb | inhibitor of kappaB kinase beta | 0.970 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.968 | |
Casp8 | caspase 8 | 0.961 | |
Birc3 | baculoviral IAP repeat-containing 3 | 0.950 | |
Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.946 | |
Fas | Fas (TNF receptor superfamily member 6) | 0.944 | |
Ikzf1 | IKAROS family zinc finger 1 | 0.929 | |
Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.929 | |
Cd19 | CD19 antigen | 0.926 | |
Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.922 | |
Cd28 | CD28 antigen | 0.874 | |
Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.865 | |
Il1b | interleukin 1 beta | 0.856 | |
Stat3 | signal transducer and activator of transcription 3 | 0.845 | |
Bcl3 | B-cell leukemia/lymphoma 3 | 0.824 | |
Hif1a | hypoxia inducible factor 1, alpha subunit | 0.811 | |
S100a6 | S100 calcium binding protein A6 (calcyclin) | 0.808 | |
Cyld | cylindromatosis (turban tumor syndrome) | 0.805 | |
Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.795 | |
Pim1 | proviral integration site 1 | 0.791 | |
Clec4d | C-type lectin domain family 4, member d | 0.746 | |
Pten | phosphatase and tensin homolog | 0.744 | |
Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.743 | |
Tbk1 | TANK-binding kinase 1 | 0.732 | |
Clec4e | C-type lectin domain family 4, member e | 0.720 | |
Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.715 | |
Cd14 | CD14 antigen | 0.698 | |
Il10 | interleukin 10 | 0.679 | |
Ifng | interferon gamma | 0.672 | |
Casp12 | caspase 12 | 0.656 | |
Nlrp3 | NLR family, pyrin domain containing 3 | 0.655 | |
Il18rap | interleukin 18 receptor accessory protein | 0.650 | |
Traf2 | TNF receptor-associated factor 2 | 0.649 | |
Il7 | interleukin 7 | 0.617 | |
Icos | inducible T-cell co-stimulator | 0.613 | |
Socs1 | suppressor of cytokine signaling 1 | 0.608 | |
Chuk | conserved helix-loop-helix ubiquitous kinase | 0.606 | |
Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.571 | |
Ptprc | protein tyrosine phosphatase, receptor type, C | 0.529 | |
Ptk2 | PTK2 protein tyrosine kinase 2 | 0.526 | |
Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.521 | |
Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.507 | |
Zfp36 | zinc finger protein 36 | 0.506 | |
Ifnar1 | interferon (alpha and beta) receptor 1 | 0.505 | |
Irf1 | interferon regulatory factor 1 | 0.500 | |
Il6 | interleukin 6 | 0.484 | |
Il1rn | interleukin 1 receptor antagonist | 0.480 | |
Ccr6 | chemokine (C-C motif) receptor 6 | 0.479 | |
Kiss1 | KiSS-1 metastasis-suppressor | 0.477 | |
Sqstm1 | sequestosome 1 | 0.457 | |
Ltb | lymphotoxin B | 0.453 | |
Ccr1 | chemokine (C-C motif) receptor 1 | 0.447 | |
Rnf31 | ring finger protein 31 | 0.442 | |
Cd86 | CD86 antigen | 0.442 | |
Tcra | T-cell receptor alpha chain | 0.438 | |
Il2rg | interleukin 2 receptor, gamma chain | 0.436 | |
Mll5 | myeloid/lymphoid or mixed-lineage leukemia 5 | 0.430 | |
Edaradd | EDAR (ectodysplasin-A receptor)-associated death domain | 0.413 | |
Pxn | paxillin | 0.412 | |
Mavs | mitochondrial antiviral signaling protein | 0.411 | |
Clec4n | C-type lectin domain family 4, member n | 0.409 | |
Tnip1 | TNFAIP3 interacting protein 1 | 0.406 | |
Traf3 | TNF receptor-associated factor 3 | 0.406 | |
Csf1 | colony stimulating factor 1 (macrophage) | 0.405 | |
Tlr2 | toll-like receptor 2 | 0.401 | |
Slfn4 | schlafen 4 | 0.392 | |
Unc93b1 | unc-93 homolog B1 (C. elegans) | 0.389 | |
Il2rb | interleukin 2 receptor, beta chain | 0.382 | |
Mvp | major vault protein | 0.381 | |
Ubc | ubiquitin C | 0.380 | |
Notch1 | Notch gene homolog 1 (Drosophila) | 0.371 | |
Cav1 | caveolin 1, caveolae protein | 0.363 | |
Trim21 | tripartite motif-containing 21 | 0.357 | |
Dok1 | docking protein 1 | 0.354 | |
Gbp5 | guanylate binding protein 5 | 0.354 | |
Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.352 | |
Nfkbiz | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.350 | |
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.347 | |
Vim | vimentin | 0.340 |