IMP
Process View
muscle hypertrophy
The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "muscle hypertrophy"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.772 | ||
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha | 0.362 | Human | |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.354 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.229 | ||
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | 0.174 | ||
| VPS29 | vacuolar protein sorting 29 homolog (S. cerevisiae) | 0.166 | ||
| ITGB1BP3 | integrin beta 1 binding protein 3 | 0.149 | ||
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.138 | ||
| ZYX | zyxin | 0.131 | ||
| NEB | nebulin | 0.131 | ||
| TRIM63 | tripartite motif containing 63 | 0.109 | ||
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta | 0.106 | Human | |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.092 | ||
| C3orf15 | chromosome 3 open reading frame 15 | 0.079 | ||
| HDAC4 | histone deacetylase 4 | 0.077 | ||
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 | 0.060 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.058 | ||
| CAPN3 | calpain 3, (p94) | 0.054 | ||
| MAPK8 | mitogen-activated protein kinase 8 | 0.053 | ||
| MAPK14 | mitogen-activated protein kinase 14 | 0.053 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.049 | ||
| MAPK9 | mitogen-activated protein kinase 9 | 0.045 | ||
| TCAP | titin-cap (telethonin) | 0.045 | ||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.044 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.037 | ||
| MYOZ2 | myozenin 2 | 0.034 | ||
| IGF2R | insulin-like growth factor 2 receptor | 0.032 | ||
| TTN | titin | 0.032 | ||
| DLG2 | discs, large homolog 2 (Drosophila) | 0.032 | ||
| CALCA | calcitonin-related polypeptide alpha | 0.031 | ||
| MYCBP | c-myc binding protein | 0.027 | ||
| MYOZ1 | myozenin 1 | 0.026 | ||
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.026 | ||
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.025 | ||
| PRKCQ | protein kinase C, theta | 0.025 | ||
| MAPK6 | mitogen-activated protein kinase 6 | 0.023 | ||
| KLF13 | Kruppel-like factor 13 | 0.023 | ||
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.023 | ||
| CYLD | cylindromatosis (turban tumor syndrome) | 0.021 | ||
| AKAP6 | A kinase (PRKA) anchor protein 6 | 0.021 | ||
| OSGEP | O-sialoglycoprotein endopeptidase | 0.021 | ||
| DES | desmin | 0.020 | ||
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.020 | ||
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.019 | ||
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.019 | ||
| HDAC9 | histone deacetylase 9 | 0.018 | ||
| ACTN1 | actinin, alpha 1 | 0.018 | ||
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | 0.018 | ||
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.017 | ||
| NOG | noggin | 0.016 | ||
| MYOD1 | myogenic differentiation 1 | 0.016 | ||
| HIST1H4F | histone cluster 1, H4f | 0.016 | ||
| MBNL1 | muscleblind-like (Drosophila) | 0.015 | ||
| HSPB8 | heat shock 22kDa protein 8 | 0.015 | ||
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.014 | Human | |
| OBSL1 | obscurin-like 1 | 0.014 | ||
| PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.014 | ||
| HIST1H3B | histone cluster 1, H3b | 0.013 | ||
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | 0.013 | ||
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) | 0.012 | ||
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | 0.012 | ||
| DCN | decorin | 0.012 | ||
| HSPB2 | heat shock 27kDa protein 2 | 0.011 | ||
| CRYBB2 | crystallin, beta B2 | 0.011 | ||
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.011 | ||
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.010 | ||
| FRZB | frizzled-related protein | 0.010 | ||
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.010 |