IMP

Process View

Mus musculus

5 genes annotated in mouse

regulation of neuron maturation

Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of neuron maturation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of neuron maturation" (in gray)

Name	Description	Probability	Func Analog Organism
Tbx1	T-box 1	0.993	Mouse
Shh	sonic hedgehog	0.992
Fgfr2	fibroblast growth factor receptor 2	0.984
Prrx1	paired related homeobox 1	0.982
Eya1	eyes absent 1 homolog (Drosophila)	0.979
Pax3	paired box gene 3	0.976
Hoxa1	homeobox A1	0.967
Foxc2	forkhead box C2	0.959
Foxg1	forkhead box G1	0.952
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.950
Chrd	chordin	0.948
Foxc1	forkhead box C1	0.947
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.936
Tcfap2a	transcription factor AP-2, alpha	0.918
Pitx2	paired-like homeodomain transcription factor 2	0.911
Hand2	heart and neural crest derivatives expressed transcript 2	0.909
Fgfr1	fibroblast growth factor receptor 1	0.859
Fgf8	fibroblast growth factor 8	0.846
Bmp4	bone morphogenetic protein 4	0.833
Gli3	GLI-Kruppel family member GLI3	0.826
Sox9	SRY-box containing gene 9	0.821
Pax2	paired box gene 2	0.820
Dlx5	distal-less homeobox 5	0.806
Isl1	ISL1 transcription factor, LIM/homeodomain	0.769
Msx1	homeobox, msh-like 1	0.760
Otx2	orthodenticle homolog 2 (Drosophila)	0.724
Ntf3	neurotrophin 3	0.707	Mouse
Rarb	retinoic acid receptor, beta	0.705
Chd7	chromodomain helicase DNA binding protein 7	0.682
Smo	smoothened homolog (Drosophila)	0.660
Hand1	heart and neural crest derivatives expressed transcript 1	0.622
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.471
Tgfb2	transforming growth factor, beta 2	0.461
Rarg	retinoic acid receptor, gamma	0.454
Zeb1	zinc finger E-box binding homeobox 1	0.446
Hoxa3	homeobox A3	0.410
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.395
Vangl2	vang-like 2 (van gogh, Drosophila)	0.394
Bdnf	brain derived neurotrophic factor	0.389	Mouse
Gsc	goosecoid homeobox	0.336
Ednra	endothelin receptor type A	0.332	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.317
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.309
Jag1	jagged 1	0.299
Lrp6	low density lipoprotein receptor-related protein 6	0.283
Gbx2	gastrulation brain homeobox 2	0.262
Efnb2	ephrin B2	0.250
Vegfa	vascular endothelial growth factor A	0.234
Sox2	SRY-box containing gene 2	0.220
Rara	retinoic acid receptor, alpha	0.203
Ret	ret proto-oncogene	0.198
Ece1	endothelin converting enzyme 1	0.195
Msx2	homeobox, msh-like 2	0.188
Acvr1	activin A receptor, type 1	0.184
Wt1	Wilms tumor 1 homolog	0.148
Pitx1	paired-like homeodomain transcription factor 1	0.138
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.137
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.135
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.127
Bmp7	bone morphogenetic protein 7	0.127
Nrg1	neuregulin 1	0.120
Tbx3	T-box 3	0.108	Mouse
Mn1	meningioma 1	0.106
Pbx1	pre B-cell leukemia transcription factor 1	0.105
Axin1	axin 1	0.091
Prrx2	paired related homeobox 2	0.088
Tbx5	T-box 5	0.085	Mouse
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.083
Fgf10	fibroblast growth factor 10	0.077
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.075
Fgfr3	fibroblast growth factor receptor 3	0.070
Dlx2	distal-less homeobox 2	0.070
Zic3	zinc finger protein of the cerebellum 3	0.069
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.061
Foxi3	forkhead box I3	0.058
Hoxa2	homeobox A2	0.056
Psen1	presenilin 1	0.055
Sox11	SRY-box containing gene 11	0.053
Mesp1	mesoderm posterior 1	0.047
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.046
Nog	noggin	0.045
Runx2	runt related transcription factor 2	0.042
Bax	BCL2-associated X protein	0.041	Mouse
Gli2	GLI-Kruppel family member GLI2	0.039
Rxra	retinoid X receptor alpha	0.038
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.037
Dlx6	distal-less homeobox 6	0.035
Hoxb3	homeobox B3	0.035
Lef1	lymphoid enhancer binding factor 1	0.034
Pax9	paired box gene 9	0.033
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.029
Sox4	SRY-box containing gene 4	0.028
Otx1	orthodenticle homolog 1 (Drosophila)	0.028
Scn5a	sodium channel, voltage-gated, type V, alpha	0.028
Wnt3a	wingless-related MMTV integration site 3A	0.027
Gsk3b	glycogen synthase kinase 3 beta	0.027
Sox10	SRY-box containing gene 10	0.027
Tgfbr2	transforming growth factor, beta receptor II	0.027
Vti1a	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)	0.026
Apc	adenomatosis polyposis coli	0.025
Phox2b	paired-like homeobox 2b	0.025
Bmp2	bone morphogenetic protein 2	0.023
Gata3	GATA binding protein 3	0.023
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.022
Meox2	mesenchyme homeobox 2	0.022
Alx1	ALX homeobox 1	0.022
Phox2a	paired-like homeobox 2a	0.021
Nkx3-2	NK3 homeobox 2	0.020
Tbx10	T-box 10	0.020	Mouse
Mecom	MDS1 and EVI1 complex locus	0.019
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.019
Tcf21	transcription factor 21	0.018
Smad6	MAD homolog 6 (Drosophila)	0.016
Bmp5	bone morphogenetic protein 5	0.015
Nodal	nodal	0.015
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.015
Rdh10	retinol dehydrogenase 10 (all-trans)	0.015
Lrp5	low density lipoprotein receptor-related protein 5	0.014
Alx4	aristaless-like homeobox 4	0.013
Htt	huntingtin	0.013
Sall4	sal-like 4 (Drosophila)	0.013
Emx2	empty spiracles homolog 2 (Drosophila)	0.013
Lhx1	LIM homeobox protein 1	0.013
Wnt5a	wingless-related MMTV integration site 5A	0.013
Mitf	microphthalmia-associated transcription factor	0.013
Slc26a4	solute carrier family 26, member 4	0.013
Hmx3	H6 homeobox 3	0.012
Noto	notochord homolog (Xenopus laevis)	0.012
Bcl2	B-cell leukemia/lymphoma 2	0.012
Gdnf	glial cell line derived neurotrophic factor	0.012
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.012
Bak1	BCL2-antagonist/killer 1	0.012	Mouse
Hoxd3	homeobox D3	0.012
Fgfrl1	fibroblast growth factor receptor-like 1	0.011
Pax6	paired box gene 6	0.011
Lmx1a	LIM homeobox transcription factor 1 alpha	0.011
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.011
Nf1	neurofibromatosis 1	0.011
Ntf5	neurotrophin 5	0.011	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.011
Bcl6	B-cell leukemia/lymphoma 6	0.011
Epn1	epsin 1	0.011
Emx1	empty spiracles homolog 1 (Drosophila)	0.010