The network for 'intrahepatic bile duct development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

intrahepatic bile duct development

The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).

Name Description Probability Func Analog Organism
rarab retinoic acid receptor, alpha b 0.422
hnf1ba HNF1 homeobox Ba 0.360
raraa retinoic acid receptor, alpha a 0.355
sox9b SRY-box containing gene 9b 0.287
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.244
mxi1 max interacting protein 0.239
cry3 cryptochrome 3 0.220
nr1d2b nuclear receptor subfamily 1, group D, member 2b 0.191
rxrga retinoid x receptor, gamma a 0.148
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.122
osr2 odd-skipped related 2 (Drosophila) 0.114
rbm19 RNA binding motif protein 19 0.110
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.110
egr1 early growth response 1 0.108
cldn15lb claudin 15-like b 0.093
nr1d2a nuclear receptor subfamily 1, group D, member 2a 0.093
cdx4 caudal type homeo box transcription factor 4 0.070
c11orf2 c11orf2 homolog (H. sapiens) 0.065
her7 hairy and enhancer of split related-7 0.062
rxraa retinoid X receptor, alpha a 0.061
hdac4 histone deacetylase 4 0.060
dnmt8 DNA (cytosine-5-)-methyltransferase 8 0.058
kctd15a potassium channel tetramerisation domain containing 15a 0.055
sox17 SRY-box containing gene 17 0.053
met met proto-oncogene (hepatocyte growth factor receptor) 0.046
rxrbb retinoid x receptor, beta b 0.041
efnb2a ephrin B2a 0.040
dusp2 dual specificity phosphatase 2 0.040
hsf2 heat shock factor 2 0.039
atp6v1h ATPase, H+ transporting, lysosomal, V1 subunit H 0.038
wt1b wilms tumor 1b 0.037
pdzk1 PDZ domain containing 1 0.037
atp6v1f ATPase, H+ transporting, V1 subunit F 0.036
foxa3 forkhead box A3 0.036
atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 0.035
tbx20 T-box 20 0.035
tbx2b T-box 2b 0.035
rab11bb RAB11B, member RAS oncogene family, b 0.034
mnx1 motor neuron and pancreas homeobox 1 0.034
gle1 GLE1 RNA export mediator homolog (yeast) 0.029
egr2b early growth response 2b 0.028
fgf20b fibroblast growth factor 20b 0.028
nrp2b neuropilin 2b 0.028
atp6v1e1b ATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b 0.028
her1 hairy-related 1 0.027
atp6v0d1 ATPase, H+ transporting, V0 subunit D isoform 1 0.027
esrrga estrogen-related receptor gamma a 0.026
atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 0.025
slc4a4a solute carrier family 4, member 4a 0.023
prox2 prospero homeobox 2 0.023
irx3b iroquois homeobox protein 3b 0.023
ahctf1 AT hook containing transcription factor 1 0.022
gas6 growth arrest-specific 6 0.022
gabarapa GABA(A) receptor-associated protein a 0.022
prdm5 PR domain containing 5 0.022
hoxb1a homeo box B1a 0.021
gria3b glutamate receptor, ionotrophic, AMPA 3b 0.021
kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 0.021
nr1d1 nuclear receptor subfamily 1, group d, member 1 0.021
rfx2 regulatory factor X, 2 (influences HLA class II expression) 0.020
fam20b family with sequence similarity 20, member B (H. sapiens) 0.020
sp5l Sp5 transcription factor-like 0.020
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.020
gpr22 G protein-coupled receptor 22 0.019
atp6v1d ATPase, H+ transporting, V1 subunit D and ATPase, H+ transporting, V1 subunit D 0.019
jhdm1da jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae) 0.019
spata2 spermatogenesis associated 2 0.019
fgf8a fibroblast growth factor 8 a 0.018
efna3b ephrin A3b 0.018
pax6b paired box gene 6b 0.018
dctn1a dynactin 1a 0.018
homez homeodomain leucine zipper gene 0.018
thrab thyroid hormone receptor alpha b 0.018
selp selectin P 0.018
hoxb1b homeo box B1b 0.018
smyd3 SET and MYND domain containing 3 0.017
nkx2.5 NK2 transcription factor related 5 0.017
gbx1 gastrulation brain homeobox 1 0.017
osr1 odd-skipped related 1 (Drosophila) 0.017
atp6v1g1 ATPase, H+ transporting, V1 subunit G isoform 1 0.016
lass2 LAG1 homolog, ceramide synthase 2 (S. cerevisiae) 0.016
nkx6.2 NK6 transcription factor related, locus 2 0.016
cacnb3a calcium channel, voltage-dependent, beta 3a 0.015
ccdc85al coiled-coil domain containing 85A, like 0.015
csnk1db casein kinase 1, delta b 0.015
rxrba retinoid x receptor, beta a 0.015
rnpc3 RNA-binding region (RNP1, RRM) containing 3 0.015
sb:cb648 sb:cb648 0.015
gdf6a growth differentiation factor 6a 0.014
pes pescadillo 0.014
jag2 jagged 2 0.014
spry2 sprouty homolog 2 0.014
zgc:112421 zgc:112421 0.014
crx cone-rod homeobox 0.014
dlg1 discs, large (Drosophila) homolog 1 0.014
ifng1-1 interferon, gamma 1-1 0.013
rgs8 regulator of G-protein signaling 8 0.013
slc6a8 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 0.013
adora2aa adenosine A2a receptor a 0.013
sv2b synaptic vesicle glycoprotein 2 b 0.013
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Pax2 paired box gene 2 0.984
Gli3 GLI-Kruppel family member GLI3 0.946
Isl1 ISL1 transcription factor, LIM/homeodomain 0.923
Fgfr2 fibroblast growth factor receptor 2 0.908
Bmp4 bone morphogenetic protein 4 0.906
Shh sonic hedgehog 0.885
Pax3 paired box gene 3 0.831
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.784
Rara retinoic acid receptor, alpha 0.779
Hes1 hairy and enhancer of split 1 (Drosophila) 0.757
Meox2 mesenchyme homeobox 2 0.731
Fgf10 fibroblast growth factor 10 0.699
Fgf8 fibroblast growth factor 8 0.693
Rarb retinoic acid receptor, beta 0.648
Eya1 eyes absent 1 homolog (Drosophila) 0.606
Emx2 empty spiracles homolog 2 (Drosophila) 0.560
Sox4 SRY-box containing gene 4 0.501
Pitx2 paired-like homeodomain transcription factor 2 0.429
Foxg1 forkhead box G1 0.411
Rxra retinoid X receptor alpha 0.373
Otx2 orthodenticle homolog 2 (Drosophila) 0.360
Rb1 retinoblastoma 1 0.349
Chd7 chromodomain helicase DNA binding protein 7 0.323
Jag1 jagged 1 0.320
Tcfap2a transcription factor AP-2, alpha 0.289
Onecut2 one cut domain, family member 2 0.255
Otx1 orthodenticle homolog 1 (Drosophila) 0.215
Pax6 paired box gene 6 0.213
She src homology 2 domain-containing transforming protein E 0.194
Cldn5 claudin 5 0.186
Sox2 SRY-box containing gene 2 0.184
Gata3 GATA binding protein 3 0.182
Efnb2 ephrin B2 0.176
Gli2 GLI-Kruppel family member GLI2 0.173
Hhex hematopoietically expressed homeobox 0.170
Smo smoothened homolog (Drosophila) 0.156
Zeb1 zinc finger E-box binding homeobox 1 0.155
Ptprb protein tyrosine phosphatase, receptor type, B 0.151
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.150
Pou3f3 POU domain, class 3, transcription factor 3 0.150
Tbx2 T-box 2 0.148
Pkd1 polycystic kidney disease 1 homolog 0.144
Hoxa5 homeobox A5 0.142
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.140
Ednra endothelin receptor type A 0.137
Nf1 neurofibromatosis 1 0.124
Fgfr1 fibroblast growth factor receptor 1 0.113
Nkx6-1 NK6 homeobox 1 0.111
Fgfr3 fibroblast growth factor receptor 3 0.110
Fgf3 fibroblast growth factor 3 0.107
Cys1 cystin 1 0.103
Esam endothelial cell-specific adhesion molecule 0.101
Gata4 GATA binding protein 4 0.100
Hoxa3 homeobox A3 0.098
Atp6v1c1 ATPase, H+ transporting, lysosomal V1 subunit C1 0.098
Ikbkap inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein 0.095
Sox9 SRY-box containing gene 9 0.094
Sox11 SRY-box containing gene 11 0.093
Vangl2 vang-like 2 (van gogh, Drosophila) 0.092
Foxc2 forkhead box C2 0.091
Lef1 lymphoid enhancer binding factor 1 0.087
Tgfb2 transforming growth factor, beta 2 0.086
Rasip1 Ras interacting protein 1 0.085
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.085
Sox18 SRY-box containing gene 18 0.084
Lhx1 LIM homeobox protein 1 0.084
Insm1 insulinoma-associated 1 0.084
Sall3 sal-like 3 (Drosophila) 0.082
Bmper BMP-binding endothelial regulator 0.077
Eng endoglin 0.077
Hdac1 histone deacetylase 1 0.073
Hesx1 homeobox gene expressed in ES cells 0.072
Alx4 aristaless-like homeobox 4 0.068
Emcn endomucin 0.068
Nog noggin 0.066
Trp53 transformation related protein 53 0.066
Foxc1 forkhead box C1 0.063
Tbx1 T-box 1 0.061
Cdh5 cadherin 5 0.061
Hes5 hairy and enhancer of split 5 (Drosophila) 0.058
Aplnr apelin receptor 0.056
Fgf4 fibroblast growth factor 4 0.056
Hand1 heart and neural crest derivatives expressed transcript 1 0.055
Bmp7 bone morphogenetic protein 7 0.053
Onecut1 one cut domain, family member 1 0.052
Kdr kinase insert domain protein receptor 0.051
Hey1 hairy/enhancer-of-split related with YRPW motif 1 0.051
Gbx2 gastrulation brain homeobox 2 0.049
Pou3f1 POU domain, class 3, transcription factor 1 0.048
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.048
Nanog Nanog homeobox 0.046
Pofut1 protein O-fucosyltransferase 1 0.045
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.045
Tek endothelial-specific receptor tyrosine kinase 0.044
Kit kit oncogene 0.044
Rarg retinoic acid receptor, gamma 0.043
Tbx10 T-box 10 0.042
Tbx3 T-box 3 0.042
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D 0.042
Trp63 transformation related protein 63 0.042
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism