IMP
Process View
t helper 2 cell differentiation
The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "t helper 2 cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NCOR2 | nuclear receptor corepressor 2 | 0.970 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.887 | ||
| RARA | retinoic acid receptor, alpha | 0.796 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.758 | ||
| RXRA | retinoid X receptor, alpha | 0.721 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.679 | ||
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.584 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.536 | ||
| PPARA | peroxisome proliferator-activated receptor alpha | 0.494 | ||
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.435 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.299 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.120 | ||
| IL6R | interleukin 6 receptor | 0.120 | ||
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.116 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.073 | ||
| HDAC3 | histone deacetylase 3 | 0.062 | ||
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 | 0.061 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.058 | ||
| PGR | progesterone receptor | 0.057 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.056 | ||
| FOSL2 | FOS-like antigen 2 | 0.052 | ||
| HDAC5 | histone deacetylase 5 | 0.050 | ||
| CREBBP | CREB binding protein | 0.045 | ||
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 0.044 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.044 | ||
| KLHL24 | kelch-like 24 (Drosophila) | 0.044 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.041 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.040 | ||
| SLC25A36 | solute carrier family 25, member 36 | 0.038 | ||
| ZNF71 | zinc finger protein 71 | 0.037 | ||
| MED25 | mediator complex subunit 25 | 0.036 | ||
| CCDC115 | coiled-coil domain containing 115 | 0.035 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.032 | ||
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.029 | ||
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.027 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.027 | ||
| HDAC9 | histone deacetylase 9 | 0.026 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.026 | ||
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.024 | ||
| CD247 | CD247 molecule | 0.023 | ||
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | 0.022 | ||
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.022 | ||
| C5orf41 | chromosome 5 open reading frame 41 | 0.021 | ||
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.021 | ||
| SPIN1 | spindlin 1 | 0.019 | ||
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.018 | ||
| NMT2 | N-myristoyltransferase 2 | 0.017 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.017 | ||
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.016 | ||
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.016 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.016 | ||
| ATXN1L | ataxin 1-like | 0.015 | ||
| MED1 | mediator complex subunit 1 | 0.014 | ||
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 0.014 | ||
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.014 | ||
| FOSL1 | FOS-like antigen 1 | 0.013 | ||
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.013 | ||
| SAP30 | Sin3A-associated protein, 30kDa | 0.013 | ||
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.013 | ||
| NINJ1 | ninjurin 1 | 0.013 | ||
| PRKD2 | protein kinase D2 | 0.013 | ||
| HDAC4 | histone deacetylase 4 | 0.013 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.012 | ||
| POU2F3 | POU class 2 homeobox 3 | 0.012 | ||
| PPARG | peroxisome proliferator-activated receptor gamma | 0.012 | ||
| BCL10 | B-cell CLL/lymphoma 10 | 0.012 | ||
| ESR1 | estrogen receptor 1 | 0.012 | ||
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.012 | ||
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 | 0.011 | ||
| THRA | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 0.011 | Human | |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.010 | ||
| HDAC7 | histone deacetylase 7 | 0.010 | ||
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.010 | ||
| HRH1 | histamine receptor H1 | 0.010 | ||
| EBF1 | early B-cell factor 1 | 0.010 | ||
| IL21R | interleukin 21 receptor | 0.010 |