IMP

Process View

Homo sapiens

19 genes annotated in human

Multi-species View

cgmp metabolic process

GO:0046068

The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cgmp metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cgmp metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.981
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.833
GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)	0.799	Human Mouse
PDZD3	PDZ domain containing 3	0.648
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.606
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.592
TBC1D10A	TBC1 domain family, member 10A	0.571
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.547	Human
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.406	Human
VEGFA	vascular endothelial growth factor A	0.399
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.305
NOSTRIN	nitric oxide synthase trafficker	0.275
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.258
NRP1	neuropilin 1	0.225
MPDZ	multiple PDZ domain protein	0.225
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.210
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.187
VAC14	Vac14 homolog (S. cerevisiae)	0.178
HP	haptoglobin	0.149
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.126
A2M	alpha-2-macroglobulin	0.119
FZD1	frizzled homolog 1 (Drosophila)	0.110	Human
PTEN	phosphatase and tensin homolog	0.096
PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like	0.083
MT1A	metallothionein 1A	0.080
RGS20	regulator of G-protein signaling 20	0.053
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.050
APOC1	apolipoprotein C-I	0.043
PGF	placental growth factor	0.042	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.041
WNT3A	wingless-type MMTV integration site family, member 3A	0.041	Human
MATK	megakaryocyte-associated tyrosine kinase	0.039
CBX1	chromobox homolog 1	0.037
NDP	Norrie disease (pseudoglioma)	0.036
CALCA	calcitonin-related polypeptide alpha	0.034
COL4A1	collagen, type IV, alpha 1	0.033
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.033
DLG2	discs, large homolog 2 (Drosophila)	0.032
DNM1	dynamin 1	0.032
COL5A1	collagen, type V, alpha 1	0.029
PTK2	PTK2 protein tyrosine kinase 2	0.029
PLXDC1	plexin domain containing 1	0.028
LRP6	low density lipoprotein receptor-related protein 6	0.027
APOC3	apolipoprotein C-III	0.027
MAPT	microtubule-associated protein tau	0.027
ADRB2	adrenergic, beta-2-, receptor, surface	0.025	Human
DTX2	deltex homolog 2 (Drosophila)	0.024
WNT5A	wingless-type MMTV integration site family, member 5A	0.023
PTPRB	protein tyrosine phosphatase, receptor type, B	0.023
LCAT	lecithin-cholesterol acyltransferase	0.022
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.022
LDLR	low density lipoprotein receptor	0.021
BMI1	BMI1 polycomb ring finger oncogene	0.021
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.021
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.021
BBS10	Bardet-Biedl syndrome 10	0.020
ADAMTSL4	ADAMTS-like 4	0.020
SPRR2A	small proline-rich protein 2A	0.019
SLC26A3	solute carrier family 26, member 3	0.018
ARRDC3	arrestin domain containing 3	0.018
TIMP3	TIMP metallopeptidase inhibitor 3	0.017
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.016
KCTD17	potassium channel tetramerisation domain containing 17	0.015
ELF5	E74-like factor 5 (ets domain transcription factor)	0.015
MTNR1B	melatonin receptor 1B	0.014	Human Rat
ALB	albumin	0.014
FZD8	frizzled homolog 8 (Drosophila)	0.014	Human
RAP2B	RAP2B, member of RAS oncogene family	0.014
COL2A1	collagen, type II, alpha 1	0.013
TRIM32	tripartite motif containing 32	0.013
PTPRA	protein tyrosine phosphatase, receptor type, A	0.013
APOE	apolipoprotein E	0.013
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.012	Human
ANGPTL2	angiopoietin-like 2	0.012
PDZK1	PDZ domain containing 1	0.012	Human
WNT2	wingless-type MMTV integration site family member 2	0.012
ACHE	acetylcholinesterase	0.012
NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	0.012
APOA2	apolipoprotein A-II	0.012
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.011
GFI1B	growth factor independent 1B transcription repressor	0.011
FGF2	fibroblast growth factor 2 (basic)	0.011
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.011
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.011
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.011
COL6A1	collagen, type VI, alpha 1	0.011
STC1	stanniocalcin 1	0.011
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.011
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.011
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.011
MDFI	MyoD family inhibitor	0.010
FGF18	fibroblast growth factor 18	0.010
EZR	ezrin	0.010
EGFL7	EGF-like-domain, multiple 7	0.010
VEGFC	vascular endothelial growth factor C	0.010	Human