IMP

Process View

Rattus norvegicus

11 genes annotated in rat

drug metabolic process

The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.

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In addition to gene-name show these genes:

Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "drug metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "drug metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Cyp2a1	cytochrome P450, family 2, subfamily a, polypeptide 1	0.996	Rat
Cyp2b1	cytochrome P450, family 2, subfamily b, polypeptide 1	0.989
Cyp3a18	cytochrome P450, family 3, subfamily a, polypeptide 18	0.982	Human Rat
Ugt2b1	UDP glucuronosyltransferase 2 family, polypeptide B1	0.934
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.930
Sult1e1	sulfotransferase family 1E, estrogen-preferring, member 1	0.929	Rat
Ugt2b	UDP glycosyltransferase 2 family, polypeptide B	0.821
Cyp2d4	cytochrome P450, family 2, subfamily d, polypeptide 4	0.769
Apob	apolipoprotein B	0.735
Fmo3	flavin containing monooxygenase 3	0.719
Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	0.671
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.660	Human Rat
Cyp4a10	cytochrome P450, family 4, subfamily a, polypeptide 10	0.653
Sult1a1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	0.613
Cyp2a2	cytochrome P450, family 2, subfamily a, polypeptide 2	0.571	Rat
LOC293989	cytochrome P450-like	0.568	Rat
Abcc6	ATP-binding cassette, subfamily C (CFTR/MRP), member 6	0.528
Cyp3a2	cytochrome P450, family 3, subfamily a, polypeptide 2	0.461
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.436	Human
Cyp2d3	cytochrome P450, family 2, subfamily d, polypeptide 3	0.422	Human Rat
Cyp4f1	cytochrome P450, family 4, subfamily f, polypeptide 1	0.369	Rat
Cyp2c22	cytochrome P450, family 2, subfamily c, polypeptide 22	0.328	Rat
Slc22a7	solute carrier family 22 (organic anion transporter), member 7	0.296
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.295	Rat
Cyp2d2	cytochrome P450, family 2, subfamily d, polypeptide 2	0.292	Human Rat
Sult1b1	sulfotransferase family, cytosolic, 1B, member 1	0.291	Rat
Abcb11	ATP-binding cassette, subfamily B (MDR/TAP), member 11	0.281
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.271	Rat
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.262
Cyp2f4	cytochrome P450, family 2, subfamily f, polypeptide 4	0.235	Rat
Fmo1	flavin containing monooxygenase 1	0.233	Mouse Rat
Sult1c3	sulfotransferase family, cytosolic, 1C, member 3	0.220	Rat
Adh4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.189
Ces1e	carboxylesterase 1E	0.180
Ces1c	carboxylesterase 1C	0.154
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.153
Slco1b3	solute carrier organic anion transporter family, member 1b3	0.136
Acot12	acyl-CoA thioesterase 12	0.136
Cyp2c11	cytochrome P450, subfamily 2, polypeptide 11	0.135	Human Rat
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.126
Cyp4a2	cytochrome P450, family 4, subfamily a, polypeptide 2	0.120	Rat
Cyp3a23/3a1	cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1	0.108
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.099
Gsta2	glutathione S-transferase A2	0.098
Omd	osteomodulin	0.091
Cps1	carbamoyl-phosphate synthetase 1	0.087
Dhfr	dihydrofolate reductase	0.086
Slco1a4	solute carrier organic anion transporter family, member 1a4	0.083
Cyp2b2	cytochrome P450, family 2, subfamily b, polypeptide 2	0.081
Crygf	crystallin, gamma F	0.076
Otc	ornithine carbamoyltransferase	0.076
Aqp9	aquaporin 9	0.073
G6pc	glucose-6-phosphatase, catalytic subunit	0.072
Fmo2	flavin containing monooxygenase 2	0.070	Human Rat
Mettl7b	methyltransferase like 7B	0.070
LOC100365112	carboxylesterase-like	0.069
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.062
Dpys	dihydropyrimidinase	0.062
A1i3	alpha-1-inhibitor III	0.061
Cyp4a3	cytochrome P450, family 4, subfamily a, polypeptide 3	0.060	Rat
Krtcap2	keratinocyte associated protein 2	0.059
Acsm5	acyl-CoA synthetase medium-chain family member 5	0.056
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.053
Hsd17b6	hydroxysteroid (17-beta) dehydrogenase 6	0.052
Gnmt	glycine N-methyltransferase	0.049
Adh1	alcohol dehydrogenase 1 (class I)	0.048
Zfp37	zinc finger protein 37	0.047
LOC494499	LOC494499 protein	0.047
Slco1a1	solute carrier organic anion transporter family, member 1a1	0.044
Cyp2d1	cytochrome P450, family 2, subfamily d, polypeptide 1	0.044
Hnf4a	hepatocyte nuclear factor 4, alpha	0.043
Akr1c12	aldo-keto reductase family 1, member C12	0.043
Fabp1	fatty acid binding protein 1, liver	0.041
Ugt2b7	UDP glucuronosyltransferase 2 family, polypeptide B7	0.041
Ugt2b37	UDP-glucuronosyltransferase 2 family, member 37	0.040
Ces2c	carboxylesterase 2C	0.037
Ces1f	carboxylesterase 1F	0.034
Cyp2c23	cytochrome P450, family 2, subfamily c, polypeptide 23	0.034	Rat
Akr1c18	aldo-keto reductase family 1, member C18	0.033
Hmgcs2	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)	0.032
Cyp3a9	cytochrome P450, family 3, subfamily a, polypeptide 9	0.031	Human Rat
Cyp4a8	cytochrome P450, family 4, subfamily a, polypeptide 8	0.030	Rat
Efcab4a	EF-hand calcium binding domain 4A	0.029
Abcc2	ATP-binding cassette, subfamily C (CFTR/MRP), member 2	0.028
Cml3	camello-like 3	0.026
Fdxr	ferredoxin reductase	0.024
Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.024
Sult2a1	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.024
Akr1c14	aldo-keto reductase family 1, member C14	0.024
Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.022
Cyp2j3	cytochrome P450, family 2, subfamily j, polypeptide 3	0.021
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.020
LOC100361864	UDP-glucuronosyltransferase 2B3-like	0.019
Pon1	paraoxonase 1	0.019
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.018
Akr1c1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.018
Srd5a2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	0.018
Cyp4f6	cytochrome P450, family 4, subfamily f, polypeptide 6	0.018	Rat
Afm	afamin	0.017
Mgst2	microsomal glutathione S-transferase 2	0.017
Cyp2b3	cytochrome P450, family 2, subfamily b, polypeptide 3	0.016
Azgp1	alpha-2-glycoprotein 1, zinc-binding	0.016
Slc10a2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	0.016
Rxrg	retinoid X receptor gamma	0.016
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.016
Ces1d	carboxylesterase 1D	0.015
Fut1	fucosyltransferase 1	0.015
L3mbtl3	l(3)mbt-like 3 (Drosophila)	0.015
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.015
Acy3	aspartoacylase (aminocyclase) 3	0.013
Hal	histidine ammonia lyase	0.013
Fgd4	FYVE, RhoGEF and PH domain containing 4	0.013
Galnt5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	0.013
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.013
LOC100361547	Cytochrome P450, family 2, subfamily c, polypeptide 7-like	0.013
Dpyd	dihydropyrimidine dehydrogenase	0.013
Gulo	gulonolactone (L-) oxidase	0.012
Lepr	leptin receptor	0.012
Mucdhl	mucin and cadherin like	0.012
Prl8a9	prolactin family 8, subfamily a, member 9	0.012
Fgfr4	fibroblast growth factor receptor 4	0.012
Vom1r102	vomeronasal 1 receptor 102	0.012
Ppara	peroxisome proliferator activated receptor alpha	0.011
Olr1701	olfactory receptor 1701	0.011
LOC680367	similar to Urinary protein 3 precursor (RUP-3)	0.011
Vegp1	von Ebners gland protein 1	0.011
Cyp2c7	cytochrome P450, family 2, subfamily c, polypeptide 7	0.011
Gstm3	glutathione S-transferase mu 3	0.011
Fgb	fibrinogen beta chain	0.011
Olr59	olfactory receptor 59	0.011
Gstm2	glutathione S-transferase mu 2	0.011
LOC299282	Serine protease inhibitor	0.011
Gabrr2	gamma-aminobutyric acid (GABA) receptor, rho 2	0.011
LOC287004	Mg1 protein	0.010
Cyp17a1	cytochrome P450, family 17, subfamily a, polypeptide 1	0.010