IMP

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Homo sapiens

3 genes annotated in human

epoxygenase p450 pathway

GO:0019373

The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "epoxygenase p450 pathway"

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Name	Description	Probability	Func Analog Organism
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	1.000	Human
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	1.000
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.989	Human
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.948
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.947
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.929
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.872	Human
ADH6	alcohol dehydrogenase 6 (class V)	0.815
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.779
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.704	Human
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.660	Human Rat
GLYAT	glycine-N-acyltransferase	0.498
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.498
C8B	complement component 8, beta polypeptide	0.455
MAT1A	methionine adenosyltransferase I, alpha	0.414
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.404
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.380	Human
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.342
C8A	complement component 8, alpha polypeptide	0.324
C6	complement component 6	0.293
OTC	ornithine carbamoyltransferase	0.262
FETUB	fetuin B	0.259
AGXT2	alanine--glyoxylate aminotransferase 2	0.243
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.243	Human
ALDOB	aldolase B, fructose-bisphosphate	0.228
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.223
HRG	histidine-rich glycoprotein	0.218
FMO4	flavin containing monooxygenase 4	0.209
G6PC	glucose-6-phosphatase, catalytic subunit	0.201
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.200
CFHR4	complement factor H-related 4	0.195
CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	0.193	Human
DAO	D-amino-acid oxidase	0.184
F9	coagulation factor IX	0.157
AADAC	arylacetamide deacetylase (esterase)	0.153
HAL	histidine ammonia-lyase	0.130
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.125
KNG1	kininogen 1	0.125
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.124	Human
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.120	Human
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.116
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.114
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.112
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.107
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.097
GSTA3	glutathione S-transferase alpha 3	0.094
C4BPA	complement component 4 binding protein, alpha	0.092
LAMC3	laminin, gamma 3	0.092
BHMT	betaine--homocysteine S-methyltransferase	0.092
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.091	Human
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.086
PLG	plasminogen	0.083
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.081
CA5A	carbonic anhydrase VA, mitochondrial	0.081
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.077
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.072
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.071
F13B	coagulation factor XIII, B polypeptide	0.071
DIO1	deiodinase, iodothyronine, type I	0.068
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.067
HPX	hemopexin	0.061
APCS	amyloid P component, serum	0.060
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.060
HPD	4-hydroxyphenylpyruvate dioxygenase	0.059
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.058
MASP2	mannan-binding lectin serine peptidase 2	0.057
ADRA1A	adrenergic, alpha-1A-, receptor	0.057
RDH16	retinol dehydrogenase 16 (all-trans)	0.056
DNASE1L3	deoxyribonuclease I-like 3	0.055
UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15	0.055
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.053
CNGA1	cyclic nucleotide gated channel alpha 1	0.052
XDH	xanthine dehydrogenase	0.051
HGD	homogentisate 1,2-dioxygenase	0.050
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.049
DPYS	dihydropyrimidinase	0.046
MTTP	microsomal triglyceride transfer protein	0.046
APOC3	apolipoprotein C-III	0.045
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.045
TTPA	tocopherol (alpha) transfer protein	0.044
ARG1	arginase, liver	0.043
LECT2	leukocyte cell-derived chemotaxin 2	0.043
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.042
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.041
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.041
PAH	phenylalanine hydroxylase	0.041
KRT4	keratin 4	0.040
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.040
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.040
LPA	lipoprotein, Lp(a)	0.039
ANXA10	annexin A10	0.039
FABP1	fatty acid binding protein 1, liver	0.039
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.038
ADH4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.037
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.037
MEP1B	meprin A, beta	0.037
CCL16	chemokine (C-C motif) ligand 16	0.037
APOC4	apolipoprotein C-IV	0.037
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.037
UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1	0.037
AFM	afamin	0.035
COLEC10	collectin sub-family member 10 (C-type lectin)	0.035
GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	0.034
C9	complement component 9	0.033
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.033
RNF32	ring finger protein 32	0.032
IL22RA1	interleukin 22 receptor, alpha 1	0.032
F11	coagulation factor XI	0.032
A1CF	APOBEC1 complementation factor	0.031
CPB2	carboxypeptidase B2 (plasma)	0.031
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.030	Human
GYS2	glycogen synthase 2 (liver)	0.030
CRP	C-reactive protein, pentraxin-related	0.030
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.030
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.029
MUC3A	mucin 3A, cell surface associated	0.029
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.029
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.028
TMC5	transmembrane channel-like 5	0.028
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.028
C9orf68	chromosome 9 open reading frame 68	0.027
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.027
PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide	0.027
HABP2	hyaluronan binding protein 2	0.026
NR1I3	nuclear receptor subfamily 1, group I, member 3	0.026
CYP4F8	cytochrome P450, family 4, subfamily F, polypeptide 8	0.026	Human
UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17	0.025
UGT1A9	UDP glucuronosyltransferase 1 family, polypeptide A9	0.025
HNF4A	hepatocyte nuclear factor 4, alpha	0.025
ENTPD5	ectonucleoside triphosphate diphosphohydrolase 5	0.025
PZP	pregnancy-zone protein	0.025
MAST1	microtubule associated serine/threonine kinase 1	0.025
EPHX2	epoxide hydrolase 2, cytoplasmic	0.025
ATP10B	ATPase, class V, type 10B	0.024
APOF	apolipoprotein F	0.024
PON1	paraoxonase 1	0.024
TMPRSS6	transmembrane protease, serine 6	0.022
DEFB1	defensin, beta 1	0.022
LRRC31	leucine rich repeat containing 31	0.022
PIPOX	pipecolic acid oxidase	0.022
TAT	tyrosine aminotransferase	0.022
C4BPB	complement component 4 binding protein, beta	0.022
PNLIPRP1	pancreatic lipase-related protein 1	0.022
TM4SF4	transmembrane 4 L six family member 4	0.021
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.021
CIDEB	cell death-inducing DFFA-like effector b	0.021
SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	0.021
ACE2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	0.021
HAO2	hydroxyacid oxidase 2 (long chain)	0.020
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.019
ACRV1	acrosomal vesicle protein 1	0.019
PLA2G1B	phospholipase A2, group IB (pancreas)	0.019
CES3	carboxylesterase 3	0.019
C8G	complement component 8, gamma polypeptide	0.019
CDH17	cadherin 17, LI cadherin (liver-intestine)	0.019
KLK13	kallikrein-related peptidase 13	0.019
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.018
ANGPTL3	angiopoietin-like 3	0.018
C14orf105	chromosome 14 open reading frame 105	0.018
CYP4A22	cytochrome P450, family 4, subfamily A, polypeptide 22	0.018	Human
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	0.018
CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1	0.017
CLCA4	chloride channel accessory 4	0.017
PON3	paraoxonase 3	0.017
RAB3D	RAB3D, member RAS oncogene family	0.017
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.017
KRT13	keratin 13	0.017
FAM164C	family with sequence similarity 164, member C	0.017
CD5L	CD5 molecule-like	0.017
FGL1	fibrinogen-like 1	0.017
BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	0.017
SLC17A3	solute carrier family 17 (sodium phosphate), member 3	0.016
MOGAT2	monoacylglycerol O-acyltransferase 2	0.016
ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3	0.016
FMO5	flavin containing monooxygenase 5	0.016
SGK2	serum/glucocorticoid regulated kinase 2	0.016
UGT2B28	UDP glucuronosyltransferase 2 family, polypeptide B28	0.015
CEACAM5	carcinoembryonic antigen-related cell adhesion molecule 5	0.015
PRLR	prolactin receptor	0.015
SLCO1B3	solute carrier organic anion transporter family, member 1B3	0.015
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.015
OR2B6	olfactory receptor, family 2, subfamily B, member 6	0.015
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.015
HSD17B3	hydroxysteroid (17-beta) dehydrogenase 3	0.015
PLA2G10	phospholipase A2, group X	0.015
PIP	prolactin-induced protein	0.015
LIPF	lipase, gastric	0.015
F5	coagulation factor V (proaccelerin, labile factor)	0.015
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.015
LGALS4	lectin, galactoside-binding, soluble, 4	0.015
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.015
CRISP2	cysteine-rich secretory protein 2	0.015
F12	coagulation factor XII (Hageman factor)	0.015
CHAD	chondroadherin	0.015
LIPC	lipase, hepatic	0.014
ANXA13	annexin A13	0.014
AOC2	amine oxidase, copper containing 2 (retina-specific)	0.014
CADM4	cell adhesion molecule 4	0.014
AGXT	alanine-glyoxylate aminotransferase	0.014
ZG16	zymogen granule protein 16 homolog (rat)	0.014
AHSG	alpha-2-HS-glycoprotein	0.014
HNF4G	hepatocyte nuclear factor 4, gamma	0.014
REG1A	regenerating islet-derived 1 alpha	0.014
CD4	CD4 molecule	0.014
GNMT	glycine N-methyltransferase	0.014
AGXT2L1	alanine-glyoxylate aminotransferase 2-like 1	0.014
NAT8	N-acetyltransferase 8 (GCN5-related, putative)	0.013
VTCN1	V-set domain containing T cell activation inhibitor 1	0.013
TRIM15	tripartite motif containing 15	0.013
SPINT3	serine peptidase inhibitor, Kunitz type, 3	0.013
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.013
SAA4	serum amyloid A4, constitutive	0.013
HAAO	3-hydroxyanthranilate 3,4-dioxygenase	0.013
A2M	alpha-2-macroglobulin	0.013
OVGP1	oviductal glycoprotein 1, 120kDa	0.013
SLC30A10	solute carrier family 30, member 10	0.013
B3GNT3	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3	0.013
STAB2	stabilin 2	0.013
GSTT1	glutathione S-transferase theta 1	0.013
KHK	ketohexokinase (fructokinase)	0.012
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.012
APOA2	apolipoprotein A-II	0.012
GPR110	G protein-coupled receptor 110	0.012
HGFAC	HGF activator	0.012
ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.012
PRODH	proline dehydrogenase (oxidase) 1	0.012
UPB1	ureidopropionase, beta	0.012
CPS1	carbamoyl-phosphate synthase 1, mitochondrial	0.012
POF1B	premature ovarian failure, 1B	0.012
AQP7	aquaporin 7	0.012
S100A14	S100 calcium binding protein A14	0.012
GJB1	gap junction protein, beta 1, 32kDa	0.012
UGT1A7	UDP glucuronosyltransferase 1 family, polypeptide A7	0.012
FABP2	fatty acid binding protein 2, intestinal	0.012
SLC7A9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.012
NTS	neurotensin	0.012
FUT3	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)	0.012
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)	0.012
LRTOMT	leucine rich transmembrane and 0-methyltransferase domain containing	0.012
TEC	tec protein tyrosine kinase	0.012
APOB	apolipoprotein B (including Ag(x) antigen)	0.012
TTR	transthyretin	0.012
SPINK1	serine peptidase inhibitor, Kazal type 1	0.012
SULT1C2	sulfotransferase family, cytosolic, 1C, member 2	0.012
CRISP3	cysteine-rich secretory protein 3	0.012
FMO3	flavin containing monooxygenase 3	0.012
PLIN1	perilipin 1	0.011
LRRC19	leucine rich repeat containing 19	0.011
ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.011
HHLA2	HERV-H LTR-associating 2	0.011
HSD3B2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.011
UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.011
SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4	0.011
TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)	0.011
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.011
SLC38A3	solute carrier family 38, member 3	0.011
C5	complement component 5	0.011
HP	haptoglobin	0.011
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.011
APOBEC1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.011
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.011
UPK1B	uroplakin 1B	0.011
ABCA5	ATP-binding cassette, sub-family A (ABC1), member 5	0.011
ACADL	acyl-CoA dehydrogenase, long chain	0.011
UGT2B4	UDP glucuronosyltransferase 2 family, polypeptide B4	0.011
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.011
RORC	RAR-related orphan receptor C	0.011
CCDC30	coiled-coil domain containing 30	0.011
MEP1A	meprin A, alpha (PABA peptide hydrolase)	0.010
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.010
SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.010
SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.010
ZNF132	zinc finger protein 132	0.010
SLC38A4	solute carrier family 38, member 4	0.010
PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.010
C1orf116	chromosome 1 open reading frame 116	0.010
ZKSCAN3	zinc finger with KRAB and SCAN domains 3	0.010
GPR128	G protein-coupled receptor 128	0.010
SPP2	secreted phosphoprotein 2, 24kDa	0.010
GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	0.010
ADAM20	ADAM metallopeptidase domain 20	0.010
CES1	carboxylesterase 1	0.010
TTC22	tetratricopeptide repeat domain 22	0.010
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.010
TAS2R3	taste receptor, type 2, member 3	0.010
BCMO1	beta-carotene 15,15'-monooxygenase 1	0.010