IMP

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Mus musculus

1 genes annotated in mouse

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axial mesodermal cell fate commitment

GO:0048322

The process in which a cell becomes committed to become an axial mesoderm cell.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "axial mesodermal cell fate commitment"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "axial mesodermal cell fate commitment" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Bmp4	bone morphogenetic protein 4	1.000
Foxc1	forkhead box C1	1.000
Gli3	GLI-Kruppel family member GLI3	1.000
Msx1	homeobox, msh-like 1	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Bmp7	bone morphogenetic protein 7	0.999	Mouse
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.999
Hand1	heart and neural crest derivatives expressed transcript 1	0.999
Pitx2	paired-like homeodomain transcription factor 2	0.999
Smo	smoothened homolog (Drosophila)	0.998
Prrx1	paired related homeobox 1	0.996
Otx2	orthodenticle homolog 2 (Drosophila)	0.996
Gli2	GLI-Kruppel family member GLI2	0.993
Fgf8	fibroblast growth factor 8	0.992
Msx2	homeobox, msh-like 2	0.987
Hand2	heart and neural crest derivatives expressed transcript 2	0.981
Foxc2	forkhead box C2	0.978
Fgfr1	fibroblast growth factor receptor 1	0.977
Fgfr3	fibroblast growth factor receptor 3	0.976
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.976
Sox9	SRY-box containing gene 9	0.975
Foxh1	forkhead box H1	0.974	Zebrafish
Tgfb2	transforming growth factor, beta 2	0.969
Zic3	zinc finger protein of the cerebellum 3	0.964
Vangl2	vang-like 2 (van gogh, Drosophila)	0.959
Chrd	chordin	0.959
Zeb1	zinc finger E-box binding homeobox 1	0.950
Dlx5	distal-less homeobox 5	0.948
Tbx1	T-box 1	0.948
Ednra	endothelin receptor type A	0.937
Gsc	goosecoid homeobox	0.933
Pax3	paired box gene 3	0.915
Pax2	paired box gene 2	0.900
Dnahc11	dynein, axonemal, heavy chain 11	0.886
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.848
Mks1	Meckel syndrome, type 1	0.813
Ptch1	patched homolog 1	0.800
Prrx2	paired related homeobox 2	0.779
Eya1	eyes absent 1 homolog (Drosophila)	0.769
Gdf1	growth differentiation factor 1	0.757
Tcfap2a	transcription factor AP-2, alpha	0.730
Alx4	aristaless-like homeobox 4	0.723
Tbx15	T-box 15	0.708
Nodal	nodal	0.685
Foxj1	forkhead box J1	0.658
Lhx1	LIM homeobox protein 1	0.658
Kif3a	kinesin family member 3A	0.655
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.646
Alx1	ALX homeobox 1	0.616
Cfc1	cripto, FRL-1, cryptic family 1	0.590
Bmp2	bone morphogenetic protein 2	0.573
Runx2	runt related transcription factor 2	0.572
Hoxd13	homeobox D13	0.514
Lrp6	low density lipoprotein receptor-related protein 6	0.481
Meox2	mesenchyme homeobox 2	0.449
Gdf3	growth differentiation factor 3	0.447
Gas1	growth arrest specific 1	0.427
Rarg	retinoic acid receptor, gamma	0.410
Gdf6	growth differentiation factor 6	0.329	Mouse
Lmx1b	LIM homeobox transcription factor 1 beta	0.328
Gata4	GATA binding protein 4	0.306
Ctnnb1	catenin (cadherin associated protein), beta 1	0.303
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.297
Bmper	BMP-binding endothelial regulator	0.282
Apc	adenomatosis polyposis coli	0.261
Gdf5	growth differentiation factor 5	0.254	Mouse
Rarb	retinoic acid receptor, beta	0.252
Wnt3a	wingless-related MMTV integration site 3A	0.236
Alx3	aristaless-like homeobox 3	0.216
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.214
Fgfrl1	fibroblast growth factor receptor-like 1	0.212
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.195
Nog	noggin	0.186
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.186
Invs	inversin	0.179
Pbx1	pre B-cell leukemia transcription factor 1	0.163
Lefty1	left right determination factor 1	0.161
Bmp5	bone morphogenetic protein 5	0.149	Mouse
Dnahc5	dynein, axonemal, heavy chain 5	0.146
Pax9	paired box gene 9	0.134
Hoxa13	homeobox A13	0.134
Gdf7	growth differentiation factor 7	0.132	Mouse
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.114
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.114
Mn1	meningioma 1	0.113
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.110
Col2a1	collagen, type II, alpha 1	0.107
Tdgf1	teratocarcinoma-derived growth factor 1	0.095
Smad6	MAD homolog 6 (Drosophila)	0.083
Acvr1	activin A receptor, type 1	0.083
Pthlh	parathyroid hormone-like peptide	0.082
Tbx3	T-box 3	0.072
Ret	ret proto-oncogene	0.071
Foxa2	forkhead box A2	0.069
Tbx6	T-box 6	0.067
Cldn6	claudin 6	0.066
Jag1	jagged 1	0.064
Wt1	Wilms tumor 1 homolog	0.064
T	brachyury	0.063
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.061
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.060
Eomes	eomesodermin homolog (Xenopus laevis)	0.056
Emid2	EMI domain containing 2	0.056
Npr2	natriuretic peptide receptor 2	0.052
Ihh	Indian hedgehog	0.051
Gbx2	gastrulation brain homeobox 2	0.051
Disp1	dispatched homolog 1 (Drosophila)	0.051
Hoxb3	homeobox B3	0.050
Smad3	MAD homolog 3 (Drosophila)	0.048
En1	engrailed 1	0.047
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.046
Hoxa11	homeobox A11	0.044
Lefty2	left-right determination factor 2	0.043
Acvr2b	activin receptor IIB	0.042
Gata6	GATA binding protein 6	0.041
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.040
Pitx1	paired-like homeodomain transcription factor 1	0.040
Ybx2	Y box protein 2	0.038
Smad4	MAD homolog 4 (Drosophila)	0.038
Cer1	cerberus 1 homolog (Xenopus laevis)	0.038
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.038
Wnt6	wingless-related MMTV integration site 6	0.037
Sox11	SRY-box containing gene 11	0.037
Sall4	sal-like 4 (Drosophila)	0.036
Fgf15	fibroblast growth factor 15	0.035
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.034
Il13	interleukin 13	0.033
Lrp2	low density lipoprotein receptor-related protein 2	0.032
Fgf9	fibroblast growth factor 9	0.032
Oprm1	opioid receptor, mu 1	0.032
Wnt5a	wingless-related MMTV integration site 5A	0.031
Rln1	relaxin 1	0.030
Cilp2	cartilage intermediate layer protein 2	0.030
Tgfbr2	transforming growth factor, beta receptor II	0.030
Foxg1	forkhead box G1	0.030
Sox3	SRY-box containing gene 3	0.030
Cnga3	cyclic nucleotide gated channel alpha 3	0.030
Hoxd11	homeobox D11	0.029
Foxf1a	forkhead box F1a	0.029
Cdx2	caudal type homeobox 2	0.029
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.029
Foxf2	forkhead box F2	0.028
Dlx6	distal-less homeobox 6	0.028
Pax8	paired box gene 8	0.028
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.028
Itga3	integrin alpha 3	0.028
Lef1	lymphoid enhancer binding factor 1	0.027
Dlx2	distal-less homeobox 2	0.027
She	src homology 2 domain-containing transforming protein E	0.026
Gli1	GLI-Kruppel family member GLI1	0.026
Hoxa1	homeobox A1	0.026
Rhox6	reproductive homeobox 6	0.025
Isl1	ISL1 transcription factor, LIM/homeodomain	0.025
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.025
Wnt3	wingless-related MMTV integration site 3	0.024
Tcfap2c	transcription factor AP-2, gamma	0.024
Syt9	synaptotagmin IX	0.024
Fgf5	fibroblast growth factor 5	0.023
Wnt8a	wingless-related MMTV integration site 8A	0.023
Otx1	orthodenticle homolog 1 (Drosophila)	0.023
Evx1	even skipped homeotic gene 1 homolog	0.022
Gpc3	glypican 3	0.022
Col4a3	collagen, type IV, alpha 3	0.022
Tcl1	T-cell lymphoma breakpoint 1	0.022
Lmx1a	LIM homeobox transcription factor 1 alpha	0.022
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.021
Pnliprp2	pancreatic lipase-related protein 2	0.021
Fgf17	fibroblast growth factor 17	0.021
Tulp1	tubby like protein 1	0.021
Krt72-ps	keratin 72, pseudogene	0.021
Btbd17	BTB (POZ) domain containing 17	0.020
Fgf10	fibroblast growth factor 10	0.020
Sfrp2	secreted frizzled-related protein 2	0.020
Efna4	ephrin A4	0.020
Hesx1	homeobox gene expressed in ES cells	0.020
Fmn1	formin 1	0.020
Tcf15	transcription factor 15	0.020
En2	engrailed 2	0.019
Fgf3	fibroblast growth factor 3	0.019
Rpgrip1l	Rpgrip1-like	0.019
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.019
Pkd1	polycystic kidney disease 1 homolog	0.019
Tecta	tectorin alpha	0.018
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.018
Pax1	paired box gene 1	0.018
Utf1	undifferentiated embryonic cell transcription factor 1	0.018
Prop1	paired like homeodomain factor 1	0.018
Sox17	SRY-box containing gene 17	0.018
Tcf21	transcription factor 21	0.018
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.018
Efnb2	ephrin B2	0.018
Mybph	myosin binding protein H	0.017
Tbx2	T-box 2	0.017
Phox2b	paired-like homeobox 2b	0.017
Crxos1	Crx opposite strand transcript 1	0.017
Psen1	presenilin 1	0.017
6030429G01Rik	RIKEN cDNA 6030429G01 gene	0.016
Osta	organic solute transporter alpha	0.016
Hoxa2	homeobox A2	0.016
Twist2	twist homolog 2 (Drosophila)	0.016
Gja3	gap junction protein, alpha 3	0.016
Ptprb	protein tyrosine phosphatase, receptor type, B	0.016
Crhr2	corticotropin releasing hormone receptor 2	0.016
Hoxa10	homeobox A10	0.016
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.016
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.015
Dmrt1	doublesex and mab-3 related transcription factor 1	0.015
Sox7	SRY-box containing gene 7	0.015
Ntf3	neurotrophin 3	0.015
Gata5	GATA binding protein 5	0.015
Pten	phosphatase and tensin homolog	0.015
Ptk7	PTK7 protein tyrosine kinase 7	0.014
Adra2b	adrenergic receptor, alpha 2b	0.014
Zfp503	zinc finger protein 503	0.014
Emx2	empty spiracles homolog 2 (Drosophila)	0.014
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.014
Ppap2b	phosphatidic acid phosphatase type 2B	0.014
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.014
Htra1	HtrA serine peptidase 1	0.014
Nos3	nitric oxide synthase 3, endothelial cell	0.014
Cdx1	caudal type homeobox 1	0.014
Foxd3	forkhead box D3	0.014
Wnt1	wingless-related MMTV integration site 1	0.014
Nkx3-2	NK3 homeobox 2	0.014
Hoxd3	homeobox D3	0.013
Npr3	natriuretic peptide receptor 3	0.013
Col13a1	collagen, type XIII, alpha 1	0.013
Pkd2	polycystic kidney disease 2	0.013
Sox1	SRY-box containing gene 1	0.013
B4galnt2	beta-1,4-N-acetyl-galactosaminyl transferase 2	0.013
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.013
Dlx4	distal-less homeobox 4	0.013
Barx1	BarH-like homeobox 1	0.013
Kremen2	kringle containing transmembrane protein 2	0.013
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.013
Hes3	hairy and enhancer of split 3 (Drosophila)	0.013
Olfr1508	olfactory receptor 1508	0.012
Clcnka	chloride channel Ka	0.012
Bmp8b	bone morphogenetic protein 8b	0.012	Mouse
Sost	sclerostin	0.012
Amhr2	anti-Mullerian hormone type 2 receptor	0.012
Cdk5r2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.012
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.012
Twist1	twist homolog 1 (Drosophila)	0.012
Matn3	matrilin 3	0.012
Bicc1	bicaudal C homolog 1 (Drosophila)	0.012
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.012
Gcm1	glial cells missing homolog 1 (Drosophila)	0.012
Hoxa9	homeobox A9	0.012
Hoxb1	homeobox B1	0.012
Pgap1	post-GPI attachment to proteins 1	0.012
Tek	endothelial-specific receptor tyrosine kinase	0.012
Ccdc85c	coiled-coil domain containing 85C	0.012
Vegfa	vascular endothelial growth factor A	0.011
Chd7	chromodomain helicase DNA binding protein 7	0.011
Gja1	gap junction protein, alpha 1	0.011
Sel1l2	sel-1 suppressor of lin-12-like 2 (C. elegans)	0.011
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.011
Fgf18	fibroblast growth factor 18	0.011
Fam171a1	family with sequence similarity 171, member A1	0.011
Rem1	rad and gem related GTP binding protein 1	0.011
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.011
Hdgfl1	hepatoma derived growth factor-like 1	0.011
Foxd2	forkhead box D2	0.011
Gabrr1	gamma-aminobutyric acid (GABA) C receptor, subunit rho 1	0.011
Itga8	integrin alpha 8	0.011
Gm711	predicted gene 711	0.011
Tsks	testis-specific serine kinase substrate	0.011
Krtap6-3	keratin associated protein 6-3	0.011
Irs3	insulin receptor substrate 3	0.011
Mpl	myeloproliferative leukemia virus oncogene	0.011
Abca17	ATP-binding cassette, sub-family A (ABC1), member 17	0.011
Htr1f	5-hydroxytryptamine (serotonin) receptor 1F	0.010
Tsx	testis specific X-linked gene	0.010
Dpep3	dipeptidase 3	0.010
Padi3	peptidyl arginine deiminase, type III	0.010
Tex21	testis expressed gene 21	0.010
Aym1	activator of yeast meiotic promoters 1	0.010
Foxe1	forkhead box E1	0.010
Smad2	MAD homolog 2 (Drosophila)	0.010
Msmb	beta-microseminoprotein	0.010
Hoxd9	homeobox D9	0.010
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.010