The network for 'acid secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

acid secretion

The controlled release of acid by a cell or a tissue.

Rattus norvegicus
Name Description Probability Func Analog Organism
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.521
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.503
Sstr5 somatostatin receptor 5 0.468
Ctsj cathepsin J 0.366
Mep1b meprin 1 beta 0.350
Adam2 ADAM metallopeptidase domain 2 0.347
Bcan brevican 0.288
Kcnj16 potassium inwardly-rectifying channel, subfamily J, member 16 0.264
Grik1 glutamate receptor, ionotropic, kainate 1 0.251
Psp parotid secretory protein 0.240
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.232
Vip vasoactive intestinal peptide 0.232
Edn2 endothelin 2 0.228
Nmbr neuromedin B receptor 0.225
Scn10a sodium channel, voltage-gated, type X, alpha subunit 0.220
Th tyrosine hydroxylase 0.215
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.214
Mag myelin-associated glycoprotein 0.214
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.212
Akr1c18 aldo-keto reductase family 1, member C18 0.206
Slc13a2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 0.203
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.202
Avpr2 arginine vasopressin receptor 2 0.200
Impg2 interphotoreceptor matrix proteoglycan 2 0.194
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.190
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.187
Ush1c Usher syndrome 1C homolog (human) 0.178
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.172
Kl Klotho 0.167
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.165
Adora1 adenosine A1 receptor 0.162
Fgf14 fibroblast growth factor 14 0.162
Pomc proopiomelanocortin 0.162
Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 0.161
Grm7 glutamate receptor, metabotropic 7 0.160
Avp arginine vasopressin 0.158
Chrna3 cholinergic receptor, nicotinic, alpha 3 0.156
Nfasc neurofascin 0.155
Syt4 synaptotagmin IV 0.153
Barhl2 BarH-like homeobox 2 0.151
Gad2 glutamate decarboxylase 2 0.149
Pitx3 paired-like homeodomain 3 0.149
Htr3a 5-hydroxytryptamine (serotonin) receptor 3a 0.144
Olr287 olfactory receptor 287 0.144
Trhr thyrotropin releasing hormone receptor 0.143
Sorcs3 sortilin-related VPS10 domain containing receptor 3 0.140
Mog myelin oligodendrocyte glycoprotein 0.138
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.137
Gjb4 gap junction protein, beta 4 0.137
Chrm1 cholinergic receptor, muscarinic 1 0.135
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.133
Pcdhb12 protocadherin beta 12 0.133
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.132
Pla2g5 phospholipase A2, group V 0.132
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.128
Lim2 lens intrinsic membrane protein 2 0.128
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.126
Tshb thyroid stimulating hormone, beta 0.125
Slc22a25 solute carrier family 22, member 25 0.122
Crhr1 corticotropin releasing hormone receptor 1 0.121
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.120
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.119
Olr1361 olfactory receptor 1361 0.117
Cckbr cholecystokinin B receptor 0.117
Calca calcitonin-related polypeptide alpha 0.111
Grk1 G protein-coupled receptor kinase 1 0.109
Htr4 5-hydroxytryptamine (serotonin) receptor 4 0.107
Hpcal4 hippocalcin-like 4 0.105
Olr1346 olfactory receptor 1346 0.101
Prlr prolactin receptor 0.101
Nlgn3 neuroligin 3 0.099
Cnga1 cyclic nucleotide gated channel alpha 1 0.098
Calcr calcitonin receptor 0.098
Catsper2 cation channel, sperm associated 2 0.098
Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 0.097
Nrg1 neuregulin 1 0.097
Ppp2r2c protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform 0.095
Gfap glial fibrillary acidic protein 0.095
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.094
Fxyd4 FXYD domain-containing ion transport regulator 4 0.092
Prkcg protein kinase C, gamma 0.092
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.091
Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 0.090
Slc32a1 solute carrier family 32 (GABA vesicular transporter), member 1 0.090
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.090
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.088
Csf3 colony stimulating factor 3 (granulocyte) 0.087
Hrh4 histamine receptor H4 0.087
Grid1 glutamate receptor, ionotropic, delta 1 0.086
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.086
Olr226 olfactory receptor 226 0.086
Glra1 glycine receptor, alpha 1 0.086
Sncb synuclein, beta 0.086
Plcd4 phospholipase C, delta 4 0.085
B3gat1 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) 0.084
Myt1l myelin transcription factor 1-like 0.083
Scn3a sodium channel, voltage-gated, type III, alpha 0.082
Mmp10 matrix metallopeptidase 10 0.082
Folh1 folate hydrolase 1 0.081
Faim2 Fas apoptotic inhibitory molecule 2 0.081
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Gr28b Gustatory receptor 28b 0.109
mtt mangetout 0.102
Cyp316a1 CG8540 gene product from transcript CG8540-RA 0.100
Chc Clathrin heavy chain 0.057
inaD inactivation no afterpotential D 0.050
Stam Signal transducing adaptor molecule 0.042
Ace Acetylcholine esterase 0.038
trp transient receptor potential 0.037
CG2736 CG2736 gene product from transcript CG2736-RA 0.037
CG6910 CG6910 gene product from transcript CG6910-RB 0.035
Or22a Odorant receptor 22a 0.033
CG32556 CG32556 gene product from transcript CG32556-RB 0.033
PEK pancreatic eIF-2alpha kinase 0.032
CG42629 CG42629 gene product from transcript CG42629-RB 0.031
Clk Clock 0.031
CG4822 CG4822 gene product from transcript CG4822-RB 0.030
CG5758 CG5758 gene product from transcript CG5758-RC 0.029
CG3376 CG3376 gene product from transcript CG3376-RB 0.028
JhI-21 CG12317 gene product from transcript CG12317-RB 0.027
DJ-1alpha CG6646 gene product from transcript CG6646-RA 0.027
CG6051 CG6051 gene product from transcript CG6051-RB 0.026
Karybeta3 Karyopherin beta 3 0.024
CG33120 CG33120 gene product from transcript CG33120-RA 0.024
CG3714 CG3714 gene product from transcript CG3714-RC 0.024
CG1092 CG1092 gene product from transcript CG1092-RA 0.023
ppk25 pickpocket 25 0.023
tim timeless 0.023
Gel Gelsolin 0.023
Arr2 Arrestin 2 0.022
scat scattered 0.022
Gr32a Gustatory receptor 32a 0.022
CG7781 CG7781 gene product from transcript CG7781-RA 0.021
Idgf5 Imaginal disc growth factor 5 0.021
trpl trp-like 0.021
Gr43a Gustatory receptor 43a 0.021
Tre Trehalose-sensitivity 0.020
MP1 Melanization Protease 1 0.020
comt comatose 0.020
CG32185 CG32185 gene product from transcript CG32185-RA 0.020
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.020
Rh6 Rhodopsin 6 0.019
CG1468 CG1468 gene product from transcript CG1468-RA 0.019
Adar Adenosine deaminase acting on RNA 0.019
ras raspberry 0.019
norpA no receptor potential A 0.019
CG17134 CG17134 gene product from transcript CG17134-RA 0.019
Csas CMP-sialic acid synthase 0.019
ninaC neither inactivation nor afterpotential C 0.019
CG15080 CG15080 gene product from transcript CG15080-RA 0.019
Gr39a Gustatory receptor 39a 0.019
CG7079 CG7079 gene product from transcript CG7079-RA 0.019
CG14945 CG14945 gene product from transcript CG14945-RB 0.019
HSPC300 CG30173 gene product from transcript CG30173-RA 0.019
RASSF8 CG5053 gene product from transcript CG5053-RA 0.019
CG14526 CG14526 gene product from transcript CG14526-RB 0.018
CG12004 CG12004 gene product from transcript CG12004-RC 0.018
CG6509 CG6509 gene product from transcript CG6509-RB 0.018
bdg bedraggled 0.018
beta4GalNAcTA CG8536 gene product from transcript CG8536-RA 0.018
CG13795 CG13795 gene product from transcript CG13795-RB 0.018
CG10413 CG10413 gene product from transcript CG10413-RA 0.018
Snap Soluble NSF attachment protein 0.018
CG5789 CG5789 gene product from transcript CG5789-RA 0.017
CG5945 CG5945 gene product from transcript CG5945-RA 0.017
ana anachronism 0.017
inaF-D CG42563 gene product from transcript CG42563-RB 0.017
lox2 lysyl oxidase-like 2 0.017
CG33307 CG33307 gene product from transcript CG33307-RA 0.017
Oatp74D Organic anion transporting polypeptide 74D 0.017
Ca-alpha1T CG15899 gene product from transcript CG15899-RC 0.017
5-HT1A Serotonin receptor 1A 0.016
CG14085 CG14085 gene product from transcript CG14085-RA 0.016
Fhos CG42610 gene product from transcript CG42610-RC 0.016
ninaB neither inactivation nor afterpotential B 0.016
c11.1 CG12132 gene product from transcript CG12132-RA 0.016
CG10799 CG10799 gene product from transcript CG10799-RA 0.016
Nep4 Neprilysin 4 0.016
Tsp5D Tetraspanin 5D 0.016
Rh3 Rhodopsin 3 0.016
JhI-1 Juvenile hormone-inducible protein 1 0.016
CG1998 CG1998 gene product from transcript CG1998-RA 0.016
Galpha49B G protein alpha49B 0.016
unc79 CG5237 gene product from transcript CG5237-RB 0.016
Vsx2 CG33980 gene product from transcript CG33980-RA 0.015
PIP82 CG11219 gene product from transcript CG11219-RA 0.015
alpha-Est1 alpha-Esterase-1 0.015
CG33214 CG33214 gene product from transcript CG33214-RA 0.015
CG42369 CG42369 gene product from transcript CG42369-RA 0.015
CG4721 CG4721 gene product from transcript CG4721-RA 0.015
ppk6 pickpocket 6 0.015
DopR Dopamine receptor 0.015
Cyp313a1 CG3360 gene product from transcript CG3360-RA 0.015
CG6959 CG6959 gene product from transcript CG6959-RA 0.015
CG9650 CG9650 gene product from transcript CG9650-RG 0.015
nimB5 nimrod B5 0.015
CG3164 CG3164 gene product from transcript CG3164-RA 0.015
CG32444 CG32444 gene product from transcript CG32444-RA 0.015
CG13933 CG13933 gene product from transcript CG13933-RA 0.014
5-HT7 Serotonin receptor 7 0.014
ST6Gal Sialyltransferase 0.014
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Homo sapiens
Name Description Probability Func Analog Organism
DRD2 dopamine receptor D2 0.883
IL1R1 interleukin 1 receptor, type I 0.814
KCNE1 potassium voltage-gated channel, Isk-related family, member 1 0.610
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.564
ADORA2A adenosine A2a receptor 0.481
RLN3 relaxin 3 0.250
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.234
TPBG trophoblast glycoprotein 0.176
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.167
MAPK14 mitogen-activated protein kinase 14 0.149
SLC6A3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.147
MAPT microtubule-associated protein tau 0.127
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.125
IL1R2 interleukin 1 receptor, type II 0.075
LRRK2 leucine-rich repeat kinase 2 0.070
APP amyloid beta (A4) precursor protein 0.064
MAP2K4 mitogen-activated protein kinase kinase 4 0.050
DLG4 discs, large homolog 4 (Drosophila) 0.045
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.040
TBC1D10A TBC1 domain family, member 10A 0.039
IL1RAP interleukin 1 receptor accessory protein 0.033
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.031
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.031
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.029
ADORA1 adenosine A1 receptor 0.023
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.021
BDKRB2 bradykinin receptor B2 0.020
TYRP1 tyrosinase-related protein 1 0.020
NECAB2 N-terminal EF-hand calcium binding protein 2 0.018
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.018
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.018
C1orf93 chromosome 1 open reading frame 93 0.016
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.016
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.015
NAMPT nicotinamide phosphoribosyltransferase 0.015
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.014
SLC34A1 solute carrier family 34 (sodium phosphate), member 1 0.014
ADRB2 adrenergic, beta-2-, receptor, surface 0.013
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.013
ANXA5 annexin A5 0.013
FYN FYN oncogene related to SRC, FGR, YES 0.012
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.012
GFRA4 GDNF family receptor alpha 4 0.012
CHRNA4 cholinergic receptor, nicotinic, alpha 4 0.012
RAX retina and anterior neural fold homeobox 0.011
NCR2 natural cytotoxicity triggering receptor 2 0.011
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 0.011
ARHGAP22 Rho GTPase activating protein 22 0.011
ARRB1 arrestin, beta 1 0.011
LPHN1 latrophilin 1 0.011
SNCAIP synuclein, alpha interacting protein 0.011
TPPP tubulin polymerization promoting protein 0.010
PDZK1 PDZ domain containing 1 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 1.000
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.953
Drd2 dopamine receptor D2 0.924
Lta lymphotoxin A 0.918
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.893
Npy2r neuropeptide Y receptor Y2 0.767
Npy1r neuropeptide Y receptor Y1 0.765
Cftr cystic fibrosis transmembrane conductance regulator homolog 0.690
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.669
Kl klotho 0.668
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.638
Dysf dysferlin 0.638
Tnf tumor necrosis factor 0.636
Ntf3 neurotrophin 3 0.612
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.603
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.599
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.544
Lep leptin 0.537
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.471
Crhr1 corticotropin releasing hormone receptor 1 0.459
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.455
Nos2 nitric oxide synthase 2, inducible 0.432
Cd40 CD40 antigen 0.419
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.418
Dlg4 discs, large homolog 4 (Drosophila) 0.392
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.389
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.376
Il12b interleukin 12b 0.352
Bdnf brain derived neurotrophic factor 0.350
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.339
S1pr2 sphingosine-1-phosphate receptor 2 0.334
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.330
Igh immunoglobulin heavy chain complex 0.325
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.321
Cryaa crystallin, alpha A 0.294
Grm2 glutamate receptor, metabotropic 2 0.273
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.270
Slc4a4 solute carrier family 4 (anion exchanger), member 4 0.268
Il1r1 interleukin 1 receptor, type I 0.228
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.220
Esr1 estrogen receptor 1 (alpha) 0.208
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) 0.201
Gal galanin 0.199
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.194
Oprm1 opioid receptor, mu 1 0.192
Nos1 nitric oxide synthase 1, neuronal 0.183
Pspn persephin 0.180
Nxph2 neurexophilin 2 0.168
Kcnh3 potassium voltage-gated channel, subfamily H (eag-related), member 3 0.166
Foxf2 forkhead box F2 0.158
Gdf15 growth differentiation factor 15 0.157
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.157
Hoxd13 homeobox D13 0.156
Plxna1 plexin A1 0.156
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.155
Gcgr glucagon receptor 0.150
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.147
Rasal1 RAS protein activator like 1 (GAP1 like) 0.140
Pde6a phosphodiesterase 6A, cGMP-specific, rod, alpha 0.138
Btk Bruton agammaglobulinemia tyrosine kinase 0.135
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.131
Kcnk4 potassium channel, subfamily K, member 4 0.131
Cnr1 cannabinoid receptor 1 (brain) 0.129
Cxcl13 chemokine (C-X-C motif) ligand 13 0.129
Ltb lymphotoxin B 0.128
Hrh2 histamine receptor H2 0.128
Syt10 synaptotagmin X 0.127
Itga2 integrin alpha 2 0.125
Grm1 glutamate receptor, metabotropic 1 0.123
Nrg1 neuregulin 1 0.120
Adora2a adenosine A2a receptor 0.119
Pnpla2 patatin-like phospholipase domain containing 2 0.118
Lhx9 LIM homeobox protein 9 0.116
ND6 NADH dehydrogenase subunit 6 0.114
Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 0.113
Slc5a11 solute carrier family 5 (sodium/glucose cotransporter), member 11 0.113
Cd40lg CD40 ligand 0.111
Thrb thyroid hormone receptor beta 0.111
Gabrb1 gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 0.111
Anxa3 annexin A3 0.107
Ikzf2 IKAROS family zinc finger 2 0.106
Tacr1 tachykinin receptor 1 0.105
Sstr4 somatostatin receptor 4 0.105
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.104
Hcrt hypocretin 0.104
Igk immunoglobulin kappa chain complex 0.103
Anxa4 annexin A4 0.101
Pou2af1 POU domain, class 2, associating factor 1 0.101
Cntn4 contactin 4 0.100
Il7 interleukin 7 0.100
Tlr4 toll-like receptor 4 0.100
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.099
Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 0.098
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 0.097
Dok7 docking protein 7 0.095
Slc17a1 solute carrier family 17 (sodium phosphate), member 1 0.091
Zeb1 zinc finger E-box binding homeobox 1 0.091
Pax4 paired box gene 4 0.090
Zfp92 zinc finger protein 92 0.090
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.089
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism