The network for 'positive regulation of t cell chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of t cell chemotaxis

Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.

Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 0.999
CXCL9 chemokine (C-X-C motif) ligand 9 0.978
ABI2 abl-interactor 2 0.886
CCL4 chemokine (C-C motif) ligand 4 0.733
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.698
CXCL10 chemokine (C-X-C motif) ligand 10 0.664
CCL13 chemokine (C-C motif) ligand 13 0.540
DLG1 discs, large homolog 1 (Drosophila) 0.446
CCL22 chemokine (C-C motif) ligand 22 0.385
CXCL11 chemokine (C-X-C motif) ligand 11 0.356
DPP4 dipeptidyl-peptidase 4 0.302
IL8 interleukin 8 0.301
CCL19 chemokine (C-C motif) ligand 19 0.286
CCR7 chemokine (C-C motif) receptor 7 0.270
CCL8 chemokine (C-C motif) ligand 8 0.236
CXCL13 chemokine (C-X-C motif) ligand 13 0.181
SH3D19 SH3 domain containing 19 0.177
IFNG interferon, gamma 0.174
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.170
CCL5 chemokine (C-C motif) ligand 5 0.156
SNX33 sorting nexin 33 0.146
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.140
CXCL3 chemokine (C-X-C motif) ligand 3 0.131
IL1B interleukin 1, beta 0.129
CCR1 chemokine (C-C motif) receptor 1 0.128
CXCL2 chemokine (C-X-C motif) ligand 2 0.122
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.118
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.114
CXCR6 chemokine (C-X-C motif) receptor 6 0.103
PDIA3 protein disulfide isomerase family A, member 3 0.100
CCL11 chemokine (C-C motif) ligand 11 0.091
IL6 interleukin 6 (interferon, beta 2) 0.083
IDE insulin-degrading enzyme 0.079
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.073
IL10 interleukin 10 0.071
CCR4 chemokine (C-C motif) receptor 4 0.062
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.062
SH3PXD2A SH3 and PX domains 2A 0.059
UBD ubiquitin D 0.055
CCL2 chemokine (C-C motif) ligand 2 0.054
IL2RB interleukin 2 receptor, beta 0.047
FPR3 formyl peptide receptor 3 0.042
CXCL5 chemokine (C-X-C motif) ligand 5 0.041
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.040
ADAMDEC1 ADAM-like, decysin 1 0.038
FZD1 frizzled homolog 1 (Drosophila) 0.035
CCL20 chemokine (C-C motif) ligand 20 0.034
CD83 CD83 molecule 0.034
RGS1 regulator of G-protein signaling 1 0.030
IL7R interleukin 7 receptor 0.030
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.029
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.029
CCL7 chemokine (C-C motif) ligand 7 0.026
CPD carboxypeptidase D 0.025
CD80 CD80 molecule 0.024
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.023
VCAM1 vascular cell adhesion molecule 1 0.023
TNF tumor necrosis factor 0.023
SELE selectin E 0.022
BCL2A1 BCL2-related protein A1 0.021
SLAMF8 SLAM family member 8 0.021
SLAMF7 SLAM family member 7 0.021
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.020
LAMP3 lysosomal-associated membrane protein 3 0.020
CH25H cholesterol 25-hydroxylase 0.019
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.018
CXCR3 chemokine (C-X-C motif) receptor 3 0.017
IRF4 interferon regulatory factor 4 0.016
SPRR2A small proline-rich protein 2A 0.014
CCL17 chemokine (C-C motif) ligand 17 0.013
CD84 CD84 molecule 0.013
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.012
CCL3 chemokine (C-C motif) ligand 3 0.012
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.010
CCL21 chemokine (C-C motif) ligand 21 0.010
IL2RG interleukin 2 receptor, gamma 0.010
FASLG Fas ligand (TNF superfamily, member 6) 0.010
ADAM9 ADAM metallopeptidase domain 9 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ccl2 chemokine (C-C motif) ligand 2 0.764
Ifng interferon gamma 0.665
Ccl3 chemokine (C-C motif) ligand 3 0.466
Ccr2 chemokine (C-C motif) receptor 2 0.388
Ccr1 chemokine (C-C motif) receptor 1 0.302
Cxcl13 chemokine (C-X-C motif) ligand 13 0.143
Lta lymphotoxin A 0.115
Ltb lymphotoxin B 0.113
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.113
Ccl8 chemokine (C-C motif) ligand 8 0.111
Cd44 CD44 antigen 0.087
Il1b interleukin 1 beta 0.087
Ccl4 chemokine (C-C motif) ligand 4 0.086
Ccr5 chemokine (C-C motif) receptor 5 0.080
Tnf tumor necrosis factor 0.077
C3ar1 complement component 3a receptor 1 0.071
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.065
Gzmk granzyme K 0.057
Cxcr5 chemokine (C-X-C motif) receptor 5 0.038
Ccl7 chemokine (C-C motif) ligand 7 0.033
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.033
Cd7 CD7 antigen 0.033
Folr2 folate receptor 2 (fetal) 0.030
Ctsw cathepsin W 0.028
Gzmb granzyme B 0.028
Itgax integrin alpha X 0.028
Irg1 immunoresponsive gene 1 0.025
Selp selectin, platelet 0.025
Il1rn interleukin 1 receptor antagonist 0.023
Pdcd1 programmed cell death 1 0.022
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.022
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.021
Mmp12 matrix metallopeptidase 12 0.021
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.021
Cd96 CD96 antigen 0.021
Ubd ubiquitin D 0.020
Icos inducible T-cell co-stimulator 0.020
Cxcr3 chemokine (C-X-C motif) receptor 3 0.020
Fcgr1 Fc receptor, IgG, high affinity I 0.020
Ccl12 chemokine (C-C motif) ligand 12 0.019
Xcr1 chemokine (C motif) receptor 1 0.018
Cd40 CD40 antigen 0.018
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.017
Ch25h cholesterol 25-hydroxylase 0.017
Sh2d2a SH2 domain protein 2A 0.017
Batf basic leucine zipper transcription factor, ATF-like 0.016
Il12rb2 interleukin 12 receptor, beta 2 0.015
Ptgir prostaglandin I receptor (IP) 0.015
Gzma granzyme A 0.015
Nkg7 natural killer cell group 7 sequence 0.015
Ctla4 cytotoxic T-lymphocyte-associated protein 4 0.015
Gpr132 G protein-coupled receptor 132 0.014
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.013
Mmp3 matrix metallopeptidase 3 0.012
Cxcl9 chemokine (C-X-C motif) ligand 9 0.012
Bdkrb1 bradykinin receptor, beta 1 0.012
Cd3e CD3 antigen, epsilon polypeptide 0.012
Fasl Fas ligand (TNF superfamily, member 6) 0.011
Cd3d CD3 antigen, delta polypeptide 0.011
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.011
Dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.011
Ccl22 chemokine (C-C motif) ligand 22 0.011
Prdm1 PR domain containing 1, with ZNF domain 0.011
Ccl17 chemokine (C-C motif) ligand 17 0.010
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.010
Tlr2 toll-like receptor 2 0.010
Cxcl2 chemokine (C-X-C motif) ligand 2 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Cd14 CD14 molecule 0.510
Il1b interleukin 1 beta 0.472
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.259
Ccl4 chemokine (C-C motif) ligand 4 0.254
Ccl3 chemokine (C-C motif) ligand 3 0.223
Ccl2 chemokine (C-C motif) ligand 2 0.192
Serpinb2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.145
Il1r2 interleukin 1 receptor, type II 0.087
Cxcl10 chemokine (C-X-C motif) ligand 10 0.078
Cxcl2 chemokine (C-X-C motif) ligand 2 0.076
Prf1 perforin 1 (pore forming protein) 0.074
Reg3b regenerating islet-derived 3 beta 0.069
Mmp3 matrix metallopeptidase 3 0.069
Il6 interleukin 6 0.067
Tcf12 transcription factor 12 0.061
Dnase1l3 deoxyribonuclease 1-like 3 0.054
Calcrl calcitonin receptor-like 0.053
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.046
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.039
Nox4 NADPH oxidase 4 0.034
Igsf6 immunoglobulin superfamily, member 6 0.030
Rgs1 regulator of G-protein signaling 1 0.030
Mmp12 matrix metallopeptidase 12 0.030
Stx11 syntaxin 11 0.029
Cst7 cystatin F (leukocystatin) 0.027
Fcer1a Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.023
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.022
Klrc2 killer cell lectin-like receptor subfamily C, member 2 0.021
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.020
Gzmk granzyme K 0.020
Casp1 caspase 1 0.019
Fcgr2a Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.019
Mgst2 microsomal glutathione S-transferase 2 0.019
Nkg7 natural killer cell group 7 sequence 0.019
Clic4 chloride intracellular channel 4 0.018
Cd8a CD8a molecule 0.018
Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) 0.017
Ch25h cholesterol 25-hydroxylase 0.016
Xiap X-linked inhibitor of apoptosis 0.016
Egr2 early growth response 2 0.016
Cd247 Cd247 molecule 0.015
Upk3bl uroplakin 3B-like 0.015
Ccl7 chemokine (C-C motif) ligand 7 0.015
Fcn1 ficolin (collagen/fibrinogen domain containing) 1 0.014
Steap1 six transmembrane epithelial antigen of the prostate 1 0.014
Fosl1 fos-like antigen 1 0.014
Spink1 serine peptidase inhibitor, Kazal type 1 0.014
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.014
Prkacb protein kinase, cAMP dependent, catalytic, beta 0.014
Ccl11 chemokine (C-C motif) ligand 11 0.014
Reg3g regenerating islet-derived 3 gamma 0.013
Lect1 leukocyte cell derived chemotaxin 1 0.013
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.013
Plau plasminogen activator, urokinase 0.013
LOC689770 similar to osteoclast inhibitory lectin 0.013
Ccl20 chemokine (C-C motif) ligand 20 0.013
Fas Fas (TNF receptor superfamily, member 6) 0.013
Tfpi2 tissue factor pathway inhibitor 2 0.013
Btk Bruton agammaglobulinemia tyrosine kinase 0.013
Jak1 Janus kinase 1 0.012
Has2 hyaluronan synthase 2 0.012
Folr2 folate receptor 2 (fetal) 0.012
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.012
Sell selectin L 0.011
Sele selectin E 0.011
Gzmb granzyme B 0.011
Lin7c lin-7 homolog C (C. elegans) 0.011
Thbd thrombomodulin 0.011
Tlr2 toll-like receptor 2 0.011
Capn13 calpain 13 0.010
Soat1 sterol O-acyltransferase 1 0.010
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.010
Gzma granzyme A 0.010
Lrrc17 leucine rich repeat containing 17 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism