|
|
modified amino acid transport
|
GO:0072337 |
11 |
1.000
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.998
|
|
|
|
adenylate cyclase activating dopamine receptor signaling pathway
|
GO:0007191 |
3 |
0.991
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.983
|
|
|
|
amino acid betaine transport
|
GO:0015838 |
4 |
0.938
|
|
|
|
negative regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010642 |
4 |
0.908
|
|
|
|
regulation of cyclase activity
|
GO:0031279 |
19 |
0.903
|
|
|
|
phospholipase c activating dopamine receptor signaling pathway
|
GO:0060158 |
2 |
0.901
|
|
|
|
renal sodium ion transport
|
GO:0003096 |
2 |
0.883
|
|
|
|
activation of mapk activity by adrenergic receptor signaling pathway
|
GO:0071883 |
3 |
0.818
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.809
|
|
|
|
regulation of cgmp metabolic process
|
GO:0030823 |
9 |
0.809
|
|
|
|
regulation of guanylate cyclase activity
|
GO:0031282 |
2 |
0.797
|
|
|
|
sodium ion homeostasis
|
GO:0055078 |
14 |
0.796
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.721
|
|
|
|
negative regulation of cgmp metabolic process
|
GO:0030824 |
1 |
0.708
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.701
|
|
|
|
hair cell differentiation
|
GO:0035315 |
2 |
0.678
|
|
|
|
renal absorption
|
GO:0070293 |
6 |
0.653
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
43 |
0.634
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
15 |
0.624
|
|
|
|
cgmp metabolic process
|
GO:0046068 |
19 |
0.571
|
|
|
|
negative regulation of cyclic nucleotide biosynthetic process
|
GO:0030803 |
10 |
0.556
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.542
|
|
|
|
trivalent inorganic anion homeostasis
|
GO:0072506 |
7 |
0.529
|
|
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.489
|
|
|
|
adenylate cyclase inhibiting serotonin receptor signaling pathway
|
GO:0007198 |
2 |
0.481
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.479
|
|
|
|
bicarbonate transport
|
GO:0015701 |
6 |
0.476
|
|
|
|
microvillus organization
|
GO:0032528 |
2 |
0.467
|
|
|
|
negative regulation of insulin secretion involved in cellular response to glucose stimulus
|
GO:0061179 |
1 |
0.459
|
|
|
|
positive regulation of phosphatidylinositol biosynthetic process
|
GO:0010513 |
3 |
0.449
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.446
|
|
|
|
negative regulation of purine nucleotide biosynthetic process
|
GO:1900372 |
11 |
0.443
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.442
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.401
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.395
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.391
|
|
|
|
negative regulation of lyase activity
|
GO:0051350 |
7 |
0.379
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.374
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.374
|
|
|
|
negative regulation of nucleotide biosynthetic process
|
GO:0030809 |
11 |
0.362
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.356
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.335
|
|
|
|
cellular trivalent inorganic anion homeostasis
|
GO:0072502 |
4 |
0.334
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.315
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.299
|
|
|
|
negative regulation of cyclic nucleotide metabolic process
|
GO:0030800 |
10 |
0.298
|
|
|
|
cellular monovalent inorganic anion homeostasis
|
GO:0030320 |
4 |
0.278
|
|
|
|
positive regulation of vasodilation
|
GO:0045909 |
4 |
0.273
|
|
|
|
inorganic anion transmembrane transport
|
GO:0098661 |
47 |
0.269
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.269
|
|
|
|
negative regulation of cyclase activity
|
GO:0031280 |
6 |
0.269
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.265
|
|
|
|
cellular divalent inorganic anion homeostasis
|
GO:0072501 |
4 |
0.261
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.257
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.255
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.240
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.232
|
|
|
|
cyclic nucleotide mediated signaling
|
GO:0019935 |
26 |
0.230
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.229
|
Human |
|
|
phosphate ion homeostasis
|
GO:0055062 |
7 |
0.229
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.227
|
|
|
|
regulation of lyase activity
|
GO:0051339 |
23 |
0.224
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.223
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.222
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.222
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.222
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.220
|
|
|
|
membrane hyperpolarization
|
GO:0060081 |
1 |
0.219
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.216
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.214
|
Human |
|
|
regulation of sodium proton antiporter activity
|
GO:0032415 |
3 |
0.214
|
|
|
|
divalent inorganic anion homeostasis
|
GO:0072505 |
8 |
0.211
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
40 |
0.201
|
|
|
|
renal system process
|
GO:0003014 |
25 |
0.201
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.200
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.200
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.199
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.198
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.197
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.196
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.195
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.194
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.189
|
|
|
|
cellular anion homeostasis
|
GO:0030002 |
4 |
0.189
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.188
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.187
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
50 |
0.187
|
|
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
2 |
0.183
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.182
|
Human |
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.181
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.179
|
|
|
|
regulation of cgmp biosynthetic process
|
GO:0030826 |
4 |
0.178
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.175
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.169
|
|
|
|
hippo signaling
|
GO:0035329 |
20 |
0.165
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.162
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.161
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.157
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.157
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.152
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.151
|
Human |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.150
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.146
|
|
|
|
camp mediated signaling
|
GO:0019933 |
23 |
0.146
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.144
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.143
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.143
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.142
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.141
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.140
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
41 |
0.139
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.138
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.137
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.136
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.135
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.134
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.133
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.132
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.131
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.131
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.130
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.129
|
|
|
|
amino acid transport
|
GO:0006865 |
28 |
0.129
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.128
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.128
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.126
|
Human |
|
|
negative regulation of purine nucleotide metabolic process
|
GO:1900543 |
28 |
0.126
|
|
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.126
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.125
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.123
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.123
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.123
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.122
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.121
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.121
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.120
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.118
|
|
|
|
regulation of vasodilation
|
GO:0042312 |
4 |
0.118
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.117
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.116
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.115
|
Human |
|
|
vasodilation
|
GO:0042311 |
4 |
0.114
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.112
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.110
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.109
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.109
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.108
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.106
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
22 |
0.105
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.105
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.105
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.104
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.103
|
|
|
|
monovalent inorganic anion homeostasis
|
GO:0055083 |
8 |
0.103
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.102
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.101
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.101
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.099
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.098
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.098
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.098
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.098
|
|
|
|
negative regulation of nucleotide metabolic process
|
GO:0045980 |
29 |
0.097
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.096
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.096
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.096
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.091
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.090
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.090
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.089
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.088
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.088
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.085
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.085
|
Human |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.084
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.084
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.084
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.084
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.084
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.083
|
Human |
|
|
microvillus assembly
|
GO:0030033 |
2 |
0.083
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.083
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.082
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.082
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.081
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.080
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.080
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.079
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.079
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.079
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.079
|
Human |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.078
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.078
|
Human |
|
|
nuclear division
|
GO:0000280 |
128 |
0.078
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.077
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.077
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.076
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.076
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.076
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
52 |
0.075
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.075
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.075
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.074
|
Human |
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.074
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.074
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.074
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.073
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.073
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.072
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.072
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.072
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.071
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.071
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.071
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.070
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.070
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.069
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.068
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.068
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.068
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.068
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.068
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.068
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.067
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.067
|
|
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.067
|
|
|
|
serotonin receptor signaling pathway
|
GO:0007210 |
11 |
0.067
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.066
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.066
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.065
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.065
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.063
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.062
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.062
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.062
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.061
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.061
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.061
|
|
|
|
chloride transmembrane transport
|
GO:1902476 |
38 |
0.061
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.061
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.061
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.061
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.061
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.060
|
|
|
|
regulation of platelet derived growth factor receptor signaling pathway
|
GO:0010640 |
6 |
0.060
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.060
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.059
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.059
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.059
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.059
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.059
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.059
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.058
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.058
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.058
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.058
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.057
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.057
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.057
|
Fly |
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
2 |
0.057
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.057
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.057
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.057
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.056
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.056
|
Human |
|
|
hydrogen transport
|
GO:0006818 |
23 |
0.056
|
|
|
|
negative regulation of platelet aggregation
|
GO:0090331 |
3 |
0.056
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.055
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.055
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.054
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.053
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.053
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.053
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.053
|
Human |
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.052
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.052
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.052
|
Human |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.052
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.052
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.052
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.052
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.051
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.051
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.051
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.050
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.050
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.050
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.050
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.049
|
Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.049
|
|
|
|
chloride transport
|
GO:0006821 |
41 |
0.049
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.049
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.049
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.049
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.048
|
|
|
|
gastro intestinal system smooth muscle contraction
|
GO:0014831 |
2 |
0.048
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.048
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.048
|
|
|
|
regulation of tube size
|
GO:0035150 |
18 |
0.048
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.048
|
Human |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.048
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.047
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.047
|
|
|
|
cgmp biosynthetic process
|
GO:0006182 |
12 |
0.047
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.047
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.047
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.046
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.046
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.046
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.046
|
Human |
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.046
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.046
|
Human |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.046
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.046
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.046
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.045
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.045
|
|
|
|
proton transport
|
GO:0015992 |
22 |
0.045
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.045
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.045
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.045
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.044
|
|
|
|
intestine smooth muscle contraction
|
GO:0014827 |
2 |
0.044
|
|
|
|
regulation of postsynaptic membrane potential
|
GO:0060078 |
1 |
0.044
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.043
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.043
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.043
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.042
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.042
|
|
|
|
adenylate cyclase inhibiting adrenergic receptor signaling pathway
|
GO:0071881 |
1 |
0.042
|
|
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.042
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.042
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.042
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.042
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.042
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.042
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.042
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.041
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.041
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.041
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.041
|
|
|
|
inorganic anion transport
|
GO:0015698 |
60 |
0.041
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.041
|
Human |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.041
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.041
|
Human |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.040
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.040
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.040
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.040
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
6 |
0.040
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.039
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.039
|
Human |
|
|
tube development
|
GO:0035295 |
125 |
0.039
|
Fly |
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.039
|
|
|
|
acid secretion
|
GO:0046717 |
12 |
0.039
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.039
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.039
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.038
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.038
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.038
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.038
|
|
|
|
negative regulation of homotypic cell cell adhesion
|
GO:0034111 |
3 |
0.038
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.038
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.038
|
Human |
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.037
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.037
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.037
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.037
|
|
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.036
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.036
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.036
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.036
|
|
|
|
copulation
|
GO:0007620 |
1 |
0.036
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.036
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.036
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.035
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.035
|
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.035
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.035
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.035
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.035
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.035
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.035
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.035
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.035
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
2 |
0.035
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.034
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.034
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.034
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.033
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.033
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.033
|
|
|
|
endothelial cell development
|
GO:0001885 |
18 |
0.033
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.033
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.033
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.033
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.032
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.032
|
Human |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.032
|
|
|
|
regulation of chloride transport
|
GO:2001225 |
2 |
0.032
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.032
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.032
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.032
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.032
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.032
|
|
|
|
aging
|
GO:0007568 |
66 |
0.032
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.032
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.032
|
Human |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.031
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.031
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.031
|
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.031
|
|
|
|
regulation of proton transport
|
GO:0010155 |
3 |
0.031
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.031
|
Human |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.031
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.031
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.030
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.030
|
Human |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.030
|
|
|
|
startle response
|
GO:0001964 |
3 |
0.030
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.030
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.029
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.029
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.029
|
|
|
|
mating
|
GO:0007618 |
1 |
0.029
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.029
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.029
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.029
|
|
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.029
|
|
|
|
endothelial cell differentiation
|
GO:0045446 |
26 |
0.029
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.029
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.029
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.028
|
|
|
|
growth
|
GO:0040007 |
202 |
0.028
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.028
|
|
|
|
negative regulation of transporter activity
|
GO:0032410 |
25 |
0.028
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.028
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.028
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.028
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.028
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.028
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.027
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
41 |
0.027
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.027
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.027
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.027
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.027
|
|
|
|
negative regulation of ion transmembrane transporter activity
|
GO:0032413 |
19 |
0.027
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.027
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
23 |
0.027
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.027
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.026
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.026
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.026
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.026
|
|
|
|
memory
|
GO:0007613 |
3 |
0.026
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.026
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.026
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.025
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.025
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.025
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.025
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.025
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
3 |
0.025
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.025
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.025
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.025
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.025
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.024
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.024
|
|
|
|
membrane to membrane docking
|
GO:0022614 |
5 |
0.024
|
|
|
|
quaternary ammonium group transport
|
GO:0015697 |
5 |
0.024
|
|
|
|
skeletal muscle tissue growth
|
GO:0048630 |
2 |
0.024
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.024
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.023
|
|
|
|
anion homeostasis
|
GO:0055081 |
18 |
0.023
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.023
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
8 |
0.023
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.023
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.023
|
|
|
|
presynaptic membrane organization
|
GO:0097090 |
3 |
0.023
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.023
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.023
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.023
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.023
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.023
|
|
