IMP

Process View

Homo sapiens

2 genes annotated in human

positive regulation of t cell receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of t cell receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of t cell receptor signaling pathway" (in gray)

Name	Description	Probability
HDAC7	histone deacetylase 7	0.982
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.898
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.561
LCK	lymphocyte-specific protein tyrosine kinase	0.406
GORASP1	golgi reassembly stacking protein 1, 65kDa	0.207
PDLIM7	PDZ and LIM domain 7 (enigma)	0.162
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.116
CD247	CD247 molecule	0.086
MED25	mediator complex subunit 25	0.077
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.076
RXRA	retinoid X receptor, alpha	0.055
CD2	CD2 molecule	0.052
SH2D1A	SH2 domain containing 1A	0.048
ITK	IL2-inducible T-cell kinase	0.038
FAIM3	Fas apoptotic inhibitory molecule 3	0.027
GPR18	G protein-coupled receptor 18	0.022
STAT4	signal transducer and activator of transcription 4	0.020
RHBDF2	rhomboid 5 homolog 2 (Drosophila)	0.019
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.016
IL2RB	interleukin 2 receptor, beta	0.016
SFN	stratifin	0.016
IL7R	interleukin 7 receptor	0.015
CLK2	CDC-like kinase 2	0.015
IL21R	interleukin 21 receptor	0.013
CD3D	CD3d molecule, delta (CD3-TCR complex)	0.013
CD27	CD27 molecule	0.012
APBA3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.012
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.012
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.011
GPR183	G protein-coupled receptor 183	0.010
PRKCQ	protein kinase C, theta	0.010
PRF1	perforin 1 (pore forming protein)	0.010
ACTN4	actinin, alpha 4	0.010
IL2RG	interleukin 2 receptor, gamma	0.010