The network for 'response to testosterone' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to testosterone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.

Rattus norvegicus
Name Description Probability Func Analog Organism
Cyp51 cytochrome P450, family 51 0.477
Pdia4 protein disulfide isomerase family A, member 4 0.246
Azgp1 alpha-2-glycoprotein 1, zinc-binding 0.218
Lim2 lens intrinsic membrane protein 2 0.141
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.139
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.115
Slco1a4 solute carrier organic anion transporter family, member 1a4 0.110
Vcsa1 variable coding sequence A1 0.107
Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 0.104
Galnt5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) 0.102
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.100
Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 0.095
S1pr2 sphingosine-1-phosphate receptor 2 0.095
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.092
LOC100361864 UDP-glucuronosyltransferase 2B3-like 0.092
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.089
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.083
Hsp90b1 heat shock protein 90, beta, member 1 0.081
Sc4mol sterol-C4-methyl oxidase-like 0.077
LOC494499 LOC494499 protein 0.074
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.074
Acat3 acetyl-Coenzyme A acetyltransferase 3 0.073
Nat1 N-acetyltransferase 1 0.071
Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 0.071
Slc22a7 solute carrier family 22 (organic anion transporter), member 7 0.070
Rxrg retinoid X receptor gamma 0.069
Chia chitinase, acidic 0.067
Ube2d4 ubiquitin-conjugating enzyme E2D 4 0.067
Idi1 isopentenyl-diphosphate delta isomerase 1 0.065
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.063
Fgb fibrinogen beta chain 0.062
Sqle squalene epoxidase 0.061
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 0.061
Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 0.059
Fgf16 fibroblast growth factor 16 0.058
Gpr182 G protein-coupled receptor 182 0.058
Sult2al1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1 0.058
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.057
Sbp spermine binding protein 0.056
Zfp37 zinc finger protein 37 0.055
Grm5 glutamate receptor, metabotropic 5 0.054
Cdk2 cyclin dependent kinase 2 0.053
Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 0.052
Gsta5 glutathione S-transferase Yc2 subunit 0.052
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.052
Pik3c2g phosphoinositide-3-kinase, class 2, gamma polypeptide 0.052
Hyou1 hypoxia up-regulated 1 0.050
Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 0.050
St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.050
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.048
Mag myelin-associated glycoprotein 0.047
Scn5a sodium channel, voltage-gated, type V, alpha subunit 0.046
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.046
Notch3 Notch homolog 3 (Drosophila) 0.046
Gcm1 glial cells missing homolog 1 (Drosophila) 0.045
RGD1565859 RGD1565859 0.045
LOC100362601 PBPC1BS-like 0.044
Mbl2 mannose-binding lectin (protein C) 2 0.044
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.044
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.043
Gstm2 glutathione S-transferase mu 2 0.043
Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 0.042
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.042
Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.042
Rag1 recombination activating gene 1 0.041
Gjb1 gap junction protein, beta 1 0.041
Dlg4 discs, large homolog 4 (Drosophila) 0.041
Npy5r neuropeptide Y receptor Y5 0.041
Junb jun B proto-oncogene 0.041
Crx cone-rod homeobox 0.041
Barhl2 BarH-like homeobox 2 0.040
Rgs8 regulator of G-protein signaling 8 0.040
Gkn1 gastrokine 1 0.040
Ptger3 prostaglandin E receptor 3 (subtype EP3) 0.040
Apoa2 apolipoprotein A-II 0.038
Olr1641 olfactory receptor 1641 0.038
Cckar cholecystokinin A receptor 0.038
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.038
Trhr2 thyrotropin releasing hormone receptor 2 0.038
Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor 0.037
Ugt2b37 UDP-glucuronosyltransferase 2 family, member 37 0.037
Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 0.037
Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 0.037
Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 0.037
Lepr leptin receptor 0.037
Akr1c14 aldo-keto reductase family 1, member C14 0.036
Tpo thyroid peroxidase 0.036
RT1-M5 RT1 class Ib, locus M5 0.036
Sult1a1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.036
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.036
Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.036
Pigr polymeric immunoglobulin receptor 0.036
Fdft1 farnesyl diphosphate farnesyl transferase 1 0.036
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.036
Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.036
Nat8 N-acetyltransferase 8 0.035
Myo1b myosin Ib 0.035
Crygf crystallin, gamma F 0.035
Sert1 Sertoli cell protein 1 0.035
Prkg2 protein kinase, cGMP-dependent, type II 0.035
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
IRS1 insulin receptor substrate 1 0.362
IRS2 insulin receptor substrate 2 0.269
MAPK3 mitogen-activated protein kinase 3 0.178
MAPK14 mitogen-activated protein kinase 14 0.151
GRB2 growth factor receptor-bound protein 2 0.150
PLCG1 phospholipase C, gamma 1 0.127
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.123
EGFR epidermal growth factor receptor 0.115
SPDEF SAM pointed domain containing ets transcription factor 0.059
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.055
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.047
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.046
PPP5C protein phosphatase 5, catalytic subunit 0.045
PTPRJ protein tyrosine phosphatase, receptor type, J 0.043
KAT2B K(lysine) acetyltransferase 2B 0.042
MAPK1 mitogen-activated protein kinase 1 0.041
MAPK8 mitogen-activated protein kinase 8 0.040
MYLK2 myosin light chain kinase 2 0.039
SIRT1 sirtuin 1 0.037
ATF3 activating transcription factor 3 0.035
GAB2 GRB2-associated binding protein 2 0.035
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.034
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.032
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.030
EED embryonic ectoderm development 0.030
SH3BP2 SH3-domain binding protein 2 0.028
ARRDC3 arrestin domain containing 3 0.027
IGF1R insulin-like growth factor 1 receptor 0.027
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.027
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.027
GRB10 growth factor receptor-bound protein 10 0.026
DUSP3 dual specificity phosphatase 3 0.026
PTEN phosphatase and tensin homolog 0.025
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.025
JUN jun proto-oncogene 0.025
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.025
MAP2K1 mitogen-activated protein kinase kinase 1 0.025
PDIA3 protein disulfide isomerase family A, member 3 0.025
GAB1 GRB2-associated binding protein 1 0.025
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.024
C2orf18 chromosome 2 open reading frame 18 0.024
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.023
CDK6 cyclin-dependent kinase 6 0.023
BLNK B-cell linker 0.023
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.022
JUNB jun B proto-oncogene 0.021
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 0.021
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.021
LAT linker for activation of T cells 0.019
CCND1 cyclin D1 0.019
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.018
SUZ12 suppressor of zeste 12 homolog (Drosophila) 0.018
GRAP2 GRB2-related adaptor protein 2 0.018
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.017
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.017
CCNA1 cyclin A1 0.017
DDR2 discoidin domain receptor tyrosine kinase 2 0.017
FOS FBJ murine osteosarcoma viral oncogene homolog 0.016
STAT5A signal transducer and activator of transcription 5A 0.016
PDIA4 protein disulfide isomerase family A, member 4 0.016
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.016
COASY CoA synthase 0.016
PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.016
PTPRR protein tyrosine phosphatase, receptor type, R 0.016
APP amyloid beta (A4) precursor protein 0.016
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.016
EP300 E1A binding protein p300 0.016
PIK3CB phosphoinositide-3-kinase, catalytic, beta polypeptide 0.015
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.015
CMIP c-Maf-inducing protein 0.015
KLF6 Kruppel-like factor 6 0.015
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.015
RICTOR RPTOR independent companion of MTOR, complex 2 0.014
VAV3 vav 3 guanine nucleotide exchange factor 0.014
PDK1 pyruvate dehydrogenase kinase, isozyme 1 0.014
ZFYVE9 zinc finger, FYVE domain containing 9 0.014
HIPK2 homeodomain interacting protein kinase 2 0.014
P4HB prolyl 4-hydroxylase, beta polypeptide 0.014
NUCB2 nucleobindin 2 0.014
PEA15 phosphoprotein enriched in astrocytes 15 0.014
DUSP7 dual specificity phosphatase 7 0.013
TLR3 toll-like receptor 3 0.013
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.013
FZD1 frizzled homolog 1 (Drosophila) 0.013
NRIP1 nuclear receptor interacting protein 1 0.013
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.013
MUC1 mucin 1, cell surface associated 0.012
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.012
RHOB ras homolog gene family, member B 0.012
CYR61 cysteine-rich, angiogenic inducer, 61 0.012
EZR ezrin 0.012
CCND3 cyclin D3 0.012
TRIM27 tripartite motif containing 27 0.012
MAPT microtubule-associated protein tau 0.012
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.011
ARAF v-raf murine sarcoma 3611 viral oncogene homolog 0.011
KLF4 Kruppel-like factor 4 (gut) 0.011
PTPN21 protein tyrosine phosphatase, non-receptor type 21 0.011
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.011
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Bglap bone gamma carboxyglutamate protein 0.999
Lep leptin 0.998
LOC100048884 novel member of the major urinary protein (Mup) gene family 0.993
Fgfr2 fibroblast growth factor receptor 2 0.987
Mup10 major urinary protein 10 0.985
Mup19 major urinary protein 19 0.985
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.978
Mup5 major urinary protein 5 0.973
Ar androgen receptor 0.970
Mup9 major urinary protein 9 0.945
Ghr growth hormone receptor 0.943
Mup1 major urinary protein 1 0.935
Mup4 major urinary protein 4 0.930
Mup12 major urinary protein 12 0.926
Cav1 caveolin 1, caveolae protein 0.893
ND6 NADH dehydrogenase subunit 6 0.876
Lepr leptin receptor 0.872
Mup14 major urinary protein 14 0.861
Dlx2 distal-less homeobox 2 0.835
Mup3 major urinary protein 3 0.809
Mup7 major urinary protein 7 0.771
Mup17 major urinary protein 17 0.763
Mup13 major urinary protein 13 0.755
Mup11 major urinary protein 11 0.745
Kiss1 KiSS-1 metastasis-suppressor 0.744
Prlr prolactin receptor 0.721
LOC100048885 major urinary protein LOC100048885 0.698
Esr1 estrogen receptor 1 (alpha) 0.686
Irs2 insulin receptor substrate 2 0.677
Mup8 major urinary protein 8 0.646
Trp53 transformation related protein 53 0.634
Cdk6 cyclin-dependent kinase 6 0.634
Mup2 major urinary protein 2 0.632
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.625
Cdk4 cyclin-dependent kinase 4 0.605
Akr1c6 aldo-keto reductase family 1, member C6 0.572
Wfikkn2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.558
Mup15 major urinary protein 15 0.557
Irs1 insulin receptor substrate 1 0.521
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.511
Pparg peroxisome proliferator activated receptor gamma 0.506
Apc adenomatosis polyposis coli 0.487
Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.477
Fshr follicle stimulating hormone receptor 0.470
Gli3 GLI-Kruppel family member GLI3 0.426
Adh1 alcohol dehydrogenase 1 (class I) 0.421
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.418
Keg1 kidney expressed gene 1 0.364
Sva seminal vesicle antigen 0.345
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.344
Nos1 nitric oxide synthase 1, neuronal 0.336
Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 0.335
Ccnd1 cyclin D1 0.333
Kl klotho 0.333
Plin1 perilipin 1 0.321
Tyr tyrosinase 0.317
Vdr vitamin D receptor 0.278
Ep300 E1A binding protein p300 0.278
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.269
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.261
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.252
Cfhr2 complement factor H-related 2 0.252
Cfh complement component factor h 0.241
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.233
Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 0.201
Dlx5 distal-less homeobox 5 0.200
Slco1b2 solute carrier organic anion transporter family, member 1b2 0.192
Drd2 dopamine receptor D2 0.176
Slco1a1 solute carrier organic anion transporter family, member 1a1 0.176
Tdo2 tryptophan 2,3-dioxygenase 0.171
Msx1 homeobox, msh-like 1 0.167
Otc ornithine transcarbamylase 0.166
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.165
Adipoq adiponectin, C1Q and collagen domain containing 0.163
Npy5r neuropeptide Y receptor Y5 0.161
Foxf2 forkhead box F2 0.159
Inmt indolethylamine N-methyltransferase 0.156
Crp C-reactive protein, pentraxin-related 0.151
Pten phosphatase and tensin homolog 0.150
Ces3a carboxylesterase 3A 0.150
Sox9 SRY-box containing gene 9 0.147
Svs5 seminal vesicle secretory protein 5 0.146
Grb10 growth factor receptor bound protein 10 0.145
Tek endothelial-specific receptor tyrosine kinase 0.145
Zeb1 zinc finger E-box binding homeobox 1 0.141
Tgfb2 transforming growth factor, beta 2 0.133
Trim55 tripartite motif-containing 55 0.128
Ctnnb1 catenin (cadherin associated protein), beta 1 0.125
Pnpla2 patatin-like phospholipase domain containing 2 0.124
Adrb3 adrenergic receptor, beta 3 0.124
Gdf11 growth differentiation factor 11 0.122
Trp63 transformation related protein 63 0.118
Mvd mevalonate (diphospho) decarboxylase 0.115
Bmp2 bone morphogenetic protein 2 0.114
Cfhr1 complement factor H-related 1 0.113
Rb1 retinoblastoma 1 0.113
Kit kit oncogene 0.111
Inhba inhibin beta-A 0.109
Obp1a odorant binding protein Ia 0.108
Mup6 major urinary protein 6 0.106
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism