IMP
Process View
interleukin 4 mediated signaling pathway
A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "interleukin 4 mediated signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.994 | Human | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.977 | Human | |
| JAK2 | Janus kinase 2 | 0.973 | Human | |
| JAK1 | Janus kinase 1 | 0.867 | Human | |
| GHR | growth hormone receptor | 0.760 | ||
| IRF9 | interferon regulatory factor 9 | 0.727 | ||
| STAT5A | signal transducer and activator of transcription 5A | 0.641 | Human | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.632 | ||
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.612 | ||
| IL4R | interleukin 4 receptor | 0.607 | ||
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.351 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.187 | ||
| IFNGR1 | interferon gamma receptor 1 | 0.163 | ||
| CAPN1 | calpain 1, (mu/I) large subunit | 0.153 | ||
| INSR | insulin receptor | 0.145 | ||
| NMI | N-myc (and STAT) interactor | 0.103 | ||
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.098 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.088 | ||
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.083 | Human | |
| SOCS3 | suppressor of cytokine signaling 3 | 0.074 | ||
| STAT5B | signal transducer and activator of transcription 5B | 0.063 | Human | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.054 | ||
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.049 | ||
| EPOR | erythropoietin receptor | 0.046 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.034 | ||
| EGFR | epidermal growth factor receptor | 0.033 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.026 | ||
| IL2RB | interleukin 2 receptor, beta | 0.026 | ||
| IL12RB2 | interleukin 12 receptor, beta 2 | 0.023 | ||
| SH2B1 | SH2B adaptor protein 1 | 0.021 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.021 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.018 | Human | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.018 | ||
| LAT | linker for activation of T cells | 0.015 | ||
| STAP2 | signal transducing adaptor family member 2 | 0.015 | ||
| CTTN | cortactin | 0.014 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.014 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.013 | ||
| MAVS | mitochondrial antiviral signaling protein | 0.012 | ||
| IRS1 | insulin receptor substrate 1 | 0.011 | ||
| TYK2 | tyrosine kinase 2 | 0.011 | Human | |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.010 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.010 | ||
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.010 |