IMP

Process View

Rattus norvegicus

1 genes annotated in rat

positive regulation of the force of heart contraction by epinephrine

The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of the force of heart contraction by epinephrine"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of the force of heart contraction by epinephrine" (in gray)

Name	Description	Probability	Func Analog Organism
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.177
Fgf14	fibroblast growth factor 14	0.101
Hrh1	histamine receptor H 1	0.094
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.092
Syt8	synaptotagmin VIII	0.090
Ddn	dendrin	0.087
Arhgap23	Rho GTPase activating protein 23	0.081
Fgf2	fibroblast growth factor 2	0.079
Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7	0.077
Olr287	olfactory receptor 287	0.062
Tacr2	tachykinin receptor 2	0.062
Dlg4	discs, large homolog 4 (Drosophila)	0.060
Svs3a	seminal vesicle secretory protein 3A	0.059
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.058
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.055
Vcsa1	variable coding sequence A1	0.054
Cxcr5	chemokine (C-X-C motif) receptor 5	0.052
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.048
Gja3	gap junction protein, alpha 3	0.048
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.048
Srd5a2	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	0.047
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.046
Egr3	early growth response 3	0.046
Ar	androgen receptor	0.046
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.046
Foxe3	forkhead box E3	0.046
Kcnq2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.044
Insrr	insulin receptor-related receptor	0.043
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.043
Oprd1	opioid receptor, delta 1	0.042
Gria1	glutamate receptor, ionotropic, AMPA 1	0.041
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.041
Svs1	seminal vesicle secretory protein 1	0.040
Ucn	urocortin	0.040
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.040
Hpcal4	hippocalcin-like 4	0.040
Crhbp	corticotropin releasing hormone binding protein	0.040
Grm6	glutamate receptor, metabotropic 6	0.040
Grik3	glutamate receptor, ionotropic, kainate 3	0.039
C1qtnf6	C1q and tumor necrosis factor related protein 6	0.038
Prl4a1	prolactin family 4, subfamily a, member 1	0.038
Dspp	dentin sialophosphoprotein	0.037
Cga	glycoprotein hormones, alpha polypeptide	0.037
Htr1b	5-hydroxytryptamine (serotonin) receptor 1B	0.037	Rat
Aqp5	aquaporin 5	0.036
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.035
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.035
RGD1564664	similar to LOC387763 protein	0.035
Fgf7	fibroblast growth factor 7	0.035
Olr1500	olfactory receptor 1500	0.035
Npy5r	neuropeptide Y receptor Y5	0.034
Il2ra	interleukin 2 receptor, alpha	0.034
Adrb1	adrenergic, beta-1-, receptor	0.033	Rat
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.033
Prm2	protamine 2	0.033
Gabrg3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.032
Fgfr2	fibroblast growth factor receptor 2	0.032
Mcpt1	mast cell protease 1	0.032
Sstr5	somatostatin receptor 5	0.032
Vom2r44	vomeronasal 2 receptor 44	0.032
Nr2c2	nuclear receptor subfamily 2, group C, member 2	0.031
Reg3a	regenerating islet-derived 3 alpha	0.030
Cma1	chymase 1, mast cell	0.030
LOC60591	calcium-activated potassium channel beta subunit	0.029
Testin	testin gene	0.029
Cxcl2	chemokine (C-X-C motif) ligand 2	0.029
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.029
Aqp2	aquaporin 2 (collecting duct)	0.028
Epha8	Eph receptor A8	0.028
Pth	parathyroid hormone	0.028
Adra2a	adrenergic, alpha-2A-, receptor	0.028
Vdr	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.028
Atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.028
Htr2a	5-hydroxytryptamine (serotonin) receptor 2A	0.027	Rat
RGD1565859	RGD1565859	0.027
Ier5	immediate early response 5	0.027
Neurog1	neurogenin 1	0.027
Csrnp2	cysteine-serine-rich nuclear protein 2	0.027
Ehf	ets homologous factor	0.027
Adam2	ADAM metallopeptidase domain 2	0.027
Hnmt	histamine N-methyltransferase	0.027
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.026
Rgs9	regulator of G-protein signaling 9	0.026
Efna5	ephrin A5	0.026
Ifnb1	interferon beta 1, fibroblast	0.026
Iapp	islet amyloid polypeptide	0.026
Olr416	olfactory receptor 416	0.026
Grik1	glutamate receptor, ionotropic, kainate 1	0.026
Ucp1	uncoupling protein 1 (mitochondrial, proton carrier)	0.025
Odf4	outer dense fiber of sperm tails 4	0.025
Slc17a7	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7	0.025
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.025
Esr1	estrogen receptor 1	0.025
Gria4	glutamate receptor, ionotrophic, AMPA 4	0.024
Rorb	RAR-related orphan receptor B	0.024
Phkg1	phosphorylase kinase, gamma 1	0.024
Trib1	tribbles homolog 1 (Drosophila)	0.024
Grid1	glutamate receptor, ionotropic, delta 1	0.024
Adarb2	adenosine deaminase, RNA-specific, B2	0.024
Cd5	Cd5 molecule	0.024
Gpr27	G protein-coupled receptor 27	0.023
Gad2	glutamate decarboxylase 2	0.023
Cckar	cholecystokinin A receptor	0.023
Nlgn2	neuroligin 2	0.023
Chrna1	cholinergic receptor, nicotinic, alpha 1 (muscle)	0.023
Necab1	N-terminal EF-hand calcium binding protein 1	0.023
Chrm5	cholinergic receptor, muscarinic 5	0.023
Gabra3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.023
Tacr1	tachykinin receptor 1	0.023
Pdc	phosducin	0.023
Pitx3	paired-like homeodomain 3	0.023
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.022
Dusp4	dual specificity phosphatase 4	0.022
Itgad	integrin, alpha D	0.022
Mchr1	melanin-concentrating hormone receptor 1	0.022
Rph3a	rabphilin 3A	0.022
Gast	gastrin	0.022
Ptgdr	prostaglandin D receptor	0.022
Gng7	guanine nucleotide binding protein (G protein), gamma 7	0.022
Gpr6	G protein-coupled receptor 6	0.022
Ctrc	chymotrypsin C (caldecrin)	0.022
Prl3d1	Prolactin family 3, subfamily d, member 1	0.022
Mas1	MAS1 oncogene	0.022
Pcsk1	proprotein convertase subtilisin/kexin type 1	0.022
Pex5l	peroxisomal biogenesis factor 5-like	0.022
RGD1564327	similar to integrin alpha 8	0.022
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.021
Musk	muscle, skeletal, receptor tyrosine kinase	0.021
Twist2	twist homolog 2 (Drosophila)	0.021
Gjb3	gap junction protein, beta 3	0.021
Cd8b	CD8b molecule	0.021
LOC286987	hemiferrin, transferrin-like protein	0.021
Sycn	syncollin	0.021
Mmp13	matrix metallopeptidase 13	0.020
Fam70b	family with sequence similarity 70, member B	0.020
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.020
Klk8	kallikrein related-peptidase 8	0.020
Vom1r93	vomeronasal 1 receptor 93	0.020
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.020
Slit1	slit homolog 1 (Drosophila)	0.020
Cfp	complement factor properdin	0.020
LOC293989	cytochrome P450-like	0.020
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.020
Mbl2	mannose-binding lectin (protein C) 2	0.020
Gcm1	glial cells missing homolog 1 (Drosophila)	0.019
Adrbk2	adrenergic, beta, receptor kinase 2	0.019
Syt6	synaptotagmin VI	0.019
Hspa1l	heat shock protein 1-like	0.019
Dmd	dystrophin	0.019
Kalrn	kalirin, RhoGEF kinase	0.019
Mc5r	melanocortin 5 receptor	0.019
Col10a1	collagen, type X, alpha 1	0.019
Gjb5	gap junction protein, beta 5	0.019
Gfi1	growth factor independent 1 transcription repressor	0.019
Alox5	arachidonate 5-lipoxygenase	0.019
Prp15	proline-rich protein 15	0.018
Scnn1b	sodium channel, nonvoltage-gated 1, beta	0.018
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.018
Gpr1	G protein-coupled receptor 1	0.018
Cpa3	carboxypeptidase A3, mast cell	0.018
Tnni1	troponin I type 1 (skeletal, slow)	0.018
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.018
Nlgn1	neuroligin 1	0.018
Gabrr3	gamma-aminobutyric acid (GABA) receptor, rho 3	0.018
Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	0.017
Asph	aspartate-beta-hydroxylase	0.017
Adcyap1r1	adenylate cyclase activating polypeptide 1 receptor 1	0.017
Kl	Klotho	0.017
Synpo	synaptopodin	0.017
Cyp2b12	cytochrome P450, family 2, subfamily b, polypeptide 12	0.017
Kcnk4	potassium channel, subfamily K, member 4	0.017
Folh1	folate hydrolase 1	0.017
Ppp1r9a	protein phosphatase 1, regulatory (inhibitor) subunit 9A	0.017
Lck	lymphocyte-specific protein tyrosine kinase	0.017
Otx1	orthodenticle homeobox 1	0.017
Adam3a	ADAM metallopeptidase domain 3A (cyritestin 1)	0.017
Edn1	endothelin 1	0.017
Gucy2f	guanylate cyclase 2F	0.017
Tnp2	transition protein 2	0.017
Myt1l	myelin transcription factor 1-like	0.017
Hes2	hairy and enhancer of split 2 (Drosophila)	0.017
Dlx5	distal-less homeobox 5	0.016
Ccbp2	chemokine binding protein 2	0.016
Rgs8	regulator of G-protein signaling 8	0.016
Bglap	bone gamma-carboxyglutamate (gla) protein	0.016
Lsm6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.016
Syngap1	synaptic Ras GTPase activating protein 1 homolog (rat)	0.016
Edn2	endothelin 2	0.016
Vom2r53	vomeronasal 2 receptor, 53	0.016
Chrm1	cholinergic receptor, muscarinic 1	0.016
Pgc	progastricsin (pepsinogen C)	0.016
Cdh17	cadherin 17	0.016
Dapk2	death-associated kinase 2	0.016
Sox17	SRY (sex determining region Y)-box 17	0.016
Cd247	Cd247 molecule	0.016
Grifin	galectin-related inter-fiber protein	0.016
Ppy	pancreatic polypeptide	0.016
Zp1	zona pellucida glycoprotein 1 (sperm receptor)	0.016
Hes3	hairy and enhancer of split 3 (Drosophila)	0.016
Foxi2	forkhead box I2	0.016
Ugt2a1	UDP glucuronosyltransferase 2 family, polypeptide A1	0.016
Gabbr1	gamma-aminobutyric acid (GABA) B receptor 1	0.016
Trhr	thyrotropin releasing hormone receptor	0.016
Amph	amphiphysin	0.016
Fam38b	family with sequence similarity 38, member B	0.016
Ocm	oncomodulin	0.016
Galr1	galanin receptor 1	0.016
Mgat5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	0.015
Slc28a3	solute carrier family 28 (sodium-coupled nucleoside transporter), member 3	0.015
Sstr1	somatostatin receptor 1	0.015
Cxcl10	chemokine (C-X-C motif) ligand 10	0.015
Btc	betacellulin	0.015
Chrnb2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.015
Smad3	SMAD family member 3	0.015
Csn2	casein beta	0.015
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.015
Dnah2	dynein, axonemal, heavy chain 2	0.015
N5	DNA binding protein N5	0.015
Nkx6-1	NK6 homeobox 1	0.015
Syt10	synaptotagmin X	0.015
Mybpc2	myosin binding protein C, fast-type	0.015
Il13	interleukin 13	0.015
Il7	interleukin 7	0.015
Mmp10	matrix metallopeptidase 10	0.015
Akap4	A kinase (PRKA) anchor protein 4	0.015
Afap1	actin filament associated protein 1	0.015
Scn7a	sodium channel, voltage-gated, type VII, alpha	0.015
Cd80	Cd80 molecule	0.014
Fgf17	fibroblast growth factor 17	0.014
Mpp2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	0.014
LOC100361571	keratin associated protein 1-3-like	0.014
Gabrp	gamma-aminobutyric acid (GABA-A) receptor, pi	0.014
A3galt2	alpha 1,3-galactosyltransferase 2	0.014
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.014
Prrx1	paired related homeobox 1	0.014
Tff2	trefoil factor 2	0.014
Vom2r27	vomeronasal 2 receptor, 27	0.014
Hand1	heart and neural crest derivatives expressed 1	0.014
Slc30a2	solute carrier family 30 (zinc transporter), member 2	0.014
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.014
Il1rn	interleukin 1 receptor antagonist	0.014
Ceacam3	carcinoembryonic antigen-related cell adhesion molecule 3	0.014
RGD1560784	similar to RIKEN cDNA B630019K06	0.014
Agtr1a	angiotensin II receptor, type 1a	0.014
Sgp158	proline-rich glycoprotein (sgp158)	0.014
Pvalb	parvalbumin	0.014
Gpr20	G protein-coupled receptor 20	0.014
Hapln1	hyaluronan and proteoglycan link protein 1	0.014
Cartpt	CART prepropeptide	0.014
Ncan	neurocan	0.014
Gabra5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	0.014
Kcng3	potassium voltage-gated channel, subfamily G, member 3	0.014
Ton	tonin	0.013
Hrh3	histamine receptor H3	0.013
Rasa2	RAS p21 protein activator 2	0.013
RT1-M4	RT1 class Ib, locus M4	0.013
Sfrp4	secreted frizzled-related protein 4	0.013
Prl	prolactin	0.013
Slc2a13	solute carrier family 2 (facilitated glucose transporter), member 13	0.013
Pnmt	phenylethanolamine-N-methyltransferase	0.013
Clstn3	calsyntenin 3	0.013
Padi1	peptidyl arginine deiminase, type I	0.013
Tat	tyrosine aminotransferase	0.013
Pax4	paired box 4	0.013
Pfkfb4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	0.013
Dhrs9	dehydrogenase/reductase (SDR family) member 9	0.013
Hpca	hippocalcin	0.013
Sert1	Sertoli cell protein 1	0.013
Ros1	c-ros oncogene 1 , receptor tyrosine kinase	0.013
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.013
Myog	myogenin	0.013
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.013
Adora1	adenosine A1 receptor	0.013
Cd79b	Cd79b molecule, immunoglobulin-associated beta	0.013
Foxg1	forkhead box G1	0.012
Adra1a	adrenergic, alpha-1A-, receptor	0.012
Slc5a1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.012
Adam7	ADAM metallopeptidase domain 7	0.012
Gcg	glucagon	0.012
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.012
Cdkn2b	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.012
Crybb2	crystallin, beta B2	0.012
Olr1078	olfactory receptor 1078	0.012
Znf483	zinc finger protein 483	0.012
Ldhc	lactate dehydrogenase C	0.012
Fgf23	fibroblast growth factor 23	0.012
Nptxr	neuronal pentraxin receptor	0.012
Chia	chitinase, acidic	0.012
Mr1	major histocompatibility complex, class I-related	0.012
Il17re	interleukin 17 receptor E	0.012
Chrne	cholinergic receptor, nicotinic, epsilon	0.012
Lif	leukemia inhibitory factor	0.012
Smgb	neonatal submandibular gland protein B	0.012
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.012
Cckbr	cholecystokinin B receptor	0.012
Umod	uromodulin	0.012
Epha7	Eph receptor A7	0.012
Tpsb2	tryptase beta 2	0.012
Chst3	carbohydrate (chondroitin 6) sulfotransferase 3	0.012
Accn2	amiloride-sensitive cation channel 2, neuronal	0.012
Slc22a2	solute carrier family 22 (organic cation transporter), member 2	0.012
Pspn	persephin	0.012
Csf3	colony stimulating factor 3 (granulocyte)	0.012
Gpr88	G-protein coupled receptor 88	0.012
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.012
Bhlha15	basic helix-loop-helix family, member a15	0.012
Adora3	adenosine A3 receptor	0.012
Hist1h2aa	histone cluster 1, H2aa	0.012
Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1	0.011
Clec11a	C-type lectin domain family 11, member a	0.011
Rho	rhodopsin	0.011
Cd3d	CD3 molecule, delta	0.011
Mmp3	matrix metallopeptidase 3	0.011
Gna11	guanine nucleotide binding protein, alpha 11	0.011
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.011
Sec1	secretory blood group 1	0.011
Cdh6	cadherin 6	0.011
Isl2	ISL LIM homeobox 2	0.011
Scn10a	sodium channel, voltage-gated, type X, alpha subunit	0.011
Tmem59l	transmembrane protein 59-like	0.011
Selp	selectin P	0.011
Gabra4	gamma-aminobutyric acid (GABA) A receptor, alpha 4	0.011
Kitlg	KIT ligand	0.011
Ptprq	protein tyrosine phosphatase, receptor type, Q	0.011
Plcd4	phospholipase C, delta 4	0.011
LOC100365904	hypothetical protein LOC100365904	0.011
Chrnb3	cholinergic receptor, nicotinic, beta 3	0.011
Kcns1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1	0.011
Nlrp6	NLR family, pyrin domain containing 6	0.011
Cmklr1	chemokine-like receptor 1	0.011
Galr3	galanin receptor 3	0.011
Lepr	leptin receptor	0.011
Nxph1	neurexophilin 1	0.011
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.011
Ccl4	chemokine (C-C motif) ligand 4	0.011
Fibcd1	fibrinogen C domain containing 1	0.011
Neurod2	neurogenic differentiation 2	0.011
Dbc1	deleted in bladder cancer 1 (human)	0.011
Agtr1b	angiotensin II receptor, type 1b	0.011
Reg1a	regenerating islet-derived 1 alpha	0.011
Dck	deoxycytidine kinase	0.011
Itpka	inositol 1,4,5-trisphosphate 3-kinase A	0.011
Grm5	glutamate receptor, metabotropic 5	0.011
Oprl1	opiate receptor-like 1	0.011
Pde1b	phosphodiesterase 1B, calmodulin-dependent	0.011
Tas2r126	taste receptor, type 2, member 126	0.011
Akap14	A kinase (PRKA) anchor protein 14	0.011
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.011
Guca2a	guanylate cyclase activator 2a (guanylin)	0.011
Rab15	RAB15, member RAS oncogene family	0.011
Accn3	amiloride-sensitive cation channel 3	0.011
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.011
Rgs14	regulator of G-protein signaling 14	0.011
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.010
Naaladl1	N-acetylated alpha-linked acidic dipeptidase-like 1	0.010
Otud7a	OTU domain containing 7A	0.010
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.010
Pomc	proopiomelanocortin	0.010
Abp10	annexin V-binding protein ABP-10	0.010
Krtap1-5	keratin associated protein 1-5	0.010
Gfpt1	glutamine fructose-6-phosphate transaminase 1	0.010
Plau	plasminogen activator, urokinase	0.010
Calcb	calcitonin-related polypeptide, beta	0.010
Mmp9	matrix metallopeptidase 9	0.010
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.010
Il10	interleukin 10	0.010
Fgf8	fibroblast growth factor 8	0.010
Ccr2	chemokine (C-C motif) receptor 2	0.010
Tpbpa	trophoblast specific protein alpha	0.010
Drd2	dopamine receptor D2	0.010
Pou3f2	POU class 3 homeobox 2	0.010
Fcer2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.010
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.010
Nov	nephroblastoma overexpressed gene	0.010
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.010
Fgf5	fibroblast growth factor 5	0.010