Mus musculus

227 known processes

Zeb1

zinc finger E-box binding homeobox 1

(Aliases: ZEB,BZP,Zfhep,Zfx1a,Tcf8,3110032K11Rik,AREB6,Zfx1ha,Nil2,[delta]EF1,MEB1,Zfhx1a,Tcf18)

Zeb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ morphogenesis GO:0090596 242 1.000
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 1.000
morphogenesis of a branching epithelium GO:0061138 193 0.999
regionalization GO:0003002 337 0.999
Mouse
embryonic skeletal system development GO:0048706 120 0.999
cell proliferation in hindbrain GO:0021534 10 0.999
auditory receptor cell fate determination GO:0042668 3 0.998
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.998
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.997
skeletal system development GO:0001501 356 0.994
epithelial tube morphogenesis GO:0060562 303 0.993
Mouse
embryonic organ morphogenesis GO:0048562 276 0.993
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.992
digestive system development GO:0055123 200 0.992
Zebrafish
appendage morphogenesis GO:0035107 149 0.991
ear development GO:0043583 200 0.991
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.988
endodermal cell fate specification GO:0001714 4 0.988
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.987
axon guidance GO:0007411 141 0.987
Fly
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.983
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.982
neuron projection guidance GO:0097485 141 0.980
Fly
telencephalon development GO:0021537 186 0.979
Mouse
pyramidal neuron migration GO:0021852 1 0.979
mammary gland epithelium development GO:0061180 65 0.979
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.979
regulation of cell activation GO:0050865 289 0.978
mesonephric tubule development GO:0072164 94 0.978
cerebellar granule cell precursor proliferation GO:0021930 10 0.978
face morphogenesis GO:0060325 29 0.977
metanephric nephron tubule formation GO:0072289 4 0.976
branching morphogenesis of an epithelial tube GO:0048754 159 0.975
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.975
cell fate commitment GO:0045165 210 0.974
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.973
artery development GO:0060840 53 0.972
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.971
regulation of mesenchymal cell proliferation GO:0010464 37 0.970
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.967
neural tube patterning GO:0021532 43 0.967
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.964
metanephric capsule specification GO:0072267 1 0.964
gastrulation GO:0007369 116 0.963
Zebrafish
negative regulation of cell proliferation GO:0008285 296 0.962
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.960
negative regulation of stem cell maintenance GO:1902455 4 0.960
lymphocyte differentiation GO:0030098 242 0.959
positive regulation of transcription by glucose GO:0046016 3 0.958
stem cell development GO:0048864 219 0.957
Mouse
pallium development GO:0021543 120 0.957
Mouse
single organismal cell cell adhesion GO:0016337 131 0.954
Zebrafish
negative regulation of protein modification process GO:0031400 163 0.953
palate development GO:0060021 76 0.952
digestive tract morphogenesis GO:0048546 147 0.951
Zebrafish
axial mesodermal cell fate commitment GO:0048322 1 0.950
formation of radial glial scaffolds GO:0021943 4 0.950
striated muscle tissue development GO:0014706 293 0.949
tissue migration GO:0090130 68 0.947
Mouse
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.947
mammary placode formation GO:0060596 4 0.946
cartilage condensation GO:0001502 18 0.945
regulation of vascular wound healing GO:0061043 2 0.945
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.942
leukocyte proliferation GO:0070661 172 0.939
mesoderm development GO:0007498 100 0.936
Fly
leukocyte differentiation GO:0002521 342 0.933
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.932
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.931
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.930
lymphocyte proliferation GO:0046651 164 0.930
osteoblast development GO:0002076 17 0.929
negative regulation of leukocyte differentiation GO:1902106 51 0.926
negative regulation of cell activation GO:0050866 111 0.926
mammary gland duct morphogenesis GO:0060603 38 0.922
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.922
negative regulation of cellular amine metabolic process GO:0033239 1 0.921
camera type eye development GO:0043010 266 0.921
actin cytoskeleton organization GO:0030036 220 0.921
stem cell maintenance GO:0019827 130 0.920
axonogenesis GO:0007409 274 0.919
Fly
hindbrain development GO:0030902 128 0.916
positive regulation of hh target transcription factor activity GO:0007228 3 0.913
multicellular organism growth GO:0035264 161 0.911
alpha beta t cell differentiation GO:0046632 69 0.910
negative regulation of neuron differentiation GO:0045665 101 0.910
retinal ganglion cell axon guidance GO:0031290 18 0.906
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.906
stem cell differentiation GO:0048863 268 0.905
Mouse
regulation of neuron projection development GO:0010975 169 0.903
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.901
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.901
locus ceruleus development GO:0021703 1 0.899
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.899
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.898
negative regulation of phosphorylation GO:0042326 166 0.894
regulation of wnt signaling pathway GO:0030111 123 0.893
Mouse
t cell differentiation GO:0030217 174 0.892
cerebral cortex neuron differentiation GO:0021895 19 0.891
embryonic heart tube formation GO:0003144 1 0.891
positive regulation of stem cell proliferation GO:2000648 59 0.889
male gamete generation GO:0048232 285 0.888
cellular ketone metabolic process GO:0042180 84 0.883
embryonic skeletal system morphogenesis GO:0048704 91 0.883
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.882
tendon formation GO:0035992 4 0.881
closure of optic fissure GO:0061386 2 0.878
chromatin organization GO:0006325 206 0.877
ear morphogenesis GO:0042471 118 0.877
adaptive immune response GO:0002250 155 0.877
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.875
anterior commissure morphogenesis GO:0021960 6 0.875
cell proliferation in external granule layer GO:0021924 10 0.873
developmental programmed cell death GO:0010623 41 0.872
bmp signaling pathway GO:0030509 93 0.872
dna metabolic process GO:0006259 303 0.872
semicircular canal development GO:0060872 9 0.869
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.868
cell fate specification GO:0001708 72 0.866
ureter morphogenesis GO:0072197 4 0.865
regulation of secretion by cell GO:1903530 249 0.865
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.865
striated muscle cell development GO:0055002 125 0.865
negative regulation of glial cell proliferation GO:0060253 4 0.862
embryonic camera type eye development GO:0031076 36 0.862
retina development in camera type eye GO:0060041 119 0.861
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.861
central nervous system neuron differentiation GO:0021953 162 0.861
segmentation GO:0035282 93 0.860
Mouse
t cell activation GO:0042110 289 0.860
neural tube development GO:0021915 160 0.858
Mouse
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis GO:0072309 3 0.858
regulation of cellular amino acid metabolic process GO:0006521 5 0.856
forebrain radial glial cell differentiation GO:0021861 4 0.854
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.853
mapk cascade GO:0000165 281 0.852
Mouse
mammary gland morphogenesis GO:0060443 54 0.852
inner cell mass cellular morphogenesis GO:0001828 1 0.852
internal protein amino acid acetylation GO:0006475 42 0.850
regulation of cellular ketone metabolic process GO:0010565 66 0.846
trophectodermal cellular morphogenesis GO:0001831 3 0.843
negative regulation of molecular function GO:0044092 258 0.843
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.843
diencephalon development GO:0021536 63 0.842
spinal cord motor neuron differentiation GO:0021522 35 0.841
aorta morphogenesis GO:0035909 22 0.839
immune effector process GO:0002252 321 0.839
alpha beta t cell activation GO:0046631 91 0.836
regulation of intracellular transport GO:0032386 159 0.836
gland development GO:0048732 330 0.836
Fly
negative regulation of cell development GO:0010721 169 0.835
head morphogenesis GO:0060323 34 0.834
salivary gland morphogenesis GO:0007435 33 0.831
pigmentation GO:0043473 71 0.828
Mouse
leukocyte mediated immunity GO:0002443 174 0.825
t cell differentiation involved in immune response GO:0002292 30 0.824
blood vessel morphogenesis GO:0048514 285 0.822
negative regulation of lymphocyte activation GO:0051250 91 0.822
embryonic genitalia morphogenesis GO:0030538 4 0.821
b cell activation GO:0042113 161 0.820
embryonic viscerocranium morphogenesis GO:0048703 8 0.819
regulation of secretion GO:0051046 274 0.817
carbon catabolite repression of transcription GO:0045013 1 0.817
regulation of auditory receptor cell differentiation GO:0045607 4 0.813
inner ear receptor cell differentiation GO:0060113 61 0.813
endodermal cell fate commitment GO:0001711 12 0.812
skeletal muscle organ development GO:0060538 163 0.810
cardiac ventricle morphogenesis GO:0003208 50 0.807
digestive tract development GO:0048565 190 0.807
Zebrafish
negative regulation of protein metabolic process GO:0051248 282 0.801
ascending aorta morphogenesis GO:0035910 3 0.796
regulation of cardiac muscle tissue development GO:0055024 31 0.794
primary prostatic bud elongation GO:0060516 2 0.791
peptidyl lysine modification GO:0018205 77 0.787
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.785
negative regulation of phosphorus metabolic process GO:0010563 184 0.785
forebrain development GO:0030900 302 0.782
Mouse Rat
odontogenesis of dentin containing tooth GO:0042475 66 0.780
negative regulation of lymphocyte differentiation GO:0045620 32 0.780
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.779
cell type specific apoptotic process GO:0097285 268 0.777
regulation of neuron differentiation GO:0045664 281 0.777
rhombomere morphogenesis GO:0021593 2 0.775
somite specification GO:0001757 4 0.775
regulation of leukocyte differentiation GO:1902105 159 0.774
camera type eye photoreceptor cell differentiation GO:0060219 15 0.774
mesenchymal cell proliferation GO:0010463 44 0.773
anatomical structure homeostasis GO:0060249 145 0.772
morphogenesis of a branching structure GO:0001763 203 0.768
midbrain hindbrain boundary development GO:0030917 9 0.768
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.765
regulation of lymphocyte proliferation GO:0050670 117 0.763
otolith morphogenesis GO:0032474 3 0.762
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.762
positive regulation of cell death GO:0010942 224 0.761
cerebellum morphogenesis GO:0021587 42 0.757
signal transduction in absence of ligand GO:0038034 55 0.755
embryonic heart tube morphogenesis GO:0003143 51 0.753
eye photoreceptor cell differentiation GO:0001754 41 0.752
regulation of leukocyte proliferation GO:0070663 121 0.751
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.750
chemotaxis GO:0006935 247 0.750
Fly
regulation of metal ion transport GO:0010959 106 0.748
spermatid differentiation GO:0048515 115 0.747
regulation of heart morphogenesis GO:2000826 22 0.745
cerebral cortex radially oriented cell migration GO:0021799 31 0.743
regulation of t cell proliferation GO:0042129 92 0.741
regulation of organ morphogenesis GO:2000027 144 0.739
respiratory system development GO:0060541 190 0.738
epithelial cell proliferation GO:0050673 174 0.733
negative regulation of cellular component organization GO:0051129 194 0.733
establishment or maintenance of neuroblast polarity GO:0045196 1 0.732
regulation of fat cell differentiation GO:0045598 81 0.729
establishment of neuroblast polarity GO:0045200 1 0.723
cellular amine metabolic process GO:0044106 44 0.723
lung development GO:0030324 164 0.723
roof plate formation GO:0021509 1 0.722
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.721
cardiac chamber morphogenesis GO:0003206 93 0.721
regulation of leukocyte mediated immunity GO:0002703 104 0.719
regulation of somitogenesis GO:0014807 6 0.718
branching involved in ureteric bud morphogenesis GO:0001658 56 0.717
somitogenesis GO:0001756 69 0.715
Mouse
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.712
cellular chemical homeostasis GO:0055082 215 0.712
metanephric nephron tubule epithelial cell differentiation GO:0072257 5 0.710
covalent chromatin modification GO:0016569 163 0.710
chondrocyte differentiation GO:0002062 72 0.709
neural tube closure GO:0001843 90 0.709
Mouse
astrocyte fate commitment GO:0060018 4 0.709
regulation of b cell activation GO:0050864 81 0.705
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.701
positive regulation of apoptotic process GO:0043065 217 0.700
limb morphogenesis GO:0035108 149 0.699
respiratory tube development GO:0030323 167 0.698
hindbrain tangential cell migration GO:0021934 2 0.697
olfactory lobe development GO:0021988 32 0.696
tube formation GO:0035148 140 0.696
Mouse
production of molecular mediator of immune response GO:0002440 103 0.694
metal ion homeostasis GO:0055065 189 0.692
regulation of cell adhesion GO:0030155 154 0.689
Zebrafish
regulation of skeletal muscle fiber development GO:0048742 36 0.687
lateral mesoderm formation GO:0048370 3 0.686
jak stat cascade GO:0007259 42 0.685
fat cell differentiation GO:0045444 160 0.684
hexose metabolic process GO:0019318 98 0.683
somite development GO:0061053 81 0.682
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.681
regulation of mesodermal cell fate specification GO:0042661 5 0.678
stem cell proliferation GO:0072089 117 0.677
regulation of lymphocyte activation GO:0051249 240 0.676
cell differentiation in hindbrain GO:0021533 24 0.675
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.673
face development GO:0060324 38 0.668
regulation of protein localization GO:0032880 231 0.667
forelimb morphogenesis GO:0035136 40 0.666
epithelial to mesenchymal transition GO:0001837 47 0.665
regulation of organelle organization GO:0033043 289 0.664
Mouse
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.662
regulation of chromosome organization GO:0033044 83 0.661
regulation of cardiac chamber morphogenesis GO:1901219 2 0.661
mesonephros development GO:0001823 97 0.660
formation of primary germ layer GO:0001704 77 0.656
regulation of retina development in camera type eye GO:1902866 3 0.655
b cell differentiation GO:0030183 78 0.650
ventricular zone neuroblast division GO:0021847 3 0.649
ventricular septum morphogenesis GO:0060412 27 0.649
asymmetric neuroblast division GO:0055059 1 0.647
optic nerve formation GO:0021634 1 0.647
positive regulation of secretion GO:0051047 130 0.646
positive regulation of neuron projection regeneration GO:0070572 2 0.646
forebrain morphogenesis GO:0048853 17 0.646
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.645
axis elongation involved in somitogenesis GO:0090245 4 0.643
negative regulation of histone modification GO:0031057 18 0.643
ureteric bud development GO:0001657 94 0.642
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.642
muscle cell differentiation GO:0042692 261 0.641
regulation of cell cycle process GO:0010564 160 0.640
female sex determination GO:0030237 1 0.640
positive regulation of programmed cell death GO:0043068 218 0.639
forebrain generation of neurons GO:0021872 63 0.636
inner ear morphogenesis GO:0042472 101 0.633
histone acetylation GO:0016573 41 0.631
telencephalon cell migration GO:0022029 55 0.629
chromatin modification GO:0016568 187 0.627
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.627
regulation of kinase activity GO:0043549 249 0.626
Mouse
odontogenesis GO:0042476 78 0.623
neuron maturation GO:0042551 29 0.622
vascular wound healing GO:0061042 3 0.621
cation transport GO:0006812 399 0.620
skeletal muscle cell differentiation GO:0035914 66 0.620
cellular amino acid metabolic process GO:0006520 103 0.619
developmental growth involved in morphogenesis GO:0060560 138 0.616
myelination in peripheral nervous system GO:0022011 19 0.616
clara cell differentiation GO:0060486 4 0.616
renal vesicle induction GO:0072034 3 0.614
endodermal cell fate determination GO:0007493 2 0.612
regulation of bmp signaling pathway GO:0030510 60 0.612
cardiac endothelial cell differentiation GO:0003348 4 0.610
semicircular canal formation GO:0060876 1 0.608
negative regulation of anoikis GO:2000811 2 0.608
metanephric dct cell differentiation GO:0072240 3 0.607
renal system development GO:0072001 225 0.606
Fly
spinal cord development GO:0021510 81 0.606
sinoatrial node cell differentiation GO:0060921 3 0.606
lateral mesodermal cell differentiation GO:0048371 3 0.605
cochlea morphogenesis GO:0090103 22 0.604
floor plate morphogenesis GO:0033505 3 0.602
medulla oblongata development GO:0021550 3 0.600
cardiac muscle cell development GO:0055013 39 0.598
axon target recognition GO:0007412 4 0.598
lateral mesoderm morphogenesis GO:0048369 3 0.597
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.596
mesonephric epithelium development GO:0072163 94 0.595
cerebral cortex cell migration GO:0021795 44 0.594
regulation of heart growth GO:0060420 31 0.592
leukocyte activation involved in immune response GO:0002366 126 0.592
somatic stem cell maintenance GO:0035019 47 0.588
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.586
amine metabolic process GO:0009308 45 0.585
cerebellum development GO:0021549 77 0.585
pituitary gland development GO:0021983 38 0.585
negative regulation of protein processing GO:0010955 79 0.584
mitral valve morphogenesis GO:0003183 4 0.584
chondrocyte development GO:0002063 24 0.583
positive regulation of ossification GO:0045778 47 0.581
peptide transport GO:0015833 133 0.581
embryonic skeletal joint morphogenesis GO:0060272 11 0.581
regulation of t cell activation GO:0050863 170 0.581
mesenchymal cell development GO:0014031 93 0.579
Mouse
mesoderm morphogenesis GO:0048332 64 0.578
embryonic eye morphogenesis GO:0048048 29 0.578
positive regulation of cell activation GO:0050867 158 0.576
otic placode formation GO:0043049 1 0.575
regulation of cell cycle GO:0051726 281 0.573
regulation of t cell differentiation GO:0045580 83 0.572
positive regulation of heart growth GO:0060421 18 0.570
regulation of transferase activity GO:0051338 263 0.569
Mouse
regulation of astrocyte differentiation GO:0048710 20 0.568
negative regulation of immune system process GO:0002683 209 0.568
embryonic neurocranium morphogenesis GO:0048702 3 0.567
carbohydrate homeostasis GO:0033500 128 0.567
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.566
hair cell differentiation GO:0035315 40 0.564
positive regulation of cell development GO:0010720 237 0.561
cardiac atrium morphogenesis GO:0003209 23 0.559
microtubule cytoskeleton organization GO:0000226 157 0.556
cellular response to lipid GO:0071396 145 0.554
cardiac muscle tissue morphogenesis GO:0055008 44 0.551
dorsal aorta morphogenesis GO:0035912 5 0.548
cell activation involved in immune response GO:0002263 126 0.547
urogenital system development GO:0001655 261 0.544
Fly
cellular homeostasis GO:0019725 240 0.544
noradrenergic neuron differentiation GO:0003357 6 0.544
dorsal ventral neural tube patterning GO:0021904 28 0.543
histone methylation GO:0016571 71 0.541
branch elongation involved in ureteric bud branching GO:0060681 3 0.539
ossification GO:0001503 216 0.535
prostate gland morphogenetic growth GO:0060737 4 0.535
oligodendrocyte development GO:0014003 20 0.534
negative regulation of kinase activity GO:0033673 81 0.534
immune response activating signal transduction GO:0002757 116 0.534
dendrite extension GO:0097484 3 0.533
cell migration in hindbrain GO:0021535 16 0.533
spermatogenesis GO:0007283 284 0.529
extracellular structure organization GO:0043062 148 0.529
aorta development GO:0035904 23 0.529
carbon catabolite activation of transcription GO:0045991 4 0.528
negative regulation of chromosome organization GO:2001251 30 0.528
regulation of cytokine production GO:0001817 266 0.523
detection of external stimulus GO:0009581 61 0.523
metanephric capsule formation GO:0072266 1 0.522
regulation of cellular amine metabolic process GO:0033238 20 0.521
negative regulation of lymphocyte proliferation GO:0050672 45 0.521
morphogenesis of embryonic epithelium GO:0016331 159 0.520
Mouse
kidney morphogenesis GO:0060993 83 0.519
semicircular canal morphogenesis GO:0048752 7 0.518
regulation of response to wounding GO:1903034 189 0.518
mesenchyme development GO:0060485 152 0.518
Mouse
canonical wnt signaling pathway GO:0060070 130 0.517
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.514
regulation of binding GO:0051098 111 0.514
negative regulation of t cell activation GO:0050868 65 0.514
positive regulation of protein modification process GO:0031401 299 0.511
Mouse
cell migration involved in gastrulation GO:0042074 13 0.511
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.510
negative regulation of immune effector process GO:0002698 55 0.509
middle ear morphogenesis GO:0042474 23 0.507
mammary gland specification GO:0060594 4 0.506
nephron development GO:0072006 109 0.502
response to amino acid GO:0043200 37 0.500
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.499
regulation of cardiac chamber formation GO:1901210 1 0.499
apoptotic process involved in morphogenesis GO:0060561 25 0.497
embryonic limb morphogenesis GO:0030326 126 0.497
negative regulation of astrocyte differentiation GO:0048712 10 0.497
negative regulation of t cell differentiation GO:0045581 23 0.496
cardiac left ventricle formation GO:0003218 1 0.496
regulation of chromatin modification GO:1903308 57 0.494
tendon cell differentiation GO:0035990 4 0.490
regulation of hormone levels GO:0010817 211 0.487
negative regulation of protein phosphorylation GO:0001933 126 0.487
limb development GO:0060173 166 0.486
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.485
somatic diversification of immune receptors GO:0002200 53 0.483
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.482
cerebral cortex development GO:0021987 86 0.481
endocardial cushion formation GO:0003272 13 0.478
cranial nerve formation GO:0021603 4 0.477
positive regulation of wnt signaling pathway GO:0030177 45 0.473
Mouse
trophectodermal cell differentiation GO:0001829 21 0.472
bmp signaling pathway involved in mesodermal cell fate specification GO:0060803 1 0.471
bmp signaling pathway involved in heart development GO:0061312 2 0.470
macromolecule deacylation GO:0098732 37 0.470
cellular response to growth factor stimulus GO:0071363 197 0.469
cardiac chamber development GO:0003205 108 0.469
axial mesoderm formation GO:0048320 3 0.468
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.468
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.467
carbohydrate metabolic process GO:0005975 230 0.467
neuron apoptotic process GO:0051402 142 0.466
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.465
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.465
regulation of cell adhesion mediated by integrin GO:0033628 13 0.465
detection of stimulus GO:0051606 84 0.462
retinal rod cell differentiation GO:0060221 2 0.460
eye photoreceptor cell development GO:0042462 31 0.460
negative regulation of proteolysis GO:0045861 74 0.458
glomerular mesangial cell differentiation GO:0072008 3 0.457
foregut morphogenesis GO:0007440 12 0.456
hemangioblast cell differentiation GO:0060217 1 0.455
cytokine production involved in immune response GO:0002367 34 0.455
smooth muscle tissue development GO:0048745 22 0.454
regulation of jak stat cascade GO:0046425 34 0.454
negative regulation of heart looping GO:1901208 1 0.453
neuroblast division GO:0055057 10 0.450
muscle tissue morphogenesis GO:0060415 53 0.449
muscle cell proliferation GO:0033002 52 0.449
wnt signaling pathway GO:0016055 188 0.448
Mouse
regulation of histone modification GO:0031056 56 0.447
regulation of striated muscle cell differentiation GO:0051153 81 0.446
regulation of neuron maturation GO:0014041 5 0.446
g protein coupled receptor signaling pathway GO:0007186 243 0.445
atrial septum primum morphogenesis GO:0003289 3 0.444
mesodermal cell fate specification GO:0007501 11 0.441
metanephros development GO:0001656 79 0.440
negative regulation of leukocyte proliferation GO:0070664 46 0.440
epidermis development GO:0008544 187 0.440
negative regulation of organelle organization GO:0010639 90 0.439
cell maturation GO:0048469 127 0.438
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.435
regulation of canonical wnt signaling pathway GO:0060828 82 0.435
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.435
protein methylation GO:0006479 81 0.434
regulation of mast cell differentiation GO:0060375 3 0.433
pancreatic pp cell fate commitment GO:0003329 2 0.430
regulation of glial cell differentiation GO:0045685 41 0.429
regulation of alpha beta t cell differentiation GO:0046637 35 0.428
regulation of hormone secretion GO:0046883 88 0.427
mitotic cell cycle process GO:1903047 159 0.426
positive regulation of nervous system development GO:0051962 221 0.425
regulation of cardiac muscle cell proliferation GO:0060043 23 0.424
negative regulation of alpha beta t cell differentiation GO:0046639 12 0.423
negative regulation of chromatin modification GO:1903309 19 0.422
positive regulation of hormone secretion GO:0046887 38 0.422
endocardium development GO:0003157 10 0.421
embryonic placenta development GO:0001892 98 0.420
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.417
regulation of lipid transport GO:0032368 36 0.412
negative regulation of neuron projection development GO:0010977 50 0.412
organelle localization GO:0051640 179 0.410
humoral immune response GO:0006959 57 0.409
Fly
regulation of alpha beta t cell activation GO:0046634 53 0.409
cellular response to acid chemical GO:0071229 68 0.408
neural crest formation GO:0014029 2 0.408
forebrain cell migration GO:0021885 58 0.407
mesoderm formation GO:0001707 62 0.405
cranial suture morphogenesis GO:0060363 8 0.405
regulation of epithelial cell proliferation GO:0050678 141 0.404
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.402
positive regulation of cartilage development GO:0061036 18 0.402
regulation of lens epithelial cell proliferation GO:2001109 1 0.399
response to organic cyclic compound GO:0014070 198 0.399
regulation of cytoskeleton organization GO:0051493 122 0.398
blastocyst development GO:0001824 80 0.397
muscle system process GO:0003012 141 0.397
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060829 1 0.396
submandibular salivary gland formation GO:0060661 1 0.395
hindbrain morphogenesis GO:0021575 46 0.394
regulation of smooth muscle cell differentiation GO:0051150 9 0.393
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.391
limbic system development GO:0021761 72 0.391
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.391

Zeb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.396
Human
disease of anatomical entity DOID:7 0 0.396
Human
eye and adnexa disease DOID:1492 0 0.396
Human
nervous system disease DOID:863 0 0.396
Human