IMP
Process View
cd4 positive alpha beta t cell activation
The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
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Click on a gene's description to view its network relationships with genes known to be involved in "cd4 positive alpha beta t cell activation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| IL4R | interleukin 4 receptor | 0.903 | Mouse | |
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.568 | ||
| IL8 | interleukin 8 | 0.310 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.285 | ||
| CCR5 | chemokine (C-C motif) receptor 5 | 0.241 | ||
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.201 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.140 | Human | |
| LIN9 | lin-9 homolog (C. elegans) | 0.121 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.119 | ||
| ICAM1 | intercellular adhesion molecule 1 | 0.114 | ||
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.103 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.096 | Mouse | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.077 | Human | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.077 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.067 | ||
| CCL22 | chemokine (C-C motif) ligand 22 | 0.057 | Human | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.050 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.047 | Human | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.047 | ||
| CCL2 | chemokine (C-C motif) ligand 2 | 0.046 | Human | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.042 | ||
| MEOX1 | mesenchyme homeobox 1 | 0.042 | ||
| RARA | retinoic acid receptor, alpha | 0.041 | ||
| PPARA | peroxisome proliferator-activated receptor alpha | 0.038 | ||
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.033 | ||
| IL4 | interleukin 4 | 0.033 | Mouse | |
| IL1B | interleukin 1, beta | 0.032 | ||
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.030 | Human | |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 | 0.029 | ||
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.027 | ||
| IL23A | interleukin 23, alpha subunit p19 | 0.027 | Mouse | |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.027 | Mouse | |
| NLK | nemo-like kinase | 0.025 | ||
| RXRA | retinoid X receptor, alpha | 0.024 | ||
| DPP4 | dipeptidyl-peptidase 4 | 0.024 | ||
| PDZD11 | PDZ domain containing 11 | 0.023 | ||
| IL7R | interleukin 7 receptor | 0.022 | ||
| SOCS3 | suppressor of cytokine signaling 3 | 0.022 | ||
| CCL13 | chemokine (C-C motif) ligand 13 | 0.019 | Human | |
| NCOA1 | nuclear receptor coactivator 1 | 0.018 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.017 | Mouse | |
| BCL3 | B-cell CLL/lymphoma 3 | 0.016 | Mouse | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.015 | Human Mouse | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.013 | ||
| HDAC9 | histone deacetylase 9 | 0.013 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.012 | ||
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.011 | ||
| IFNG | interferon, gamma | 0.010 | ||
| IL2RB | interleukin 2 receptor, beta | 0.010 |