The network for 'regulation of granzyme b production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of granzyme b production

Any process that modulates the frequency, rate, or extent of production of granzyme B.

Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 1.000
IL8 interleukin 8 0.989
IL6 interleukin 6 (interferon, beta 2) 0.950
CCL2 chemokine (C-C motif) ligand 2 0.943
IL1B interleukin 1, beta 0.928
CCL4 chemokine (C-C motif) ligand 4 0.923
CXCL2 chemokine (C-X-C motif) ligand 2 0.908
CXCL10 chemokine (C-X-C motif) ligand 10 0.850
CCL8 chemokine (C-C motif) ligand 8 0.844
CXCL3 chemokine (C-X-C motif) ligand 3 0.811
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.801
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.744
IDE insulin-degrading enzyme 0.708
CXCL9 chemokine (C-X-C motif) ligand 9 0.695
CCL13 chemokine (C-C motif) ligand 13 0.566
CCL20 chemokine (C-C motif) ligand 20 0.533
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.506
DPP4 dipeptidyl-peptidase 4 0.499
ICAM1 intercellular adhesion molecule 1 0.329
CCL22 chemokine (C-C motif) ligand 22 0.267
CD83 CD83 molecule 0.264
CXCL5 chemokine (C-X-C motif) ligand 5 0.198
CCL7 chemokine (C-C motif) ligand 7 0.196
CCL19 chemokine (C-C motif) ligand 19 0.180
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.173
RGS1 regulator of G-protein signaling 1 0.159
SELE selectin E 0.142
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.140
CXCL13 chemokine (C-X-C motif) ligand 13 0.122
CCR4 chemokine (C-C motif) receptor 4 0.108
VCAM1 vascular cell adhesion molecule 1 0.108
CH25H cholesterol 25-hydroxylase 0.107
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.103
CCL5 chemokine (C-C motif) ligand 5 0.098
CXCL11 chemokine (C-X-C motif) ligand 11 0.095
TRAF1 TNF receptor-associated factor 1 0.095
CCL3 chemokine (C-C motif) ligand 3 0.093
TNF tumor necrosis factor 0.084
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.077
CCR7 chemokine (C-C motif) receptor 7 0.070
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.070
CCR1 chemokine (C-C motif) receptor 1 0.068
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.065
IL1RN interleukin 1 receptor antagonist 0.065
IL10 interleukin 10 0.064
DARC Duffy blood group, chemokine receptor 0.063
CCL11 chemokine (C-C motif) ligand 11 0.060
BIRC3 baculoviral IAP repeat containing 3 0.050
IFNG interferon, gamma 0.047
BCL2A1 BCL2-related protein A1 0.045
IL7R interleukin 7 receptor 0.042
ARRB1 arrestin, beta 1 0.036
CD40 CD40 molecule, TNF receptor superfamily member 5 0.036
INHBA inhibin, beta A 0.036
SOD2 superoxide dismutase 2, mitochondrial 0.035
UBD ubiquitin D 0.034
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.031
CCL21 chemokine (C-C motif) ligand 21 0.030
OSMR oncostatin M receptor 0.030
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.030
IL1A interleukin 1, alpha 0.029
IL1R2 interleukin 1 receptor, type II 0.029
CCL3L3 chemokine (C-C motif) ligand 3-like 3 0.028
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.027
GNLY granulysin 0.027
FPR3 formyl peptide receptor 3 0.026
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.025
MSC musculin 0.025
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 0.025
IL32 interleukin 32 0.025
ADAMDEC1 ADAM-like, decysin 1 0.024
CD69 CD69 molecule 0.024
EBI3 Epstein-Barr virus induced 3 0.024
RGS16 regulator of G-protein signaling 16 0.023
SRGN serglycin 0.023
PLEK pleckstrin 0.022
SLAMF8 SLAM family member 8 0.022
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.021
MMP10 matrix metallopeptidase 10 (stromelysin 2) 0.021
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.020
CSF1 colony stimulating factor 1 (macrophage) 0.019
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.019
C1QA complement component 1, q subcomponent, A chain 0.019
IL2RB interleukin 2 receptor, beta 0.019
CXCL12 chemokine (C-X-C motif) ligand 12 0.019
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.019
STAT4 signal transducer and activator of transcription 4 0.018
CCL17 chemokine (C-C motif) ligand 17 0.018
GPR109B G protein-coupled receptor 109B 0.018
LIF leukemia inhibitory factor (cholinergic differentiation factor) 0.017
XCL1 chemokine (C motif) ligand 1 0.017
PI3 peptidase inhibitor 3, skin-derived 0.016
CCL1 chemokine (C-C motif) ligand 1 0.016
CCL23 chemokine (C-C motif) ligand 23 0.015
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.015
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.015
APOC1 apolipoprotein C-I 0.015
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.014
CCR3 chemokine (C-C motif) receptor 3 0.013
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.013
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism