The network for 'lamellipodium organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

lamellipodium organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.

Danio rerio
Name Description Probability Func Analog Organism
dag1 dystroglycan 1 0.333
runx3 runt-related transcription factor 3 0.323
ahcyl1 S-adenosylhomocysteine hydrolase-like 1 0.167
tbx2b T-box 2b 0.154
cdc42 cell division cycle 42 0.149
dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.135
me2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.134
cnn2 calponin 2 0.112
map2k4b mitogen-activated protein kinase kinase 4b 0.109
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.105
gab1 GRB2-associated binding protein 1 0.105
dip2c DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.098
waca WW domain containing adaptor with coiled-coil a 0.095
gng3 guanine nucleotide binding protein (G protein), gamma 3 0.088
plk3 polo-like kinase 3 (Drosophila) 0.081
im:7154036 im:7154036 0.078
ptprfb protein tyrosine phosphatase, receptor type, f, b 0.077
trim71 tripartite motif-containing 71 0.076
fzd7a frizzled homolog 7a 0.075
arpc5b actin related protein 2/3 complex, subunit 5B 0.075
cbfb core-binding factor, beta subunit 0.071
igfbp3 insulin-like growth factor binding protein 3 0.068
gsna gelsolin a 0.067
ap2m1a adaptor-related protein complex 2, mu 1 subunit, a 0.066
dvl2 dishevelled, dsh homolog 2 (Drosophila) 0.064
syne1a spectrin repeat containing, nuclear envelope 1a 0.064
wdr1 WD repeat domain 1 0.063
midn midnolin 0.063
gsk3b glycogen synthase kinase 3 beta 0.063
cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.062
LOC100331639 hypothetical protein LOC100331639 0.062
zgc:66286 zgc:66286 0.060
dpysl3 dihydropyrimidinase-like 3 0.060
ergic2 ERGIC and golgi 2 0.059
tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.055
rc3 rabconnectin 3 0.053
ppm1aa protein phosphatase, Mg2+/Mn2+ dependent, 1Aa 0.053
slc4a1a solute carrier family 4, anion exchanger, member 1a 0.052
tyr tyrosinase 0.052
lhx2b LIM homeobox 2b 0.052
axin1 axin 1 0.050
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.050
robo1 roundabout homolog 1 0.050
mllt11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 0.050
ythdf1 YTH domain family, member 1 0.049
ap1g1 adaptor-related protein complex 1, gamma 1 subunit 0.048
zgc:91930 zgc:91930 0.048
insm1a insulinoma-associated 1a 0.048
tpm3 tropomyosin 3 0.048
tnnt1 troponin T1, skeletal, slow 0.048
ptprsa protein tyrosine phosphatase, receptor type, s, a 0.047
aldoaa aldolase a, fructose-bisphosphate, a 0.047
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.047
zgc:195154 zgc:195154 0.047
tmem59l transmembrane protein 59-like and transmembrane protein 59-like 0.047
ndel1a nudE nuclear distribution gene E homolog like 1 (A. nidulans) A 0.045
msxd muscle segment homeobox D 0.045
neb nebulin 0.045
flot1b flotillin 1b 0.044
macf1 microtubule-actin crosslinking factor 1 0.044
trim8 tripartite motif-containing 8 0.043
cdh2 cadherin 2, neuronal 0.043
mycbp2 MYC binding protein 2 0.043
atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.042
si:ch211-124e16.1 si:ch211-124e16.1 0.042
skia nuclear oncoprotein skia 0.042
snd1 staphylococcal nuclease domain containing 1 0.042
ptprf protein tyrosine phosphatase, receptor type, F 0.042
efnb1 ephrin B1 0.042
rbm25 RNA binding motif protein 25 0.041
dpysl2b dihydropyrimidinase-like 2b 0.041
smyd1b SET and MYND domain containing 1b 0.041
ryr3 ryanodine receptor 3 0.041
glceb glucuronyl C5-epimerase b 0.040
rhoab ras homolog gene family, member Ab 0.040
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.039
plxna4 plexin A4 0.039
mknk2b MAP kinase-interacting serine/threonine kinase 2b 0.038
lta4h leukotriene A4 hydrolase 0.038
kif7 kinesin family member 7 0.038
acsbg2 acyl-CoA synthetase bubblegum family member 2 0.038
nrarpa notch-regulated ankyrin repeat protein a 0.038
vdac3 voltage-dependent anion channel 3 0.038
taf1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.037
ddx6 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 0.037
otx5 orthodenticle homolog 5 0.037
LOC100359374 BCL-WAV 0.036
add1 adducin 1 (alpha) 0.036
vwf von Willebrand factor 0.035
cplx2l complexin 2, like 0.035
usp25 ubiquitin specific protease 25 0.035
fgfr1a fibroblast growth factor receptor 1a 0.035
tnnc2 troponin C type 2 (fast) 0.035
zgc:77409 zgc:77409 0.034
dpysl5a dihydropyrimidinase-like 5a 0.034
flncb filamin C, gamma b (actin binding protein 280) 0.034
igfbp5a insulin-like growth factor binding protein 5a 0.034
stac3 SH3 and cysteine rich domain 3 0.034
src v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.034
atp6v1al ATPase, H+ transporting, lysosomal V1 subunit A, like 0.033
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
cdc-42 Protein CDC-42 0.926
unc-60 Protein UNC-60 0.308
mig-2 Protein MIG-2 0.252
sem-5 Protein SEM-5 0.197
C52B9.4 Protein C52B9.4 0.189
goa-1 Protein GOA-1 0.179
etr-1 Protein ETR-1 0.174
sorb-1 Protein SORB-1 0.141
scpl-2 Protein SCPL-2 0.139
ina-1 Protein INA-1 0.133
unc-73 Protein UNC-73 0.119
arx-1 Protein ARX-1 0.114
sel-12 Protein SEL-12 0.112
gsp-1 Protein GSP-1 0.108
unc-50 Protein UNC-50 0.101
unc-108 Protein UNC-108 0.101
rab-1 Protein RAB-1 0.088
somi-1 Protein SOMI-1 0.087
C06G3.6 Protein C06G3.6 0.085
unc-32 Protein UNC-32 0.079
CELE_T04H1.2 Protein T04H1.2 0.073
mys-1 Protein MYS-1 0.072
unc-96 Protein UNC-96 0.071
unc-9 Protein UNC-9 0.063
emb-9 Protein EMB-9 0.062
CELE_R11H6.2 Protein R11H6.2 0.061
atgp-2 Protein ATGP-2 0.061
adm-2 Protein ADM-2 0.060
D2013.6 Protein D2013.6 0.059
pph-4.1 Protein PPH-4.1 0.059
C06G1.5 Protein C06G1.5 0.058
pkn-1 Protein PKN-1 0.057
T23F11.1 Protein T23F11.1 0.056
fce-1 Protein FCE-1 0.055
CELE_C33A12.3 Protein C33A12.3 0.053
lmn-1 Protein LMN-1 0.052
clh-5 Protein CLH-5 0.052
cdh-3 Protein CDH-3 0.052
gex-3 Protein GEX-3 0.051
praf-3 Protein PRAF-3 0.051
atg-11 Protein ATG-11 0.050
T19A6.1 Protein T19A6.1 0.048
vps-36 Protein VPS-36 0.047
CELE_B0238.10 Protein B0238.10 0.046
egl-27 Protein EGL-27 0.046
F38A5.2 Protein F38A5.2 0.046
lir-1 Protein LIR-1 0.045
F57G12.2 Protein F57G12.2 0.044
C11H1.3 Protein C11H1.3 0.044
hbl-1 Protein HBL-1 0.043
CELE_Y47G6A.18 Protein Y47G6A.18 0.043
cam-1 Protein CAM-1 0.042
abl-1 Protein ABL-1 0.042
swan-2 Protein SWAN-2 0.041
sgcb-1 Protein SGCB-1 0.041
syg-1 Protein SYG-1 0.040
alg-1 Protein ALG-1 0.040
EEED8.10 Protein EEED8.10 0.038
snf-1 Protein SNF-1 0.037
sup-12 Protein SUP-12 0.037
unc-16 Protein UNC-16 0.037
yif-1 Protein YIF-1 0.037
dpy-19 Protein DPY-19 0.037
arrd-17 Protein ARRD-17 0.037
mrps-6 Protein MRPS-6 0.036
xnp-1 Protein XNP-1 0.036
apr-1 Protein APR-1 0.036
gap-2 Protein GAP-2 0.036
F22D3.2 Protein F22D3.2 0.036
pqn-55 Protein PQN-55 0.035
unc-45 Protein UNC-45 0.035
T21B6.3 Protein T21B6.3 0.035
tag-232 Protein TAG-232 0.035
rgs-7 Protein RGS-7 0.034
pat-3 Protein PAT-3 0.034
tag-175 Protein TAG-175 0.034
ced-10 Protein CED-10 0.034
ZC506.1 Protein ZC506.1 0.034
cst-1 Protein CST-1 0.033
C18E9.2 Protein C18E9.2 0.033
tag-278 Protein TAG-278 0.033
dlg-1 Protein DLG-1 0.032
ptp-3 Protein PTP-3 0.032
gmeb-1 Protein GMEB-1 0.031
vab-8 Protein VAB-8 0.030
tag-335 Protein TAG-335 0.030
F21A10.2 Protein F21A10.2 0.030
cpna-5 Protein CPNA-5 0.029
sax-3 Protein SAX-3 0.029
CELE_Y57G11C.3 Protein Y57G11C.3 0.028
igcm-3 Protein IGCM-3 0.028
cnt-2 Protein CNT-2 0.028
C41H7.5 Protein C41H7.5 0.028
C34F6.10 Protein C34F6.10 0.027
zfp-3 Protein ZFP-3 0.027
acs-17 Protein ACS-17 0.027
CELE_Y48A6C.4 Protein Y48A6C.4 0.027
C11E4.6 Protein C11E4.6 0.026
xbx-6 Protein XBX-6 0.026
cdka-1 Protein CDKA-1 0.026
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
robo roundabout 0.938
da daughterless 0.819
Sra-1 specifically Rac1-associated protein 1 0.760
Rho1 CG8416 gene product from transcript CG8416-RB 0.682
Hem HEM-protein 0.665
cpb capping protein beta 0.555
Vrp1 Verprolin 1 0.544
ena enabled 0.465
lea leak 0.325
rok Rho-kinase 0.307
kuz kuzbanian 0.283
Abi Abelson interacting protein 0.215
Abl Abl tyrosine kinase 0.203
trio CG18214 gene product from transcript CG18214-RA 0.190
sli slit 0.174
Arp14D Actin-related protein 14D 0.173
Ephrin CG1862 gene product from transcript CG1862-RA 0.172
chic chickadee 0.158
Cdc42 CG12530 gene product from transcript CG12530-RA 0.149
Wnt5 Wnt oncogene analog 5 0.148
Rala Ras-related protein 0.125
Dscam Down syndrome cell adhesion molecule 0.110
Rac1 CG2248 gene product from transcript CG2248-RA 0.106
msn misshapen 0.104
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.094
cta concertina 0.092
LamC Lamin C 0.087
Sop2 Suppressor of profilin 2 0.076
S6k RPS6-p70-protein kinase 0.074
pll pelle 0.073
RhoGAPp190 CG32555 gene product from transcript CG32555-RB 0.073
l(2)k16918 lethal (2) k16918 0.072
bif bifocal 0.071
RhoGAP93B CG3421 gene product from transcript CG3421-RA 0.071
RanBPM Ran-binding protein M 0.069
mid midline 0.067
egh egghead 0.066
otk off-track 0.066
comm commissureless 0.065
Dlic Dynein light intermediate chain 0.064
Mrtf Myocardin-related transcription factor 0.064
Myo31DF Myosin 31DF 0.061
twi twist 0.057
Rac2 CG8556 gene product from transcript CG8556-RA 0.057
cora coracle 0.056
dock dreadlocks 0.056
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.055
HSPC300 CG30173 gene product from transcript CG30173-RA 0.054
fra frazzled 0.054
pod1 CG4532 gene product from transcript CG4532-RF 0.053
zfh1 Zn finger homeodomain 1 0.050
hkb huckebein 0.045
LIMK1 LIM-kinase1 0.045
fz frizzled 0.044
par-1 CG8201 gene product from transcript CG8201-RA 0.044
Arp66B Actin-related protein 66B 0.040
flr flare 0.038
CG17082 CG17082 gene product from transcript CG17082-RD 0.038
Stim Stromal interaction molecule 0.036
WASp CG1520 gene product from transcript CG1520-RA 0.034
mbc myoblast city 0.034
slp1 sloppy paired 1 0.033
faf fat facets 0.032
Gef26 CG9491 gene product from transcript CG9491-RB 0.031
Khc Kinesin heavy chain 0.031
exba extra bases 0.030
Dap160 Dynamin associated protein 160 0.029
kni knirps 0.029
caz cabeza 0.029
ems empty spiracles 0.029
bin biniou 0.029
Rab23 CG2108 gene product from transcript CG2108-RA 0.028
Rab2 Rab-protein 2 0.027
not non-stop 0.027
in inturned 0.026
Rab6 Rab-protein 6 0.026
Lim3 CG10699 gene product from transcript CG10699-RB 0.026
schlank CG3576 gene product from transcript CG3576-RB 0.025
stan starry night 0.025
NetB Netrin-B 0.025
gcm glial cells missing 0.023
katanin-60 katanin 60 0.023
drl derailed 0.022
tll tailless 0.022
Uba1 Ubiquitin activating enzyme 1 0.022
CG12289 CG12289 gene product from transcript CG12289-RA 0.021
Arf51F ADP ribosylation factor 51F 0.021
Caps Calcium activated protein for secretion 0.020
FucT6 alpha1,6-fucosyltransferase 0.020
Pvf1 PDGF- and VEGF-related factor 1 0.020
byn brachyenteron 0.020
CkIIbeta Casein kinase II beta subunit 0.020
sn singed 0.020
Tre1 trapped in endoderm-1 0.019
Rpn6 Proteasome p44.5 subunit 0.019
yki yorkie 0.019
hipk homeodomain interacting protein kinase 0.019
beta-Spec beta Spectrin 0.018
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.018
CG11791 CG11791 gene product from transcript CG11791-RB 0.018
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.999
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.988
ILK integrin-linked kinase 0.842
GRB7 growth factor receptor-bound protein 7 0.829
ZNF746 zinc finger protein 746 0.807
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.726
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.706
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.678
GRB2 growth factor receptor-bound protein 2 0.656
VAV1 vav 1 guanine nucleotide exchange factor 0.652
BAIAP2 BAI1-associated protein 2 0.610
GAS7 growth arrest-specific 7 0.596
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.586
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.462
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.392
PRKCZ protein kinase C, zeta 0.387
NCK1 NCK adaptor protein 1 0.365
TWF2 twinfilin, actin-binding protein, homolog 2 (Drosophila) 0.343
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.334
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.326
EPS8 epidermal growth factor receptor pathway substrate 8 0.318
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.308
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.282
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.259
LIMS1 LIM and senescent cell antigen-like domains 1 0.231
SORBS3 sorbin and SH3 domain containing 3 0.224
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.222
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.218
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.212
CSNK1E casein kinase 1, epsilon 0.187
PLCG1 phospholipase C, gamma 1 0.184
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.178
TRIP6 thyroid hormone receptor interactor 6 0.176
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.175
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.164
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.155
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.152
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.152
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.150
DSG2 desmoglein 2 0.148
NCOA1 nuclear receptor coactivator 1 0.140
VHL von Hippel-Lindau tumor suppressor 0.138
JUP junction plakoglobin 0.128
INSR insulin receptor 0.125
CTNND1 catenin (cadherin-associated protein), delta 1 0.122
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.119
EFNA5 ephrin-A5 0.115
CD2AP CD2-associated protein 0.113
ATN1 atrophin 1 0.108
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.106
LDOC1 leucine zipper, down-regulated in cancer 1 0.104
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.100
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.095
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.093
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.092
WASF1 WAS protein family, member 1 0.091
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.091
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.090
ABI1 abl-interactor 1 0.088
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.086
ADAM19 ADAM metallopeptidase domain 19 0.085
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.083
MAPK8 mitogen-activated protein kinase 8 0.079
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.076
SPTBN1 spectrin, beta, non-erythrocytic 1 0.074
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.072
FYN FYN oncogene related to SRC, FGR, YES 0.071
KIF5B kinesin family member 5B 0.071
EFNA1 ephrin-A1 0.070
SNAI1 snail homolog 1 (Drosophila) 0.069
EGFR epidermal growth factor receptor 0.068
PFDN1 prefoldin subunit 1 0.067
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.066
FN1 fibronectin 1 0.063
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.061
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.061
NCKAP1 NCK-associated protein 1 0.060
CAPZB capping protein (actin filament) muscle Z-line, beta 0.057
FMNL1 formin-like 1 0.057
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.056
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.056
LRRK2 leucine-rich repeat kinase 2 0.055
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.055
ABI2 abl-interactor 2 0.055
COTL1 coactosin-like 1 (Dictyostelium) 0.054
CHRD chordin 0.052
MEF2C myocyte enhancer factor 2C 0.051
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 0.050
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.049
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.046
PXN paxillin 0.046
SH3KBP1 SH3-domain kinase binding protein 1 0.046
ZYX zyxin 0.044
NCKIPSD NCK interacting protein with SH3 domain 0.044
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.043
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.043
LRP6 low density lipoprotein receptor-related protein 6 0.042
TLN1 talin 1 0.041
MSN moesin 0.041
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.041
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.994
Vasp vasodilator-stimulated phosphoprotein 0.974
Vangl2 vang-like 2 (van gogh, Drosophila) 0.954
Enah enabled homolog (Drosophila) 0.953
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.933
Pxn paxillin 0.906
Ctnnb1 catenin (cadherin associated protein), beta 1 0.878
Tgfb1 transforming growth factor, beta 1 0.830
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.828
Wdr1 WD repeat domain 1 0.827
Vangl1 vang-like 1 (van gogh, Drosophila) 0.807
Ilk integrin linked kinase 0.753
Ncf1 neutrophil cytosolic factor 1 0.741
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.700
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.670
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.637
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.633
Cttn cortactin 0.572
Pecam1 platelet/endothelial cell adhesion molecule 1 0.561
Lrrk2 leucine-rich repeat kinase 2 0.536
Vav2 vav 2 oncogene 0.518
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.499
Tek endothelial-specific receptor tyrosine kinase 0.488
Vav1 vav 1 oncogene 0.486
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.437
Src Rous sarcoma oncogene 0.437
Vcl vinculin 0.434
Wasf2 WAS protein family, member 2 0.399
Plcg1 phospholipase C, gamma 1 0.393
Cdh5 cadherin 5 0.376
Grxcr1 glutaredoxin, cysteine rich 1 0.375
Msn moesin 0.364
Smurf2 SMAD specific E3 ubiquitin protein ligase 2 0.340
Efnb1 ephrin B1 0.328
Myo6 myosin VI 0.318
Ush1g Usher syndrome 1G homolog (human) 0.317
Dok1 docking protein 1 0.316
Ptk7 PTK7 protein tyrosine kinase 7 0.315
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.308
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.304
Cltc clathrin, heavy polypeptide (Hc) 0.282
Mef2d myocyte enhancer factor 2D 0.265
S1pr2 sphingosine-1-phosphate receptor 2 0.250
Wwtr1 WW domain containing transcription regulator 1 0.246
Abi1 abl-interactor 1 0.244
Fmnl1 formin-like 1 0.242
Ush1c Usher syndrome 1C homolog (human) 0.234
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.233
Csf1 colony stimulating factor 1 (macrophage) 0.231
Kitl kit ligand 0.229
She src homology 2 domain-containing transforming protein E 0.229
Arpc4 actin related protein 2/3 complex, subunit 4 0.227
Tln1 talin 1 0.225
Parva parvin, alpha 0.223
Slit3 slit homolog 3 (Drosophila) 0.212
Efnb2 ephrin B2 0.207
Myl9 myosin, light polypeptide 9, regulatory 0.204
Marcks myristoylated alanine rich protein kinase C substrate 0.195
Cdc42se1 CDC42 small effector 1 0.191
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.177
Apaf1 apoptotic peptidase activating factor 1 0.176
Cd37 CD37 antigen 0.169
Mtpn myotrophin 0.169
Tax1bp3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.159
Pfn2 profilin 2 0.159
Ednrb endothelin receptor type B 0.155
Wipf1 WAS/WASL interacting protein family, member 1 0.155
Nckap1l NCK associated protein 1 like 0.154
S1pr3 sphingosine-1-phosphate receptor 3 0.153
Flt1 FMS-like tyrosine kinase 1 0.149
Sirpa signal-regulatory protein alpha 0.144
Pdlim7 PDZ and LIM domain 7 0.142
Cnn2 calponin 2 0.142
Evl Ena-vasodilator stimulated phosphoprotein 0.140
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.139
Capn2 calpain 2 0.139
Smad3 MAD homolog 3 (Drosophila) 0.137
Myo1c myosin IC 0.132
Capzb capping protein (actin filament) muscle Z-line, beta 0.131
Vav3 vav 3 oncogene 0.130
Rhoa ras homolog gene family, member A 0.128
6720456B07Rik RIKEN cDNA 6720456B07 gene 0.121
Ctnna1 catenin (cadherin associated protein), alpha 1 0.119
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.118
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.115
Cd97 CD97 antigen 0.114
Capza1 capping protein (actin filament) muscle Z-line, alpha 1 0.114
Lasp1 LIM and SH3 protein 1 0.111
Csrp1 cysteine and glycine-rich protein 1 0.108
Smad6 MAD homolog 6 (Drosophila) 0.108
Gpr132 G protein-coupled receptor 132 0.107
Git1 G protein-coupled receptor kinase-interactor 1 0.106
Ttc7 tetratricopeptide repeat domain 7 0.106
Zyx zyxin 0.105
Tns1 tensin 1 0.105
Sept7 septin 7 0.104
Rgs14 regulator of G-protein signaling 14 0.100
Tagln transgelin 0.092
9430031J16Rik RIKEN cDNA 9430031J16 gene 0.092
Mapkap1 mitogen-activated protein kinase associated protein 1 0.091
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Rattus norvegicus
Name Description Probability Func Analog Organism
Actb actin, beta 0.142
Actg1 actin, gamma 1 0.064
Arpc2 actin related protein 2/3 complex, subunit 2 0.044
Hspa8 heat shock protein 8 0.039
Tpm3 tropomyosin 3, gamma 0.028
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.019
Hspd1 heat shock protein 1 (chaperonin) 0.018
Hsph1 heat shock 105/110 protein 1 0.017
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.015
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.013
Wdr1 WD repeat domain 1 0.012
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.011
Msn moesin 0.011
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism