Process View
The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "direct ossification"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Col1a1 | collagen, type I, alpha 1 | 0.739 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.322 | ||
| Col3a1 | collagen, type III, alpha 1 | 0.283 | Mouse | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.270 | ||
| Smo | smoothened homolog (Drosophila) | 0.252 | ||
| Fbn1 | fibrillin 1 | 0.241 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.166 | ||
| Col6a1 | collagen, type VI, alpha 1 | 0.111 | ||
| Col1a2 | collagen, type I, alpha 2 | 0.111 | Mouse | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.087 | ||
| Prrx1 | paired related homeobox 1 | 0.079 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 0.069 | ||
| Col5a2 | collagen, type V, alpha 2 | 0.065 | Mouse | |
| Msx1 | homeobox, msh-like 1 | 0.065 | ||
| Col6a2 | collagen, type VI, alpha 2 | 0.063 | ||
| Pthlh | parathyroid hormone-like peptide | 0.051 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.051 | ||
| Col5a1 | collagen, type V, alpha 1 | 0.039 | Mouse | |
| Runx2 | runt related transcription factor 2 | 0.032 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.029 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.029 | ||
| Col6a3 | collagen, type VI, alpha 3 | 0.028 | ||
| Sox9 | SRY-box containing gene 9 | 0.027 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.025 | ||
| Prrx2 | paired related homeobox 2 | 0.023 | ||
| Ltbp2 | latent transforming growth factor beta binding protein 2 | 0.021 | ||
| Tnc | tenascin C | 0.020 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.017 | ||
| Wisp1 | WNT1 inducible signaling pathway protein 1 | 0.017 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.016 | ||
| Clec4d | C-type lectin domain family 4, member d | 0.015 | ||
| Mfap5 | microfibrillar associated protein 5 | 0.014 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.014 | ||
| Mfap4 | microfibrillar-associated protein 4 | 0.014 | ||
| Col16a1 | collagen, type XVI, alpha 1 | 0.014 | ||
| Bgn | biglycan | 0.013 | ||
| Il6 | interleukin 6 | 0.012 | ||
| Loxl1 | lysyl oxidase-like 1 | 0.012 | ||
| Snai1 | snail homolog 1 (Drosophila) | 0.011 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.011 | ||
| Rnf111 | ring finger 111 | 0.011 | ||
| Fkbp10 | FK506 binding protein 10 | 0.010 | ||
| Creb3l1 | cAMP responsive element binding protein 3-like 1 | 0.010 |