Process View
The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "mature b cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.795 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.645 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.277 | ||
| Shh | sonic hedgehog | 0.213 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.144 | ||
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.132 | ||
| Sall3 | sal-like 3 (Drosophila) | 0.131 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.131 | ||
| Sox2 | SRY-box containing gene 2 | 0.119 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.105 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.093 | ||
| Insm1 | insulinoma-associated 1 | 0.078 | ||
| Sall4 | sal-like 4 (Drosophila) | 0.076 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.075 | ||
| Atoh7 | atonal homolog 7 (Drosophila) | 0.067 | ||
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.062 | ||
| Fgf8 | fibroblast growth factor 8 | 0.062 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.061 | ||
| Pax2 | paired box gene 2 | 0.051 | ||
| Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 | 0.048 | ||
| Chrd | chordin | 0.048 | ||
| Vax1 | ventral anterior homeobox containing gene 1 | 0.048 | ||
| Nkx6-1 | NK6 homeobox 1 | 0.045 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.045 | ||
| Rarg | retinoic acid receptor, gamma | 0.042 | ||
| Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.040 | ||
| Sox9 | SRY-box containing gene 9 | 0.038 | ||
| Lhx3 | LIM homeobox protein 3 | 0.038 | ||
| S100a11 | S100 calcium binding protein A11 (calgizzarin) | 0.038 | ||
| Pax6 | paired box gene 6 | 0.037 | ||
| Sox11 | SRY-box containing gene 11 | 0.037 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.037 | ||
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.035 | ||
| Pax3 | paired box gene 3 | 0.035 | ||
| Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 0.031 | ||
| Sox3 | SRY-box containing gene 3 | 0.030 | ||
| Tlx3 | T-cell leukemia, homeobox 3 | 0.030 | ||
| Gja5 | gap junction protein, alpha 5 | 0.029 | ||
| Bcar1 | breast cancer anti-estrogen resistance 1 | 0.029 | ||
| Nog | noggin | 0.029 | ||
| S100a6 | S100 calcium binding protein A6 (calcyclin) | 0.029 | ||
| Foxe1 | forkhead box E1 | 0.026 | ||
| Dlx1 | distal-less homeobox 1 | 0.026 | ||
| Zbtb7b | zinc finger and BTB domain containing 7B | 0.025 | ||
| Vegfa | vascular endothelial growth factor A | 0.025 | ||
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.025 | ||
| Lhx5 | LIM homeobox protein 5 | 0.024 | ||
| S100a10 | S100 calcium binding protein A10 (calpactin) | 0.024 | ||
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.024 | ||
| Foxh1 | forkhead box H1 | 0.024 | ||
| Hoxa13 | homeobox A13 | 0.022 | ||
| Ntf3 | neurotrophin 3 | 0.022 | ||
| Nodal | nodal | 0.021 | ||
| Foxa2 | forkhead box A2 | 0.021 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.020 | ||
| Cd22 | CD22 antigen | 0.019 | ||
| Alx4 | aristaless-like homeobox 4 | 0.019 | ||
| S100a4 | S100 calcium binding protein A4 | 0.019 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.018 | ||
| T | brachyury | 0.018 | ||
| Sox1 | SRY-box containing gene 1 | 0.018 | ||
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.018 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.018 | ||
| Pnoc | prepronociceptin | 0.017 | ||
| Nanog | Nanog homeobox | 0.017 | ||
| Wnt6 | wingless-related MMTV integration site 6 | 0.017 | ||
| 2010106G01Rik | RIKEN cDNA 2010106G01 gene | 0.017 | ||
| Akp3 | alkaline phosphatase 3, intestine, not Mn requiring | 0.017 | ||
| Foxb1 | forkhead box B1 | 0.016 | ||
| Tbx5 | T-box 5 | 0.016 | ||
| Cyld | cylindromatosis (turban tumor syndrome) | 0.016 | ||
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.016 | ||
| Capg | capping protein (actin filament), gelsolin-like | 0.016 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.016 | ||
| Neurod1 | neurogenic differentiation 1 | 0.016 | ||
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.016 | ||
| Gp9 | glycoprotein 9 (platelet) | 0.015 | ||
| Atoh1 | atonal homolog 1 (Drosophila) | 0.015 | ||
| Cdx1 | caudal type homeobox 1 | 0.015 | ||
| Wnt2b | wingless related MMTV integration site 2b | 0.014 | ||
| Lalba | lactalbumin, alpha | 0.014 | ||
| Homer1 | homer homolog 1 (Drosophila) | 0.014 | ||
| Cabp2 | calcium binding protein 2 | 0.014 | ||
| Pax8 | paired box gene 8 | 0.014 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.014 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.014 | ||
| Nrtn | neurturin | 0.014 | ||
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.014 | ||
| Sox4 | SRY-box containing gene 4 | 0.013 | ||
| Opn4 | opsin 4 (melanopsin) | 0.013 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.013 | ||
| Ighmbp2 | immunoglobulin mu binding protein 2 | 0.013 | ||
| Gna15 | guanine nucleotide binding protein, alpha 15 | 0.013 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.013 | ||
| Gh | growth hormone | 0.013 | ||
| Lhx1 | LIM homeobox protein 1 | 0.013 | ||
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.013 | ||
| Tlx2 | T-cell leukemia, homeobox 2 | 0.013 | ||
| Zscan2 | zinc finger and SCAN domain containing 2 | 0.012 | ||
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.012 | Mouse | |
| Hoxd3 | homeobox D3 | 0.012 | ||
| Zfpm2 | zinc finger protein, multitype 2 | 0.012 | ||
| Fgf3 | fibroblast growth factor 3 | 0.012 | ||
| Galr2 | galanin receptor 2 | 0.012 | ||
| Zic2 | zinc finger protein of the cerebellum 2 | 0.012 | ||
| Foxg1 | forkhead box G1 | 0.012 | ||
| Kcnj5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.012 | ||
| Ascl2 | achaete-scute complex homolog 2 (Drosophila) | 0.012 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.011 | ||
| Fgf17 | fibroblast growth factor 17 | 0.011 | ||
| Rxra | retinoid X receptor alpha | 0.011 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.011 | ||
| Hoxd13 | homeobox D13 | 0.011 | ||
| Foxc2 | forkhead box C2 | 0.011 | ||
| Gipc3 | GIPC PDZ domain containing family, member 3 | 0.011 | ||
| Prop1 | paired like homeodomain factor 1 | 0.011 | ||
| Mesp1 | mesoderm posterior 1 | 0.011 | ||
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.011 | ||
| Msx3 | homeobox, msh-like 3 | 0.011 | ||
| Gata6 | GATA binding protein 6 | 0.011 | ||
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.011 | ||
| Sufu | suppressor of fused homolog (Drosophila) | 0.011 | ||
| Gata4 | GATA binding protein 4 | 0.011 | ||
| Gsc | goosecoid homeobox | 0.010 | ||
| Crabp1 | cellular retinoic acid binding protein I | 0.010 | ||
| Nr2f1 | nuclear receptor subfamily 2, group F, member 1 | 0.010 | ||
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.010 | ||
| Wnt7b | wingless-related MMTV integration site 7B | 0.010 | ||
| Adra1b | adrenergic receptor, alpha 1b | 0.010 | ||
| Prkcd | protein kinase C, delta | 0.010 | ||
| Neurog3 | neurogenin 3 | 0.010 | ||
| Hoxd11 | homeobox D11 | 0.010 | ||
| Gal | galanin | 0.010 | ||
| Jag1 | jagged 1 | 0.010 |