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Homo sapiens

10 genes annotated in human

granulocyte activation

The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "granulocyte activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "granulocyte activation" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	1.000	Human
CCL5	chemokine (C-C motif) ligand 5	0.906
SYK	spleen tyrosine kinase	0.729	Mouse
PRKCZ	protein kinase C, zeta	0.686	Human
CCL4	chemokine (C-C motif) ligand 4	0.564	Human
IL2RB	interleukin 2 receptor, beta	0.509
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.459
IFNG	interferon, gamma	0.438
CXCL9	chemokine (C-X-C motif) ligand 9	0.362
SNAP23	synaptosomal-associated protein, 23kDa	0.336
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.275
CCR4	chemokine (C-C motif) receptor 4	0.274	Human
CCR2	chemokine (C-C motif) receptor 2	0.241	Human Mouse
CCL22	chemokine (C-C motif) ligand 22	0.220	Human
NCF1	neutrophil cytosolic factor 1	0.211
PPL	periplakin	0.163
CCL3	chemokine (C-C motif) ligand 3	0.162
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.150
NOXA1	NADPH oxidase activator 1	0.136
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.123
CCL8	chemokine (C-C motif) ligand 8	0.121	Human
CCR7	chemokine (C-C motif) receptor 7	0.118	Human
CCL19	chemokine (C-C motif) ligand 19	0.103	Human
DPP4	dipeptidyl-peptidase 4	0.100
CCL7	chemokine (C-C motif) ligand 7	0.084	Human
IL1B	interleukin 1, beta	0.080
UBASH3B	ubiquitin associated and SH3 domain containing B	0.067
CCL2	chemokine (C-C motif) ligand 2	0.066	Human
CCR1	chemokine (C-C motif) receptor 1	0.059	Human
TFF1	trefoil factor 1	0.058
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.055
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.051	Human
CXCL13	chemokine (C-X-C motif) ligand 13	0.048
CCL13	chemokine (C-C motif) ligand 13	0.045	Human
IL10	interleukin 10	0.041
ANKRD27	ankyrin repeat domain 27 (VPS9 domain)	0.039
ANXA2	annexin A2	0.037
BTK	Bruton agammaglobulinemia tyrosine kinase	0.037
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.036
SIRPB1	signal-regulatory protein beta 1	0.032
ZNF71	zinc finger protein 71	0.032
VCAM1	vascular cell adhesion molecule 1	0.028
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.028
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.028
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.027
IGSF6	immunoglobulin superfamily, member 6	0.027
TNF	tumor necrosis factor	0.026
TLR2	toll-like receptor 2	0.025
S100A11	S100 calcium binding protein A11	0.023
NUMB	numb homolog (Drosophila)	0.023
CCDC115	coiled-coil domain containing 115	0.022
APBA3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.022
IL10RA	interleukin 10 receptor, alpha	0.021
KRT8	keratin 8	0.021
S100A10	S100 calcium binding protein A10	0.020
PDPK1	3-phosphoinositide dependent protein kinase-1	0.020
CAV1	caveolin 1, caveolae protein, 22kDa	0.020
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.020
IL8	interleukin 8	0.020
RGS1	regulator of G-protein signaling 1	0.019
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.019
CD86	CD86 molecule	0.019
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.018
CXCL10	chemokine (C-X-C motif) ligand 10	0.018
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.018
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.017
CDCP1	CUB domain containing protein 1	0.017
BLNK	B-cell linker	0.016
CXCR6	chemokine (C-X-C motif) receptor 6	0.016	Human
IRF4	interferon regulatory factor 4	0.016
CLEC10A	C-type lectin domain family 10, member A	0.016
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.016
CXCL11	chemokine (C-X-C motif) ligand 11	0.016
SH3RF1	SH3 domain containing ring finger 1	0.016
CD40LG	CD40 ligand	0.016
CD2	CD2 molecule	0.015
SLAMF7	SLAM family member 7	0.015
CXCR3	chemokine (C-X-C motif) receptor 3	0.015	Human
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.015
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.015
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.014
TRIM9	tripartite motif containing 9	0.014
BAG3	BCL2-associated athanogene 3	0.014
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.014
RNASE6	ribonuclease, RNase A family, k6	0.013
GZMK	granzyme K (granzyme 3; tryptase II)	0.013
NCF4	neutrophil cytosolic factor 4, 40kDa	0.013
NKG7	natural killer cell group 7 sequence	0.013
F11R	F11 receptor	0.013
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.013
IDE	insulin-degrading enzyme	0.013
PRKCB	protein kinase C, beta	0.013
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.013
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.013
CCR6	chemokine (C-C motif) receptor 6	0.012	Human
ANXA1	annexin A1	0.012	Human
CXCR2	chemokine (C-X-C motif) receptor 2	0.012
CARD11	caspase recruitment domain family, member 11	0.012
ADAMDEC1	ADAM-like, decysin 1	0.012
CYBA	cytochrome b-245, alpha polypeptide	0.012
CD163	CD163 molecule	0.012
FPR3	formyl peptide receptor 3	0.011
CLEC7A	C-type lectin domain family 7, member A	0.011
CCR3	chemokine (C-C motif) receptor 3	0.010	Human
CLEC4A	C-type lectin domain family 4, member A	0.010
LAG3	lymphocyte-activation gene 3	0.010
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.010
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.010
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.010
CD83	CD83 molecule	0.010