IMP
Process View
gpi anchor metabolic process
The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
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Click on a gene's description to view its network relationships with genes known to be involved in "gpi anchor metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Immp1l | IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.538 | ||
| 5730494N06Rik | RIKEN cDNA 5730494N06 gene | 0.488 | ||
| 1110058L19Rik | RIKEN cDNA 1110058L19 gene | 0.126 | ||
| Atp5s | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s | 0.118 | ||
| Pvalb | parvalbumin | 0.100 | ||
| Srp14 | signal recognition particle 14 | 0.094 | ||
| 1810030N24Rik | RIKEN cDNA 1810030N24 gene | 0.081 | ||
| Acyp1 | acylphosphatase 1, erythrocyte (common) type | 0.070 | ||
| Cstf2 | cleavage stimulation factor, 3' pre-RNA subunit 2 | 0.064 | ||
| Eef1a2 | eukaryotic translation elongation factor 1 alpha 2 | 0.060 | ||
| Fam103a1 | family with sequence similarity 103, member A1 | 0.055 | ||
| Tmem218 | transmembrane protein 218 | 0.054 | ||
| 1500031L02Rik | RIKEN cDNA 1500031L02 gene | 0.052 | ||
| Rnf7 | ring finger protein 7 | 0.050 | ||
| Fnta | farnesyltransferase, CAAX box, alpha | 0.045 | ||
| Pex7 | peroxisomal biogenesis factor 7 | 0.044 | ||
| Pigo | phosphatidylinositol glycan anchor biosynthesis, class O | 0.043 | ||
| Anln | anillin, actin binding protein | 0.039 | ||
| Tmem128 | transmembrane protein 128 | 0.037 | ||
| Isca1 | iron-sulfur cluster assembly 1 homolog (S. cerevisiae) | 0.037 | ||
| Paip2 | polyadenylate-binding protein-interacting protein 2 | 0.036 | ||
| 0610007C21Rik | RIKEN cDNA 0610007C21 gene | 0.034 | ||
| Cox6a2 | cytochrome c oxidase, subunit VI a, polypeptide 2 | 0.034 | ||
| 2310044H10Rik | RIKEN cDNA 2310044H10 gene | 0.033 | ||
| Ints1 | integrator complex subunit 1 | 0.033 | ||
| Pigf | phosphatidylinositol glycan anchor biosynthesis, class F | 0.033 | ||
| Polr3k | polymerase (RNA) III (DNA directed) polypeptide K | 0.033 | ||
| Lyrm2 | LYR motif containing 2 | 0.032 | ||
| H47 | histocompatibility 47 | 0.032 | ||
| Tuba8 | tubulin, alpha 8 | 0.031 | ||
| Wdr20a | WD repeat domain 20A | 0.031 | ||
| Atad3a | ATPase family, AAA domain containing 3A | 0.029 | ||
| Pygm | muscle glycogen phosphorylase | 0.028 | ||
| Arl3 | ADP-ribosylation factor-like 3 | 0.028 | ||
| Zmiz2 | zinc finger, MIZ-type containing 2 | 0.028 | ||
| Polr2k | polymerase (RNA) II (DNA directed) polypeptide K | 0.027 | ||
| Tprgl | transformation related protein 63 regulated like | 0.027 | ||
| 2410022L05Rik | RIKEN cDNA 2410022L05 gene | 0.027 | ||
| Tcap | titin-cap | 0.025 | ||
| Hps4 | Hermansky-Pudlak syndrome 4 homolog (human) | 0.023 | ||
| 1110005A03Rik | RIKEN cDNA 1110005A03 gene | 0.023 | ||
| Caml | calcium modulating ligand | 0.022 | ||
| 0610037P05Rik | RIKEN cDNA 0610037P05 gene | 0.022 | ||
| Atp2a1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 0.022 | ||
| Rnf123 | ring finger protein 123 | 0.021 | ||
| Brp44 | brain protein 44 | 0.021 | ||
| Med31 | mediator of RNA polymerase II transcription, subunit 31 homolog (yeast) | 0.021 | ||
| Pdcd2 | programmed cell death 2 | 0.021 | ||
| Actr6 | ARP6 actin-related protein 6 homolog (yeast) | 0.020 | ||
| March6 | membrane-associated ring finger (C3HC4) 6 | 0.020 | ||
| Bnip3 | BCL2/adenovirus E1B interacting protein 3 | 0.020 | ||
| 2700097O09Rik | RIKEN cDNA 2700097O09 gene | 0.020 | ||
| Srp19 | signal recognition particle 19 | 0.019 | ||
| Ube2t | ubiquitin-conjugating enzyme E2T (putative) | 0.019 | ||
| Fitm1 | fat storage-inducing transmembrane protein 1 | 0.019 | ||
| Tomm7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | 0.018 | ||
| 1110059E24Rik | RIKEN cDNA 1110059E24 gene | 0.018 | ||
| Gstm5 | glutathione S-transferase, mu 5 | 0.018 | ||
| Pfn2 | profilin 2 | 0.017 | ||
| Haus3 | HAUS augmin-like complex, subunit 3 | 0.017 | ||
| Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.017 | ||
| Ube2g1 | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans) | 0.016 | ||
| Creld2 | cysteine-rich with EGF-like domains 2 | 0.016 | ||
| Sdf2 | stromal cell derived factor 2 | 0.016 | ||
| Uchl5 | ubiquitin carboxyl-terminal esterase L5 | 0.016 | ||
| Tcta | T-cell leukemia translocation altered gene | 0.016 | ||
| Hsbp1 | heat shock factor binding protein 1 | 0.016 | ||
| Hiat1 | hippocampus abundant gene transcript 1 | 0.016 | ||
| Vti1b | vesicle transport through interaction with t-SNAREs 1B homolog | 0.015 | ||
| Man2c1 | mannosidase, alpha, class 2C, member 1 | 0.015 | ||
| Yipf5 | Yip1 domain family, member 5 | 0.015 | ||
| 1700025K23Rik | RIKEN cDNA 1700025K23 gene | 0.015 | ||
| Muted | muted | 0.015 | ||
| 1700029F09Rik | RIKEN cDNA 1700029F09 gene | 0.015 | ||
| BC023829 | cDNA sequence BC023829 | 0.015 | ||
| Rbm15 | RNA binding motif protein 15 | 0.015 | ||
| Tm2d2 | TM2 domain containing 2 | 0.014 | ||
| 2700060E02Rik | RIKEN cDNA 2700060E02 gene | 0.014 | ||
| Gemin6 | gem (nuclear organelle) associated protein 6 | 0.014 | ||
| Unc50 | unc-50 homolog (C. elegans) | 0.014 | ||
| Snip1 | Smad nuclear interacting protein 1 | 0.014 | ||
| Cript | cysteine-rich PDZ-binding protein | 0.014 | ||
| Spcs1 | signal peptidase complex subunit 1 homolog (S. cerevisiae) | 0.014 | ||
| Slc30a5 | solute carrier family 30 (zinc transporter), member 5 | 0.014 | ||
| 1110067D22Rik | RIKEN cDNA 1110067D22 gene | 0.014 | ||
| Ndfip1 | Nedd4 family interacting protein 1 | 0.013 | ||
| Slc25a14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.013 | ||
| Tab3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.013 | ||
| Asb11 | ankyrin repeat and SOCS box-containing 11 | 0.013 | ||
| Tbc1d19 | TBC1 domain family, member 19 | 0.013 | ||
| Krt10 | keratin 10 | 0.013 | ||
| Nup35 | nucleoporin 35 | 0.013 | ||
| 2610002J02Rik | RIKEN cDNA 2610002J02 gene | 0.013 | ||
| Ptgds | prostaglandin D2 synthase (brain) | 0.013 | ||
| Rg9mtd3 | RNA (guanine-9-) methyltransferase domain containing 3 | 0.013 | ||
| Cpox | coproporphyrinogen oxidase | 0.013 | ||
| Pam16 | presequence translocase-asssociated motor 16 homolog (S. cerevisiae) | 0.013 | ||
| Snx14 | sorting nexin 14 | 0.012 | ||
| Tsg101 | tumor susceptibility gene 101 | 0.012 | ||
| Ap4s1 | adaptor-related protein complex AP-4, sigma 1 | 0.012 | ||
| S100b | S100 protein, beta polypeptide, neural | 0.012 | ||
| Dbp | D site albumin promoter binding protein | 0.012 | ||
| Nkiras1 | NFKB inhibitor interacting Ras-like protein 1 | 0.012 | ||
| Scn4b | sodium channel, type IV, beta | 0.012 | ||
| Ttc33 | tetratricopeptide repeat domain 33 | 0.012 | ||
| Pacsin3 | protein kinase C and casein kinase substrate in neurons 3 | 0.012 | ||
| Ero1l | ERO1-like (S. cerevisiae) | 0.012 | ||
| 1110003E01Rik | RIKEN cDNA 1110003E01 gene | 0.012 | ||
| 3110009E18Rik | RIKEN cDNA 3110009E18 gene | 0.012 | ||
| Ift140 | intraflagellar transport 140 homolog (Chlamydomonas) | 0.012 | ||
| Atp6v1g1 | ATPase, H+ transporting, lysosomal V1 subunit G1 | 0.011 | ||
| Pfdn4 | prefoldin 4 | 0.011 | ||
| Pex3 | peroxisomal biogenesis factor 3 | 0.011 | ||
| Mterfd3 | MTERF domain containing 3 | 0.011 | ||
| 5730494M16Rik | RIKEN cDNA 5730494M16 gene | 0.011 | ||
| Acsl6 | acyl-CoA synthetase long-chain family member 6 | 0.011 | ||
| Snrnp27 | small nuclear ribonucleoprotein 27 (U4/U6.U5) | 0.011 | ||
| Donson | downstream neighbor of SON | 0.011 | ||
| Dsn1 | DSN1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.011 | ||
| Mettl5 | methyltransferase like 5 | 0.011 | ||
| Ptpn2 | protein tyrosine phosphatase, non-receptor type 2 | 0.011 | ||
| Rpn1 | ribophorin I | 0.011 | ||
| Amy1 | amylase 1, salivary | 0.011 | ||
| Plekhb1 | pleckstrin homology domain containing, family B (evectins) member 1 | 0.011 | ||
| Entpd4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.011 | ||
| Pgam2 | phosphoglycerate mutase 2 | 0.011 | ||
| BC017158 | cDNA sequence BC017158 | 0.011 | ||
| Wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.011 | ||
| Fam134b | family with sequence similarity 134, member B | 0.011 | ||
| Gyk | glycerol kinase | 0.011 | ||
| Ift20 | intraflagellar transport 20 homolog (Chlamydomonas) | 0.011 | ||
| Rars2 | arginyl-tRNA synthetase 2, mitochondrial | 0.010 | ||
| Sgca | sarcoglycan, alpha (dystrophin-associated glycoprotein) | 0.010 | ||
| 4933434E20Rik | RIKEN cDNA 4933434E20 gene | 0.010 | ||
| 1810020D17Rik | RIKEN cDNA 1810020D17 gene | 0.010 | ||
| Nenf | neuron derived neurotrophic factor | 0.010 | ||
| Hspa5 | heat shock protein 5 | 0.010 | ||
| Trappc10 | trafficking protein particle complex 10 | 0.010 |