IMP
Process View
regulation of rig i signaling pathway
Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.
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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of rig i signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.570 | ||
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.536 | Human | |
| IFI44 | interferon-induced protein 44 | 0.533 | ||
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.220 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.171 | ||
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.165 | ||
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.161 | ||
| SP110 | SP110 nuclear body protein | 0.107 | ||
| IFI44L | interferon-induced protein 44-like | 0.099 | ||
| SP100 | SP100 nuclear antigen | 0.081 | ||
| XAF1 | XIAP associated factor 1 | 0.068 | ||
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.065 | ||
| OAS1 | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 0.063 | ||
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.063 | ||
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.051 | ||
| HERC5 | hect domain and RLD 5 | 0.050 | ||
| SAMD9 | sterile alpha motif domain containing 9 | 0.050 | ||
| SAMD9L | sterile alpha motif domain containing 9-like | 0.035 | ||
| TDRD7 | tudor domain containing 7 | 0.030 | ||
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.028 | ||
| MX1 | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 0.028 | ||
| IFIH1 | interferon induced with helicase C domain 1 | 0.028 | Human | |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.023 | Human | |
| TRIM21 | tripartite motif containing 21 | 0.023 | Human | |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.022 | ||
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | 0.021 | ||
| TRIM25 | tripartite motif containing 25 | 0.019 | ||
| PLSCR1 | phospholipid scramblase 1 | 0.018 | ||
| DTX3L | deltex 3-like (Drosophila) | 0.018 | ||
| IRF9 | interferon regulatory factor 9 | 0.018 | ||
| ISG15 | ISG15 ubiquitin-like modifier | 0.016 | ||
| CYLD | cylindromatosis (turban tumor syndrome) | 0.016 | ||
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.014 | ||
| MX2 | myxovirus (influenza virus) resistance 2 (mouse) | 0.014 | ||
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.014 | ||
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.013 | ||
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.012 | Human | |
| TRIM5 | tripartite motif containing 5 | 0.012 | Human | |
| TRIM22 | tripartite motif containing 22 | 0.012 | Human | |
| EIF2C2 | eukaryotic translation initiation factor 2C, 2 | 0.011 | ||
| ADAR | adenosine deaminase, RNA-specific | 0.011 | ||
| IFI16 | interferon, gamma-inducible protein 16 | 0.011 | ||
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.010 | ||
| NMI | N-myc (and STAT) interactor | 0.010 |