The network for 'positive regulation of multicellular organismal process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of multicellular organismal process

Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.

Rattus norvegicus
Name Description Probability Func Analog Organism
Icam1 intercellular adhesion molecule 1 0.881
Ccr5 chemokine (C-C motif) receptor 5 0.870
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.847
Cd37 CD37 molecule 0.837
RT1-Ba RT1 class II, locus Ba 0.804
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.787
Cd80 Cd80 molecule 0.787
Mmp12 matrix metallopeptidase 12 0.786
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.782
Tgfbr2 transforming growth factor, beta receptor II 0.735
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.727
Junb jun B proto-oncogene 0.715
Itgam integrin, alpha M 0.703
Fgfr2 fibroblast growth factor receptor 2 0.700
Pth parathyroid hormone 0.689
Otx1 orthodenticle homeobox 1 0.685
Prrx1 paired related homeobox 1 0.682
Ccl2 chemokine (C-C motif) ligand 2 0.682
Dlgap2 discs, large (Drosophila) homolog-associated protein 2 0.673
Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor 0.667
Ucn urocortin 0.659
Met met proto-oncogene 0.641
Cxcl10 chemokine (C-X-C motif) ligand 10 0.640
Cd4 Cd4 molecule 0.639
Pecam1 platelet/endothelial cell adhesion molecule 1 0.638
Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 0.630
Neurog3 neurogenin 3 0.622
Ccr2 chemokine (C-C motif) receptor 2 0.621
Sstr1 somatostatin receptor 1 0.620
Tcf4 transcription factor 4 0.615
Adora2a adenosine A2a receptor 0.610
Agtr1a angiotensin II receptor, type 1a 0.604
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.603
Gja1 gap junction protein, alpha 1 0.601
Bmp6 bone morphogenetic protein 6 0.596
Hoxa2 homeo box A2 0.595
Hspb1 heat shock protein 1 0.592
Ccl3 chemokine (C-C motif) ligand 3 0.590
Scn9a sodium channel, voltage-gated, type IX, alpha 0.589
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.589
Trhr2 thyrotropin releasing hormone receptor 2 0.589
Ptafr platelet-activating factor receptor 0.584
Zfp36 zinc finger protein 36 0.578
RGD1564664 similar to LOC387763 protein 0.578
Atf3 activating transcription factor 3 0.577
Syt4 synaptotagmin IV 0.562
Syt10 synaptotagmin X 0.559
Nrxn1 neurexin 1 0.558
Phkg1 phosphorylase kinase, gamma 1 0.556
Oprd1 opioid receptor, delta 1 0.554
Plau plasminogen activator, urokinase 0.552
Chrnb3 cholinergic receptor, nicotinic, beta 3 0.548
Sox17 SRY (sex determining region Y)-box 17 0.545
Nos2 nitric oxide synthase 2, inducible 0.543
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.542
Mc5r melanocortin 5 receptor 0.541
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.539
Sirpa signal-regulatory protein alpha 0.528
Sstr5 somatostatin receptor 5 0.528
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.525
Ahsg alpha-2-HS-glycoprotein 0.525
Nefh neurofilament, heavy polypeptide 0.524
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.520
Ifitm3 interferon induced transmembrane protein 3 0.519
Prap1 proline-rich acidic protein 1 0.518
Cckar cholecystokinin A receptor 0.517
Foxd1 forkhead box D1 0.516
Notch2 Notch homolog 2 (Drosophila) 0.515
Dbh dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.515
LOC60591 calcium-activated potassium channel beta subunit 0.514
Adam17 ADAM metallopeptidase domain 17 0.514
Stat3 signal transducer and activator of transcription 3 0.511
Fgf18 fibroblast growth factor 18 0.510
Gja5 gap junction protein, alpha 5 0.507
Oxtr oxytocin receptor 0.503
Fgf10 fibroblast growth factor 10 0.501
Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 0.500
Calcrl calcitonin receptor-like 0.499
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.498
Errfi1 ERBB receptor feedback inhibitor 1 0.497
Dmd dystrophin 0.494
Pgc progastricsin (pepsinogen C) 0.487
Nrcam neuronal cell adhesion molecule 0.485
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.484
Eef2 eukaryotic translation elongation factor 2 0.483
Ier3 immediate early response 3 0.482
Il1rl1 interleukin 1 receptor-like 1 0.476
Anxa1 annexin A1 0.474
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.473
Cntn2 contactin 2 (axonal) 0.471
Uncx UNC homeobox 0.468
Itgb7 integrin, beta 7 0.466
Mif macrophage migration inhibitory factor 0.466
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.465
Reg3g regenerating islet-derived 3 gamma 0.464
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.464
Egr2 early growth response 2 0.463
Spt1 salivary protein 1 0.462
Zp1 zona pellucida glycoprotein 1 (sperm receptor) 0.461
Shc2 SHC (Src homology 2 domain containing) transforming protein 2 0.460
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
hlh-2 Protein HLH-2 0.849
egl-18 Protein EGL-18 0.816
dim-1 Protein DIM-1 0.763
elt-6 Protein ELT-6 0.753
unc-73 Protein UNC-73 0.727
sem-5 Protein SEM-5 0.722
unc-62 Protein UNC-62 0.707
egl-13 Protein EGL-13 0.679
inx-12 Protein INX-12 0.664
hlh-1 Protein HLH-1 0.638
bar-1 Protein BAR-1 0.582
unc-52 Protein UNC-52 0.557
egl-46 Protein EGL-46 0.548
vab-3 Protein VAB-3 0.503
daf-4 Protein DAF-4 0.499
nhr-2 Protein NHR-2 0.498
egl-8 Protein EGL-8 0.496
col-17 Protein COL-17 0.476
cye-1 Protein CYE-1 0.467
smp-1 Protein SMP-1 0.456
plc-1 Protein PLC-1 0.451
eor-2 Protein EOR-2 0.447
mab-5 Protein MAB-5 0.446
lin-36 Protein LIN-36 0.443
col-154 Protein COL-154 0.440
prp-8 Protein PRP-8 0.435
col-157 Protein COL-157 0.431
glp-1 Protein GLP-1 0.427
anc-1 Protein ANC-1 0.424
ajm-1 Protein AJM-1 0.423
fln-2 Protein FLN-2 0.422
sma-6 Protein SMA-6 0.422
mes-3 Protein MES-3 0.403
inx-3 Protein INX-3 0.399
sdz-28 Protein SDZ-28 0.395
lrp-1 Protein LRP-1 0.395
ten-1 Protein TEN-1 0.392
mep-1 Protein MEP-1 0.383
dre-1 Protein DRE-1 0.382
syg-1 Protein SYG-1 0.382
nola-3 Protein NOLA-3 0.379
nhr-25 Protein NHR-25 0.375
ndk-1 Protein NDK-1 0.373
fkh-2 Protein FKH-2 0.372
nhr-67 Protein NHR-67 0.361
sur-2 Protein SUR-2 0.341
pha-4 Protein PHA-4 0.341
C14C10.5 Protein C14C10.5 0.340
zyg-8 Protein ZYG-8 0.338
sli-1 Protein SLI-1 0.337
abl-1 Protein ABL-1 0.337
hcp-3 Protein HCP-3 0.335
madf-5 Protein MADF-5 0.334
inx-5 Protein INX-5 0.332
C54E4.2 Protein C54E4.2 0.328
adt-2 Protein ADT-2 0.326
ZK84.1 Protein ZK84.1 0.324
T28F4.1 Protein T28F4.1 0.323
lag-1 Protein LAG-1 0.321
daf-12 Protein DAF-12 0.321
col-92 Protein COL-92 0.319
unc-83 Protein UNC-83 0.318
lir-1 Protein LIR-1 0.317
efn-2 Protein EFN-2 0.316
dpl-1 Protein DPL-1 0.313
ZK484.1 Protein ZK484.1 0.311
inx-8 Protein INX-8 0.311
tag-260 Protein TAG-260 0.309
vav-1 Protein VAV-1 0.307
unc-86 Protein UNC-86 0.304
rol-8 Protein ROL-8 0.303
skp-1 Protein SKP-1 0.302
peb-1 Protein PEB-1 0.302
pal-1 Protein PAL-1 0.301
col-34 Protein COL-34 0.301
sec-10 Protein SEC-10 0.294
rars-1 Protein RARS-1 0.294
unc-16 Protein UNC-16 0.293
pry-1 Protein PRY-1 0.291
dig-1 Protein DIG-1 0.291
W05F2.3 Protein W05F2.3 0.291
F31F7.1 Protein F31F7.1 0.289
pmk-1 Protein PMK-1 0.289
msp-55 Protein MSP-55 0.289
T08A11.2 Protein T08A11.2 0.288
unc-104 Protein UNC-104 0.288
daf-5 Protein DAF-5 0.288
inx-13 Protein INX-13 0.287
tba-1 Protein TBA-1 0.286
unc-32 Protein UNC-32 0.285
sma-1 Protein SMA-1 0.283
hpo-32 Protein HPO-32 0.279
T28D9.4 Protein T28D9.4 0.279
hcp-6 Protein HCP-6 0.277
eps-8 Protein EPS-8 0.277
hmg-1.1 Protein HMG-1.1 0.275
plc-3 Protein PLC-3 0.273
pde-4 Protein PDE-4 0.272
deb-1 Protein DEB-1 0.271
mtm-3 Protein MTM-3 0.270
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Danio rerio
Name Description Probability Func Analog Organism
pax2a paired box gene 2a 0.977
cdh2 cadherin 2, neuronal 0.850
gli1 GLI-Kruppel family member 1 0.813
fgfr1a fibroblast growth factor receptor 1a 0.726
shha sonic hedgehog a 0.626
alcama activated leukocyte cell adhesion molecule a 0.589
tal1 T-cell acute lymphocytic leukemia 1 0.539
tbx1 T-box 1 0.467
nrg2a neuregulin 2a 0.454
jag2 jagged 2 0.443
bmp2b bone morphogenetic protein 2b 0.440
gata3 GATA-binding protein 3 0.405
myod1 myogenic differentiation 1 0.390
pax8 paired box gene 8 0.385
alcamb activated leukocyte cell adhesion molecule b 0.383
mapk1 mitogen-activated protein kinase 1 0.352
jag1b jagged 1b 0.325
hoxd4a homeo box D4a 0.320
fgf17 fibroblast growth factor 17 0.320
foxi1 forkhead box I1 0.301
gdf6a growth differentiation factor 6a 0.298
dcc deleted in colorectal carcinoma 0.293
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.263
tardbp TAR DNA binding protein 0.254
sema3ab semaphorin 3ab 0.250
plagl2 pleiomorphic adenoma gene-like 2 0.248
twist1a twist1a 0.246
foxa2 forkhead box A2 0.241
pea3 ETS-domain transcription factor pea3 0.228
wnt4a wingless-type MMTV integration site family, member 4a 0.226
efnb2a ephrin B2a 0.226
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.225
notch3 notch homolog 3 0.223
chd chordin 0.223
gata2a GATA-binding protein 2a 0.214
sox9b SRY-box containing gene 9b 0.212
jun jun proto-oncogene 0.211
lamb1a laminin, beta 1a 0.210
lmna lamin A 0.202
met met proto-oncogene (hepatocyte growth factor receptor) 0.199
dharma dharma 0.193
lama4 laminin, alpha 4 0.192
klf4a Kruppel-like transcription factor 4a 0.189
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.188
wnt10a wingless-type MMTV integration site family, member 10a 0.188
ptch2 patched 2 0.184
zbtb4 zinc finger and BTB domain containing 4 0.183
sulf1 sulfatase 1 0.181
wnt11r wingless-type MMTV integration site family, member 11, related 0.181
ndr2 nodal-related 2 0.180
hoxa13b homeo box A13b 0.165
plcg1 phospholipase C, gamma 1 0.158
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.154
tbx20 T-box 20 0.148
rag1 recombination activating gene 1 0.147
dag1 dystroglycan 1 0.147
aurkb aurora kinase B 0.146
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.145
bmp2a bone morphogenetic protein 2a 0.140
otx1b orthodenticle homolog 1b 0.138
lypd6 LY6/PLAUR domain containing 6 0.136
amotl2a angiomotin like 2a 0.136
adra2b adrenergic, alpha-2B-, receptor 0.136
isl1 islet1 0.132
nrp1a neuropilin 1a 0.131
dnmt4 DNA (cytosine-5-)-methyltransferase 4 0.130
igf1rb insulin-like growth factor 1b receptor 0.130
nppa natriuretic peptide precursor A 0.126
ascl1a achaete-scute complex-like 1a (Drosophila) 0.125
spns2 spinster homolog 2 (Drosophila) 0.125
pycard PYD and CARD domain containing 0.120
otx5 orthodenticle homolog 5 0.120
fabp7a fatty acid binding protein 7, brain, a 0.119
mstnb myostatin b 0.118
tbx18 T-box 18 0.117
hoxc6b homeo box C6b 0.117
tll1 tolloid-like 1 0.116
traf4a tnf receptor-associated factor 4a 0.116
thrb thyroid hormone receptor beta 0.115
m17 IL-6 subfamily cytokine M17 0.114
evx1 even-skipped homeobox 1 0.114
runx1 runt-related transcription factor 1 0.114
acvr2b activin receptor IIb 0.113
fgf19 fibroblast growth factor 19 0.113
nkx2.2a NK2 transcription factor related 2a 0.112
pdlim4 PDZ and LIM domain 4 0.112
ntn1b netrin 1b 0.112
wt1a wilms tumor 1a 0.110
fras1 Fraser syndrome 1 0.110
hoxd13a homeo box D13a 0.109
bms1l BMS1-like, ribosome assembly protein (yeast) 0.108
sox9a SRY-box containing gene 9a 0.107
slit3 slit (Drosophila) homolog 3 0.106
bmp4 bone morphogenetic protein 4 0.106
hsp90a.2 heat shock protein 90-alpha 2 0.106
dlb deltaB 0.102
sall1a sal-like 1a (Drosophila) 0.101
fezf2 FEZ family zinc finger 2 0.100
twist3 twist3 0.099
col15a1b collagen, type XV, alpha 1b 0.099
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.988
EcR Ecdysone receptor 0.971
Egfr Epidermal growth factor receptor 0.967
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.957
tsr twinstar 0.953
wg wingless 0.930
phl pole hole 0.922
Fmr1 CG6203 gene product from transcript CG6203-RC 0.909
HLHm7 E(spl) region transcript m7 0.905
Tak1 TGF-beta activated kinase 1 0.896
TBPH CG10327 gene product from transcript CG10327-RC 0.870
bsk basket 0.869
dsh dishevelled 0.845
ecd ecdysoneless 0.838
sgg shaggy 0.836
babo baboon 0.822
abd-A abdominal A 0.802
slmb supernumerary limbs 0.755
eIF-4E Eukaryotic initiation factor 4E 0.745
shn schnurri 0.741
rut rutabaga 0.740
unc-13 CG2999 gene product from transcript CG2999-RA 0.738
Mad Mothers against dpp 0.722
lola longitudinals lacking 0.697
G-oalpha47A G protein oalpha 47A 0.695
Nrg Neuroglian 0.685
cpa capping protein alpha 0.680
CG11347 CG11347 gene product from transcript CG11347-RE 0.678
ap apterous 0.658
Smox Smad on X 0.657
Stat92E Signal-transducer and activator of transcription protein at 92E 0.635
Fas2 Fasciclin 2 0.632
Pk61C Protein kinase 61C 0.632
Akt1 CG4006 gene product from transcript CG4006-RA 0.626
hth homothorax 0.613
rictor rapamycin-insensitive companion of Tor 0.610
hh hedgehog 0.599
klu klumpfuss 0.591
E(spl) Enhancer of split 0.590
dally division abnormally delayed 0.563
nej nejire 0.559
CaMKII Calcium/calmodulin-dependent protein kinase II 0.550
slp1 sloppy paired 1 0.545
Tl Toll 0.527
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.527
foxo forkhead box, sub-group O 0.520
drk downstream of receptor kinase 0.509
RYBP Ring and YY1 Binding Protein 0.497
HLHmbeta E(spl) region transcript mbeta 0.487
Antp Antennapedia 0.479
zfh1 Zn finger homeodomain 1 0.476
eya eyes absent 0.468
CycD Cyclin D 0.464
mbc myoblast city 0.460
InR Insulin-like receptor 0.459
SoxN SoxNeuro 0.456
CrebB-17A Cyclic-AMP response element binding protein B at 17A 0.453
msps mini spindles 0.451
hep hemipterous 0.445
nwk nervous wreck 0.442
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.437
Cat Catalase 0.433
emc extra macrochaetae 0.428
Wnt4 Wnt oncogene analog 4 0.428
stg string 0.425
Dap160 Dynamin associated protein 160 0.420
ovo CG6824 gene product from transcript CG6824-RE 0.419
CG12424 CG12424 gene product from transcript CG12424-RC 0.412
Dab Disabled 0.404
Pak PAK-kinase 0.401
robo3 CG5423 gene product from transcript CG5423-RA 0.400
kn knot 0.399
wit wishful thinking 0.391
Su(H) Suppressor of Hairless 0.385
lea leak 0.385
gt giant 0.378
gro groucho 0.375
ato atonal 0.374
rl rolled 0.372
Ilp2 Insulin-like peptide 2 0.371
wts warts 0.367
S6k RPS6-p70-protein kinase 0.367
bowl brother of odd with entrails limited 0.366
oc ocelliless 0.364
tutl turtle 0.361
CkIIalpha Casein kinase II alpha subunit 0.360
shot short stop 0.359
Ilp5 Insulin-like peptide 5 0.357
NetB Netrin-B 0.357
dpp decapentaplegic 0.348
LIMK1 LIM-kinase1 0.348
pb proboscipedia 0.344
fz2 frizzled 2 0.343
CycB Cyclin B 0.341
Rheb CG1081 gene product from transcript CG1081-RA 0.338
chico CG5686 gene product from transcript CG5686-RB 0.337
ftz-f1 ftz transcription factor 1 0.335
mid midline 0.335
polo CG12306 gene product from transcript CG12306-RA 0.327
crol crooked legs 0.325
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism