The network for 'response to food' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to food

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.

Danio rerio
Name Description Probability Func Analog Organism
prl prolactin 0.962
drd2a dopamine receptor D2a 0.882
drd2b dopamine receptor D2b 0.878
drd2l dopamine receptor D2 like 0.736
nlgn1 neuroligin 1 0.731
pcp4a Purkinje cell protein 4a 0.669
sst1.1 somatostatin 1, tandem duplicate 1 0.552
avpl arginine vasopressin-like 0.545
slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.437
pomca proopiomelanocortin a 0.408
cga glycoprotein hormones, alpha polypeptide 0.385
neurog3 neurogenin 3 0.370
otpa orthopedia homolog a 0.339
pou1f1 POU domain, class 1, transcription factor 1 0.325
ghrb growth hormone receptor b 0.309
gnrh2 gonadotropin-releasing hormone 2 0.302
tshb thyroid stimulating hormone, beta subunit 0.274
ghra growth hormone receptor a 0.257
fshb follicle stimulating hormone, beta polypeptide 0.209
si:dkey-228g21.4 si:dkey-228g21.4 0.174
mc4r melanocortin 4 receptor 0.173
drd3 dopamine receptor D3 0.173
crh corticotropin releasing hormone 0.172
cebpd CCAAT/enhancer binding protein (C/EBP), delta 0.160
LOC100006361 galanin-like 0.124
oprd1a opioid receptor, delta 1a 0.097
LOC100332193 growth hormone secretagogue receptor type 1-like 0.095
tac1 tachykinin 1 0.094
ros1 v-ros UR2 sarcoma virus oncogene homolog 1 (avian) 0.087
mao monoamine oxidase 0.086
oprk1 opioid receptor, kappa 1 0.083
LOC100001008 prepro-urotensin II-related peptide 0.082
gfra1b gdnf family receptor alpha 1b 0.082
nadl1.2 neural adhesion molecule L1.2 0.081
kiss2 kisspeptin 2 0.078
reln reelin 0.076
gja3 gap junction protein, alpha 3 0.076
exoc6 exocyst complex component 6 0.076
cnr1 cannabinoid receptor 1 0.075
ildr1b immunoglobulin-like domain containing receptor 1b 0.070
uts1 urotensin 1 0.069
rxfp1 relaxin/insulin-like family peptide receptor 1 0.068
per2 period homolog 2 (Drosophila) 0.066
junb jun B proto-oncogene 0.066
LOC567405 novel protein similar to vertebrate megakaryocyte-associated tyrosine kinase (MATK) 0.065
chat choline acetyltransferase 0.065
ar androgen receptor 0.064
gap43 growth associated protein 43 0.063
cnga5 cyclic nucleotide gated channel alpha 5 0.062
ddc dopa decarboxylase 0.062
lhb luteinizing hormone, beta polypeptide 0.061
sc:d0343 sc:d0343 0.061
slc17a6b solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b 0.061
igfbp1a insulin-like growth factor binding protein 1a 0.060
socs1 suppressor of cytokine signaling 1 0.060
si:ch211-233a1.8 si:ch211-233a1.8 0.060
stmn4 stathmin-like 4 0.059
drd1 dopamine receptor D1 0.057
roraa RAR-related orphan receptor A, paralog a 0.056
gli2b GLI-Kruppel family member GLI2b 0.054
xgb x globin 0.053
chrm2a cholinergic receptor, muscarinic 2a 0.053
dbh dopamine beta hydroxylase 0.052
nlgn3a neuroligin 3a 0.052
si:dkey-19f21.3 si:dkey-19f21.3 0.052
th2 tyrosine hydroxylase 2 0.049
oxtl oxytocin-like 0.046
adcyap1a adenylate cyclase activating polypeptide 1a 0.045
egr1 early growth response 1 0.045
cyp3c1 cytochrome P450, family 3, subfamily c, polypeptide 1 0.042
ntm neurotrimin 0.042
foxp2 forkhead box P2 0.042
pvrl1b poliovirus receptor-related 1b 0.041
vipr2 vasoactive intestinal peptide receptor 2 0.041
hgd homogentisate 1,2-dioxygenase 0.041
ntrk2b neurotrophic tyrosine kinase, receptor, type 2b 0.040
rrad Ras-related associated with diabetes 0.040
uts2a urotensin 2, alpha 0.038
cdkn1a cyclin-dependent kinase inhibitor 1A 0.038
scg3 secretogranin III 0.038
sp7 Sp7 transcription factor 0.038
mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.037
znf385b zinc finger protein 385B 0.036
wu:fj52c07 wu:fj52c07 0.036
spon1a spondin 1a 0.036
kiss1 KiSS-1 metastasis-suppressor 0.036
ntrk2a neurotrophic tyrosine kinase, receptor, type 2a 0.036
mapk8b mitogen-activated protein kinase 8b 0.035
zgc:77060 zgc:77060 0.035
zgc:172101 zgc:172101 0.035
adra2c adrenergic, alpha-2C-, receptor 0.035
dio2 deiodinase, iodothyronine, type II 0.034
bbs2 Bardet-Biedl syndrome 2 0.034
nlgn2a neuroligin 2a 0.034
ca2 carbonic anhydrase II 0.034
nlgn2b neuroligin 2b 0.034
crhbp corticotropin releasing hormone binding protein 0.034
fos v-fos FBJ murine osteosarcoma viral oncogene homolog 0.034
kiss1rb KISS1 receptor b 0.034
rln3a relaxin 3a 0.033
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
cat-1 Protein CAT-1 0.088
goa-1 Protein GOA-1 0.050
gpa-14 Protein GPA-14 0.029
tax-6 Protein TAX-6 0.019
egl-5 Protein EGL-5 0.019
CELE_Y51H4A.7 Protein Y51H4A.7 0.016
T23G4.3 Protein T23G4.3 0.016
pkg-1 Protein PKG-1 0.016
kcnl-2 Protein KCNL-2 0.015
bbs-8 Protein BBS-8 0.015
mxl-3 Protein MXL-3 0.014
unc-9 Protein UNC-9 0.014
gcy-34 Protein GCY-34 0.012
cmd-1 Protein CMD-1 0.012
kcc-2 Protein KCC-2 0.012
twk-30 Protein TWK-30 0.012
eat-2 Protein EAT-2 0.012
egl-36 Protein EGL-36 0.012
tph-1 Protein TPH-1 0.011
lec-5 Protein LEC-5 0.011
slo-2 Protein SLO-2 0.010
grk-2 Protein GRK-2 0.010
ser-2 Protein SER-2 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
ppk pickpocket 0.062
CG13253 CG13253 gene product from transcript CG13253-RB 0.032
Gad1 Glutamic acid decarboxylase 1 0.022
RanBPM Ran-binding protein M 0.022
Tbh Tyramine beta hydroxylase 0.013
CG42629 CG42629 gene product from transcript CG42629-RB 0.012
cpo couch potato 0.011
CrebB-17A Cyclic-AMP response element binding protein B at 17A 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
CARD11 caspase recruitment domain family, member 11 0.624
C9orf89 chromosome 9 open reading frame 89 0.168
BBS2 Bardet-Biedl syndrome 2 0.125
JAK2 Janus kinase 2 0.104
NCOR2 nuclear receptor corepressor 2 0.097
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.091
PTPRB protein tyrosine phosphatase, receptor type, B 0.079
KAT2B K(lysine) acetyltransferase 2B 0.068
PDPK1 3-phosphoinositide dependent protein kinase-1 0.061
RARA retinoic acid receptor, alpha 0.057
BBS1 Bardet-Biedl syndrome 1 0.054
EPOR erythropoietin receptor 0.051
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.046
NCOR1 nuclear receptor corepressor 1 0.045
DEPTOR DEP domain containing MTOR-interacting protein 0.039
CHD9 chromodomain helicase DNA binding protein 9 0.039
DCTN1 dynactin 1 0.036
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.035
TTC8 tetratricopeptide repeat domain 8 0.035
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 0.033
BBS9 Bardet-Biedl syndrome 9 0.031
PRR5 proline rich 5 (renal) 0.027
EXOC7 exocyst complex component 7 0.026
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.022
CCKBR cholecystokinin B receptor 0.022
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.020
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.020
IL12RB2 interleukin 12 receptor, beta 2 0.020
MAP1S microtubule-associated protein 1S 0.020
IGF1R insulin-like growth factor 1 receptor 0.020
PTPN9 protein tyrosine phosphatase, non-receptor type 9 0.020
RHEB Ras homolog enriched in brain 0.019
AKT1S1 AKT1 substrate 1 (proline-rich) 0.019
ALDOB aldolase B, fructose-bisphosphate 0.018
PRR5L proline rich 5 like 0.018
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.018
TRIM11 tripartite motif containing 11 0.017
INSR insulin receptor 0.017
AR androgen receptor 0.017
PCM1 pericentriolar material 1 0.017
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.016
RHEBL1 Ras homolog enriched in brain like 1 0.016
PGR progesterone receptor 0.014
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.014
MED25 mediator complex subunit 25 0.013
TELO2 TEL2, telomere maintenance 2, homolog (S. cerevisiae) 0.013
MAPK11 mitogen-activated protein kinase 11 0.013
NCOA1 nuclear receptor coactivator 1 0.012
JAK3 Janus kinase 3 0.012
ASXL1 additional sex combs like 1 (Drosophila) 0.011
HSCB HscB iron-sulfur cluster co-chaperone homolog (E. coli) 0.011
C1orf93 chromosome 1 open reading frame 93 0.011
CREBBP CREB binding protein 0.011
MED15 mediator complex subunit 15 0.011
BBS7 Bardet-Biedl syndrome 7 0.011
ARL6 ADP-ribosylation factor-like 6 0.011
FOXO3 forkhead box O3 0.011
LRRK2 leucine-rich repeat kinase 2 0.010
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.010
THEM4 thioesterase superfamily member 4 0.010
MRVI1 murine retrovirus integration site 1 homolog 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Lepr leptin receptor 0.938
Nos1 nitric oxide synthase 1, neuronal 0.935
Bbs4 Bardet-Biedl syndrome 4 (human) 0.862
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.657
LOC100048884 novel member of the major urinary protein (Mup) gene family 0.611
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 0.566
Lep leptin 0.564
Mup10 major urinary protein 10 0.538
Pparg peroxisome proliferator activated receptor gamma 0.476
Bbs2 Bardet-Biedl syndrome 2 (human) 0.468
Bbs1 Bardet-Biedl syndrome 1 (human) 0.395
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.356
Prlr prolactin receptor 0.291
Mup19 major urinary protein 19 0.279
Mup9 major urinary protein 9 0.272
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.267
Ghr growth hormone receptor 0.265
Esr1 estrogen receptor 1 (alpha) 0.255
Mup4 major urinary protein 4 0.240
Insr insulin receptor 0.227
Mup14 major urinary protein 14 0.200
Pomc pro-opiomelanocortin-alpha 0.179
Mup7 major urinary protein 7 0.178
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.169
Mup17 major urinary protein 17 0.156
Cav1 caveolin 1, caveolae protein 0.155
Mup15 major urinary protein 15 0.152
Mup1 major urinary protein 1 0.151
Lhx3 LIM homeobox protein 3 0.148
Mup8 major urinary protein 8 0.140
Ghrhr growth hormone releasing hormone receptor 0.115
Mup12 major urinary protein 12 0.111
Mup13 major urinary protein 13 0.098
Mup11 major urinary protein 11 0.098
Mup2 major urinary protein 2 0.096
LOC100048885 major urinary protein LOC100048885 0.093
Plin1 perilipin 1 0.091
Chrng cholinergic receptor, nicotinic, gamma polypeptide 0.082
Apoe apolipoprotein E 0.079
Chrna10 cholinergic receptor, nicotinic, alpha polypeptide 10 0.078
Stat3 signal transducer and activator of transcription 3 0.075
Drd2 dopamine receptor D2 0.074
Chrna9 cholinergic receptor, nicotinic, alpha polypeptide 9 0.067
Gnao1 guanine nucleotide binding protein, alpha O 0.065
Gh growth hormone 0.062
Ldb3 LIM domain binding 3 0.059
Npy1r neuropeptide Y receptor Y1 0.056
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.051
Smyd1 SET and MYND domain containing 1 0.051
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.050
Ptprn protein tyrosine phosphatase, receptor type, N 0.046
S100a5 S100 calcium binding protein A5 0.044
Mup3 major urinary protein 3 0.043
Wwox WW domain-containing oxidoreductase 0.042
Vhl von Hippel-Lindau tumor suppressor 0.042
Gnb3 guanine nucleotide binding protein (G protein), beta 3 0.042
Il6st interleukin 6 signal transducer 0.040
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.039
Hbb-b1 hemoglobin, beta adult major chain 0.038
Onecut1 one cut domain, family member 1 0.037
Obp1a odorant binding protein Ia 0.037
Prss30 protease, serine, 30 0.037
Il5 interleukin 5 0.036
Orm3 orosomucoid 3 0.035
Npy2r neuropeptide Y receptor Y2 0.034
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.032
Gabrr1 gamma-aminobutyric acid (GABA) C receptor, subunit rho 1 0.032
Jak2 Janus kinase 2 0.032
Crygs crystallin, gamma S 0.031
Scd1 stearoyl-Coenzyme A desaturase 1 0.031
Gzmm granzyme M (lymphocyte met-ase 1) 0.031
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.030
Ache acetylcholinesterase 0.030
Kiss1r KISS1 receptor 0.030
Klk1b1 kallikrein 1-related peptidase b1 0.029
Kl klotho 0.029
Pde6b phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide 0.029
Agrp agouti related protein 0.029
Kcnk4 potassium channel, subfamily K, member 4 0.028
Il9r interleukin 9 receptor 0.027
Mybph myosin binding protein H 0.026
Thrb thyroid hormone receptor beta 0.026
Mup5 major urinary protein 5 0.026
Wdr1 WD repeat domain 1 0.026
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.025
Grpr gastrin releasing peptide receptor 0.025
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.024
Krt33b keratin 33B 0.024
Lpar5 lysophosphatidic acid receptor 5 0.023
Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 0.023
Ccbp2 chemokine binding protein 2 0.023
Otc ornithine transcarbamylase 0.023
Irs2 insulin receptor substrate 2 0.022
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.022
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.022
Cps1 carbamoyl-phosphate synthetase 1 0.021
Glycam1 glycosylation dependent cell adhesion molecule 1 0.021
Myf6 myogenic factor 6 0.020
Dmbt1 deleted in malignant brain tumors 1 0.020
Prlhr prolactin releasing hormone receptor 0.020
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Rattus norvegicus
Name Description Probability Func Analog Organism
Pnlip pancreatic lipase 0.454
Omp olfactory marker protein 0.348
Pnliprp2 pancreatic lipase-related protein 2 0.314
Avp arginine vasopressin 0.268
Arhgap23 Rho GTPase activating protein 23 0.239
Zg16 zymogen granule protein 16 0.192
Fam83f family with sequence similarity 83, member F 0.188
Cish cytokine inducible SH2-containing protein 0.177
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.173
Car5a carbonic anhydrase 5a, mitochondrial 0.157
Ctla4 cytotoxic T-lymphocyte-associated protein 4 0.146
Hcrt hypocretin 0.128
Prap1 proline-rich acidic protein 1 0.127
Gjb5 gap junction protein, beta 5 0.126
Gip gastric inhibitory polypeptide 0.125
Chat choline acetyltransferase 0.122
Vgf VGF nerve growth factor inducible 0.121
Hand1 heart and neural crest derivatives expressed 1 0.115
LOC680122 similar to sin3 associated polypeptide 0.105
Ahsg alpha-2-HS-glycoprotein 0.096
Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 0.096
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.092
Ppy pancreatic polypeptide 0.089
Aqp2 aquaporin 2 (collecting duct) 0.088
Amn amnionless homolog (mouse) 0.085
Accn3 amiloride-sensitive cation channel 3 0.082
Gabre gamma-aminobutyric acid (GABA) A receptor, epsilon 0.081
Cd36 CD36 molecule (thrombospondin receptor) 0.077
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.077
Cckbr cholecystokinin B receptor 0.077
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.076
Tpbpa trophoblast specific protein alpha 0.074
LOC246267 resection-induced TPI (rs11) 0.073
Egr4 early growth response 4 0.072
Sst somatostatin 0.071
Prss3 protease, serine, 3 0.071
Th tyrosine hydroxylase 0.071
Pla2g1b phospholipase A2, group IB, pancreas 0.071
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.071
Cela2a chymotrypsin-like elastase family, member 2A 0.067
Casr calcium-sensing receptor 0.066
Cnga3 cyclic nucleotide gated channel alpha 3 0.066
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.064
Cpb1 carboxypeptidase B1 (tissue) 0.063
Fgf5 fibroblast growth factor 5 0.061
Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 0.061
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.059
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.058
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.057
Igfals insulin-like growth factor binding protein, acid labile subunit 0.056
Agxt alanine-glyoxylate aminotransferase 0.055
Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 0.055
Cga glycoprotein hormones, alpha polypeptide 0.053
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.049
Gal galanin prepropeptide 0.049
Foxe3 forkhead box E3 0.048
Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 0.046
Hapln2 hyaluronan and proteoglycan link protein 2 0.046
Fabp1 fatty acid binding protein 1, liver 0.046
Foxd3 forkhead box D3 0.045
Chrm1 cholinergic receptor, muscarinic 1 0.045
Ctrb1 chymotrypsinogen B1 0.045
Uox urate oxidase 0.045
LOC100361261 rCG23560-like 0.045
Mc4r melanocortin 4 receptor 0.043
Hpd 4-hydroxyphenylpyruvate dioxygenase 0.041
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.041
Gulo gulonolactone (L-) oxidase 0.041
Isl2 ISL LIM homeobox 2 0.040
Gcm1 glial cells missing homolog 1 (Drosophila) 0.040
Asgr1 asialoglycoprotein receptor 1 0.040
Treh trehalase (brush-border membrane glycoprotein) 0.039
Ghr growth hormone receptor 0.038
Atp4a ATPase, H+/K+ exchanging, alpha polypeptide 0.038
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.038
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.037
LOC60591 calcium-activated potassium channel beta subunit 0.037
Cnga4 cyclic nucleotide gated channel alpha 4 0.037
Gja3 gap junction protein, alpha 3 0.037
Hal histidine ammonia lyase 0.037
Slc6a18 solute carrier family 6, member 18 0.036
Onecut1 one cut homeobox 1 0.036
Fbp1 fructose-1,6-bisphosphatase 1 0.035
Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 0.034
Sult1e1 sulfotransferase family 1E, estrogen-preferring, member 1 0.034
Pyy peptide YY (mapped) 0.034
Pga5 pepsinogen 5, group I 0.033
Mog myelin oligodendrocyte glycoprotein 0.033
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.033
Mettl7b methyltransferase like 7B 0.033
Chrne cholinergic receptor, nicotinic, epsilon 0.033
Fxyd4 FXYD domain-containing ion transport regulator 4 0.033
Il8rb interleukin 8 receptor, beta 0.032
Fgf17 fibroblast growth factor 17 0.032
Drd2 dopamine receptor D2 0.032
Ppyr1 pancreatic polypeptide receptor 1 0.032
Agtr1a angiotensin II receptor, type 1a 0.032
Aqp8 aquaporin 8 0.032
Socs3 suppressor of cytokine signaling 3 0.031
A1i3 alpha-1-inhibitor III 0.031
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism