Process View
The network for 'intrahepatic bile duct development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| rarab | retinoic acid receptor, alpha b | 0.422 | |
| hnf1ba | HNF1 homeobox Ba | 0.360 | |
| raraa | retinoic acid receptor, alpha a | 0.355 | |
| sox9b | SRY-box containing gene 9b | 0.287 | |
| pwp2h | PWP2 periodic tryptophan protein homolog (yeast) | 0.244 | |
| mxi1 | max interacting protein | 0.239 | |
| cry3 | cryptochrome 3 | 0.220 | |
| nr1d2b | nuclear receptor subfamily 1, group D, member 2b | 0.191 | |
| rxrga | retinoid x receptor, gamma a | 0.148 | |
| cdipt | CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) | 0.122 | |
| osr2 | odd-skipped related 2 (Drosophila) | 0.114 | |
| rbm19 | RNA binding motif protein 19 | 0.110 | |
| cyp26a1 | cytochrome P450, subfamily XXVIA, polypeptide 1 | 0.110 | |
| egr1 | early growth response 1 | 0.108 | |
| cldn15lb | claudin 15-like b | 0.093 | |
| nr1d2a | nuclear receptor subfamily 1, group D, member 2a | 0.093 | |
| cdx4 | caudal type homeo box transcription factor 4 | 0.070 | |
| c11orf2 | c11orf2 homolog (H. sapiens) | 0.065 | |
| her7 | hairy and enhancer of split related-7 | 0.062 | |
| rxraa | retinoid X receptor, alpha a | 0.061 | |
| hdac4 | histone deacetylase 4 | 0.060 | |
| dnmt8 | DNA (cytosine-5-)-methyltransferase 8 | 0.058 | |
| kctd15a | potassium channel tetramerisation domain containing 15a | 0.055 | |
| sox17 | SRY-box containing gene 17 | 0.053 | |
| met | met proto-oncogene (hepatocyte growth factor receptor) | 0.046 | |
| rxrbb | retinoid x receptor, beta b | 0.041 | |
| efnb2a | ephrin B2a | 0.040 | |
| dusp2 | dual specificity phosphatase 2 | 0.040 | |
| hsf2 | heat shock factor 2 | 0.039 | |
| atp6v1h | ATPase, H+ transporting, lysosomal, V1 subunit H | 0.038 | |
| wt1b | wilms tumor 1b | 0.037 | |
| pdzk1 | PDZ domain containing 1 | 0.037 | |
| atp6v1f | ATPase, H+ transporting, V1 subunit F | 0.036 | |
| foxa3 | forkhead box A3 | 0.036 | |
| atp6ap2 | ATPase, H+ transporting, lysosomal accessory protein 2 | 0.035 | |
| tbx20 | T-box 20 | 0.035 | |
| tbx2b | T-box 2b | 0.035 | |
| rab11bb | RAB11B, member RAS oncogene family, b | 0.034 | |
| mnx1 | motor neuron and pancreas homeobox 1 | 0.034 | |
| gle1 | GLE1 RNA export mediator homolog (yeast) | 0.029 | |
| egr2b | early growth response 2b | 0.028 | |
| fgf20b | fibroblast growth factor 20b | 0.028 | |
| nrp2b | neuropilin 2b | 0.028 | |
| atp6v1e1b | ATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b | 0.028 | |
| her1 | hairy-related 1 | 0.027 | |
| atp6v0d1 | ATPase, H+ transporting, V0 subunit D isoform 1 | 0.027 | |
| esrrga | estrogen-related receptor gamma a | 0.026 | |
| atp6ap1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.025 | |
| slc4a4a | solute carrier family 4, member 4a | 0.023 | |
| prox2 | prospero homeobox 2 | 0.023 | |
| irx3b | iroquois homeobox protein 3b | 0.023 | |
| ahctf1 | AT hook containing transcription factor 1 | 0.022 | |
| gas6 | growth arrest-specific 6 | 0.022 | |
| gabarapa | GABA(A) receptor-associated protein a | 0.022 | |
| prdm5 | PR domain containing 5 | 0.022 | |
| hoxb1a | homeo box B1a | 0.021 | |
| gria3b | glutamate receptor, ionotrophic, AMPA 3b | 0.021 | |
| kcnj1 | potassium inwardly-rectifying channel, subfamily J, member 1 | 0.021 | |
| nr1d1 | nuclear receptor subfamily 1, group d, member 1 | 0.021 | |
| rfx2 | regulatory factor X, 2 (influences HLA class II expression) | 0.020 | |
| fam20b | family with sequence similarity 20, member B (H. sapiens) | 0.020 | |
| sp5l | Sp5 transcription factor-like | 0.020 | |
| nr3c1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.020 | |
| gpr22 | G protein-coupled receptor 22 | 0.019 | |
| atp6v1d | ATPase, H+ transporting, V1 subunit D and ATPase, H+ transporting, V1 subunit D | 0.019 | |
| jhdm1da | jumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae) | 0.019 | |
| spata2 | spermatogenesis associated 2 | 0.019 | |
| fgf8a | fibroblast growth factor 8 a | 0.018 | |
| efna3b | ephrin A3b | 0.018 | |
| pax6b | paired box gene 6b | 0.018 | |
| dctn1a | dynactin 1a | 0.018 | |
| homez | homeodomain leucine zipper gene | 0.018 | |
| thrab | thyroid hormone receptor alpha b | 0.018 | |
| selp | selectin P | 0.018 | |
| hoxb1b | homeo box B1b | 0.018 | |
| smyd3 | SET and MYND domain containing 3 | 0.017 | |
| nkx2.5 | NK2 transcription factor related 5 | 0.017 | |
| gbx1 | gastrulation brain homeobox 1 | 0.017 | |
| osr1 | odd-skipped related 1 (Drosophila) | 0.017 | |
| atp6v1g1 | ATPase, H+ transporting, V1 subunit G isoform 1 | 0.016 | |
| lass2 | LAG1 homolog, ceramide synthase 2 (S. cerevisiae) | 0.016 | |
| nkx6.2 | NK6 transcription factor related, locus 2 | 0.016 | |
| cacnb3a | calcium channel, voltage-dependent, beta 3a | 0.015 | |
| ccdc85al | coiled-coil domain containing 85A, like | 0.015 | |
| csnk1db | casein kinase 1, delta b | 0.015 | |
| rxrba | retinoid x receptor, beta a | 0.015 | |
| rnpc3 | RNA-binding region (RNP1, RRM) containing 3 | 0.015 | |
| sb:cb648 | sb:cb648 | 0.015 | |
| gdf6a | growth differentiation factor 6a | 0.014 | |
| pes | pescadillo | 0.014 | |
| jag2 | jagged 2 | 0.014 | |
| spry2 | sprouty homolog 2 | 0.014 | |
| zgc:112421 | zgc:112421 | 0.014 | |
| crx | cone-rod homeobox | 0.014 | |
| dlg1 | discs, large (Drosophila) homolog 1 | 0.014 | |
| ifng1-1 | interferon, gamma 1-1 | 0.013 | |
| rgs8 | regulator of G-protein signaling 8 | 0.013 | |
| slc6a8 | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 0.013 | |
| adora2aa | adenosine A2a receptor a | 0.013 | |
| sv2b | synaptic vesicle glycoprotein 2 b | 0.013 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pax2 | paired box gene 2 | 0.984 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.946 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.923 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.908 | |
| Bmp4 | bone morphogenetic protein 4 | 0.906 | |
| Shh | sonic hedgehog | 0.885 | |
| Pax3 | paired box gene 3 | 0.831 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.784 | |
| Rara | retinoic acid receptor, alpha | 0.779 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.757 | |
| Meox2 | mesenchyme homeobox 2 | 0.731 | |
| Fgf10 | fibroblast growth factor 10 | 0.699 | |
| Fgf8 | fibroblast growth factor 8 | 0.693 | |
| Rarb | retinoic acid receptor, beta | 0.648 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.606 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.560 | |
| Sox4 | SRY-box containing gene 4 | 0.501 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.429 | |
| Foxg1 | forkhead box G1 | 0.411 | |
| Rxra | retinoid X receptor alpha | 0.373 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.360 | |
| Rb1 | retinoblastoma 1 | 0.349 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.323 | |
| Jag1 | jagged 1 | 0.320 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.289 | |
| Onecut2 | one cut domain, family member 2 | 0.255 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.215 | |
| Pax6 | paired box gene 6 | 0.213 | |
| She | src homology 2 domain-containing transforming protein E | 0.194 | |
| Cldn5 | claudin 5 | 0.186 | |
| Sox2 | SRY-box containing gene 2 | 0.184 | |
| Gata3 | GATA binding protein 3 | 0.182 | |
| Efnb2 | ephrin B2 | 0.176 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.173 | |
| Hhex | hematopoietically expressed homeobox | 0.170 | |
| Smo | smoothened homolog (Drosophila) | 0.156 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.155 | |
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.151 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.150 | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.150 | |
| Tbx2 | T-box 2 | 0.148 | |
| Pkd1 | polycystic kidney disease 1 homolog | 0.144 | |
| Hoxa5 | homeobox A5 | 0.142 | |
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.140 | |
| Ednra | endothelin receptor type A | 0.137 | |
| Nf1 | neurofibromatosis 1 | 0.124 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.113 | |
| Nkx6-1 | NK6 homeobox 1 | 0.111 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.110 | |
| Fgf3 | fibroblast growth factor 3 | 0.107 | |
| Cys1 | cystin 1 | 0.103 | |
| Esam | endothelial cell-specific adhesion molecule | 0.101 | |
| Gata4 | GATA binding protein 4 | 0.100 | |
| Hoxa3 | homeobox A3 | 0.098 | |
| Atp6v1c1 | ATPase, H+ transporting, lysosomal V1 subunit C1 | 0.098 | |
| Ikbkap | inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein | 0.095 | |
| Sox9 | SRY-box containing gene 9 | 0.094 | |
| Sox11 | SRY-box containing gene 11 | 0.093 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.092 | |
| Foxc2 | forkhead box C2 | 0.091 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.087 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.086 | |
| Rasip1 | Ras interacting protein 1 | 0.085 | |
| Ezh2 | enhancer of zeste homolog 2 (Drosophila) | 0.085 | |
| Sox18 | SRY-box containing gene 18 | 0.084 | |
| Lhx1 | LIM homeobox protein 1 | 0.084 | |
| Insm1 | insulinoma-associated 1 | 0.084 | |
| Sall3 | sal-like 3 (Drosophila) | 0.082 | |
| Bmper | BMP-binding endothelial regulator | 0.077 | |
| Eng | endoglin | 0.077 | |
| Hdac1 | histone deacetylase 1 | 0.073 | |
| Hesx1 | homeobox gene expressed in ES cells | 0.072 | |
| Alx4 | aristaless-like homeobox 4 | 0.068 | |
| Emcn | endomucin | 0.068 | |
| Nog | noggin | 0.066 | |
| Trp53 | transformation related protein 53 | 0.066 | |
| Foxc1 | forkhead box C1 | 0.063 | |
| Tbx1 | T-box 1 | 0.061 | |
| Cdh5 | cadherin 5 | 0.061 | |
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.058 | |
| Aplnr | apelin receptor | 0.056 | |
| Fgf4 | fibroblast growth factor 4 | 0.056 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.055 | |
| Bmp7 | bone morphogenetic protein 7 | 0.053 | |
| Onecut1 | one cut domain, family member 1 | 0.052 | |
| Kdr | kinase insert domain protein receptor | 0.051 | |
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.051 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.049 | |
| Pou3f1 | POU domain, class 3, transcription factor 1 | 0.048 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.048 | |
| Nanog | Nanog homeobox | 0.046 | |
| Pofut1 | protein O-fucosyltransferase 1 | 0.045 | |
| Atp6v1a | ATPase, H+ transporting, lysosomal V1 subunit A | 0.045 | |
| Tek | endothelial-specific receptor tyrosine kinase | 0.044 | |
| Kit | kit oncogene | 0.044 | |
| Rarg | retinoic acid receptor, gamma | 0.043 | |
| Tbx10 | T-box 10 | 0.042 | |
| Tbx3 | T-box 3 | 0.042 | |
| Atp6v1d | ATPase, H+ transporting, lysosomal V1 subunit D | 0.042 | |
| Trp63 | transformation related protein 63 | 0.042 |