IMP

Process View

Homo sapiens

14 genes annotated in human

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water homeostasis

GO:0030104

Any process involved in the maintenance of an internal steady state of water within an organism or cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "water homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "water homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
TACSTD2	tumor-associated calcium signal transducer 2	0.996
RORA	RAR-related orphan receptor A	0.992
SMN1	survival of motor neuron 1, telomeric	0.985
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.982
SOX10	SRY (sex determining region Y)-box 10	0.982
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.969
KRT5	keratin 5	0.954
PAX3	paired box 3	0.878
CTNND1	catenin (cadherin-associated protein), delta 1	0.783
ATP13A2	ATPase type 13A2	0.621
MKL1	megakaryoblastic leukemia (translocation) 1	0.526
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.450
HMOX2	heme oxygenase (decycling) 2	0.419
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.375
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.352
ADAMTSL4	ADAMTS-like 4	0.336
MYOCD	myocardin	0.302
TJP3	tight junction protein 3 (zona occludens 3)	0.297
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.280
INADL	InaD-like (Drosophila)	0.241
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.225
SATB2	SATB homeobox 2	0.187
SPDEF	SAM pointed domain containing ets transcription factor	0.165
CABLES1	Cdk5 and Abl enzyme substrate 1	0.160
MYOG	myogenin (myogenic factor 4)	0.141
KCTD17	potassium channel tetramerisation domain containing 17	0.111
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.108
EPN1	epsin 1	0.100
FAM107A	family with sequence similarity 107, member A	0.096
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.092
CLDN3	claudin 3	0.086	Human
MEOX2	mesenchyme homeobox 2	0.084
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.075	Human
MDFI	MyoD family inhibitor	0.073
RHOXF2	Rhox homeobox family, member 2	0.072
CLDN16	claudin 16	0.067	Human
KRT6C	keratin 6C	0.062
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.059
CLDN4	claudin 4	0.054
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.050
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.049
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.046
GLTPD1	glycolipid transfer protein domain containing 1	0.044
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.042
TMEM40	transmembrane protein 40	0.042
KRTAP4-12	keratin associated protein 4-12	0.041
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.039	Human
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.038
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	0.037
MYOD1	myogenic differentiation 1	0.037
SCGB1A1	secretoglobin, family 1A, member 1 (uteroglobin)	0.036
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.036
LYPD3	LY6/PLAUR domain containing 3	0.032
SPINT1	serine peptidase inhibitor, Kunitz type 1	0.031
SFTPB	surfactant protein B	0.031
EP300	E1A binding protein p300	0.031
HOXA1	homeobox A1	0.031
PGR	progesterone receptor	0.029
ALOX15B	arachidonate 15-lipoxygenase, type B	0.028
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.028
ALOX12B	arachidonate 12-lipoxygenase, 12R type	0.027
PKP3	plakophilin 3	0.027
FRMD5	FERM domain containing 5	0.026
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.026	Human
AP1M2	adaptor-related protein complex 1, mu 2 subunit	0.026
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.024
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.024
WFDC2	WAP four-disulfide core domain 2	0.024
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.023
SOX21	SRY (sex determining region Y)-box 21	0.023
EEF2K	eukaryotic elongation factor-2 kinase	0.023
FAT2	FAT tumor suppressor homolog 2 (Drosophila)	0.022
KLK5	kallikrein-related peptidase 5	0.022
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.022
TMPRSS2	transmembrane protease, serine 2	0.022
ST14	suppression of tumorigenicity 14 (colon carcinoma)	0.022
PAX8	paired box 8	0.021
TMEM30B	transmembrane protein 30B	0.021
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.021
IRF6	interferon regulatory factor 6	0.021
SLC17A1	solute carrier family 17 (sodium phosphate), member 1	0.020
CLDN7	claudin 7	0.020	Human
POU3F4	POU class 3 homeobox 4	0.020	Worm
SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.019
PSEN1	presenilin 1	0.019
LAD1	ladinin 1	0.019
MUC1	mucin 1, cell surface associated	0.018
RBM11	RNA binding motif protein 11	0.018
KLK13	kallikrein-related peptidase 13	0.018
CYP4F8	cytochrome P450, family 4, subfamily F, polypeptide 8	0.018	Human
CLEC3B	C-type lectin domain family 3, member B	0.018
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.018
TBX6	T-box 6	0.018
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.017
LINGO1	leucine rich repeat and Ig domain containing 1	0.017
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.017	Human
PRSS8	protease, serine, 8	0.017
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.017
RAMP3	receptor (G protein-coupled) activity modifying protein 3	0.017
CLCA2	chloride channel accessory 2	0.017
NAT15	N-acetyltransferase 15 (GCN5-related, putative)	0.016
CCNK	cyclin K	0.016
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.016
PCDH1	protocadherin 1	0.016
KLK11	kallikrein-related peptidase 11	0.016
SIRT7	sirtuin 7	0.016
S1PR5	sphingosine-1-phosphate receptor 5	0.015
PLEKHA7	pleckstrin homology domain containing, family A member 7	0.015
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.015
YAP1	Yes-associated protein 1	0.015
PRODH2	proline dehydrogenase (oxidase) 2	0.015
BRAP	BRCA1 associated protein	0.015
CLDN19	claudin 19	0.014	Human
SLURP1	secreted LY6/PLAUR domain containing 1	0.014
HES2	hairy and enhancer of split 2 (Drosophila)	0.014
MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.014
SEC16A	SEC16 homolog A (S. cerevisiae)	0.014
GPRIN2	G protein regulated inducer of neurite outgrowth 2	0.013
LLGL2	lethal giant larvae homolog 2 (Drosophila)	0.013
HNRNPCL1	heterogeneous nuclear ribonucleoprotein C-like 1	0.013
MAT1A	methionine adenosyltransferase I, alpha	0.013
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.013
GPR87	G protein-coupled receptor 87	0.013
HGD	homogentisate 1,2-dioxygenase	0.013
KRT4	keratin 4	0.013
ATP12A	ATPase, H+/K+ transporting, nongastric, alpha polypeptide	0.013
FGFR1	fibroblast growth factor receptor 1	0.013
FAM124B	family with sequence similarity 124B	0.013
USP2	ubiquitin specific peptidase 2	0.013
ATG2A	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.013
AGR2	anterior gradient homolog 2 (Xenopus laevis)	0.012
RNF11	ring finger protein 11	0.012
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.012
KRT8	keratin 8	0.012
PRLR	prolactin receptor	0.012
UCP1	uncoupling protein 1 (mitochondrial, proton carrier)	0.012
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.012
GSTA3	glutathione S-transferase alpha 3	0.012
NIPSNAP3A	nipsnap homolog 3A (C. elegans)	0.012
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.012
LECT1	leukocyte cell derived chemotaxin 1	0.011
POU2F3	POU class 2 homeobox 3	0.011
DUOX1	dual oxidase 1	0.011
IL1F9	interleukin 1 family, member 9	0.011
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	0.011
ORM1	orosomucoid 1	0.011
DPEP1	dipeptidase 1 (renal)	0.011
CLDN5	claudin 5	0.011	Human
PRSS22	protease, serine, 22	0.011
TGM3	transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.011
ABO	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	0.011
EXT2	exostosin 2	0.011
BCL2	B-cell CLL/lymphoma 2	0.011
C8A	complement component 8, alpha polypeptide	0.011
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.011
ATP6V0A4	ATPase, H+ transporting, lysosomal V0 subunit a4	0.011
CALCA	calcitonin-related polypeptide alpha	0.011
KLK6	kallikrein-related peptidase 6	0.011
TJP1	tight junction protein 1 (zona occludens 1)	0.011
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.011
ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	0.011
PIP	prolactin-induced protein	0.011
GATA4	GATA binding protein 4	0.010
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.010
FOXN1	forkhead box N1	0.010
KRT13	keratin 13	0.010
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	0.010
DAO	D-amino-acid oxidase	0.010
ARG1	arginase, liver	0.010
LY6D	lymphocyte antigen 6 complex, locus D	0.010
UMOD	uromodulin	0.010
POU3F2	POU class 3 homeobox 2	0.010	Worm
PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.010