IMP
Process View
The network for 'chemokine c c motif ligand 21 signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
chemokine c c motif ligand 21 signaling pathway
A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CCL5 | chemokine (C-C motif) ligand 5 | 1.000 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 1.000 | |
| IL2RB | interleukin 2 receptor, beta | 0.996 | |
| IFNG | interferon, gamma | 0.993 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.991 | |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.982 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.977 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.963 | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.938 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.921 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.909 | |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.901 | |
| IRF4 | interferon regulatory factor 4 | 0.880 | |
| CD40LG | CD40 ligand | 0.877 | |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.836 | |
| CLEC7A | C-type lectin domain family 7, member A | 0.830 | |
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.829 | |
| IL16 | interleukin 16 (lymphocyte chemoattractant factor) | 0.821 | |
| SLAMF7 | SLAM family member 7 | 0.772 | |
| IL10RA | interleukin 10 receptor, alpha | 0.684 | |
| CCR6 | chemokine (C-C motif) receptor 6 | 0.641 | |
| GPR171 | G protein-coupled receptor 171 | 0.617 | |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.610 | |
| IL10 | interleukin 10 | 0.539 | |
| CD2 | CD2 molecule | 0.493 | |
| CCL3 | chemokine (C-C motif) ligand 3 | 0.477 | |
| CYBB | cytochrome b-245, beta polypeptide | 0.472 | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.439 | |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.423 | |
| SELL | selectin L | 0.386 | |
| IL2RG | interleukin 2 receptor, gamma | 0.371 | |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | 0.338 | |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.308 | |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.296 | |
| CD48 | CD48 molecule | 0.289 | |
| CCR8 | chemokine (C-C motif) receptor 8 | 0.263 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.262 | |
| ITK | IL2-inducible T-cell kinase | 0.252 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.250 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.249 | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.229 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.221 | |
| CLEC4A | C-type lectin domain family 4, member A | 0.206 | |
| CD163 | CD163 molecule | 0.201 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.200 | |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.198 | |
| TNF | tumor necrosis factor | 0.193 | |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | 0.181 | |
| CCL7 | chemokine (C-C motif) ligand 7 | 0.172 | |
| IL1B | interleukin 1, beta | 0.155 | |
| CD86 | CD86 molecule | 0.155 | |
| IL21R | interleukin 21 receptor | 0.149 | |
| BIN2 | bridging integrator 2 | 0.148 | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.142 | |
| GPR18 | G protein-coupled receptor 18 | 0.120 | |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.113 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.107 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.106 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.100 | |
| CCR9 | chemokine (C-C motif) receptor 9 | 0.098 | |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.095 | |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.090 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.087 | |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.078 | |
| IL1R2 | interleukin 1 receptor, type II | 0.075 | |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.074 | |
| IL1F5 | interleukin 1 family, member 5 (delta) | 0.071 | |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.067 | |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.061 | |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.060 | |
| RGS1 | regulator of G-protein signaling 1 | 0.059 | |
| SASH3 | SAM and SH3 domain containing 3 | 0.058 | |
| LAG3 | lymphocyte-activation gene 3 | 0.058 | |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.056 | |
| IL8 | interleukin 8 | 0.055 | |
| RUNX3 | runt-related transcription factor 3 | 0.055 | |
| CD83 | CD83 molecule | 0.053 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.052 | |
| CD69 | CD69 molecule | 0.050 | |
| IL7R | interleukin 7 receptor | 0.046 | |
| IL2RA | interleukin 2 receptor, alpha | 0.043 | |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.042 | |
| GPR109B | G protein-coupled receptor 109B | 0.042 | |
| TAGAP | T-cell activation RhoGTPase activating protein | 0.040 | |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | 0.039 | |
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.038 | |
| MSR1 | macrophage scavenger receptor 1 | 0.037 | |
| TBX21 | T-box 21 | 0.037 | |
| C3AR1 | complement component 3a receptor 1 | 0.037 | |
| CD1C | CD1c molecule | 0.036 | |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.035 | |
| AQP9 | aquaporin 9 | 0.034 | |
| CYTIP | cytohesin 1 interacting protein | 0.033 | |
| SLAMF6 | SLAM family member 6 | 0.032 | |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.032 | |
| CXCR1 | chemokine (C-X-C motif) receptor 1 | 0.032 | |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.031 | |
| IRF8 | interferon regulatory factor 8 | 0.031 | |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.031 | |
| UBASH3A | ubiquitin associated and SH3 domain containing A | 0.031 |
