The network for 'developmental pigmentation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

developmental pigmentation

The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.

Drosophila melanogaster
Name Description Probability Func Analog Organism
y yellow 0.930
fw furrowed 0.823
trx trithorax 0.707
bw brown 0.586
nec necrotic 0.519
Arr2 Arrestin 2 0.519
W Wrinkled 0.518
ltd lightoid 0.510
ph-d polyhomeotic distal 0.505
oc ocelliless 0.498
ninaA neither inactivation nor afterpotential A 0.478
cn cinnabar 0.478
nkd naked cuticle 0.430
Smox Smad on X 0.417
N Notch 0.413
CG5958 CG5958 gene product from transcript CG5958-RA 0.407
rb ruby 0.398
luna CG33473 gene product from transcript CG33473-RB 0.384
Mob2 CG11711 gene product from transcript CG11711-RC 0.379
phyl phyllopod 0.375
Pink1 PTEN-induced putative kinase 1 0.372
rdgC retinal degeneration C 0.359
ninaE neither inactivation nor afterpotential E 0.356
kar karmoisin 0.350
jeb jelly belly 0.349
Psn Presenilin 0.344
Rab6 Rab-protein 6 0.330
jar jaguar 0.321
sd scalloped 0.304
sina seven in absentia 0.297
sno strawberry notch 0.297
Pka-C1 cAMP-dependent protein kinase 1 0.291
slou slouch 0.288
frc fringe connection 0.287
Tal CG2827 gene product from transcript CG2827-RA 0.280
e ebony 0.273
CG11147 CG11147 gene product from transcript CG11147-RA 0.270
v vermilion 0.265
inaD inactivation no afterpotential D 0.254
twi twist 0.250
Mad Mothers against dpp 0.247
rk rickets 0.242
CG11570 CG11570 gene product from transcript CG11570-RA 0.238
Rh5 Rhodopsin 5 0.230
trp transient receptor potential 0.220
CG11786 CG11786 gene product from transcript CG11786-RB 0.209
Hdac3 Histone deacetylase 3 0.205
Vps16A Vacuolar protein sorting 16A 0.195
Cyp301a1 CG8587 gene product from transcript CG8587-RA 0.192
CG14526 CG14526 gene product from transcript CG14526-RB 0.190
CG33970 CG33970 gene product from transcript CG33970-RA 0.187
nej nejire 0.185
Pu Punch 0.174
Apc APC-like 0.167
trpl trp-like 0.166
CG17919 CG17919 gene product from transcript CG17919-RA 0.163
ade2 adenosine 2 0.162
Parp Poly-(ADP-ribose) polymerase 0.161
gho ghost 0.159
CG9664 CG9664 gene product from transcript CG9664-RB 0.157
sev sevenless 0.155
CG9990 CG9990 gene product from transcript CG9990-RA 0.154
Rab30 CG9100 gene product from transcript CG9100-RB 0.151
prel preli-like 0.150
Pvf1 PDGF- and VEGF-related factor 1 0.146
ovo CG6824 gene product from transcript CG6824-RE 0.146
prd paired 0.145
slik Sterile20-like kinase 0.144
CG5973 CG5973 gene product from transcript CG5973-RA 0.144
CG31778 CG31778 gene product from transcript CG31778-RA 0.143
Gp150 CG5820 gene product from transcript CG5820-RA 0.141
Wnt4 Wnt oncogene analog 4 0.141
CG17278 CG17278 gene product from transcript CG17278-RA 0.138
Gga CG3002 gene product from transcript CG3002-RB 0.136
kkv krotzkopf verkehrt 0.135
PGRP-LE Peptidoglycan recognition protein LE 0.133
ort ora transientless 0.131
p53 CG33336 gene product from transcript CG33336-RB 0.128
CG10550 CG10550 gene product from transcript CG10550-RB 0.128
CG2254 CG2254 gene product from transcript CG2254-RA 0.128
Ack CG14992 gene product from transcript CG14992-RA 0.125
Act5C Actin 5C 0.125
alph alphabet 0.123
Cat Catalase 0.120
wb wing blister 0.119
pck pickel 0.117
Rsf1 Repressor splicing factor 1 0.116
CG42863 CG42863 gene product from transcript CG42863-RB 0.115
eys eyes shut 0.115
lt light 0.114
InR Insulin-like receptor 0.113
Gbeta76C G protein beta-subunit 76C 0.113
CG16733 CG16733 gene product from transcript CG16733-RA 0.111
kek5 kekkon5 0.110
ade5 CG3989 gene product from transcript CG3989-RA 0.109
Sulf1 Sulfated 0.107
CG12026 CG12026 gene product from transcript CG12026-RB 0.107
CG6776 CG6776 gene product from transcript CG6776-RA 0.107
CG5853 CG5853 gene product from transcript CG5853-RA 0.107
run runt 0.106
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
kita kit receptor a 1.000
sox10 SRY-box containing gene 10 1.000
mitfa microphthalmia-associated transcription factor a 0.999
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.999
tyr tyrosinase 0.999
zgc:112329 zgc:112329 0.997
vps39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.991
sc:d812 sc:d812 0.981
slc24a5 solute carrier family 24, member 5 0.970
pmela premelanosome protein a 0.965
mib mind bomb 0.960
ltk leukocyte tyrosine kinase 0.947
foxd3 forkhead box D3 0.943
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.924
sox2 SRY-box containing gene 2 0.921
slc45a2 solute carrier family 45, member 2 0.901
tfap2a transcription factor AP-2 alpha 0.899
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.848
crestin crestin 0.802
dct dopachrome tautomerase 0.791
csf1ra colony stimulating factor 1 receptor, a 0.764
kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 0.729
col2a1a collagen type II, alpha-1a 0.678
foxi1 forkhead box I1 0.623
fcho2 FCH domain only 2 0.611
prdm1a PR domain containing 1a, with ZNF domain 0.518
sox9a SRY-box containing gene 9a 0.508
pcdh18a protocadherin 18a 0.454
tfec transcription factor EC 0.428
igf1rb insulin-like growth factor 1b receptor 0.403
foxa3 forkhead box A3 0.365
mpp5a membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a) 0.326
tyrp1 tyrosinase-related protein 1 0.322
notch1a notch homolog 1a 0.321
rx3 retinal homeobox gene 3 0.320
mitfb microphthalmia-associated transcription factor b 0.309
ednrb1 endothelin receptor B 0.289
cx41.8 connexin 41.8 0.288
zic2b zic family member 2 (odd-paired homolog, Drosophila) b 0.288
sox19a SRY-box containing gene 19a 0.282
lef1 lymphocyte enhancer binding factor 1 0.278
crb2a crumbs homolog 2a 0.273
sox9b SRY-box containing gene 9b 0.272
efnb2a ephrin B2a 0.271
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.266
tfap2e transcription factor AP-2 epsilon 0.263
mecp2 methyl CpG binding protein 2 0.255
zgc:162420 zgc:162420 0.255
wt1a wilms tumor 1a 0.246
wu:fv91b12 wu:fv91b12 0.245
msxb muscle segment homeobox B 0.240
cdh5 cadherin 5 0.240
zgc:100919 zgc:100919 0.222
sox3 SRY-box containing gene 3 0.216
slc4a1b solute carrier family 4, anion exchanger, member 1b 0.208
zgc:162329 zgc:162329 0.205
sox7 SRY-box containing gene 7 0.200
tyrp1b tyrosinase-related protein 1b 0.196
ptk2.1 protein tyrosine kinase 2a 0.196
atp6v1f ATPase, H+ transporting, V1 subunit F 0.192
mlphb melanophilin b 0.192
gart phosphoribosylglycinamide formyltransferase 0.183
tbx2b T-box 2b 0.181
fn1 fibronectin 1 0.178
six4b sine oculis homeobox homolog 4b 0.172
pnp4a purine nucleoside phosphorylase 4a 0.159
plcb3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.156
otx1b orthodenticle homolog 1b 0.156
grhl1 grainyhead-like 1 (Drosophila) 0.150
nf1a neurofibromin 1a 0.146
ptch1 patched 1 0.144
notch3 notch homolog 3 0.132
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.131
egr2b early growth response 2b 0.129
slc4a4a solute carrier family 4, member 4a 0.129
shhb sonic hedgehog b 0.128
furina furin (paired basic amino acid cleaving enzyme) a 0.126
tfeb transcription factor EB 0.125
tp63 tumor protein p63 0.123
prdm5 PR domain containing 5 0.123
zgc:85942 zgc:85942 0.119
spra sepiapterin reductase a 0.119
jag1b jagged 1b 0.119
dll4 delta-like 4 (Drosophila) 0.117
foxc1a forkhead box C1a 0.116
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.116
paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.114
dacha dachshund a 0.111
phf21a PHD finger protein 21A 0.110
tshb thyroid stimulating hormone, beta subunit 0.104
cart1 cartilage paired-class homeoprotein 1 0.103
sox1a SRY-box containing gene 1a 0.103
meis2.1 myeloid ecotropic viral integration site 2.1 0.102
sf3b1 splicing factor 3b, subunit 1 0.100
nrg1 neuregulin 1 0.094
gdf6a growth differentiation factor 6a 0.093
atp7a ATPase, Cu++ transporting, alpha polypeptide 0.091
kctd15a potassium channel tetramerisation domain containing 15a 0.088
zic4 zic family member 4 0.086
stc1l stanniocalcin 1, like 0.086
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Homo sapiens
Name Description Probability Func Analog Organism
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 0.797
DTNBP1 dystrobrevin binding protein 1 0.726
PLDN pallidin homolog (mouse) 0.685
EP300 E1A binding protein p300 0.555
PAX3 paired box 3 0.519
BAK1 BCL2-antagonist/killer 1 0.223
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.212
POU5F1 POU class 5 homeobox 1 0.181
POU3F2 POU class 3 homeobox 2 0.160
PSEN1 presenilin 1 0.159
ARRB1 arrestin, beta 1 0.148
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 0.139
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.134
MEOX2 mesenchyme homeobox 2 0.133
SOX10 SRY (sex determining region Y)-box 10 0.122
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.100
MUTED muted homolog (mouse) 0.099
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.095
RAB27A RAB27A, member RAS oncogene family 0.082
SNAPIN SNAP-associated protein 0.082
BCL2L1 BCL2-like 1 0.068
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3 0.052
FYN FYN oncogene related to SRC, FGR, YES 0.046
MLPH melanophilin 0.045
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.042
PSEN2 presenilin 2 (Alzheimer disease 4) 0.032
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.032
BBS2 Bardet-Biedl syndrome 2 0.028
BIK BCL2-interacting killer (apoptosis-inducing) 0.027
AMBRA1 autophagy/beclin-1 regulator 1 0.026
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.026
RAB14 RAB14, member RAS oncogene family 0.025
BID BH3 interacting domain death agonist 0.024
EPS15 epidermal growth factor receptor pathway substrate 15 0.024
BECN1 beclin 1, autophagy related 0.023
CD9 CD9 molecule 0.021
NRIP1 nuclear receptor interacting protein 1 0.021
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.020
GSK3B glycogen synthase kinase 3 beta 0.020
TIMP1 TIMP metallopeptidase inhibitor 1 0.019
MTF1 metal-regulatory transcription factor 1 0.019
EXOC7 exocyst complex component 7 0.017
BAX BCL2-associated X protein 0.017
EPAS1 endothelial PAS domain protein 1 0.016
BAD BCL2-associated agonist of cell death 0.016
CTBP1 C-terminal binding protein 1 0.016
TTC8 tetratricopeptide repeat domain 8 0.015
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.015
TCF4 transcription factor 4 0.014
FLNB filamin B, beta 0.014
PDIA3 protein disulfide isomerase family A, member 3 0.014
LDOC1 leucine zipper, down-regulated in cancer 1 0.014
HDAC9 histone deacetylase 9 0.013
RNF144B ring finger protein 144B 0.013
BBC3 BCL2 binding component 3 0.012
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.012
RNR2 l-rRNA 0.012
PCM1 pericentriolar material 1 0.012
C19orf46 chromosome 19 open reading frame 46 0.011
AGFG1 ArfGAP with FG repeats 1 0.011
BBS1 Bardet-Biedl syndrome 1 0.011
TP53BP2 tumor protein p53 binding protein, 2 0.011
FKBP8 FK506 binding protein 8, 38kDa 0.011
GRB7 growth factor receptor-bound protein 7 0.011
APH1A anterior pharynx defective 1 homolog A (C. elegans) 0.010
EEF2K eukaryotic elongation factor-2 kinase 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Mitf microphthalmia-associated transcription factor 1.000
Lyst lysosomal trafficking regulator 1.000
a nonagouti 0.998
Pax3 paired box gene 3 0.994
Tyrp1 tyrosinase-related protein 1 0.992
Ednrb endothelin receptor type B 0.991
Tyr tyrosinase 0.991
Hps1 Hermansky-Pudlak syndrome 1 homolog (human) 0.977
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.973
Ap3b1 adaptor-related protein complex 3, beta 1 subunit 0.968
Vegfa vascular endothelial growth factor A 0.960
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.942
Trp53 transformation related protein 53 0.939
Rab27a RAB27A, member RAS oncogene family 0.912
Meox2 mesenchyme homeobox 2 0.911
Kit kit oncogene 0.908
Cno cappuccino 0.880
Gli2 GLI-Kruppel family member GLI2 0.867
Sox10 SRY-box containing gene 10 0.854
Ret ret proto-oncogene 0.851
Pitx2 paired-like homeodomain transcription factor 2 0.837
Oca2 oculocutaneous albinism II 0.788
Tgfb1 transforming growth factor, beta 1 0.768
Tcfap2a transcription factor AP-2, alpha 0.756
Hand1 heart and neural crest derivatives expressed transcript 1 0.745
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.697
Fgfr2 fibroblast growth factor receptor 2 0.629
Bax BCL2-associated X protein 0.617
Hps4 Hermansky-Pudlak syndrome 4 homolog (human) 0.603
Isl1 ISL1 transcription factor, LIM/homeodomain 0.598
Ap3d1 adaptor-related protein complex 3, delta 1 subunit 0.583
Pax6 paired box gene 6 0.559
Sox9 SRY-box containing gene 9 0.555
Mlph melanophilin 0.548
Prrx1 paired related homeobox 1 0.526
Pldn pallidin 0.509
Hps5 Hermansky-Pudlak syndrome 5 homolog (human) 0.492
Bcl2 B-cell leukemia/lymphoma 2 0.471
Hdac4 histone deacetylase 4 0.469
Fgf8 fibroblast growth factor 8 0.389
Fzd4 frizzled homolog 4 (Drosophila) 0.388
Gli3 GLI-Kruppel family member GLI3 0.355
Nf1 neurofibromatosis 1 0.354
Zeb1 zinc finger E-box binding homeobox 1 0.350
Acvr1 activin A receptor, type 1 0.302
Foxc1 forkhead box C1 0.297
Hand2 heart and neural crest derivatives expressed transcript 2 0.291
Flt1 FMS-like tyrosine kinase 1 0.275
Rarb retinoic acid receptor, beta 0.272
Usp8 ubiquitin specific peptidase 8 0.259
Pou5f1 POU domain, class 5, transcription factor 1 0.248
Sox2 SRY-box containing gene 2 0.246
Gdnf glial cell line derived neurotrophic factor 0.244
Bbs2 Bardet-Biedl syndrome 2 (human) 0.241
Pmel premelanosome protein 0.234
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.230
Nrp1 neuropilin 1 0.225
Hps6 Hermansky-Pudlak syndrome 6 0.224
Cbl Casitas B-lineage lymphoma 0.224
Foxc2 forkhead box C2 0.216
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.214
Cdh11 cadherin 11 0.200
Fgfr3 fibroblast growth factor receptor 3 0.198
Ednra endothelin receptor type A 0.196
Adamts20 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20 0.195
Insm1 insulinoma-associated 1 0.193
Muted muted 0.191
Nr0b1 nuclear receptor subfamily 0, group B, member 1 0.182
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.182
Smo smoothened homolog (Drosophila) 0.180
Foxi3 forkhead box I3 0.177
Bmp4 bone morphogenetic protein 4 0.169
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.163
Hdac7 histone deacetylase 7 0.162
Nanog Nanog homeobox 0.154
Fgfr1 fibroblast growth factor receptor 1 0.154
Igf2r insulin-like growth factor 2 receptor 0.135
Ncstn nicastrin 0.131
Pdgfb platelet derived growth factor, B polypeptide 0.128
Tgfb2 transforming growth factor, beta 2 0.128
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.124
Pcp2 Purkinje cell protein 2 (L7) 0.115
Ebf3 early B-cell factor 3 0.113
Cd2ap CD2-associated protein 0.108
Sharpin SHANK-associated RH domain interacting protein 0.106
Adamts9 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9 0.104
Sall4 sal-like 4 (Drosophila) 0.097
Npr3 natriuretic peptide receptor 3 0.096
Pkd1 polycystic kidney disease 1 homolog 0.095
Runx2 runt related transcription factor 2 0.093
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.087
Ap1g1 adaptor protein complex AP-1, gamma 1 subunit 0.085
Ren1 renin 1 structural 0.085
Cdh5 cadherin 5 0.085
Cenpj centromere protein J 0.082
Hdac5 histone deacetylase 5 0.079
Myo5a myosin VA 0.078
Alx4 aristaless-like homeobox 4 0.078
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.077
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.077
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism