IMP
Process View
embryonic heart tube anterior posterior pattern specification
The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.
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Click on a gene's description to view its network relationships with genes known to be involved in "embryonic heart tube anterior posterior pattern specification"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 1.000 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | ||
| Foxc1 | forkhead box C1 | 1.000 | ||
| Gata4 | GATA binding protein 4 | 1.000 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 1.000 | ||
| Bmp4 | bone morphogenetic protein 4 | 1.000 | Mouse | |
| Fgf8 | fibroblast growth factor 8 | 1.000 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.999 | ||
| Pax3 | paired box gene 3 | 0.999 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.998 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.997 | ||
| Foxc2 | forkhead box C2 | 0.996 | ||
| Tbx1 | T-box 1 | 0.996 | ||
| Nodal | nodal | 0.996 | ||
| Jag1 | jagged 1 | 0.994 | ||
| Chrd | chordin | 0.993 | ||
| Rxra | retinoid X receptor alpha | 0.993 | ||
| Sox9 | SRY-box containing gene 9 | 0.991 | ||
| Gata6 | GATA binding protein 6 | 0.989 | Mouse | |
| Vegfa | vascular endothelial growth factor A | 0.988 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.986 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.982 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.975 | ||
| Pax2 | paired box gene 2 | 0.973 | ||
| Hoxa1 | homeobox A1 | 0.972 | ||
| Smo | smoothened homolog (Drosophila) | 0.964 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.961 | ||
| Rarg | retinoic acid receptor, gamma | 0.936 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.909 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.907 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.902 | ||
| Msx1 | homeobox, msh-like 1 | 0.897 | ||
| Acvr1 | activin A receptor, type 1 | 0.884 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.876 | ||
| Rarb | retinoic acid receptor, beta | 0.860 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.828 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.825 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.816 | ||
| Mesp1 | mesoderm posterior 1 | 0.802 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.798 | ||
| Prrx1 | paired related homeobox 1 | 0.783 | ||
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.697 | ||
| Ednra | endothelin receptor type A | 0.683 | ||
| Fgf10 | fibroblast growth factor 10 | 0.670 | ||
| Meox2 | mesenchyme homeobox 2 | 0.647 | ||
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.579 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.572 | ||
| Gsc | goosecoid homeobox | 0.570 | ||
| Zic3 | zinc finger protein of the cerebellum 3 | 0.521 | ||
| Foxg1 | forkhead box G1 | 0.517 | ||
| Zfpm2 | zinc finger protein, multitype 2 | 0.497 | ||
| Gbx2 | gastrulation brain homeobox 2 | 0.494 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.465 | ||
| Rara | retinoic acid receptor, alpha | 0.454 | ||
| Efnb2 | ephrin B2 | 0.454 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.434 | ||
| Dlx5 | distal-less homeobox 5 | 0.424 | ||
| Sox4 | SRY-box containing gene 4 | 0.408 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.397 | ||
| Ece1 | endothelin converting enzyme 1 | 0.397 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.368 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.355 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.335 | ||
| Ntf3 | neurotrophin 3 | 0.334 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.296 | ||
| Tbx3 | T-box 3 | 0.283 | ||
| Msx2 | homeobox, msh-like 2 | 0.275 | ||
| Ptch1 | patched homolog 1 | 0.267 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.261 | ||
| Gja1 | gap junction protein, alpha 1 | 0.252 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.208 | ||
| Egfr | epidermal growth factor receptor | 0.198 | ||
| Hoxa3 | homeobox A3 | 0.190 | ||
| Runx2 | runt related transcription factor 2 | 0.187 | ||
| Apc | adenomatosis polyposis coli | 0.171 | ||
| Nf1 | neurofibromatosis 1 | 0.155 | ||
| Lhx1 | LIM homeobox protein 1 | 0.126 | ||
| Dnahc5 | dynein, axonemal, heavy chain 5 | 0.120 | ||
| Psen1 | presenilin 1 | 0.108 | ||
| Klf3 | Kruppel-like factor 3 (basic) | 0.104 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.103 | ||
| Foxa2 | forkhead box A2 | 0.102 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.095 | ||
| Wt1 | Wilms tumor 1 homolog | 0.093 | ||
| Hoxa2 | homeobox A2 | 0.093 | ||
| Foxf1a | forkhead box F1a | 0.092 | ||
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.078 | ||
| Prrx2 | paired related homeobox 2 | 0.077 | ||
| Gata5 | GATA binding protein 5 | 0.073 | Mouse | |
| Alx4 | aristaless-like homeobox 4 | 0.072 | ||
| Klf1 | Kruppel-like factor 1 (erythroid) | 0.071 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.070 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.069 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.068 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.060 | ||
| Tcf21 | transcription factor 21 | 0.059 | ||
| Nog | noggin | 0.058 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.054 | ||
| Fgf3 | fibroblast growth factor 3 | 0.048 | ||
| Rhag | Rhesus blood group-associated A glycoprotein | 0.047 | ||
| Lefty1 | left right determination factor 1 | 0.045 | ||
| Tead3 | TEA domain family member 3 | 0.045 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.045 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.043 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.041 | ||
| Eomes | eomesodermin homolog (Xenopus laevis) | 0.040 | ||
| Rb1 | retinoblastoma 1 | 0.040 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.039 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.038 | ||
| Rdh10 | retinol dehydrogenase 10 (all-trans) | 0.038 | ||
| Pax8 | paired box gene 8 | 0.038 | ||
| Sox11 | SRY-box containing gene 11 | 0.038 | ||
| Kif3a | kinesin family member 3A | 0.036 | ||
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.036 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.034 | ||
| Alx1 | ALX homeobox 1 | 0.033 | ||
| Bmper | BMP-binding endothelial regulator | 0.032 | ||
| Cfc1 | cripto, FRL-1, cryptic family 1 | 0.032 | ||
| Sox2 | SRY-box containing gene 2 | 0.031 | ||
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.031 | ||
| Hhex | hematopoietically expressed homeobox | 0.030 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.030 | ||
| Pten | phosphatase and tensin homolog | 0.029 | ||
| Myl7 | myosin, light polypeptide 7, regulatory | 0.029 | ||
| Adam19 | a disintegrin and metallopeptidase domain 19 (meltrin beta) | 0.029 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.027 | ||
| Tdgf1 | teratocarcinoma-derived growth factor 1 | 0.027 | ||
| Mecom | MDS1 and EVI1 complex locus | 0.026 | ||
| Cdon | cell adhesion molecule-related/down-regulated by oncogenes | 0.026 | ||
| Mks1 | Meckel syndrome, type 1 | 0.025 | ||
| Acvr2b | activin receptor IIB | 0.025 | ||
| Smad2 | MAD homolog 2 (Drosophila) | 0.024 | ||
| Sall4 | sal-like 4 (Drosophila) | 0.024 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.024 | ||
| Gp1ba | glycoprotein 1b, alpha polypeptide | 0.023 | ||
| Ppara | peroxisome proliferator activated receptor alpha | 0.023 | ||
| Trp53 | transformation related protein 53 | 0.022 | ||
| Invs | inversin | 0.022 | ||
| Dll1 | delta-like 1 (Drosophila) | 0.022 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.021 | ||
| Gpc3 | glypican 3 | 0.021 | ||
| Wnt3a | wingless-related MMTV integration site 3A | 0.021 | ||
| Hoxd13 | homeobox D13 | 0.021 | ||
| Trap1a | tumor rejection antigen P1A | 0.021 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.019 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.019 | ||
| Hoxb4 | homeobox B4 | 0.019 | ||
| Dnahc11 | dynein, axonemal, heavy chain 11 | 0.019 | ||
| Tcof1 | Treacher Collins Franceschetti syndrome 1, homolog | 0.018 | ||
| Hoxa5 | homeobox A5 | 0.018 | ||
| Kcne1 | potassium voltage-gated channel, Isk-related subfamily, member 1 | 0.018 | ||
| Bmp5 | bone morphogenetic protein 5 | 0.017 | ||
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.017 | ||
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.017 | ||
| Kcnq1 | potassium voltage-gated channel, subfamily Q, member 1 | 0.017 | ||
| Tbx5 | T-box 5 | 0.016 | ||
| Ihh | Indian hedgehog | 0.016 | ||
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.016 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.016 | ||
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.015 | ||
| Mn1 | meningioma 1 | 0.015 | ||
| Hoxa13 | homeobox A13 | 0.015 | ||
| Hoxb3 | homeobox B3 | 0.015 | ||
| Igf2bp1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.015 | ||
| Hoxd11 | homeobox D11 | 0.015 | ||
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.014 | ||
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.014 | ||
| Fuz | fuzzy homolog (Drosophila) | 0.014 | ||
| Myo6 | myosin VI | 0.014 | ||
| Yap1 | yes-associated protein 1 | 0.014 | ||
| Tbx20 | T-box 20 | 0.013 | ||
| Efna1 | ephrin A1 | 0.013 | ||
| T | brachyury | 0.013 | ||
| Foxh1 | forkhead box H1 | 0.013 | ||
| Gata3 | GATA binding protein 3 | 0.013 | Mouse | |
| Ift88 | intraflagellar transport 88 homolog (Chlamydomonas) | 0.013 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.012 | ||
| Hesx1 | homeobox gene expressed in ES cells | 0.012 | ||
| Gdf3 | growth differentiation factor 3 | 0.012 | Mouse | |
| Sox7 | SRY-box containing gene 7 | 0.012 | ||
| Hbb-bh1 | hemoglobin Z, beta-like embryonic chain | 0.012 | ||
| P2rx1 | purinergic receptor P2X, ligand-gated ion channel, 1 | 0.011 | ||
| Epha1 | Eph receptor A1 | 0.011 | ||
| Disp1 | dispatched homolog 1 (Drosophila) | 0.011 | ||
| She | src homology 2 domain-containing transforming protein E | 0.011 | ||
| Zfpm1 | zinc finger protein, multitype 1 | 0.011 | ||
| Plac1 | placental specific protein 1 | 0.011 | ||
| Efnb1 | ephrin B1 | 0.011 | ||
| Gja5 | gap junction protein, alpha 5 | 0.011 | ||
| Pax9 | paired box gene 9 | 0.011 | ||
| Itga8 | integrin alpha 8 | 0.011 | ||
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.010 | ||
| Itga3 | integrin alpha 3 | 0.010 | ||
| Alx3 | aristaless-like homeobox 3 | 0.010 |