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Danio rerio

6 genes annotated in zebrafish

t cell activation

The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "t cell activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "t cell activation" (in gray)

Name	Description	Probability	Func Analog Organism
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.535	Mouse
runx2a	runt-related transcription factor 2a	0.531	Mouse
dlc	deltaC	0.384
tp63	tumor protein p63	0.349
mmp9	matrix metalloproteinase 9	0.319
coro1a	coronin, actin binding protein, 1A	0.280	Mouse
rac2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.241
gata1a	GATA binding protein 1a	0.241
wasb	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b	0.215	Mouse
fgf3	fibroblast growth factor 3	0.211
lcp1	lymphocyte cytosolic plastin 1	0.210
ighm	immunoglobulin heavy constant mu and immunoglobulin heavy constant mu	0.201
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.185	Mouse
il7r	interleukin 7 receptor	0.176
cmyb	transcription factor cmyb	0.116	Human
runx3	runt-related transcription factor 3	0.116
mych	myelocytomatosis oncogene homolog	0.114
hspa5	heat shock protein 5	0.113
ighz	immunoglobulin heavy constant zeta	0.102
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.081
lft1	lefty1	0.079
foxa3	forkhead box A3	0.078
ptger4a	prostaglandin E receptor 4 (subtype EP4) a	0.073
cd8a	CD8 antigen, alpha polypeptide	0.066	Mouse
tfe3b	transcription factor binding to IGHM enhancer 3b	0.064
zgc:64115	zgc:64115	0.061
foxa2	forkhead box A2	0.057
dll4	delta-like 4 (Drosophila)	0.056
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.055
cldne	claudin e	0.054
nrp2b	neuropilin 2b	0.050
fgf4	fibroblast growth factor 4	0.048
fcer1gl	Fc receptor, IgE, high affinity I, gamma polypeptide like	0.048
il6r	interleukin 6 receptor	0.044
bmper	BMP binding endothelial regulator	0.042
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.039
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.038
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.038
casp3a	caspase 3, apoptosis-related cysteine protease a	0.037	Mouse
per3	period homolog 3 (Drosophila)	0.037
dntt	deoxynucleotidyltransferase, terminal	0.035
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.034
spi1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.034
fgf20a	fibroblast growth factor 20a	0.033
csrp1a	cysteine and glycine-rich protein 1a	0.031
ihha	Indian hedgehog homolog a	0.030	Mouse
sema3aa	semaphorin 3aa	0.030
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.029
cldn5b	claudin 5b	0.028
cdh1	cadherin 1, epithelial	0.027
lef1	lymphocyte enhancer binding factor 1	0.026	Mouse
tlr3	toll-like receptor 3	0.026
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.026
flh	floating head	0.025
lgals2a	lectin, galactoside-binding, soluble, 2a	0.025	Mouse
rag1	recombination activating gene 1	0.025	Mouse
shha	sonic hedgehog a	0.025	Mouse
il12bb	interleukin 12B, b	0.024	Mouse
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.024
pfn1	profilin 1	0.023
cdx4	caudal type homeo box transcription factor 4	0.022
pdgfaa	platelet-derived growth factor alpha a	0.022
gfi1.1	growth factor independent 1.1	0.022
rad21	RAD21 homolog (S. pombe)	0.021
LOC553366	hypothetical protein LOC553366	0.021
ccnd1	cyclin D1	0.021
rpl23a	ribosomal protein L23a	0.021
gata3	GATA-binding protein 3	0.021	Mouse
fes	feline sarcoma oncogene	0.020
zgc:123327	zgc:123327	0.020
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.020
her6	hairy-related 6	0.020
anxa1a	annexin A1a	0.019	Mouse
jak3	Janus kinase 3 (a protein tyrosine kinase, leukocyte)	0.019
cd247	CD247 antigen	0.019
evpl	envoplakin	0.018
mmp15b	matrix metallopeptidase 15b	0.018
rpl7a	ribosomal protein L7a	0.018
nkx2.5	NK2 transcription factor related 5	0.017
mpll	myeloproliferative leukemia virus oncogene, like	0.017
LOC100151531	zinc finger protein Gfi-1b-like	0.017
eomesb	eomesodermin homolog b	0.017	Human Mouse
pdcd2	programmed cell death 2	0.017
cd74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.016
otx1b	orthodenticle homolog 1b	0.016
tshz1	teashirt family zinc finger 1	0.016
pax5	paired box gene 5	0.016
plcg1	phospholipase C, gamma 1	0.016
foxa1	forkhead box A1	0.016
si:dkey-27i16.2	si:dkey-27i16.2	0.016
scd	stearoyl-CoA desaturase (delta-9-desaturase)	0.015
zgc:91835	zgc:91835	0.015
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.015
LOC100003514	protein kinase C alpha type-like	0.015
lgals3l	lectin, galactoside-binding, soluble, 3 (galectin 3)-like	0.015
ptprc	protein tyrosine phosphatase, receptor type, C	0.014	Mouse
smoc2	secreted modular calcium binding protein 2	0.014
rpe65b	retinal pigment epithelium-specific protein 65b	0.014
dusp6	dual specificity phosphatase 6	0.014
runx2b	runt-related transcription factor 2b	0.014	Mouse
zgc:56039	zgc:56039	0.014
dlg2	discs, large (Drosophila) homolog 2	0.014
cbfb	core-binding factor, beta subunit	0.014
elk4	ELK4, ETS-domain protein	0.014
tgfb1a	transforming growth factor, beta 1a	0.013	Mouse
cd63	Cd63 antigen	0.013
egr1	early growth response 1	0.013	Mouse
ccr9b	chemokine (C-C motif) receptor 9b	0.013
baxa	bcl2-associated X protein, a	0.013	Mouse
twist2	twist2	0.013
myd88	myeloid differentiation primary response gene (88)	0.013
axin2	axin 2 (conductin, axil)	0.012
lyz	lysozyme	0.012
abcb5	ATP-binding cassette, sub-family B (MDR/TAP), member 5	0.012
wasa	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a	0.012	Mouse
entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.012
sdcbp	syndecan binding protein (syntenin)	0.012
rag2	recombination activating gene 2	0.011	Mouse
npm4	nucleophosmin/nucleoplasmin, 4	0.011
mibp2	muscle-specific beta 1 integrin binding protein 2	0.011
sh3gl1b	SH3-domain GRB2-like 1b	0.011
il4r	interleukin 4 receptor	0.011
LOC566708	FL cytokine receptor-like	0.011
csf1ra	colony stimulating factor 1 receptor, a	0.011
met	met proto-oncogene (hepatocyte growth factor receptor)	0.011
oprd1b	opioid receptor, delta 1b	0.011
zgc:56382	zgc:56382	0.011
pglyrp5	peptidoglycan recognition protein 5	0.011
bcl2	B-cell leukemia/lymphoma 2	0.010	Mouse
hspe1	heat shock 10 protein 1 (chaperonin 10)	0.010
col10a1	collagen, type X, alpha 1	0.010
ptk2.1	protein tyrosine kinase 2a	0.010
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.010	Mouse
pcdh18b	protocadherin 18b	0.010
calrl	calreticulin like	0.010
si:dkeyp-51c11.1	si:dkeyp-51c11.1	0.010