IMP

Process View

Homo sapiens

22 genes annotated in human

Multi-species View

regulation of megakaryocyte differentiation

GO:0045652

Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of megakaryocyte differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of megakaryocyte differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
HIST1H2AJ	histone cluster 1, H2aj	0.996	Human
HIST1H3B	histone cluster 1, H3b	0.975
HIST1H2AM	histone cluster 1, H2am	0.972
HIST1H2BG	histone cluster 1, H2bg	0.958
HIST1H4B	histone cluster 1, H4b	0.949
HIST1H2AL	histone cluster 1, H2al	0.890	Human
HDAC3	histone deacetylase 3	0.870
HIST1H3A	histone cluster 1, H3a	0.833
CXCL2	chemokine (C-X-C motif) ligand 2	0.818
HIST1H4D	histone cluster 1, H4d	0.793
HIST1H2BJ	histone cluster 1, H2bj	0.695
HIST1H4H	histone cluster 1, H4h	0.686
TAL1	T-cell acute lymphocytic leukemia 1	0.644
HIST1H2AI	histone cluster 1, H2ai	0.601	Human
HIST1H4A	histone cluster 1, H4a	0.600
HIST1H2AB	histone cluster 1, H2ab	0.591	Human
HIST1H1E	histone cluster 1, H1e	0.581
HIST1H1C	histone cluster 1, H1c	0.555
HMGB1	high mobility group box 1	0.506	Human
SP1	Sp1 transcription factor	0.495
PTMA	prothymosin, alpha	0.428
PSEN2	presenilin 2 (Alzheimer disease 4)	0.411
HIST1H4C	histone cluster 1, H4c	0.405
CXCL11	chemokine (C-X-C motif) ligand 11	0.379	Human
CXCL5	chemokine (C-X-C motif) ligand 5	0.335	Human
SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.334
HIST1H2BM	histone cluster 1, H2bm	0.322
KDM1A	lysine (K)-specific demethylase 1A	0.313	Mouse
HIST1H4E	histone cluster 1, H4e	0.295
PRMT1	protein arginine methyltransferase 1	0.274
HIST1H2AE	histone cluster 1, H2ae	0.256	Human
SP3	Sp3 transcription factor	0.242
HIST1H2BB	histone cluster 1, H2bb	0.233
HIST1H4L	histone cluster 1, H4l	0.218
HMGA1	high mobility group AT-hook 1	0.195
HIST1H2AG	histone cluster 1, H2ag	0.194	Human
HIST1H2BN	histone cluster 1, H2bn	0.180
HIST1H3G	histone cluster 1, H3g	0.179
HIST1H4F	histone cluster 1, H4f	0.177
HMG20A	high mobility group 20A	0.175
NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.164
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.164	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.158	Human
HMGB2	high mobility group box 2	0.145
CSNK1A1	casein kinase 1, alpha 1	0.144
WASL	Wiskott-Aldrich syndrome-like	0.138
HIST1H2BD	histone cluster 1, H2bd	0.138
HIST1H4I	histone cluster 1, H4i	0.128
HIST2H4B	histone cluster 2, H4b	0.120
HIST2H2BE	histone cluster 2, H2be	0.116
HIST1H4J	histone cluster 1, H4j	0.108
HIST1H2AK	histone cluster 1, H2ak	0.107	Human
PHF10	PHD finger protein 10	0.105
HIST1H2BO	histone cluster 1, H2bo	0.103
HIST1H2BI	histone cluster 1, H2bi	0.091
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.077
DPP4	dipeptidyl-peptidase 4	0.077
CXCL10	chemokine (C-X-C motif) ligand 10	0.073	Human
HMGN2	high mobility group nucleosomal binding domain 2	0.067
HIST1H3C	histone cluster 1, H3c	0.065
HDAC4	histone deacetylase 4	0.064
HIST1H3F	histone cluster 1, H3f	0.064
HIST1H3I	histone cluster 1, H3i	0.057
HIST1H3D	histone cluster 1, H3d	0.052	Human
HIST1H2AH	histone cluster 1, H2ah	0.049	Human
ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B	0.048
DUT	deoxyuridine triphosphatase	0.046
UBD	ubiquitin D	0.046
CCL8	chemokine (C-C motif) ligand 8	0.043
HIST1H1D	histone cluster 1, H1d	0.042
HIST1H2BL	histone cluster 1, H2bl	0.036
HIST1H2BC	histone cluster 1, H2bc	0.035
HIST2H2AA4	histone cluster 2, H2aa4	0.031	Human
HIST1H3E	histone cluster 1, H3e	0.031
HIST2H4A	histone cluster 2, H4a	0.030
HIST1H3H	histone cluster 1, H3h	0.030
HIST1H3J	histone cluster 1, H3j	0.030
ILF3	interleukin enhancer binding factor 3, 90kDa	0.030
CXCL3	chemokine (C-X-C motif) ligand 3	0.028	Human
TP53BP1	tumor protein p53 binding protein 1	0.027
HDAC2	histone deacetylase 2	0.027
SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.027
POU2F1	POU class 2 homeobox 1	0.026
PF4V1	platelet factor 4 variant 1	0.025	Human
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.024
CCL20	chemokine (C-C motif) ligand 20	0.022
RAI1	retinoic acid induced 1	0.022
OFCC1	orofacial cleft 1 candidate 1	0.022
RBM8A	RNA binding motif protein 8A	0.021
PF4	platelet factor 4	0.019
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.019
YY1	YY1 transcription factor	0.019
IDO1	indoleamine 2,3-dioxygenase 1	0.019
HIST3H3	histone cluster 3, H3	0.019
TEX11	testis expressed 11	0.018
HIST1H1B	histone cluster 1, H1b	0.018
KIAA0101	KIAA0101	0.018
MAGEA2	melanoma antigen family A, 2	0.018
CXCL13	chemokine (C-X-C motif) ligand 13	0.016
HIST2H2AA3	histone cluster 2, H2aa3	0.016	Human
STMN1	stathmin 1	0.016
BRD7	bromodomain containing 7	0.015
VCAM1	vascular cell adhesion molecule 1	0.015
CENPM	centromere protein M	0.015
HIST3H2A	histone cluster 3, H2a	0.015	Human
RREB1	ras responsive element binding protein 1	0.015
FAM9A	family with sequence similarity 9, member A	0.015
HIST1H2AC	histone cluster 1, H2ac	0.013	Human
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.013
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.012
EWSR1	Ewing sarcoma breakpoint region 1	0.012
HMGN1	high mobility group nucleosome binding domain 1	0.012
S100A12	S100 calcium binding protein A12	0.012
HIST4H4	histone cluster 4, H4	0.012
CXCR3	chemokine (C-X-C motif) receptor 3	0.012
SAP30	Sin3A-associated protein, 30kDa	0.011
CTCFL	CCCTC-binding factor (zinc finger protein)-like	0.011
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.011
MOBKL2B	MOB1, Mps One Binder kinase activator-like 2B (yeast)	0.011
RNF168	ring finger protein 168	0.011
PI3	peptidase inhibitor 3, skin-derived	0.011
ZNF320	zinc finger protein 320	0.010
CCNB2	cyclin B2	0.010