IMP

Process View

Danio rerio

5 genes annotated in zebrafish

immune response activating signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "immune response activating signal transduction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "immune response activating signal transduction" (in gray)

Name	Description	Probability	Func Analog Organism
LOC566708	FL cytokine receptor-like	0.487
ighm	immunoglobulin heavy constant mu and immunoglobulin heavy constant mu	0.461
lcp1	lymphocyte cytosolic plastin 1	0.421
epor	erythropoietin receptor	0.340
tlr3	toll-like receptor 3	0.338	Human
pdcd2	programmed cell death 2	0.198
tlr9	toll-like receptor 9	0.176
tnfb	tumor necrosis factor b (TNF superfamily, member 2)	0.127
tbx5b	T-box 5b	0.102
ighz2	immunoglobulin heavy constant zeta2	0.076
LOC100151531	zinc finger protein Gfi-1b-like	0.074
nod1	nucleotide-binding oligomerization domain containing 1	0.074
il22	interleukin 22	0.072
LOC557072	caspase recruitment domain-containing protein 11-like	0.069
ighz	immunoglobulin heavy constant zeta	0.068
stc1l	stanniocalcin 1, like	0.059
fbln4	fibulin 4	0.059
ef1a	elongation factor 1-alpha	0.058
elovl4a	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a	0.056
abcg2c	ATP-binding cassette, sub-family G (WHITE), member 2c	0.051
irak4	interleukin-1 receptor-associated kinase 4	0.050
tert	telomerase reverse transcriptase	0.043
LOC100000934	hypothetical protein LOC100000934	0.043
tlr2	toll-like receptor 2	0.042	Mouse
kdrl	kinase insert domain receptor like	0.035
fam20b	family with sequence similarity 20, member B (H. sapiens)	0.033
epas1b	endothelial PAS domain protein 1b	0.033
rag2	recombination activating gene 2	0.031
sox7	SRY-box containing gene 7	0.029
LOC100003330	melanocortin-2 receptor accessory protein 2-like	0.029
gata1a	GATA binding protein 1a	0.027
fxyd1	FXYD domain containing ion transport regulator 1 (phospholemman)	0.026
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.026	Mouse
aplp2	amyloid beta (A4) precursor-like protein 2	0.023
im:7141132	im:7141132	0.021
LOC563363	cholesterol side-chain cleavage enzyme, mitochondrial-like	0.021
c1qc	complement component 1, q subcomponent, C chain	0.021
dntt	deoxynucleotidyltransferase, terminal	0.021
yrk	Yes-related kinase	0.020
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.020
kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.020
card9	caspase recruitment domain family, member 9	0.020
pdia5	protein disulfide isomerase family A, member 5	0.020
wasb	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b	0.020
foxn1	forkhead box N1	0.020
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.019
LOC100534776	toll-like receptor 7-like	0.019
cacnb2b	calcium channel, voltage-dependent, beta 2b	0.019
grn1	granulin 1	0.019
tlr20f	toll-like receptor 20f	0.019
grn2	granulin 2	0.019
ip6k2	inositol hexaphosphate kinase 2	0.019
xylt1	xylosyltransferase 1	0.018
tlr18	toll-like receptor 18	0.017
cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)	0.017
cd40lg	CD40 ligand	0.016
bhlhe40	basic helix-loop-helix family, member e40	0.016
ccr12.2	chemokine (C-C motif) receptor 12.2	0.015
fgf23	fibroblast growth factor 23	0.015
arl4aa	ADP-ribosylation factor-like 4aa	0.014
ecscr	endothelial cell-specific chemotaxis regulator	0.014
cdh23	cadherin-like 23	0.014
tlr20a	toll-like receptor 20a	0.014
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.014	Mouse
gadd45ba	growth arrest and DNA-damage-inducible, beta a	0.014
lpp	LIM domain containing preferred translocation partner in lipoma	0.014
myd88	myeloid differentiation primary response gene (88)	0.013	Mouse
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.013
ccr6a	chemokine (C-C motif) receptor 6a	0.013
tbx21	T-box 21	0.013
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.013
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.013
LOC794824	hypothetical protein LOC794824	0.013
c1qb	complement component 1, q subcomponent, B chain	0.013
dnmt6	DNA (cytosine-5-)-methyltransferase 6	0.012
smyd3	SET and MYND domain containing 3	0.012
sb:cb429	sb:cb429	0.012
socs1	suppressor of cytokine signaling 1	0.011
cntn2	contactin 2	0.011
nos2a	nitric oxide synthase 2a, inducible	0.011
nos2b	nitric oxide synthase 2b, inducible	0.011
ftsj	FtsJ homolog 3 (E. coli)	0.010