IMP

Process View

Homo sapiens

3 genes annotated in human

positive regulation of vascular endothelial growth factor signaling pathway

GO:1900748

Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of vascular endothelial growth factor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of vascular endothelial growth factor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
PCYT2	phosphate cytidylyltransferase 2, ethanolamine	0.999
GIPC1	GIPC PDZ domain containing family, member 1	0.730
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.437
RIPK3	receptor-interacting serine-threonine kinase 3	0.356
HMGCL	3-hydroxymethyl-3-methylglutaryl-CoA lyase	0.261
DNM2	dynamin 2	0.206
CTTN	cortactin	0.171
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.149
TFRC	transferrin receptor (p90, CD71)	0.141
NEK6	NIMA (never in mitosis gene a)-related kinase 6	0.125
COMP	cartilage oligomeric matrix protein	0.118
PHLDA3	pleckstrin homology-like domain, family A, member 3	0.101
TRAF7	TNF receptor-associated factor 7	0.092
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.081
TYK2	tyrosine kinase 2	0.074
COL13A1	collagen, type XIII, alpha 1	0.062
MAP2K5	mitogen-activated protein kinase kinase 5	0.050
HMGXB3	HMG box domain containing 3	0.044
UBASH3B	ubiquitin associated and SH3 domain containing B	0.043
EHD2	EH-domain containing 2	0.043
PTPRG	protein tyrosine phosphatase, receptor type, G	0.042
SH3BP4	SH3-domain binding protein 4	0.042
PRMT2	protein arginine methyltransferase 2	0.041
WISP1	WNT1 inducible signaling pathway protein 1	0.038
MTA2	metastasis associated 1 family, member 2	0.038
EMILIN2	elastin microfibril interfacer 2	0.036
TPBG	trophoblast glycoprotein	0.035
BMP1	bone morphogenetic protein 1	0.031
ESR2	estrogen receptor 2 (ER beta)	0.029
SNX9	sorting nexin 9	0.028
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.028
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.028
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.028
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.028
HOXD8	homeobox D8	0.025
AKAP13	A kinase (PRKA) anchor protein 13	0.024
CD248	CD248 molecule, endosialin	0.023
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.022
ACAN	aggrecan	0.022
PELO	pelota homolog (Drosophila)	0.021
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.020
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.020
GPR124	G protein-coupled receptor 124	0.020
GLI2	GLI family zinc finger 2	0.020
COL11A1	collagen, type XI, alpha 1	0.020
TMSB4X	thymosin beta 4, X-linked	0.019
ADAMTSL4	ADAMTS-like 4	0.019
SLC26A10	solute carrier family 26, member 10	0.018
CRIP2	cysteine-rich protein 2	0.018
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.018
ITSN1	intersectin 1 (SH3 domain protein)	0.018
ACTG1	actin, gamma 1	0.017
ALAS1	aminolevulinate, delta-, synthase 1	0.017
GPR153	G protein-coupled receptor 153	0.017
CREB3L1	cAMP responsive element binding protein 3-like 1	0.017
ZNF366	zinc finger protein 366	0.017
MYO1C	myosin IC	0.017
ITGA11	integrin, alpha 11	0.016
FBXO25	F-box protein 25	0.016
CSF1	colony stimulating factor 1 (macrophage)	0.016
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.015
GPR68	G protein-coupled receptor 68	0.015
RAB3IL1	RAB3A interacting protein (rabin3)-like 1	0.015
BNC2	basonuclin 2	0.015
CCDC40	coiled-coil domain containing 40	0.015
CLMP	CXADR-like membrane protein	0.014
SYNJ1	synaptojanin 1	0.014
CHRNG	cholinergic receptor, nicotinic, gamma	0.014
ANGPT2	angiopoietin 2	0.014
LIMS2	LIM and senescent cell antigen-like domains 2	0.014
DMWD	dystrophia myotonica, WD repeat containing	0.014
GDPD4	glycerophosphodiester phosphodiesterase domain containing 4	0.014
UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	0.014
USP20	ubiquitin specific peptidase 20	0.014
ALS2CL	ALS2 C-terminal like	0.014
COL8A2	collagen, type VIII, alpha 2	0.013
ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	0.013	Human
A2M	alpha-2-macroglobulin	0.013
ZBP1	Z-DNA binding protein 1	0.013
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.013
CD80	CD80 molecule	0.013
CST4	cystatin S	0.013
ADAMTS13	ADAM metallopeptidase with thrombospondin type 1 motif, 13	0.013	Human
APCDD1L	adenomatosis polyposis coli down-regulated 1-like	0.013
FURIN	furin (paired basic amino acid cleaving enzyme)	0.013
NKD2	naked cuticle homolog 2 (Drosophila)	0.012
PRND	prion protein 2 (dublet)	0.012
A1BG	alpha-1-B glycoprotein	0.012
PNPLA2	patatin-like phospholipase domain containing 2	0.012
FOXS1	forkhead box S1	0.012
MARK2	MAP/microtubule affinity-regulating kinase 2	0.012
LRRK2	leucine-rich repeat kinase 2	0.012
MYO1B	myosin IB	0.012	Human
HES2	hairy and enhancer of split 2 (Drosophila)	0.012
HOXB5	homeobox B5	0.012
TBXA2R	thromboxane A2 receptor	0.012
SCARF2	scavenger receptor class F, member 2	0.012
ZBTB16	zinc finger and BTB domain containing 16	0.012
NEK9	NIMA (never in mitosis gene a)- related kinase 9	0.012
TSPAN9	tetraspanin 9	0.012
VASN	vasorin	0.012
MXRA8	matrix-remodelling associated 8	0.012
PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.012
C10orf72	chromosome 10 open reading frame 72	0.012
PRRX2	paired related homeobox 2	0.011
C1QTNF1	C1q and tumor necrosis factor related protein 1	0.011
PLD2	phospholipase D2	0.011
DEFB4A	defensin, beta 4A	0.011
RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)	0.011
INPP5K	inositol polyphosphate-5-phosphatase K	0.011
KIF1C	kinesin family member 1C	0.011
SLC17A9	solute carrier family 17, member 9	0.011
CDR2L	cerebellar degeneration-related protein 2-like	0.011
HOXC5	homeobox C5	0.011
ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.011
SLC16A8	solute carrier family 16, member 8 (monocarboxylic acid transporter 3)	0.011
CLCF1	cardiotrophin-like cytokine factor 1	0.011
ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma	0.011
OXTR	oxytocin receptor	0.011
FAM167B	family with sequence similarity 167, member B	0.011
EVC	Ellis van Creveld syndrome	0.011
CLEC4F	C-type lectin domain family 4, member F	0.011
GAB2	GRB2-associated binding protein 2	0.011
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.011
TUBA1A	tubulin, alpha 1a	0.011
STAC	SH3 and cysteine rich domain	0.011
PXDN	peroxidasin homolog (Drosophila)	0.011
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.011
CLSTN3	calsyntenin 3	0.010
CNTNAP1	contactin associated protein 1	0.010
LRRC15	leucine rich repeat containing 15	0.010
DDR2	discoidin domain receptor tyrosine kinase 2	0.010
CARD11	caspase recruitment domain family, member 11	0.010
POU4F2	POU class 4 homeobox 2	0.010
ZNF469	zinc finger protein 469	0.010
ECM1	extracellular matrix protein 1	0.010
MYO1D	myosin ID	0.010	Human
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.010
PTPRH	protein tyrosine phosphatase, receptor type, H	0.010
KIRREL	kin of IRRE like (Drosophila)	0.010
NOTUM	notum pectinacetylesterase homolog (Drosophila)	0.010
DPEP1	dipeptidase 1 (renal)	0.010
GRIP1	glutamate receptor interacting protein 1	0.010
LRRC32	leucine rich repeat containing 32	0.010
PODNL1	podocan-like 1	0.010
HAND1	heart and neural crest derivatives expressed 1	0.010
SIAH2	seven in absentia homolog 2 (Drosophila)	0.010
ZNF536	zinc finger protein 536	0.010
KLHL25	kelch-like 25 (Drosophila)	0.010