IMP

Process View

Saccharomyces cerevisiae

18 genes annotated in yeast

mitotic dna integrity checkpoint

A mitotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.

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Known genes in the process in yeast Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mitotic dna integrity checkpoint"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mitotic dna integrity checkpoint" (in gray)

Name	Description	Probability	Func Analog Organism
POL30	Pol30p	0.254
RAD52	Rad52p	0.195
BUB3	Bub3p	0.179
RPB3	Rpb3p	0.177
CDC6	Cdc6p	0.153
RAD53	Rad53p	0.147
MCM6	Mcm6p	0.131
SPT5	Spt5p	0.120
RPO26	Rpo26p	0.106
MCM2	Mcm2p	0.104
TOF1	Tof1p	0.095
BUB1	Bub1p	0.087
MRC1	Mrc1p	0.084
DBF4	Dbf4p	0.082
PSF1	Psf1p	0.080
MCM4	Mcm4p	0.080
RCO1	Rco1p	0.079
MCM10	Mcm10p	0.075
ASF1	Asf1p	0.063
DPB11	Dpb11p	0.060
MAD2	Mad2p	0.057
DPB2	Dpb2p	0.054
CTF4	Ctf4p	0.051
SRS2	Srs2p	0.049
CDC20	Cdc20p	0.048
GBP2	Gbp2p	0.048
SLD2	Sld2p	0.044
MAD3	Mad3p	0.041
LCD1	Lcd1p	0.041
ELG1	Elg1p	0.041
RFA1	Rfa1p	0.040
THP2	Thp2p	0.037
RRM3	Rrm3p	0.035
MPT5	Mpt5p	0.035
RPB10	Rpb10p	0.034
MCM5	Mcm5p	0.033
RIF1	Rif1p	0.032
CTF18	Ctf18p	0.030
RAD17	Rad17p	0.026
SWI4	Swi4p	0.026
DST1	Dst1p	0.026
KEM1	Kem1p	0.026
POL2	Pol2p	0.025
RAD24	Rad24p	0.025
RTF1	Rtf1p	0.024
MSA1	Msa1p	0.024
POL1	Pol1p	0.023
CLN3	Cln3p	0.023
RAD27	Rad27p	0.021
UBC4	Ubc4p	0.021
POL32	Pol32p	0.021
MGS1	Mgs1p	0.021
TEL1	Tel1p	0.020
MAD1	Mad1p	0.020
YLR264C-A	hypothetical protein	0.020
POL3	Pol3p	0.020
ZIP1	Zip1p	0.020
HO	Hop	0.020
SLD3	Sld3p	0.019
SRD1	Srd1p	0.019
ADH2	Adh2p	0.019
SCC2	Scc2p	0.019
YLR162W	hypothetical protein	0.019
DNA2	Dna2p	0.019
PEX22	Pex22p	0.019
GIC1	Gic1p	0.018
LEU2	Leu2p	0.018
TIF4632	Tif4632p	0.017
SLK19	Slk19p	0.017
CUP1-1	Cup1-1p	0.017
SAS4	Sas4p	0.017
SUB2	Sub2p	0.017
SGS1	Sgs1p	0.017
MTW1	Mtw1p	0.017
ZDS2	Zds2p	0.016
SDC1	Sdc1p	0.016
HHT2	Hht2p	0.016
MF(ALPHA)2	Mf(alpha)2p	0.016
URA3	Ura3p	0.016
YOL038C-A	hypothetical protein	0.016
ARG8	Arg8p	0.016
UME1	Ume1p	0.016
REV1	Rev1p	0.016
FAR10	Far10p	0.016
DUN1	Dun1p	0.016
SMC4	Smc4p	0.016
MMS21	Mms21p	0.016
WSS1	Wss1p	0.015
HPR1	Hpr1p	0.015
CRP1	Crp1p	0.015
HXT3	Hxt3p	0.015
CHL1	Chl1p	0.015
SLN1	Sln1p	0.015
MER1	Mer1p	0.015
MSH3	Msh3p	0.015
RPB7	Rpb7p	0.015
SWC7	Swc7p	0.015
FAR3	Far3p	0.015
PRP28	Prp28p	0.015
TYE7	Tye7p	0.014
MLH1	Mlh1p	0.014
MF(ALPHA)1	Mf(alpha)1p	0.014
YOR060C	hypothetical protein	0.014
ZPS1	Zps1p	0.014
CPR7	Cpr7p	0.014
YAR068W	hypothetical protein	0.014
MMS1	Mms1p	0.014
SCM4	Scm4p	0.013
ADA2	Ada2p	0.013
ATP6	Atp6p	0.013
DSS1	Dss1p	0.013
POL12	Pol12p	0.013
NSL1	Nsl1p	0.013
YLR042C	hypothetical protein	0.013
SOV1	Sov1p	0.013
YBL044W	hypothetical protein	0.013
CKA1	Cka1p	0.013
THP3	Thp3p	0.013
RAD10	Rad10p	0.013
SLX4	Slx4p	0.013
RFA3	Rfa3p	0.013
YOL014W	hypothetical protein	0.013
CDC21	Cdc21p	0.013
STU1	Stu1p	0.013
HPF1	Hpf1p	0.013
MUS81	Mus81p	0.013
SPL2	Spl2p	0.013
FMT1	Fmt1p	0.013
YBR013C	hypothetical protein	0.013
YPR157W	hypothetical protein	0.013
AUA1	Aua1p	0.012
CDC26	Cdc26p	0.012
VPS9	Vps9p	0.012
BNA4	Bna4p	0.012
RAD59	Rad59p	0.012
MEC1	Mec1p	0.012	Fly
YBR296C-A	hypothetical protein	0.012
PEX15	Pex15p	0.012
ARP10	Arp10p	0.012
KIP1	Kip1p	0.012
PBP2	Pbp2p	0.012
CDC73	Cdc73p	0.012
FCY21	Fcy21p	0.012
YLR040C	hypothetical protein	0.012
YGR035C	hypothetical protein	0.012
POL31	Pol31p	0.012
PTR2	Ptr2p	0.012
RAD9	Rad9p	0.012
YIR035C	hypothetical protein	0.012
PDS5	Pds5p	0.012
OPT2	Opt2p	0.012
CBP1	Cbp1p	0.012
CHA1	Cha1p	0.011
YPR096C	hypothetical protein	0.011
YOL013W-A	hypothetical protein	0.011
YJL181W	hypothetical protein	0.011
MMS22	Mms22p	0.011
NRG2	Nrg2p	0.011
MCM3	Mcm3p	0.011	Fly
PHM6	Phm6p	0.011
NFI1	Nfi1p	0.011
YJL107C	hypothetical protein	0.011
RAD5	Rad5p	0.011
YML003W	hypothetical protein	0.011
FSH1	Fsh1p	0.011
HDA2	Hda2p	0.011
YML053C	hypothetical protein	0.011
YPL216W	hypothetical protein	0.011
TCO89	Tco89p	0.011
RTT107	Rtt107p	0.011
YPL014W	hypothetical protein	0.011
PHD1	Phd1p	0.011
AIM38	Aim38p	0.011
TIR3	Tir3p	0.011
CPD1	Cpd1p	0.011
COS12	Cos12p	0.011
ENO2	Eno2p	0.011
BFR1	Bfr1p	0.011
PTI1	Pti1p	0.011
PEX2	Pex2p	0.011
ACM1	Acm1p	0.011
CDC34	Cdc34p	0.011
DIC1	Dic1p	0.010
YKR075C	hypothetical protein	0.010
RPB8	Rpb8p	0.010	Fly
CAR1	Car1p	0.010
YKR041W	hypothetical protein	0.010
CLB1	Clb1p	0.010
YAL037C-A	hypothetical protein	0.010
BSC1	Bsc1p	0.010
SRT1	Srt1p	0.010
SEN54	Sen54p	0.010
CSM1	Csm1p	0.010
MFA2	Mfa2p	0.010
BDS1	Bds1p	0.010
RNP1	Rnp1p	0.010
TIP1	Tip1p	0.010
NCE103	Nce103p	0.010
SNT1	Snt1p	0.010
AIF1	Aif1p	0.010
RPB11	Rpb11p	0.010
YNL033W	hypothetical protein	0.010
DUR1,2	Dur1,2p	0.010
YIR042C	hypothetical protein	0.010
DCC1	Dcc1p	0.010
ICS2	Ics2p	0.010
YPL067C	hypothetical protein	0.010
CUP1-2	Cup1-2p	0.010
TOF2	Tof2p	0.010